Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A. Evidence that this protein is required for uptake and degradation of multiple ligands

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				V. Stepanova, T. Lebedeva, A. Kuo, S. Yarovoi, S. Tkachuk, S. Zaitsev, K. Bdeir, I. Dumler, M. S. Marks, Y. Parfyonova, et al. Nuclear translocation of urokinase-type plasminogen activator Blood, July 1, 2008; 112(1): 100 - 110. [Abstract] [Full Text] [PDF]

				A. Gaultier, S. Arandjelovic, S. Niessen, C. D. Overton, M. F. Linton, S. Fazio, W. M. Campana, B. F. Cravatt III, and S. L. Gonias Regulation of tumor necrosis factor receptor-1 and the IKK-NF-{kappa}B pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor Blood, June 1, 2008; 111(11): 5316 - 5325. [Abstract] [Full Text] [PDF]

				A. W. Orr, C. E. Pedraza, M. A. Pallero, C. A. Elzie, S. Goicoechea, D. K. Strickland, and J. E. Murphy-Ullrich Low density lipoprotein receptor-related protein is a calreticulin coreceptor that signals focal adhesion disassembly J. Cell Biol., June 23, 2003; 161(6): 1179 - 1189. [Abstract] [Full Text] [PDF]

				L. Snyers, H. Zwickl, and D. Blaas Human Rhinovirus Type 2 Is Internalized by Clathrin-Mediated Endocytosis J. Virol., May 1, 2003; 77(9): 5360 - 5369. [Abstract] [Full Text] [PDF]

				S. Sugii, P. C. Reid, N. Ohgami, Y. Shimada, R. A. Maue, H. Ninomiya, Y. Ohno-Iwashita, and T.-Y. Chang Biotinylated {theta}-toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells J. Lipid Res., May 1, 2003; 44(5): 1033 - 1041. [Abstract] [Full Text] [PDF]

				P. C. Reid, S. Sugii, and T.-Y. Chang Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann-Pick type C1 mice J. Lipid Res., May 1, 2003; 44(5): 1010 - 1019. [Abstract] [Full Text] [PDF]

				P. May, Y. K. Reddy, and J. Herz Proteolytic Processing of Low Density Lipoprotein Receptor-related Protein Mediates Regulated Release of Its Intracellular Domain J. Biol. Chem., May 17, 2002; 277(21): 18736 - 18743. [Abstract] [Full Text] [PDF]

				A. M. Salicioni, K. S. Mizelle, E. Loukinova, I. Mikhailenko, D. K. Strickland, and S. L. Gonias The Low Density Lipoprotein Receptor-related Protein Mediates Fibronectin Catabolism and Inhibits Fibronectin Accumulation on Cell Surfaces J. Biol. Chem., May 3, 2002; 277(18): 16160 - 16166. [Abstract] [Full Text] [PDF]

				S. Cases, S. J. Stone, P. Zhou, E. Yen, B. Tow, K. D. Lardizabal, T. Voelker, and R. V. Farese Jr. Cloning of DGAT2, a Second Mammalian Diacylglycerol Acyltransferase, and Related Family Members J. Biol. Chem., October 12, 2001; 276(42): 38870 - 38876. [Abstract] [Full Text] [PDF]

				P. G. Ulery, J. Beers, I. Mikhailenko, R. E. Tanzi, G. W. Rebeck, B. T. Hyman, and D. K. Strickland Modulation of beta -Amyloid Precursor Protein Processing by the Low Density Lipoprotein Receptor-related Protein (LRP). EVIDENCE THAT LRP CONTRIBUTES TO THE PATHOGENESIS OF ALZHEIMER'S DISEASE J. Biol. Chem., March 15, 2000; 275(10): 7410 - 7415. [Abstract] [Full Text] [PDF]

				D. J. Webb, D. H.�D. Nguyen, M. Sankovic, and S. L. Gonias The Very Low Density Lipoprotein Receptor Regulates Urokinase Receptor Catabolism and Breast Cancer Cell Motility in Vitro J. Biol. Chem., March 12, 1999; 274(11): 7412 - 7420. [Abstract] [Full Text] [PDF]

				M. Trommsdorff, J.-P. Borg, B. Margolis, and J. Herz Interaction of Cytosolic Adaptor Proteins with Neuronal Apolipoprotein E Receptors and the Amyloid Precursor Protein J. Biol. Chem., December 11, 1998; 273(50): 33556 - 33560. [Abstract] [Full Text] [PDF]

				Z.-S. Ji, R. E. Pitas, and R. W. Mahley Differential Cellular Accumulation/Retention of Apolipoprotein E Mediated by Cell Surface Heparan Sulfate Proteoglycans. APOLIPOPROTEINS E3 AND E2 GREATER THAN E4 J. Biol. Chem., May 29, 1998; 273(22): 13452 - 13460. [Abstract] [Full Text] [PDF]

				R. K. Avramoglu, J. Nimpf, R. S. McLeod, K. W.�S. Ko, Y. Wang, D. FitzGerald, and Z. Yao Functional Expression of the Chicken Low Density Lipoprotein Receptor-related Protein in a Mutant Chinese Hamster Ovary Cell Line Restores Toxicity of Pseudomonas Exotoxin A and Degradation of alpha 2-Macroglobulin J. Biol. Chem., March 13, 1998; 273(11): 6057 - 6065. [Abstract] [Full Text] [PDF]

				S. Stefansson, S. Muhammad, X.-F. Cheng, F. D. Battey, D. K. Strickland, and D. A. Lawrence Plasminogen Activator Inhibitor-1 Contains a Cryptic High Affinity Binding Site for the Low Density Lipoprotein Receptor-related Protein J. Biol. Chem., March 13, 1998; 273(11): 6358 - 6366. [Abstract] [Full Text] [PDF]

				M. F. Knauer, S. J. Kridel, S. B. Hawley, and D. J. Knauer The Efficient Catabolism of Thrombin-Protease Nexin 1�Complexes Is a Synergistic Mechanism That Requires Both the LDL Receptor-related Protein and Cell Surface Heparins J. Biol. Chem., November 14, 1997; 272(46): 29039 - 29045. [Abstract] [Full Text] [PDF]

				G. Ho, G. J. Broze Jr., and A. L. Schwartz Role of Heparan Sulfate Proteoglycans in the Uptake and Degradation of Tissue Factor Pathway Inhibitor-Coagulation Factor Xa Complexes J. Biol. Chem., July 4, 1997; 272(27): 16838 - 16844. [Abstract] [Full Text] [PDF]

				A. M. Weaver, I. M. Hussaini, A. Mazar, J. Henkin, and S. L. Gonias Embryonic Fibroblasts That Are Genetically Deficient in Low Density Lipoprotein Receptor-related Protein Demonstrate Increased Activity of the Urokinase Receptor System and Accelerated Migration on Vitronectin J. Biol. Chem., May 30, 1997; 272(22): 14372 - 14379. [Abstract] [Full Text] [PDF]

				M. F. Knauer, S. B. Hawley, and D. J. Knauer Identification of a Binding Site in Protease Nexin I (PN1) Required for the Receptor Mediated Internalization of PN1-Thrombin Complexes J. Biol. Chem., May 9, 1997; 272(19): 12261 - 12264. [Abstract] [Full Text] [PDF]

				I. Mikhailenko, D. Krylov, K. M. Argraves, D. D. Roberts, G. Liau, and D. K. Strickland Cellular Internalization and Degradation of Thrombospondin-1 Is Mediated by the Amino-terminal Heparin Binding Domain (HBD). HIGH AFFINITY INTERACTION OF DIMERIC HBD WITH THE LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN J. Biol. Chem., March 7, 1997; 272(10): 6784 - 6791. [Abstract] [Full Text] [PDF]

				A. M. Fagan, G. Bu, Y. Sun, A. Daugherty, and D. M. Holtzman Apolipoprotein E-containing High Density Lipoprotein Promotes Neurite Outgrowth and Is a Ligand for the Low Density Lipoprotein Receptor-related Protein J. Biol. Chem., November 22, 1996; 271(47): 30121 - 30125. [Abstract] [Full Text] [PDF]

				I. Warshawsky, J. Herz, G. J. Broze Jr., and A. L. Schwartz The Low Density Lipoprotein Receptor-related Protein Can Function Independently from Heparan Sulfate Proteoglycans in Tissue Factor Pathway Inhibitor Endocytosis J. Biol. Chem., October 18, 1996; 271(42): 25873 - 25879. [Abstract] [Full Text] [PDF]

				J. D. Medh, S. L. Bowen, G. L. Fry, S. Ruben, M. Andracki, I. Inoue, J.-M. Lalouel, D. K. Strickland, and D. A. Chappell Lipoprotein Lipase Binds to Low Density Lipoprotein Receptors and Induces Receptor-mediated Catabolism of Very Low Density Lipoproteins in Vitro J. Biol. Chem., July 19, 1996; 271(29): 17073 - 17080. [Abstract] [Full Text] [PDF]

				G. Ho, J. R. Toomey, G. J. Broze Jr., and A. L. Schwartz Receptor-mediated Endocytosis of Coagulation Factor Xa Requires Cell Surface-bound Tissue Factor Pathway Inhibitor J. Biol. Chem., April 19, 1996; 271(16): 9497 - 9502. [Abstract] [Full Text] [PDF]

				A. G. Zdanovsky, M. V. Zdanovskaia, D. Strickland, and D. J. FitzGerald Ligand-toxin Hybrids Directed to the alpha(2)-Macroglobulin Receptor/Low Density Lipoprotein Receptor-related Protein Exhibit Lower Toxicity than Native Pseudomonas Exotoxin J. Biol. Chem., March 15, 1996; 271(11): 6122 - 6128. [Abstract] [Full Text] [PDF]

				M. Z. Kounnas, F. C. Church, W. S. Argraves, and D. K. Strickland Cellular Internalization and Degradation of Antithrombin III-Thrombin, Heparin Cofactor II-Thrombin, and alpha(1)-Antitrypsin-Trypsin Complexes Is Mediated by the Low Density Lipoprotein Receptor-related Protein J. Biol. Chem., March 15, 1996; 271(11): 6523 - 6529. [Abstract] [Full Text] [PDF]

				K. M. Argraves, F. D. Battey, C. D. MacCalman, K. R. McCrae, M. G�fvels, K. F. Kozarsky, D. A. Chappell, J. F. Strauss , III, and D. K. Strickland The Very Low Density Lipoprotein Receptor Mediates the Cellular Catabolism of Lipoprotein Lipase and Urokinase-Plasminogen Activator Inhibitor Type I Complexes J. Biol. Chem., November 3, 1995; 270(44): 26550 - 26557. [Abstract] [Full Text] [PDF]

				T. Hiesberger, M. Hermann, L. Jacobsen, S. Novak, R. A. Hodits, H. Bujo, M. Meilinger, M. Httinger, W. J. Schneider, and J. Nimpf The Chicken Oocyte Receptor for Yolk Precursors as a Model for Studying the Action of Receptor-associated Protein and Lactoferrin J. Biol. Chem., August 4, 1995; 270(31): 18219 - 18226. [Abstract] [Full Text] [PDF]

				M. Z. Kounnas, D. A. Chappell, H. Wong, W. S. Argraves, and D. K. Strickland The Cellular Internalization and Degradation of Hepatic Lipase Is Mediated by Low Density Lipoprotein Receptor-related Protein and Requires Cell Surface Proteoglycans J. Biol. Chem., April 21, 1995; 270(16): 9307 - 9312. [Abstract] [Full Text] [PDF]

				W. Poller, T. E. Willnow, J. Hilpert, and J. Herz Differential Recognition of alpha(1)-Antitrypsin-Elastase and alpha(1)-Antichymotrypsin-Cathepsin G Complexes by the Low Density Lipoprotein Receptor-related Protein J. Biol. Chem., February 10, 1995; 270(6): 2841 - 2845. [Abstract] [Full Text] [PDF]