Characterization of the human nestin gene reveals a close evolutionary relationship to neurofilaments

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Dahlstrand, J.
	Articles by Lendahl, U.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Dahlstrand, J.
	Articles by Lendahl, U.


Social Bookmarking

	What's this?

Balcarek, J. M. and Cowan, N. J (1985). Structure of the mouse glial fibrillary acidic protein gene: implications for the evolution of the intermediate filament multigene family. Nucl. Acids Res 13, 5527-5543.[Abstract/Free Full Text]

Bj\232rklund, A (1991). Neural transplantation- an experimental tool with clinical possibilities. Trends Neurosci 14, 319-322.[Medline]

Cattaneo, C. and McKay, R (1990). Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor. Nature 347, 762-765.[Medline]

Ching, G. Y. and Liem, R. K (1991). Structure of the gene for the neuronal intermediate filament protein-internexin and functional analysis of its promoter. J. Biol. Chem 266, 19459-19468.[Abstract/Free Full Text]

Dessev, G. and Goldman, R (1990). The oocyte lamin persists as a single major component of the nuclear lamina during embryonic development of the surf clam. Int. J. Develop. Biol 34, 267-274.[Medline]

Devereux, J., Haeberli, P. and Smithies, O (1984). A comprehensive set of sequence analysis programs for the VAX. Nucl. Acids Res 12, 387-395.

Dodemont, H., Riemer, D. and Weber, K (1990). Sturcture of an invertebrate gene encoding cytoplasmic intermediate filament (IF) proteins: implications for the origin and the diversification of IF proteins. EMBO J 9, 4083-4094.[Medline]

D\232ring, V. and Stick, R (1990). Gene structure of nuclear lamin LIII of Xenopus laevis; a model for the evolution of IF proteins from a lamin-like ancestor. EMBO J 9, 4073-4081.[Medline]

Eckert, R. L. and Green, H (1986). Structure and evolution of the human involucrin gene. Cell 46, 583-589.[Medline]

Feinberg, A. P. and Vogelstein, B (1983). A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem 132, 6-13.[Medline]

Fisher, D. Z., Chaudhary, N. and Blobel, G (1986). cDNA sequencing of nuclear lamins A and C reveals primary and secondary structure homology to intermediate filaments. Proc. Nat. Acad. Sci. USA 83, 6450-6454.[Abstract/Free Full Text]

Frederiksen, K., Jat, J. S., Valtz, N., Levy, D. and McKay, R (1988). Immortalization of precursor cells from the mammalian CNS. Neuron 1, 439-448.[Medline]

Frederiksen, K. and McKay, R (1988). Proliferation and differentiation of rat neuroepithelial precursor cells in vivo. J. Neurosci 8, 1144-1151.[Abstract]

Georgatos, S. D., Maroulakou, I. and Blobel, G (1989). Lamin A, lamin B, and lamin B receptor analogues in yeast. J. Cell Biol 108, 2069-2082.[Abstract/Free Full Text]

Graham, F. O., Smiley, J., Russel, W. and Nairn, R (1977). Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol 36, 59-72.[Abstract/Free Full Text]

Harley, H. G., Brook, J. D., Rundle, S. A., Crow, S., Reardon, W., Buckler, A. J., Harper, P. S., Housman, D. E. and Shaw, D. J (1992). Expansion of unstable DNA region and phenotypic variation in myotonic dystrophy. Nature 355, 545-546.[Medline]

Hockfield, S. and McKay, R (1985). Identification of major cell classes in the developing mammalian nervous system. J. Neurosci 5, 3310-3328.[Abstract]

Ichinose, Y., Morita, T., Zhang, F., Srimahasongeran, S., Tondella, M. L. C., Matsumoto, M., Nozaki, M. and Matsushiro, A (1988). Nucleotide sequence and structure of the mouse cytokeratin endo B gene. Gene 70, 85-95.[Medline]

Jones, C. W. and Kafatos, F. C (1982). Accepted mutations in a gene family: Evolutionary diversification of duplicated DNA. J. Mol. Evol 19, 87-103.[Medline]

Julien, J.-P., C\231te, F., Beaudet, L., Sidky, M., Flavell, D., Grosveld, F. and Mushynski, W (1988). Sequence and structure of the mouse gene coding for the largest neurofilament subunit. Gene 68, 307-314.[Medline]

Julien, J.-P., Grosveld, F., Yazdanbaksh, K., Flavell, D., Meijer, D. and Mushynski, W (1987). The structure of a human neurofilament gene (NF-L): a unique exon-intron organization in the intermediate filament family. Biochim. Biophys. Acta 909, 10-20.[Medline]

Krauss, S. and Franke, W. W (1990). Organization and sequence of the human gene encoding cytokeratin 8. Gene 86, 241-249.[Medline]

Kulesh, D. A. and Oshima, R. G (1988). Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells. Mol. Cell. Biol 8, 1540-1550.[Abstract/Free Full Text]

Lees, J. F., Shneidman, P. S., Skuntz, S. F., Carden, M. J. and Lazzarini, R. A (1988). The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. EMBO J 7, 1947-1955.[Medline]

Lendahl, U., Zimmerman, L. B. and McKay, R. D. G (1990). CNS stem cells express a new class of intermediate filament protein. Cell 60, 585-595.[Medline]

Leonard, D. G. B., Gorham, J. D., Cole, P., Greene, L. A. and Ziff, E. B (1988). A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein. J. Cell Biol 106, 181-193.[Abstract/Free Full Text]

Levy, E., Liem, R. K. H., D'Eustachio, P. and Cowan, N. J (1987). Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein. Eur. J. Biochem 166, 71-77.[Medline]

Lewis, S. A. and Cowan, N. J (1986). Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum. Mol. Cell. Biol 6, 1529-1534.[Abstract/Free Full Text]

McKay, R (1989). The origins of cellular diversity in the mammalian central nervous system. Cell 58, 815-821.[Medline]

Morita, T., Tondella, M. L. C., Takemoto, Y., Hashido, K., Ichinose, Y., Nozaki, M. and Matsushiro, A (1988). Nucleotide sequence of mouse endoA cytokeratin reveals polypeptide characteristics of the type-II keratin subfamily. Gene 68, 109-117.[Medline]

Myers, M. W., Lazzarini, R. A., Lee, V. M.-Y., Schlaepfer, W. W. and Nelson, D. L (1987). The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. EMBO J 6, 1617-1626.[Medline]

Redies, C., Lendahl, U. and McKay, R. D. G (1991). Differentiation and heterogeneity in T-antigen immortalized precursor cell lines from mouse cerebellum. J Neurosci. Res 30, 601-615.[Medline]

Reeves, S. A., Helman, L. J., Allison, A. and Israel, M. A (1989). Molecular cloning and primary structure of human glial fibrillary acidic protein. Proc. Nat. Acad. Sci. USA 86, 5178-5182.[Abstract/Free Full Text]

Renfranz, P. J., Cunningham, M. G. and McKay, R. D. G (1991). Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain. Cell 66, 713-729.[Medline]

Riedel, W. and Werner, D (1989). Nucleotide sequence of the full-length mouse lamin C cDNA and its deduced amino acid sequence. Biochim. Biophys. Acta 1008, 119-122.[Medline]

Smith, G. P (1976). Evolution of repeated DNA sequences by unequal crossover. Science 191, 528-535.[Abstract/Free Full Text]

Snyder, E. Y., Deitcher, D. L., Walsh, C., Arnold-Aldea, S., Hartweig, E. A. and Cepko, C. L (1992). Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 68, 33-51.[Medline]

Steinert, P. M. and Liem, R. K. H (1990). Intermediate filament dynamics. Cell 60, 521-523.[Medline]

Steinert, P. M. and Roop, D. R (1988). Molecular and cellular biology of intermediate filaments. Annu. Rev. Biochem 57, 593-625.[Medline]

Thompson, M. A. and Ziff, E. B (1989). Structure of the gene encoding peripherin, an NGF-regulated neuronal-specific type III intermediate filament protein. Neuron 2, 1043-1053.[Medline]

Tohyama, T., Lee, V. M.-Y., Rorke, L. B., Marvin, M., McKay, R. D. G. and Trojanowski, J (1992). Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells. Lab. Invest 66, 303-313.[Medline]

Vassar, R., Coulombe, P. A., Degenstein, L., Albers, K. and Fuchs, E (1991). Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease. Cell 64, 365-380.[Medline]

Weber, K., Riemer, D. and Dodemont, H (1991). Aspects of the evolution of the lamin/intermediate filament protein family: a current analysis of invertebrate intermediate filament proteins. Biochem. Soc. Trans 19, 1021-1023.[Medline]

Zehner, Z. E (1991). Regulation of intermediate filament gene expression. Curr. Opin. Cell Biol 3, 67-74.[Medline]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

Y.-H. Chou, W.-L. Kuo, M. R. Rosner, W.-J. Tang, and R. D. Goldman
Structural changes in intermediate filament networks alter the activity of insulin-degrading enzyme
FASEB J, November 1, 2009; 23(11): 3734 - 3742.
[Abstract] [Full Text] [PDF]

S Parry, K Savage, C Marchio, and J S Reis-Filho
Nestin is expressed in basal-like and triple negative breast cancers
J. Clin. Pathol., September 1, 2008; 61(9): 1045 - 1050.
[Abstract] [Full Text] [PDF]

A. Mangiola, G. Lama, C. Giannitelli, P. De Bonis, C. Anile, L. Lauriola, G. La Torre, G. Sabatino, G. Maira, M. Jhanwar-Uniyal, et al.
Stem Cell Marker Nestin and c-Jun NH2-Terminal Kinases in Tumor and Peritumor Areas of Glioblastoma Multiforme: Possible Prognostic Implications
Clin. Cancer Res., December 1, 2007; 13(23): 6970 - 6977.
[Abstract] [Full Text] [PDF]

H. Li, P. Cherukuri, N. Li, V. Cowling, M. Spinella, M. Cole, A. K. Godwin, W. Wells, and J. DiRenzo
Nestin Is Expressed in the Basal/Myoepithelial Layer of the Mammary Gland and Is a Selective Marker of Basal Epithelial Breast Tumors
Cancer Res., January 15, 2007; 67(2): 501 - 510.
[Abstract] [Full Text] [PDF]

E. R. Lee, K. W. McCool, F. E. Murdoch, and M. K. Fritsch
Dynamic Changes in Histone H3 Phosphoacetylation during Early Embryonic Stem Cell Differentiation Are Directly Mediated by Mitogen- and Stress-activated Protein Kinase 1 via Activation of MAPK Pathways
J. Biol. Chem., July 28, 2006; 281(30): 21162 - 21172.
[Abstract] [Full Text] [PDF]

J Ehrmann, Z Kolar, and J Mokry
Nestin as a diagnostic and prognostic marker: immunohistochemical analysis of its expression in different tumours
J. Clin. Pathol., February 1, 2005; 58(2): 222 - 223.
[Abstract] [Full Text] [PDF]

S. K. Thomas, C. A. Messam, B. A. Spengler, J. L. Biedler, and R. A. Ross
Nestin Is a Potential Mediator of Malignancy in Human Neuroblastoma Cells
J. Biol. Chem., July 2, 2004; 279(27): 27994 - 27999.
[Abstract] [Full Text] [PDF]

Y.-H. Chou, S. Khuon, H. Herrmann, and R. D. Goldman
Nestin Promotes the Phosphorylation-dependent Disassembly of Vimentin Intermediate Filaments During Mitosis
Mol. Biol. Cell, April 1, 2003; 14(4): 1468 - 1478.
[Abstract] [Full Text] [PDF]

P. M. Almqvist, R. Mah, U. Lendahl, B. Jacobsson, and G. Hendson
Immunohistochemical Detection of Nestin in Pediatric Brain Tumors
J. Histochem. Cytochem., February 1, 2002; 50(2): 147 - 158.
[Abstract] [Full Text] [PDF]

H. Zulewski, E. J. Abraham, M. J. Gerlach, P. B. Daniel, W. Moritz, B. Müller, M. Vallejo, M. K. Thomas, and J. F. Habener
Multipotential Nestin-Positive Stem Cells Isolated From Adult Pancreatic Islets Differentiate Ex Vivo Into Pancreatic Endocrine, Exocrine, and Hepatic Phenotypes
Diabetes, March 1, 2001; 50(3): 521 - 533.
[Abstract] [Full Text]

T. Tsujimura, C. Makiishi-Shimobayashi, J. Lundkvist, U. Lendahl, K. Nakasho, A. Sugihara, T. Iwasaki, M. Mano, N. Yamada, K. Yamashita, et al.
Expression of the Intermediate Filament Nestin in Gastrointestinal Stromal Tumors and Interstitial Cells of Cajal
Am. J. Pathol., March 1, 2001; 158(3): 817 - 823.
[Abstract] [Full Text] [PDF]

R. D. GOLDMAN, Y.-H. CHOU, V. PRAHLAD, and M. YOON
Intermediate filaments: dynamic processes regulating their assembly, motility, and interactions with other cytoskeletal systems
FASEB J, December 1, 1999; 13(9002): 261S - 265S.
[Full Text] [PDF]

P. M. Steinert, Y.-H. Chou, V. Prahlad, D. A.�D. Parry, L. N. Marekov, K. C. Wu, S.-I. Jang, and R. D. Goldman
A High Molecular Weight Intermediate Filament-associated Protein in BHK-21 Cells Is Nestin, a Type VI Intermediate Filament Protein. LIMITED CO-ASSEMBLY IN VITRO TO FORM HETEROPOLYMERS WITH TYPE III VIMENTIN AND TYPE IV alpha -INTERNEXIN
J. Biol. Chem., April 2, 1999; 274(14): 9881 - 9890.
[Abstract] [Full Text] [PDF]

S. Vaittinen, R. Lukka, C. Sahlgren, J. Rantanen, T. Hurme, U. Lendahl, J. E. Eriksson, and H. Kalimo
Specific and Innervation-Regulated Expression of the Intermediate Filament Protein Nestin at Neuromuscular and Myotendinous Junctions in Skeletal Muscle
Am. J. Pathol., February 1, 1999; 154(2): 591 - 600.
[Abstract] [Full Text] [PDF]

S. Sultana, R. Zhou, M. S. Sadagopan, and O. Skalli
Effects of Growth Factors and Basement Membrane Proteins on the Phenotype of U-373 MG Glioblastoma Cells as Determined by the Expression of Intermediate Filament Proteins
Am. J. Pathol., October 1, 1998; 153(4): 1157 - 1168.
[Abstract] [Full Text] [PDF]

P.�B. Crino, J.�Q. Trojanowski, M.�A. Dichter, and J. Eberwine
Embryonic neuronal markers in tuberous sclerosis: Single-cell molecular�pathology
PNAS, November 26, 1996; 93(24): 14152 - 14157.
[Abstract] [Full Text] [PDF]

T Sejersen and U Lendahl
Transient expression of the intermediate filament nestin during skeletal muscle development
J. Cell Sci., January 12, 1993; 106(4): 1291 - 1300.
[Abstract] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Dahlstrand, J.

Articles by Lendahl, U.

Search for Related Content

PubMed

PubMed Citation

Articles by Dahlstrand, J.

Articles by Lendahl, U.

Social Bookmarking

What's this?

				S Parry, K Savage, C Marchio, and J S Reis-Filho Nestin is expressed in basal-like and triple negative breast cancers J. Clin. Pathol., September 1, 2008; 61(9): 1045 - 1050. [Abstract] [Full Text] [PDF]

				A. Mangiola, G. Lama, C. Giannitelli, P. De Bonis, C. Anile, L. Lauriola, G. La Torre, G. Sabatino, G. Maira, M. Jhanwar-Uniyal, et al. Stem Cell Marker Nestin and c-Jun NH2-Terminal Kinases in Tumor and Peritumor Areas of Glioblastoma Multiforme: Possible Prognostic Implications Clin. Cancer Res., December 1, 2007; 13(23): 6970 - 6977. [Abstract] [Full Text] [PDF]

				H. Li, P. Cherukuri, N. Li, V. Cowling, M. Spinella, M. Cole, A. K. Godwin, W. Wells, and J. DiRenzo Nestin Is Expressed in the Basal/Myoepithelial Layer of the Mammary Gland and Is a Selective Marker of Basal Epithelial Breast Tumors Cancer Res., January 15, 2007; 67(2): 501 - 510. [Abstract] [Full Text] [PDF]

				E. R. Lee, K. W. McCool, F. E. Murdoch, and M. K. Fritsch Dynamic Changes in Histone H3 Phosphoacetylation during Early Embryonic Stem Cell Differentiation Are Directly Mediated by Mitogen- and Stress-activated Protein Kinase 1 via Activation of MAPK Pathways J. Biol. Chem., July 28, 2006; 281(30): 21162 - 21172. [Abstract] [Full Text] [PDF]

				J Ehrmann, Z Kolar, and J Mokry Nestin as a diagnostic and prognostic marker: immunohistochemical analysis of its expression in different tumours J. Clin. Pathol., February 1, 2005; 58(2): 222 - 223. [Abstract] [Full Text] [PDF]

				S. K. Thomas, C. A. Messam, B. A. Spengler, J. L. Biedler, and R. A. Ross Nestin Is a Potential Mediator of Malignancy in Human Neuroblastoma Cells J. Biol. Chem., July 2, 2004; 279(27): 27994 - 27999. [Abstract] [Full Text] [PDF]

				Y.-H. Chou, S. Khuon, H. Herrmann, and R. D. Goldman Nestin Promotes the Phosphorylation-dependent Disassembly of Vimentin Intermediate Filaments During Mitosis Mol. Biol. Cell, April 1, 2003; 14(4): 1468 - 1478. [Abstract] [Full Text] [PDF]

				P. M. Almqvist, R. Mah, U. Lendahl, B. Jacobsson, and G. Hendson Immunohistochemical Detection of Nestin in Pediatric Brain Tumors J. Histochem. Cytochem., February 1, 2002; 50(2): 147 - 158. [Abstract] [Full Text] [PDF]

				H. Zulewski, E. J. Abraham, M. J. Gerlach, P. B. Daniel, W. Moritz, B. Müller, M. Vallejo, M. K. Thomas, and J. F. Habener Multipotential Nestin-Positive Stem Cells Isolated From Adult Pancreatic Islets Differentiate Ex Vivo Into Pancreatic Endocrine, Exocrine, and Hepatic Phenotypes Diabetes, March 1, 2001; 50(3): 521 - 533. [Abstract] [Full Text]

				T. Tsujimura, C. Makiishi-Shimobayashi, J. Lundkvist, U. Lendahl, K. Nakasho, A. Sugihara, T. Iwasaki, M. Mano, N. Yamada, K. Yamashita, et al. Expression of the Intermediate Filament Nestin in Gastrointestinal Stromal Tumors and Interstitial Cells of Cajal Am. J. Pathol., March 1, 2001; 158(3): 817 - 823. [Abstract] [Full Text] [PDF]

				R. D. GOLDMAN, Y.-H. CHOU, V. PRAHLAD, and M. YOON Intermediate filaments: dynamic processes regulating their assembly, motility, and interactions with other cytoskeletal systems FASEB J, December 1, 1999; 13(9002): 261S - 265S. [Full Text] [PDF]

				P. M. Steinert, Y.-H. Chou, V. Prahlad, D. A.�D. Parry, L. N. Marekov, K. C. Wu, S.-I. Jang, and R. D. Goldman A High Molecular Weight Intermediate Filament-associated Protein in BHK-21 Cells Is Nestin, a Type VI Intermediate Filament Protein. LIMITED CO-ASSEMBLY IN VITRO TO FORM HETEROPOLYMERS WITH TYPE III VIMENTIN AND TYPE IV alpha -INTERNEXIN J. Biol. Chem., April 2, 1999; 274(14): 9881 - 9890. [Abstract] [Full Text] [PDF]

				S. Vaittinen, R. Lukka, C. Sahlgren, J. Rantanen, T. Hurme, U. Lendahl, J. E. Eriksson, and H. Kalimo Specific and Innervation-Regulated Expression of the Intermediate Filament Protein Nestin at Neuromuscular and Myotendinous Junctions in Skeletal Muscle Am. J. Pathol., February 1, 1999; 154(2): 591 - 600. [Abstract] [Full Text] [PDF]

				S. Sultana, R. Zhou, M. S. Sadagopan, and O. Skalli Effects of Growth Factors and Basement Membrane Proteins on the Phenotype of U-373 MG Glioblastoma Cells as Determined by the Expression of Intermediate Filament Proteins Am. J. Pathol., October 1, 1998; 153(4): 1157 - 1168. [Abstract] [Full Text] [PDF]

				P.�B. Crino, J.�Q. Trojanowski, M.�A. Dichter, and J. Eberwine Embryonic neuronal markers in tuberous sclerosis: Single-cell molecular�pathology PNAS, November 26, 1996; 93(24): 14152 - 14157. [Abstract] [Full Text] [PDF]

				T Sejersen and U Lendahl Transient expression of the intermediate filament nestin during skeletal muscle development J. Cell Sci., January 12, 1993; 106(4): 1291 - 1300. [Abstract] [PDF]