Nanomelic chondrocytes synthesize, but fail to translocate, a truncated aggrecan precursor

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				T.-l. L. Chen, C. Chen, N. Q. Bergeron, B. E. Close, T. J. Bohrer, B. M. Vertel, and K. J. Colley The two rat {alpha}2,6-sialyltransferase (ST6Gal I) isoforms: evaluation of catalytic activity and intra-Golgi localization Glycobiology, February 1, 2003; 13(2): 109 - 117. [Abstract] [Full Text] [PDF]

				N. B. Schwartz and M. Domowicz Chondrodysplasias due to proteoglycan defects Glycobiology, April 1, 2002; 12(4): 57R - 68R. [Abstract] [Full Text] [PDF]

				J. M. Day, A. D. Murdoch, and T. E. Hardingham The Folded Protein Modules of the C-terminal G3 Domain of Aggrecan Can Each Facilitate the Translocation and Secretion of the Extended Chondroitin Sulfate Attachment Sequence J. Biol. Chem., December 31, 1999; 274(53): 38107 - 38111. [Abstract] [Full Text] [PDF]

				N. Itano, T. Sawai, M. Yoshida, P. Lenas, Y. Yamada, M. Imagawa, T. Shinomura, M. Hamaguchi, Y. Yoshida, Y. Ohnuki, et al. Three Isoforms of Mammalian Hyaluronan Synthases Have Distinct Enzymatic Properties J. Biol. Chem., August 27, 1999; 274(35): 25085 - 25092. [Abstract] [Full Text] [PDF]

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				W. Luo, T. S. Kuwada, L. Chandrasekaran, J. Zheng, and M. L. Tanzer Divergent Secretory Behavior of the Opposite Ends of Aggrecan J. Biol. Chem., July 12, 1996; 271(28): 16447 - 16450. [Abstract] [Full Text] [PDF]

				B. L. Yang, L. Cao, C. Kiani, V. Lee, Y. Zhang, M. E. Adams, and B. B. Yang Tandem Repeats Are Involved in G1 Domain Inhibition of Versican Expression and Secretion and the G3 Domain Enhances Glycosaminoglycan Modification and Product Secretion via the Complement-binding Protein-like Motif J. Biol. Chem., July 7, 2000; 275(28): 21255 - 21261. [Abstract] [Full Text] [PDF]

				M. S. Domowicz, E. W. Pirok III, T. E. Novak, and N. B. Schwartz Role of the C-terminal G3 Domain in Sorting and Secretion of Aggrecan Core Protein and Ubiquitin-mediated Degradation of Accumulated Mutant Precursors J. Biol. Chem., November 3, 2000; 275(45): 35098 - 35105. [Abstract] [Full Text] [PDF]

				L. Chen, Y. Wu, V. Lee, C. Kiani, M. E. Adams, Y. Yao, and B. B. Yang The Folded Modules of Aggrecan G3 Domain Exert Two Separable Functions in Glycosaminoglycan Modification and Product Secretion J. Biol. Chem., January 18, 2002; 277(4): 2657 - 2665. [Abstract] [Full Text] [PDF]