Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

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Am J Physiol Cell Physiol, March 1, 2003; 284(3): C627 - C639.
[Abstract] [Full Text] [PDF]

N. Kataoka, K. Iwaki, K. Hashimoto, S. Mochizuki, Y. Ogasawara, M. Sato, K. Tsujioka, and F. Kajiya
Measurements of endothelial cell-to-cell and cell-to-substrate gaps and micromechanical properties of endothelial cells during monocyte adhesion
PNAS, November 26, 2002; 99(24): 15638 - 15643.
[Abstract] [Full Text] [PDF]

D. E. Ingber
Mechanical Signaling and the Cellular Response to Extracellular Matrix in Angiogenesis and Cardiovascular Physiology
Circ. Res., November 15, 2002; 91(10): 877 - 887.
[Abstract] [Full Text] [PDF]

G. T. Charras and M. A. Horton
Determination of Cellular Strains by Combined Atomic Force Microscopy and Finite Element Modeling
Biophys. J., August 1, 2002; 83(2): 858 - 879.
[Abstract] [Full Text] [PDF]

K. K. PARKER, A. L. BROCK, C. BRANGWYNNE, R. J. MANNIX, N. WANG, E. OSTUNI, N. A. GEISSE, J. C. ADAMS, G. M. WHITESIDES, and D. E. INGBER
Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces
FASEB J, August 1, 2002; 16(10): 1195 - 1204.
[Abstract] [Full Text] [PDF]

G. T. Charras and M. A. Horton
Single Cell Mechanotransduction and Its Modulation Analyzed by Atomic Force Microscope Indentation
Biophys. J., June 1, 2002; 82(6): 2970 - 2981.
[Abstract] [Full Text] [PDF]

K. Bloom
Yeast weighs in on the elusive spindle matrix: New filaments in the nucleus
PNAS, April 16, 2002; 99(8): 4757 - 4759.
[Full Text] [PDF]

E. K. Asem, W. Qin, and S. G. Rane
Effect of basal lamina of ovarian follicle on T- and L-type Ca2+ currents in differentiated granulosa cells
Am J Physiol Endocrinol Metab, January 1, 2002; 282(1): E184 - E196.
[Abstract] [Full Text] [PDF]

D. A. Flusberg, Y. Numaguchi, and D. E. Ingber
Cooperative Control of Akt Phosphorylation, bcl-2 Expression, and Apoptosis by Cytoskeletal Microfilaments and Microtubules in Capillary Endothelial Cells
Mol. Biol. Cell, October 1, 2001; 12(10): 3087 - 3094.
[Abstract] [Full Text] [PDF]

A. D. Verin, A. Birukova, P. Wang, F. Liu, P. Becker, K. Birukov, and J. G. N. Garcia
Microtubule disassembly increases endothelial cell barrier dysfunction: role of MLC phosphorylation
Am J Physiol Lung Cell Mol Physiol, September 1, 2001; 281(3): L565 - L574.
[Abstract] [Full Text] [PDF]

M. R. Moalli, S. Wang, N. J. Caldwell, P. V. Patil, and C. R. Maynard
Mechanical stimulation induces pp125FAK and pp60src activity in an in vivo model of trabecular bone formation
J Appl Physiol, August 1, 2001; 91(2): 912 - 918.
[Abstract] [Full Text] [PDF]

N. Wang, K. Naruse, D. Stamenovic', J. J. Fredberg, S. M. Mijailovich, I. M. Tolic'-Norrelykke, T. Polte, R. Mannix, and D. E. Ingber
Mechanical behavior in living cells consistent with the tensegrity model
PNAS, July 3, 2001; 98(14): 7765 - 7770.
[Abstract] [Full Text] [PDF]

A. RayChaudhury, M. Elkins, D. Kozien, and M. T. Nakada
Regulation of PECAM-1 in Endothelial Cells during Cell Growth and Migration
Experimental Biology and Medicine, July 1, 2001; 226(7): 686 - 691.
[Abstract] [Full Text] [PDF]

J. Chen, B. Fabry, E. L. Schiffrin, and N. Wang
Twisting integrin receptors increases endothelin-1 gene expression in endothelial cells
Am J Physiol Cell Physiol, June 1, 2001; 280(6): C1475 - C1484.
[Abstract] [Full Text] [PDF]

O. P. Hamill and B. Martinac
Molecular Basis of Mechanotransduction in Living Cells
Physiol Rev, April 1, 2001; 81(2): 685 - 740.
[Abstract] [Full Text] [PDF]

M. J. Davis, X. Wu, T. R. Nurkiewicz, J. Kawasaki, G. E. Davis, M. A. Hill, and G. A. Meininger
Integrins and mechanotransduction of the vascular myogenic response
Am J Physiol Heart Circ Physiol, April 1, 2001; 280(4): H1427 - H1433.
[Abstract] [Full Text] [PDF]

C. Krawczyk and J. M. Penninger
Molecular motors involved in T cell receptor clusterings
J. Leukoc. Biol., March 1, 2001; 69(3): 317 - 330.
[Abstract] [Full Text]

A. J. Putnam, K. Schultz, and D. J. Mooney
Control of microtubule assembly by extracellular matrix and externally applied strain
Am J Physiol Cell Physiol, March 1, 2001; 280(3): C556 - C564.
[Abstract] [Full Text] [PDF]

T. L. Yoder, H.-q. Zheng, P. Todd, and L. A. Staehelin
Amyloplast Sedimentation Dynamics in Maize Columella Cells Support a New Model for the Gravity-Sensing Apparatus of Roots
Plant Physiology, February 1, 2001; 125(2): 1045 - 1060.
[Abstract] [Full Text]

W. Li, A. Duzgun, B. E. Sumpio, and M. D. Basson
Integrin and FAK-mediated MAPK activation is required for cyclic strain mitogenic effects in Caco-2 cells
Am J Physiol Gastrointest Liver Physiol, January 1, 2001; 280(1): G75 - G87.
[Abstract] [Full Text] [PDF]

				E. Arciniegas, M. G. Frid, I. S. Douglas, and K. R. Stenmark Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension Am J Physiol Lung Cell Mol Physiol, July 1, 2007; 293(1): L1 - L8. [Abstract] [Full Text] [PDF]

				R. Blumenfeld Isostaticity and Controlled Force Transmission in the Cytoskeleton: A Model Awaiting Experimental Evidence Biophys. J., September 1, 2006; 91(5): 1970 - 1983. [Abstract] [Full Text] [PDF]

				J. L. Martin-Ventura, V. Nicolas, X. Houard, L. M. Blanco-Colio, A. Leclercq, J. Egido, R. Vranckx, J.-B. Michel, and O. Meilhac Biological Significance of Decreased HSP27 in Human Atherosclerosis Arterioscler. Thromb. Vasc. Biol., June 1, 2006; 26(6): 1337 - 1343. [Abstract] [Full Text] [PDF]

				D. Mehta and A. B. Malik Signaling Mechanisms Regulating Endothelial Permeability Physiol Rev, January 1, 2006; 86(1): 279 - 367. [Abstract] [Full Text] [PDF]

				Z. Ma and K. H. Hasenstein The Onset of Gravisensitivity in the Embryonic Root of Flax Plant Physiology, January 1, 2006; 140(1): 159 - 166. [Abstract] [Full Text] [PDF]

				M. M. Hossain, J. F. Crish, R. L. Eckert, J. J.-C. Lin, and J.-P. Jin h2-calponin Is Regulated by Mechanical Tension and Modifies the Function of Actin Cytoskeleton J. Biol. Chem., December 23, 2005; 280(51): 42442 - 42453. [Abstract] [Full Text] [PDF]

				M. Simpson-Holley, R. C. Colgrove, G. Nalepa, J. W. Harper, and D. M. Knipe Identification and Functional Evaluation of Cellular and Viral Factors Involved in the Alteration of Nuclear Architecture during Herpes Simplex Virus 1 Infection J. Virol., October 15, 2005; 79(20): 12840 - 12851. [Abstract] [Full Text] [PDF]

				M. Palmieri and J. Z. Kiss Disruption of the F-actin cytoskeleton limits statolith movement in Arabidopsis hypocotyls J. Exp. Bot., September 1, 2005; 56(419): 2539 - 2550. [Abstract] [Full Text] [PDF]

				N. D. Searby, C. R. Steele, and R. K. Globus Influence of increased mechanical loading by hypergravity on the microtubule cytoskeleton and prostaglandin E2 release in primary osteoblasts Am J Physiol Cell Physiol, July 1, 2005; 289(1): C148 - C158. [Abstract] [Full Text] [PDF]

				H. Huang, J. Sylvan, M. Jonas, R. Barresi, P. T. C. So, K. P. Campbell, and R. T. Lee Cell stiffness and receptors: evidence for cytoskeletal subnetworks Am J Physiol Cell Physiol, January 1, 2005; 288(1): C72 - C80. [Abstract] [Full Text] [PDF]

				G. T. Charras, B. A. Williams, S. M. Sims, and M. A. Horton Estimating the Sensitivity of Mechanosensitive Ion Channels to Membrane Strain and Tension Biophys. J., October 1, 2004; 87(4): 2870 - 2884. [Abstract] [Full Text] [PDF]

				M. Hughes-Fulford Signal Transduction and Mechanical Stress Sci. Signal., September 7, 2004; 2004(249): re12 - re12. [Abstract] [Full Text] [PDF]

				M. H. Ali, D. P. Pearlstein, C. E. Mathieu, and P. T. Schumacker Mitochondrial requirement for endothelial responses to cyclic strain: implications for mechanotransduction Am J Physiol Lung Cell Mol Physiol, September 1, 2004; 287(3): L486 - L496. [Abstract] [Full Text] [PDF]

				A. Bronstad, A. Berg, and R. K. Reed Effects of the taxanes paclitaxel and docetaxel on edema formation and interstitial fluid pressure Am J Physiol Heart Circ Physiol, August 1, 2004; 287(2): H963 - H968. [Abstract] [Full Text] [PDF]

				G. Forgacs, S. H. Yook, P. A. Janmey, H. Jeong, and C. G. Burd Role of the cytoskeleton in signaling networks J. Cell Sci., June 1, 2004; 117(13): 2769 - 2775. [Abstract] [Full Text] [PDF]

				A. Geitmann, W. McConnaughey, I. Lang-Pauluzzi, V. E. Franklin-Tong, and A. M. C. Emons Cytomechanical Properties of Papaver Pollen Tubes Are Altered after Self-Incompatibility Challenge Biophys. J., May 1, 2004; 86(5): 3314 - 3323. [Abstract] [Full Text] [PDF]

				R. A. Meiss and R. M. Pidaparti Mechanical state of airway smooth muscle at very short lengths J Appl Physiol, February 1, 2004; 96(2): 655 - 667. [Abstract] [Full Text] [PDF]

				D. S. Fudge, K. H. Gardner, V. T. Forsyth, C. Riekel, and J. M. Gosline The Mechanical Properties of Hydrated Intermediate Filaments: Insights from Hagfish Slime Threads Biophys. J., September 1, 2003; 85(3): 2015 - 2027. [Abstract] [Full Text] [PDF]

				B. M. Mazzag, J. S. Tamaresis, and A. I. Barakat A Model for Shear Stress Sensing and Transmission in Vascular Endothelial Cells Biophys. J., June 1, 2003; 84(6): 4087 - 4101. [Abstract] [Full Text] [PDF]

				D. E. Ingber Tensegrity I. Cell structure and hierarchical systems biology J. Cell Sci., April 1, 2003; 116(7): 1157 - 1173. [Abstract] [Full Text] [PDF]

				S. R. Bisgrove, D. C. Henderson, and D. L. Kropf Asymmetric Division in Fucoid Zygotes Is Positioned by Telophase Nuclei PLANT CELL, April 1, 2003; 15(4): 854 - 862. [Abstract] [Full Text] [PDF]

				A. J. Putnam, J. J. Cunningham, B. B. L. Pillemer, and D. J. Mooney External mechanical strain regulates membrane targeting of Rho GTPases by controlling microtubule assembly Am J Physiol Cell Physiol, March 1, 2003; 284(3): C627 - C639. [Abstract] [Full Text] [PDF]

				N. Kataoka, K. Iwaki, K. Hashimoto, S. Mochizuki, Y. Ogasawara, M. Sato, K. Tsujioka, and F. Kajiya Measurements of endothelial cell-to-cell and cell-to-substrate gaps and micromechanical properties of endothelial cells during monocyte adhesion PNAS, November 26, 2002; 99(24): 15638 - 15643. [Abstract] [Full Text] [PDF]

				D. E. Ingber Mechanical Signaling and the Cellular Response to Extracellular Matrix in Angiogenesis and Cardiovascular Physiology Circ. Res., November 15, 2002; 91(10): 877 - 887. [Abstract] [Full Text] [PDF]

				G. T. Charras and M. A. Horton Determination of Cellular Strains by Combined Atomic Force Microscopy and Finite Element Modeling Biophys. J., August 1, 2002; 83(2): 858 - 879. [Abstract] [Full Text] [PDF]

				K. K. PARKER, A. L. BROCK, C. BRANGWYNNE, R. J. MANNIX, N. WANG, E. OSTUNI, N. A. GEISSE, J. C. ADAMS, G. M. WHITESIDES, and D. E. INGBER Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces FASEB J, August 1, 2002; 16(10): 1195 - 1204. [Abstract] [Full Text] [PDF]

				G. T. Charras and M. A. Horton Single Cell Mechanotransduction and Its Modulation Analyzed by Atomic Force Microscope Indentation Biophys. J., June 1, 2002; 82(6): 2970 - 2981. [Abstract] [Full Text] [PDF]

				K. Bloom Yeast weighs in on the elusive spindle matrix: New filaments in the nucleus PNAS, April 16, 2002; 99(8): 4757 - 4759. [Full Text] [PDF]

				E. K. Asem, W. Qin, and S. G. Rane Effect of basal lamina of ovarian follicle on T- and L-type Ca2+ currents in differentiated granulosa cells Am J Physiol Endocrinol Metab, January 1, 2002; 282(1): E184 - E196. [Abstract] [Full Text] [PDF]

				D. A. Flusberg, Y. Numaguchi, and D. E. Ingber Cooperative Control of Akt Phosphorylation, bcl-2 Expression, and Apoptosis by Cytoskeletal Microfilaments and Microtubules in Capillary Endothelial Cells Mol. Biol. Cell, October 1, 2001; 12(10): 3087 - 3094. [Abstract] [Full Text] [PDF]