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Figure 1


Fig. 1. Multiple points in the control of cell cycle and fate by integrins. The points in the cell cycle at which integrins have an essential role are shown in pink, and include G1, metaphase and telophase. The fates of daughter cells are also integrin-dependent. They become committed to (a) re-enter the cell cycle, (b) survive or apoptose or (c) express tissue-specific genes and differentiate. (d) In the case of stem cells, one daughter cell will enter the cell cycle and then undergo one of the three fates shown in (a-c), whereas the other will remain a stem cell.





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