The processing pathway of prelamin A

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				J. Barrowman, C. Hamblet, C. M. George, and S. Michaelis Analysis of Prelamin A Biogenesis Reveals the Nucleus to be a CaaX Processing Compartment Mol. Biol. Cell, December 1, 2008; 19(12): 5398 - 5408. [Abstract] [Full Text] [PDF]

				L. B. Gordon, C. J. Harling-Berg, and F. G. Rothman Highlights of the 2007 Progeria Research Foundation Scientific Workshop: Progress in Translational Science J. Gerontol. A Biol. Sci. Med. Sci., August 1, 2008; 63(8): 777 - 787. [Full Text] [PDF]

				S. A. Adam, K. Sengupta, and R. D. Goldman Regulation of Nuclear Lamin Polymerization by Importin {alpha} J. Biol. Chem., March 28, 2008; 283(13): 8462 - 8468. [Abstract] [Full Text] [PDF]

				B. C. Capell, F. S. Collins, and E. G. Nabel Mechanisms of Cardiovascular Disease in Accelerated Aging Syndromes Circ. Res., July 6, 2007; 101(1): 13 - 26. [Abstract] [Full Text] [PDF]

				K. Cao, B. C. Capell, M. R. Erdos, K. Djabali, and F. S. Collins A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells PNAS, March 20, 2007; 104(12): 4949 - 4954. [Abstract] [Full Text] [PDF]

				T. Dechat, T. Shimi, S. A. Adam, A. E. Rusinol, D. A. Andres, H. P. Spielmann, M. S. Sinensky, and R. D. Goldman Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging PNAS, March 20, 2007; 104(12): 4955 - 4960. [Abstract] [Full Text] [PDF]

				Y. Liu, A. Rusinol, M. Sinensky, Y. Wang, and Y. Zou DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A J. Cell Sci., November 15, 2006; 119(22): 4644 - 4649. [Abstract] [Full Text] [PDF]

				A. E. Rusinol and M. S. Sinensky Farnesylated lamins, progeroid syndromes and farnesyl transferase inhibitors. J. Cell Sci., August 15, 2006; 119(Pt 16): 3265 - 3272. [Abstract] [Full Text] [PDF]

				J. L. V. Broers, F. C. S. Ramaekers, G. Bonne, R. B. Yaou, and C. J. Hutchison Nuclear lamins: laminopathies and their role in premature ageing. Physiol Rev, July 1, 2006; 86(3): 967 - 1008. [Abstract] [Full Text] [PDF]

				R. L. Boguslavsky, C. L. Stewart, and H. J. Worman Nuclear lamin A inhibits adipocyte differentiation: implications for Dunnigan-type familial partial lipodystrophy Hum. Mol. Genet., February 15, 2006; 15(4): 653 - 663. [Abstract] [Full Text] [PDF]

				M. Crisp, Q. Liu, K. Roux, J.B. Rattner, C. Shanahan, B. Burke, P. D. Stahl, and D. Hodzic Coupling of the nucleus and cytoplasm: role of the LINC complex J. Cell Biol., January 3, 2006; 172(1): 41 - 53. [Abstract] [Full Text] [PDF]

				N. M.G.M. Appels, J. H. Beijnen, and J. H.M. Schellens Development of Farnesyl Transferase Inhibitors: A Review Oncologist, September 1, 2005; 10(8): 565 - 578. [Abstract] [Full Text] [PDF]

				C. L. Navarro, J. Cadinanos, A. D. Sandre-Giovannoli, R. Bernard, S. Courrier, I. Boccaccio, A. Boyer, W. J. Kleijer, A. Wagner, F. Giuliano, et al. Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors Hum. Mol. Genet., June 1, 2005; 14(11): 1503 - 1513. [Abstract] [Full Text] [PDF]

				D. Ferguson, L. E. Rodriguez, J. P. Palma, M. Refici, K. Jarvis, J. O'Connor, G. M. Sullivan, D. Frost, K. Marsh, J. Bauch, et al. Antitumor Activity of Orally Bioavailable Farnesyltransferase Inhibitor, ABT-100, Is Mediated by Antiproliferative, Proapoptotic, and Antiangiogenic Effects in Xenograft Models Clin. Cancer Res., April 15, 2005; 11(8): 3045 - 3054. [Abstract] [Full Text] [PDF]

				J. Gruber, T. Lampe, M. Osborn, and K. Weber RNAi of FACE1 protease results in growth inhibition of human cells expressing lamin A: implications for Hutchinson-Gilford progeria syndrome J. Cell Sci., February 15, 2005; 118(4): 689 - 696. [Abstract] [Full Text] [PDF]

				K Fukuchi, T Katsuya, K Sugimoto, M Kuremura, H D Kim, L Li, and T Ogihara LMNA mutation in a 45 year old Japanese subject with Hutchinson-Gilford progeria syndrome J. Med. Genet., May 1, 2004; 41(5): e67 - e67. [Full Text] [PDF]

				J. Malecki, J. Wesche, C. S. Skjerpen, A. Wiedlocha, and S. Olsnes Translocation of FGF-1 and FGF-2 across Vesicular Membranes Occurs during G1-Phase by a Common Mechanism Mol. Biol. Cell, February 1, 2004; 15(2): 801 - 814. [Abstract] [Full Text] [PDF]

				A. K. Agarwal, J.-P. Fryns, R. J. Auchus, and A. Garg Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia Hum. Mol. Genet., August 15, 2003; 12(16): 1995 - 2001. [Abstract] [Full Text] [PDF]

				A. A. Adjei, G. A. Croghan, C. Erlichman, R. S. Marks, J. M. Reid, J. A. Sloan, H. C. Pitot, S. R. Alberts, R. M. Goldberg, L. J. Hanson, et al. A Phase I Trial of the Farnesyl Protein Transferase Inhibitor R115777 in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer Clin. Cancer Res., July 1, 2003; 9(7): 2520 - 2526. [Abstract] [Full Text] [PDF]

				S. Olsnes, O. Klingenberg, and A. Wiedlocha Transport of Exogenous Growth Factors and Cytokines to the Cytosol and to the Nucleus Physiol Rev, January 1, 2003; 83(1): 163 - 182. [Abstract] [Full Text] [PDF]

				T. Mann, E. Gaskins, and C. Beckers Proteolytic Processing of TgIMC1 during Maturation of the Membrane Skeleton of Toxoplasma gondii J. Biol. Chem., October 18, 2002; 277(43): 41240 - 41246. [Abstract] [Full Text] [PDF]

				C. Ostlund, G. Bonne, K. Schwartz, and H. J. Worman Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy J. Cell Sci., March 14, 2002; 114(24): 4435 - 4445. [Abstract] [Full Text] [PDF]

				W. H. Raharjo, P. Enarson, T. Sullivan, C. L. Stewart, and B. Burke Nuclear envelope defects associated with LMNA mutations cause dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy J. Cell Sci., March 14, 2002; 114(24): 4447 - 4457. [Abstract] [Full Text] [PDF]

				C. Vigouroux, M. Auclair, E. Dubosclard, M. Pouchelet, J. Capeau, J.-C. Courvalin, and B. Buendia Nuclear envelope disorganization in fibroblasts from lipodystrophic patients with heterozygous R482Q/W mutations in the lamin A/C gene J. Cell Sci., March 14, 2002; 114(24): 4459 - 4468. [Abstract] [Full Text] [PDF]

				A. A. Adjei Blocking Oncogenic Ras Signaling for Cancer Therapy J Natl Cancer Inst, July 18, 2001; 93(14): 1062 - 1074. [Abstract] [Full Text] [PDF]

				A. A. Adjei, J. N. Davis, L. M. Bruzek, C. Erlichman, and S. H. Kaufmann Synergy of the Protein Farnesyltransferase Inhibitor SCH66336 and Cisplatin in Human Cancer Cell Lines Clin. Cancer Res., May 1, 2001; 7(5): 1438 - 1445. [Abstract] [Full Text]

				C. K. L. Too, N. Vickaryous, R. T. M. Boudreau, and S. M. Sangster Identification and Nuclear Localization of a Novel Prolactin and Cytokine-Responsive Carboxypeptidase D Endocrinology, March 1, 2001; 142(3): 1357 - 1367. [Abstract] [Full Text] [PDF]

				O. Klingenberg, A. Wiedlocha, L. Citores, and S. Olsnes Requirement of Phosphatidylinositol 3-Kinase Activity for Translocation of Exogenous aFGF to the Cytosol and Nucleus J. Biol. Chem., April 21, 2000; 275(16): 11972 - 11980. [Abstract] [Full Text] [PDF]

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				O Klingenberg, A Wiedlocha, A Rapak, D Khnykin, L Citores, and S Olsnes Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus J. Cell Sci., January 5, 2000; 113(10): 1827 - 1838. [Abstract] [PDF]