spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. (a) siRNA targeting PAK1 or control siRNA oligos were transfected into keratinocytes. Following expression of constitutively active Rac1 (0.5 mg/ml) for 7 hours, siRNA-treated keratinocytes were stained for E-cadherin and the FLAG-tag. Scale bar, 20 µm. (b) Lysates were obtained and probed with antibodies against PAK1, actin and E-cadherin. (c) The rescue of Rac-dependent junction disruption by depletion of endogenous PAK was quantified using the ratio between cadherin staining and junction length (see Materials and Methods). *P<0.05.





Right arrow Return to article