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Figure 6


Fig. 6. Expression of epidermal differentiation markers. Dorsal skin section from FVB/N wild type in late anagen phase (A,D,G,J), and bi-transgenic animals of the F1 line VF1-07 in intermediate stage (B,C,E,F,H,I,K,L). Immunofluorescence with the cytokeratin 1 (CK1), cytokeratin 10 (CK10), filaggrin and loricrin antibodies in green and merged with DAPI (blue). High-magnification view of interfollicular epidermis show expression of CK1 and CK10 in a few cells of the basal layer (C and F, respectively). Transgenic mice were supplied with doxycyline until time of weaning – day 21. BL, basal layer; D, dermis. Scale bars: 50 µm.





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