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Figure 6


Fig. 6. The Inv C-terminal region contains a ninein homologous region. (A) The C-terminal ninein homologous region is highly conserved. The mouse C-terminal ninein homologous region of Inv is aligned with Inv and ninein from rat and human. Similar characteristic amino acids are in the same color. Numbers indicate the position of the amino acids. (B) Inv (1001-1062) signal (green) is detected at the centrosome and this is confirmed by anti-{gamma}-tubulin staining (red). Line-scan data (right) also shows colocalization of Inv (1001-1062) and {gamma}-tubulin. Scale bar: 10 µm. (C) GFP-tagged ninein (1875-2035) signal (green) is detected at the centrosome and confirmed by anti-{gamma}-tubulin staining (red). Line-scan data (right) also shows the colocalization of GFP-tagged ninein (1875-2035) and {gamma}-tubulin. Scale bar: 10 µm.





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