JCS041749 Supplementary Material

Files in this Data Supplement:

• Supplemental Figure 1 -

  Fig. S1. Model of C-Half Snail (amino acids 151-264) bound to a small fragment of the human E-cadherin promoter region (-84 to -73) containing the Snail1-binding E-box1 (5′-GGCCGGCAGGTG-3′ and the complementary strand). The model shows that all importin-interacting residues (shown in green) are involved in DNA binding. R191 interacts with G -76 (detail in D), and K161, K170, K187, R220 and R224 interact with the phosphate backbone. The Q239 is too far away to play a role in DNA binding. DNA is shown in grey.