A Rab4-like GTPase in Dictyostelium discoideum colocalizes with V-H(+)-ATPases in reticular membranes of the contractile vacuole complex and in lysosomes

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Aubry, L., Klein, G., Martiel, J. and Satre, M (1993). Kinetics of endosomal pH evolution in Dictyostelium discoideum amoebae. J. Cell Sci 105, 861-866.[Abstract]

Bourne, H. R., Sanders, D. A. and McCormick, F (1990). The GTPase superfamily: a conserved switch for diverse cell functions. Nature 348, 125-132.[Medline]

Bourne, H. R., Sanders, D. A. and McCormick, F (1991). The GTPase superfamily: conserved structure and molecular mechanism. Nature 349, 117-127.[Medline]

Bucci, C., Parton, R., Mather, I., Stunnenberg, H., Simons, K., Hoflack, B. and Zerial, M (1992). The GTPase Rab 5 functions as a regulatory factor in the early endocytic pathway. Cell 70, 715-728.[Medline]

Bush, J. and Cardelli, J (1989). Processing, transport, and secretion of acid phosphatase in Dictyostelium discoideum. J. Biol. Chem 264, 7630-7636.[Abstract/Free Full Text]

Bush, J. and Cardelli, J (1993). Molecular cloning and DNA sequence of a Dictyostelium cDNA encoding a Ran/TC4 related GTP binding protein belonging to the ras superfamily. Nucl. Acids Res 21, 1675-.[Free Full Text]

Bush, J., Franek, K. and Cardelli, J (1993). Cloning and characterization of seven novel Dictyostelium discoideum rac-related genes belonging to the rho family of GTPases. Gene 136, 61-68.[Medline]

Bush, J., Franek, K., Daniel, J., Speigelman, G., Weeks, G. and Cardelli, J. A (1993). Cloning and characterization of five novel Dictyostelium discoideum rab-related genes. Gene 136, 55-60.[Medline]

Cardelli, J. A., Golumbeski, G. S. and Dimond, R. L (1986). Lysosomal enzymes in Dictyostelium discoideum are transported at distinctly different rates. J. Cell Biol 102, 1264-1270.[Abstract/Free Full Text]

Cardelli, J. A., Richardson, J. M. and Miears, D (1989). Role of acidic intracellular compartments in the biosynthesis of Dictyostelium lysosomal enzymes: the weak bases ammonium chloride and chloroquine differentially affect proteolytic processing and sorting. J. Biol. Chem 264, 3454-3463.[Abstract/Free Full Text]

Cardelli, J. A., Bush, J. M and Freeze, H. H (1990). Sulfate on N-linked oligosaccharides affect secretion but is not essential for the transport, proteolytic processing, and sorting of lysosomal enzymes in Dictyostelium discoideum. J. Biol. Chem 265, 8847-8853.[Abstract/Free Full Text]

Cardelli, J. A., Schatzle, J., Bush, J. M., Richardson, J. M., Ebert, D. L. and Freeze, H. H (1990). Biochemical and genetic analysis of the biosynthesis, sorting and secretion of Dictyostelium lysosomal enzymes. Dev. Genet 11, 454-462.[Medline]

Chavrier, P., Parton, R. G., Hauri, H. P., Simons, K. and Zerial, M (1990). Localization of low molecular weight GTP-binding proteins to exocytic and endocytic compartments. Cell 62, 317-329.[Medline]

Ebert, D. L., Freeze, H. H., Richardson, J. M., Dimond, R. L. and Cardelli, J. A (1989). A Dictyostelium discodieum mutant that missorts andoversecretes lysosomal enzyme precursors is defective in endocytosis. J. Cell Biol 109, 1445-1456.[Abstract/Free Full Text]

Daniels, J., Bush, J., Cardelli, J., Spiegelman, G. and Weeks, G (1993). Characterization of two novel ras genes that are maximally expressed during aggregation of Dictyostelium discoideum. Oncogene 9, 501-509.

Fok, A., Clarke, M., Ma, L. and Allen, R (1994). Vacuolar H+-ATPase of Dictyostelium discoideum : a monoclonal antibody study. J. Cell Sci 106, 1103-1113.[Abstract]

Free, S. and Loomis, W (1974). Isolations of mutations in Dictyostelium discoideum affecting-mannosidase. Biochimie 56, 1525-1528.[Medline]

Freeze, H. H (1986). Modifications of lysosomal enzymes in Dictyostelium discoideum. Mol. Cell. Biochem 72, 47-65.[Medline]

Goud, B. and McCaffrey, M (1991). Small GTP-binding proteins and their role in transport. Curr. Opin. Cell Biol 3, 626-633.[Medline]

Heuser, J.. Zhu, Q. and Clarke, M (1993). Proton pumps populate the contractile vacuoles of Dictyostelium discoideum. J. Cell Biol 121, 1311-1327.[Abstract/Free Full Text]

Lombardi, D., Soldati, T., Riederer, N., Goda, Y., Zerial, M. and Pfeffer, S (1993). Rab9 functions in transport between late endosomes and the trans Golgi network. EMBO J 12, 677-682.[Medline]

Mierendorf, R. C., Cardelli, J. A. and Dimond, R. L (1985). Pathways involved in targeting and secretion of a lysosomal enzyme in Dictyostelium discoideum. J. Cell Biol 100, 1777-1787.[Abstract/Free Full Text]

Nolta, K. V., Padh, H. and Steck, T (1991). Acidosomes from Dictyostelium: initial biochemical characterization. J. Biol. Chem 266, 18318-18323.[Abstract/Free Full Text]

Nolta, K. V., Padh, H. and Steck, T. L (1993). An immunochemical analysis of the vacuolar proton pump in Dictyostelium discoideum. J. Cell Sci 105, 849-859.[Abstract]

Nolta, K. V. and Steck, T. L (1994). Isolation and initial characterization of the bipartite contractile vacuole complex from Dictyostelium discoideum. J. Biol. Chem 269, 2225-2233.[Abstract/Free Full Text]

O'Halloran, T. J. and Anderson, R. G (1992). Clathrin heavy chain is required for pinocytosis, the presence of large vacuoles, and development in Dictyostelium. J. Cell Biol 118, 1371-1377.[Abstract/Free Full Text]

Padh, H., Lavasa, M. and Steck, T. L (1991). Endosomes are acidified by association with discrete proton-pumping vacuoles in Dictyostelium. J. Biol. Chem 266, 5514-5520.[Abstract/Free Full Text]

Padh, H., Lavasa, M. and Steck, T. L (1991). Reconstitution of the association of endocytic vacuoles and acidosomes from Dictyostelium. J. Biol. Chem 266, 12123-12126.[Abstract/Free Full Text]

Padh, H., Ha, J., Lavasa, M. and Steck, T. L (1993). A post-lysosomal compartment in Dictyostelium discoideum. J. Biol. Chem 268, 6742-6747.[Abstract/Free Full Text]

Pryer, N. K., Wuestehube, L. J. and Schekman, R (1992). Vesicle mediated protein sorting. Annu. Rev. Biochem 61, 471-516.[Medline]

Reymond, C. D., Gomer, R. H., Mehdy, M. C. and Firtel, R. A (1984). Developmental regulation of a Dictyostelium gene encoding a protein homologous to mammalian Ras protein. Cell 39, 141-148.[Medline]

Richardson, J. R., Woychik, N. A., Ebert, D. L., Dimond, R. L. and Cardelli, J. A (1988). Inhibition of early but not late proteolytic processing events induces the missorting and oversecretion of precursor forms of lysosomal enzymes in Dictysotelium discoideum. J. Cell Biol 107, 2097-2107.[Abstract/Free Full Text]

Robbins, S. M., Williams, J. G., Jermyn, K. A., Spiegelman, G. B. and Weeks, G (1989). Growing and developing Dictyostelium cells express different ras genes. Proc. Nat. Acad. Sci. USA 86, 938-942.[Abstract/Free Full Text]

Robbins, S. M., Suttorp, V. V, Weeks, G. and Spiegelman, G. B (1990). A ras-related gene from the lower eukaryote Dictyostelium that is highly conserved relative to the human rap genes. Nucl. Acids Res 18, 5265-5269.[Abstract/Free Full Text]

Rodriguez-Paris, J. M., Nolta, K. V. and Steck, T. L (1993). Characterization of lysosomes isolated from Dictyostelium discoideum by magnetic fractionation. J. Biol. Chem 268, 9110-9116.[Abstract/Free Full Text]

Rothman, J. and Orci, L (1992). Molecular dissection of the secretory pathway. Nature 355, 409-415.[Medline]

Saxe, S. and Kimmel, A. R (1990). SAS1 and SAS2, GTP-binding protein genes in Dictyostelium discoideum with sequence similarities to essential genes in Saccharomyces cerevisiae. Mol. Cell. Biol 10, 2367-2378.[Abstract/Free Full Text]

Schatzle, J., Rathi, A., Clarke, M. and Cardelli, J (1991). Developmental regulation of the-mannosidase gene in Dictyostelium: control is at the level of transcription and is affected by cell density. Mol. Cell. Biol 11, 3339-3347.[Abstract/Free Full Text]

Schatzle, J. Bush, J. and Cardelli, J (1992). Molecular cloning and characterization of the structural gene coding for the developmentally regulated lysosomal enzyme-mannosidase in Dictyostelium discoideum. J. Biol. Chem 252, 4000-4007.

Tisdale, E. J., Bourne, J. R., Khosravi-far, R., Der, C. J. and Balch, W. E (1992). GTP binding mutants of Rab1 and Rab2 are potent inhibitors of vesicular transport from the ER to the Golgi complex. J. Cell Biol 119, 749-761.[Abstract/Free Full Text]

Valencia, A., Chardin, P., Wittinghofer, A. and Sander, C (1991). The Ras protein family: evolutionary tree and role of conserved amino acids. Biochemistry 30, 4637-4648.[Medline]

van der Sluijs, P., Hull, M., Zahraoui, A., Tavitian, A., Goud, B. and Mellman, I (1991). The small GTP binding protein Rab4 is associated with early endosomes. Proc. Nat. Acad. Sci. USA 88, 6313-6317.[Abstract/Free Full Text]

van der Sluijs, P., Hull, M., Webster, P., Male, P., Goud, B. and Mellman, I (1992). The small GTP-binding protein Rab4 controls an early sorting event on the endocytic pathway. Cell 70, 729-740.[Medline]

Wichmann, H., Hengst, L and Gallwitz, D (1992). Endocytosis in yeast: evidence for the involvement of a small GTP binding protein (Ypt7p). Cell 71, 1131-1142.[Medline]

Wood, L. and Kaplan, A (1985). Transit of-mannosidase during its maturation in Dictyostelium discoideum. J. Cell Biol 101, 2063-2069.[Abstract/Free Full Text]

Zahraoui, A., Touchot, N., Chardin, P. and Tavitian, A (1989). The human rab genes encode a family of GTP-binding proteins related to yeast Ypt1 and Sec4 products involved in secretion. J. Biol. Chem 264, 12394-12401.[Abstract/Free Full Text]

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				C. K. Damer, M. Bayeva, P. S. Kim, L. K. Ho, E. S. Eberhardt, C. I. Socec, J. S. Lee, E. A. Bruce, A. E. Goldman-Yassen, and L. C. Naliboff Copine A Is Required for Cytokinesis, Contractile Vacuole Function, and Development in Dictyostelium Eukaryot. Cell, March 1, 2007; 6(3): 430 - 442. [Abstract] [Full Text] [PDF]

				B. Becker and A. Hickisch Inhibition of Contractile Vacuole Function by Brefeldin A Plant Cell Physiol., January 15, 2005; 46(1): 201 - 212. [Abstract] [Full Text] [PDF]

				K. Ehrenman, G. Yang, W.-P. Hong, T. Gao, W. Jang, D. A. Brock, R. D. Hatton, J. D. Shoemaker, and R. H. Gomer Disruption of Aldehyde Reductase Increases Group Size in Dictyostelium J. Biol. Chem., January 9, 2004; 279(2): 837 - 847. [Abstract] [Full Text] [PDF]

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				E. Harris and J. Cardelli RabD, a Dictyostelium Rab14-related GTPase, regulates phagocytosis and homotypic phagosome and lysosome fusion J. Cell Sci., September 15, 2002; 115(18): 3703 - 3713. [Abstract] [Full Text] [PDF]

				E. Harris, K. Yoshida, J. Cardelli, and J. Bush Rab11-like GTPase associates with and regulates the structure and function of the contractile vacuole system in Dictyostelium J. Cell Sci., March 10, 2002; 114(16): 3035 - 3045. [Abstract] [Full Text] [PDF]

				E. Harris, N. Wang, W.-l Wu, A. Weatherford, A. De Lozanne, and J. Cardelli Dictyostelium LvsB Mutants Model the Lysosomal Defects Associated with Chediak-Higashi Syndrome Mol. Biol. Cell, February 1, 2002; 13(2): 656 - 669. [Abstract] [Full Text] [PDF]

				T. Liu, C. Mirschberger, L. Chooback, Q. Arana, Z. Dal Sacco, H. MacWilliams, and M. Clarke Altered expression of the 100 kDa subunit of the Dictyostelium vacuolar proton pump impairs enzyme assembly, endocytic function and cytosolic pH regulation J. Cell Sci., January 5, 2002; 115(9): 1907 - 1918. [Abstract] [Full Text] [PDF]

				D Gabriel, U Hacker, J Kohler, A Muller-Taubenberger, J. Schwartz, M Westphal, and G Gerisch The contractile vacuole network of Dictyostelium as a distinct organelle: its dynamics visualized by a GFP marker protein J. Cell Sci., January 11, 1999; 112(22): 3995 - 4005. [Abstract] [PDF]

				N Jenne, R Rauchenberger, U Hacker, T Kast, and M Maniak Targeted gene disruption reveals a role for vacuolin B in the late endocytic pathway and exocytosis J. Cell Sci., January 1, 1998; 111(1): 61 - 70. [Abstract] [PDF]

				G. Buczynski, B. Grove, A. Nomura, M. Kleve, J. Bush, R. A. Firtel, and J. Cardelli Inactivation of Two Dictyostelium discoideum Genes, DdPIK1 and DdPIK2, Encoding Proteins Related to Mammalian Phosphatidylinositide 3-kinases, Results in Defects in Endocytosis, Lysosome to Postlysosome Transport, and Actin Cytoskeleton Organization J. Cell Biol., March 24, 1997; 136(6): 1271 - 1286. [Abstract] [Full Text] [PDF]

				L. A. Temesvari, J. M. Bush, M. D. Peterson, K. D. Novak, M. A. Titus, and J. A. Cardelli Examination of the endosomal and lysosomal pathways in Dictyostelium discoideum myosin I mutants J. Cell Sci., March 1, 1996; 109(3): 663 - 673. [Abstract] [PDF]

				L. Temesvari, J. Rodriguez-Paris, J. Bush, L Zhang, and J. Cardelli Involvement of the vacuolar proton-translocating ATPase in multiple steps of the endo-lysosomal system and in the contractile vacuole system of Dictyostelium discoideum J. Cell Sci., January 6, 1996; 109(6): 1479 - 1495. [Abstract] [PDF]

				T Liu and M Clarke The vacuolar proton pump of Dictyostelium discoideum: molecular cloning and analysis of the 100 kDa subunit J. Cell Sci., January 5, 1996; 109(5): 1041 - 1051. [Abstract] [PDF]

				M Ishida, A. Fok, M. Aihara, and R. Allen Hyperosmotic stress leads to reversible dissociation of the proton pump-bearing tubules from the contractile vacuole complex in Paramecium J. Cell Sci., January 1, 1996; 109(1): 229 - 237. [Abstract] [PDF]