|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
|
Fig. 4. Myosin-II-null cells migrate in a direction counter to the sum of the strain vectors at each spot. (A) The trajectory of a migrating myosin-II-null cell and strain vectors at each point for a period of 400 seconds. The black line is the trajectory of the centroid of a migrating myosin-II-null cell. Each blue line emerging from the trajectory indicates the average strain vector under the cell. The length of the blue lines is 50 times the real strain in the substratum. Blue lines were drawn every 17.5 seconds. The black arrow indicates the direction of migration and represents a length of 1 µm. The trajectory was made from one of the three stress map sequences of myosin-II-null cells. (a-f) Stress maps when the cell was positioned at points a-f in A, respectively. Bar, 3 µm (a). (B) The sequential images of the cell outline at the moment when the cell was at each position marked with asterisks of the same color in panel A. The trajectory in panel B is reduced to one-third in comparison with panel A. Myosin-II-null cells continued to migrate in a direction opposite to the direction of the traction stresses.
|
