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Figure 1


Fig. 1. Vesicular and tubular endocytic pathways in the cell. The main uptake pathways involve clathrin-mediated endocytosis (CME), caveolae and clathrin-independent carriers/GPI-enriched endocytic compartments (CLIC/GEEC). Proteins that are involved in carrier formation and/or release are indicated below each pathway. Question marks indicate uncertainties or yet-to-be-established findings. GRAF1 is a recently described BAR-domain protein that marks, and is indispensable for, the CLIC/GEEC pathway (Lundmark et al., 2008).





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