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Figure 7


Fig. 7. BDNF mRNA transcripts of exon 4, exon 6 and exon 9a are required for resistance to cytotoxic stress conditions. Viability assay using MTT in SK-N-BE cells treated with each single specific siRNA against BDNF mRNA isoforms at 6 hours of the following treatments. (A) Control medium with 10% FCS. (B) Control medium with cisplatin (CIS). (C) Serum-free medium (SFM) with no drugs. (D) Serum-free medium (SFM) with cisplatin (CIS). Quantification of the viability assay for cells was performed with MTT (each column is the mean ± s.e.m. of n=3 cultures). Statistical analysis was performed with ANOVA (*P<0.05; **P<0.01).





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