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Figure 8


Fig. 8. p66Shc forms a complex with p190BRhoGAP in E5- and v-Sis-expressing HDFs. Total Shc (A) or p66Shc (B) was immunoprecipitated (IP) from lysates of HDFs expressing no transgene (control or LXSN-Puro) or the indicated viral oncoprotein in the absence (A) or presence (B) of exogenous wild-type (WT) p66Shc, S36A or empty LXSN. Immunoprecipitates were subjected to immunoblotting for p190B, SHP2 or Shc as indicated.





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