Sense and antisense transfection analysis of tau function: tau influences net microtubule assembly, neurite outgrowth and neuritic stability

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Esmaeli-Azad, B.
	Articles by Feinstein, S. C.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Esmaeli-Azad, B.
	Articles by Feinstein, S. C.

Aletta, J. M. and Greene, L. A (1987). Sequential phosphorylation of chartin microtubule-associated proteins is regulated by the presence of microtubules. J. Cell Biol 105, 277-290.[Abstract/Free Full Text]

Basi, G. S., Jacobson, R. D., Virag, I., Schilling, J. and Skene, J. H. P (1987). Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth. Cell 49, 785-791.[Medline]

Binder, L. I., Frankfurter, A. and Rebhun, L. I (1985). The distribution of tau in the mammalian central nervous system. J. Cell Biol 101, 1371-1378.[Abstract/Free Full Text]

Black, M. M. and Greene, L. A (1982). Changes in the colchicine susceptibility of microtubules associated with neurite outgrowth: studies with nerve growth factor responsive PC12 pheochromocytoma cells. J. Cell Biol 95, 379-386.[Abstract/Free Full Text]

Bridgman, P. C. and Dailey, M. E (1989). The organization of myosin and actin in rapid frozen nerve growth cones. J. Cell Biol 108, 95-109.[Abstract/Free Full Text]

Brugg, B. and Matus, A (1988). PC12 cells express juvenile microtubule-associated proteins during nerve growth factor-induced neurite outgrowth. J. Cell Biol 107, 643-650.[Abstract/Free Full Text]

Brugg, B. and Matus, A (1991). Phosphorylation determines the binding of microtubule-associated protein 2 (MAP2) to microtubules in living cells. J. Cell Biol 114, 735-743.[Abstract/Free Full Text]

Caceres, A. and Kosik, K. S (1990). Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons. Nature 343, 461-463.[Medline]

Caceres, A., Potrebic, S. and Kosik K. S (1991). The effect of tau antisense oligonucleotides on neurite formation of cultured cerebellar macroneurons. J. Neurosci 11, 1515-1523.[Abstract]

Caceres, A., Mautino, J. and Kosik, K. S (1992). Suppression of MAP2 in cultured cerebellar macroneurons inhibits minor neurite formation. Neuron 9, 607-618.[Medline]

Cheng, T. P. O. and Reese, T. S (1985). Polarized compartmentalization of organelles in growth cones from developing optic tectum. J. Cell Biol 101, 1473-1480.[Abstract/Free Full Text]

Cleveland, D. W., Hwo, S. Y. and Kirschner, M. W (1977). Purification of tau: a microtubule-associated protein that induces assembly of microtubules from purified tubulin. J. Mol. Biol 116, 207-225.[Medline]

Drechsel, D. N., Hyman, A. A., Cobb, M. H. and Kirschner, M. W (1992). Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol. Biol. Cell 3, 1141-1154.[Abstract]

Drubin, D. G., Feinstein, S. C., Shooter, E. M. and Kirschner, M. W (1985). Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinated induction of microtubule assembly and assembly-promoting factors. J. Cell Biol 101, 1799-1807.[Abstract/Free Full Text]

Drubin, D. G. and Kirschner, M. W (1986). tau function in living cells. J Cell Biol 103, 2739-2746.[Abstract/Free Full Text]

Esmaeli-Azad, B. and Feinstein, S. C (1991). A general radiochemical-colorimetric procedure for quantitation of immunoblots. Anal. Biochem 199, 275-278.[Medline]

Farrell, K. W., Jordan, M. A., Miller, H. P. and Wilson, L (1987). Phase dynamics at microtubule ends: the coexistence of microtubule length changes and treadmilling. J. Cell Biol 104, 1035-1046.[Abstract/Free Full Text]

Greene, L. A. and Tischler, A. S (1976). Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Nat. Acad. Sci. USA 73, 2424-2428.[Abstract/Free Full Text]

Greene, L. A., Liem, R. K. H. and Shelanski, M. L (1983). Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor. J. Cell Biol 96, 76-83.[Abstract/Free Full Text]

Grundke-Iqbal, I., Iqbal, K., Tung, Y. C., Quinland, M,, Wisniewski, H. and Binder, L (1986). Abnormal phosphorylation of the microtubule associated protein tau in Alzheimer cytoskeletal pathology. Proc. Nat. Acad. Sci. USA 83, 4913-4917.[Abstract/Free Full Text]

Gunning, P. W., Leavitt, J., Muscat, G., Ng, S. Y. and Kedes, L (1987). A human bactin expression vector system directs high-level accumulation of antisense transcripts. Proc. Nat. Acad. Sci. USA 84, 4831-4835.[Abstract/Free Full Text]

Hagestedt, T., Lichtenberg, B., Wille, H., Mandelkow, E-M. and Mandelkow, E (1989). tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation. J. Cell Biol 109, 1643-1651.[Abstract/Free Full Text]

Hanemaaijer, R. and Ginzburg, I (1991). Involvement of mature tau isoforms in the stabilization of neurites in PC12 cells. J. Neurosci Res 30, 163-171.[Medline]

Heidemann, S. R., Joshi, H. C., Schechter, A., Fletcher, J. R. and Bothwell. M (1985). Synergistic effects of cyclic AMP and nerve growth factor on neurite outgrowth and microtubule stability of PC 12 cells. J. Cell Biol 100, 916-927.[Abstract/Free Full Text]

Hirokawa, N (1982). Cross-linker system between neurofilaments, microtubules and membraneous organelles in frog axons revealed by the quick-freeze, deep-etching method. J. Cell Biol 94, 129-142.[Abstract/Free Full Text]

Horio, T. and Hotani, H (1986). Visualization of the dynamic instability of individual microtubules by dark field microscopy. Nature 321, 605-657.[Medline]

Ihara, Y., Nukina, N., Miura, R. and Ogawara, M. N (1986). Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease. J. Biochem 99, 1807-1810.

Iqbal, K., Grundke-Iqbal, I,. Smith, A. J., George, L., Tung, Y-C. and Zaidi, T (1989). Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease. Proc. Nat. Acad. Sci. USA 86, 5646-5650.[Abstract/Free Full Text]

Jessell, T. M (1988). Adhesion molecules and the hierarchy of neural development. Neuron 1, 3-13.[Medline]

Kanai, Y., Takemura, R., Takeshi. O., Hiroshi, M., Yasuo, I., Masashi, Y., Masaki, T. and Nobutaka, H (1989). Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA. J. Cell Biol 109, 1173-1184.[Abstract/Free Full Text]

Knops, J., Kosik, K. S., Lee, G., Pardee, J. D., Cohen-Gould, L. and McConlogue, L (1991). Overexpression of tau in a nonneuronal cell induces long cellular processes. J. Cell Biol 114, 725-733.[Abstract/Free Full Text]

Kosik, K. S. and Finch, E. A (1987). MAP2 and tau segregate into dendritic and axonal domains after the elaboration of morphologically distinct neurites: an immunocytochemical study of cultured rat cerebrum. J. Neurosci 7, 3142-3153.[Abstract]

Kosik, K. S., Orecchio, L. D., Binder, L,. Trojanowski, J. Q., Lee, V. M.-Y. and Lee, G (1988). Epitopes that span the tau molecule are shared with paired helical filaments. Neuron 1, 817-825.[Medline]

Kosik, K. S., Orecchio, L. D., Bakalis, S. and Neve, R. L (1989). Developmentally regulated expression of specific tau sequences. Neuron 2, 1389-1397.[Medline]

Letourneau, P. C., Shattuck, T. A. and Ressler, A. H (1987). \324Pull' and \324push' in neurite elongation: observations on the effects of different concentrations of cytochalasin B and taxol. Cell Motil. Cytoskel 8, 193-209.[Medline]

Lewis, S. A., Ivanov, I. E., Lee, G-H. and Cowan, N. J (1989). Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule associated proteins MAP2 and tau. Nature 342, 498-505.[Medline]

Luckenbille-Edds, L., Van Horn, C. and Greene, L. A (1979). Fine structure of initial outgrowth of processes induced in a pheochromocytoma cell line (PC12) by nerve growth factor. J. Neurocytol 8, 493-511.[Medline]

Marsh, L. and Letourneau, P. C (1984). Growth of neurites without filopodial or lamellipodial activity in the presence of cytochalasin B. J. Cell Biol 99, 2041-2047.[Abstract/Free Full Text]

Matus, A (1988). Microtubule associated proteins: their potential role in determining neuronal morphology. Annu. Rev. Neurosci 11, 29-44.[Medline]

Muller, S. R., Sullivan, P. D., Clegg, D. O. and Feinstein, S. C (1990). Efficient transfection and expression of heterologous genes in PC12 cells. DNA Cell Biol 9, 221-229.[Medline]

Nukina, N., Kosik, K. S. and Selkoe, D. J (1987). Recognition of Alzheimerpaired helical filaments by monoclonal neurofilament antibodies is due to crossreaction with tau protein. Proc. Nat. Acad. Sci. USA 84, 3415-3419.[Abstract/Free Full Text]

Pallas, D. and Solomon. F (1982). Cytoplasmic microtubule-associated proteins: phosphorylation at novel sites is correlated with their incorporation into assembled microtubules. Cell 30, 407-414.[Medline]

Peng, I., Binder, L. I. and Black, M. M (1986). Biochemical and immunological analyses of cytoskeletal domains of neurons. J. Cell Biol 102, 252-262.[Abstract/Free Full Text]

Peters, A. and Vaughn, J. E (1967). Microtubules and filaments in the axons and astrocytes of early postnatal rat optic nerves. J. Cell Biol 32, 113-122.[Abstract/Free Full Text]

Sabry, J. H., O'Connor, T. P., Evans, L., Toroian-Raymond. A., Kirschner, M. and Bentley, D (1991). Microtubule behavior during guidance of pioneer neuron growth cones in situ. J. Cell Biol 115, 381-395.[Abstract/Free Full Text]

Schaffner, W. and Weissmann, C (1973). A rapid, sensitive, and specific method for determination of protein in dilute solution. Anal. Biochem 56, 502-514.[Medline]

Schnapp, B. J. and Reese, T. S (1982). Cytoplasmic structure in rapid frozen axons. J. Cell Biol 94, 667-679.[Abstract/Free Full Text]

Selkoe, D. J (1989). Biochemistry of altered brain proteins in Alzheimer's disease. Annu. Rev. Neurosci 12, 463-490.[Medline]

Selkoe, D. J (1991). The molecular pathology of Alzheimer's disease. Neuron 6, 487-498.[Medline]

Shea, T. B., Beermann, M. L., Nixon, R. A. and Fischer, I (1992). Microtubule-associated protein tau is required for axonal neurite elaboration by neuroblastoma cells. J. Neurosci. Res 32, 363-374.[Medline]

Solomon, F., Magendantz, M. and Salzman, A (1979). Identification with cellular microtubules of one of the co-assembling microtubule-associated proteins. Cell 18, 431-438.[Medline]

Steiner, B., Mandelkow, E. M., Biernat, J., Gustke, N., Meyer, H. E., Schmidt, B., Mieskes, G., Soling, H. D., Drechsel, D., Kirschner, M. W., Goedert, M., Mandelkow, E (1991). Phosphorylation of microtubule-associated protein tau: identification of the site for Ca2+-calmodulin dependent kinase and relationship with tau phosphorylation in Alzheimer tangles. EMBO J 9, 3539-3544.[Medline]

Tanaka, E. M. and Kirschner, M. W (1991). Microtubule behavior in the growth cones of living neurons during axon elongation. J. Cell Biol 115, 345-363.[Abstract/Free Full Text]

Tessier-Lavigne, M. and Placzek, M (1991). Target attraction: are developing axons guided by chemotropism?. Trends Neurosci 14, 303-310.[Medline]

Ueda, K., Masliah, E., Saitoh, T., Bakalis, S. L., Scoble, H., Kosik, K. S (1990). Alz-50 recognizes a phosphorylated epitope of tau protein. J. Neurosci 10, 3295-3304.[Abstract]

Weingarten, M. D., Lockwood, A. H., Hwo, S. Y. and Kirschner, M. W (1975). A protein factor essential for microtubule assembly. Proc. Nat. Acad. Sci. USA 72, 1858-1862.[Abstract/Free Full Text]

Wood, J. G., Mirra, S. S., Pollock, N. J. and Binder, L. I (1986). Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau. Proc. Nat. Acad. Sci. USA 83, 4040-4043.[Abstract/Free Full Text]

Yamada, K. M., Spooner, B. S. and Wessels, N. K (1970). Axon growth: roles of microfilaments and microtubules. Proc. Nat. Acad. Sci. USA 66, 1206-1212.[Abstract/Free Full Text]

Yamada, K. M., Spooner, B. S. and Wessels, N. K (1971). Ultrastructure and function of growth cones and axons of cultured nerve cells. J. Cell Biol 49, 614-635.[Abstract/Free Full Text]

Yen, T. J., Gay, D. A., Pachter, J. S. and Cleveland, D. W (1988). Autoregulated changes in stability of polyribosome-bound btubulin mRNAs are specified by the first 13 translated nucleotides. Mol. Cell Biol 8, 1224-1228.[Abstract/Free Full Text]

This article has been cited by other articles:

K. Ikegami, M. Mukai, J.-i. Tsuchida, R. L. Heier, G. R. MacGregor, and M. Setou
TTLL7 Is a Mammalian beta-Tubulin Polyglutamylase Required for Growth of MAP2-positive Neurites
J. Biol. Chem., October 13, 2006; 281(41): 30707 - 30716.
[Abstract] [Full Text] [PDF]

V. Fontaine-Lenoir, B. Chambraud, A. Fellous, S. David, Y. Duchossoy, E.-E. Baulieu, and P. Robel
Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor
PNAS, March 21, 2006; 103(12): 4711 - 4716.
[Abstract] [Full Text] [PDF]

S. F. Levy, A. C. LeBoeuf, M. R. Massie, M. A. Jordan, L. Wilson, and S. C. Feinstein
Three- and Four-repeat Tau Regulate the Dynamic Instability of Two Distinct Microtubule Subpopulations in Qualitatively Different Manners: IMPLICATIONS FOR NEURODEGENERATION
J. Biol. Chem., April 8, 2005; 280(14): 13520 - 13528.
[Abstract] [Full Text] [PDF]

J. L. Ross, C. D. Santangelo, V. Makrides, and D. K. Fygenson
Tau induces cooperative Taxol binding to microtubules
PNAS, August 31, 2004; 101(35): 12910 - 12915.
[Abstract] [Full Text] [PDF]

J. M. Bunker, L. Wilson, M. A. Jordan, and S. C. Feinstein
Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration
Mol. Biol. Cell, June 1, 2004; 15(6): 2720 - 2728.
[Abstract] [Full Text] [PDF]

V. Makrides, T. E. Shen, R. Bhatia, B. L. Smith, J. Thimm, R. Lal, and S. C. Feinstein
Microtubule-dependent Oligomerization of Tau: IMPLICATIONS FOR PHYSIOLOGICAL TAU FUNCTION AND TAUOPATHIES
J. Biol. Chem., August 29, 2003; 278(35): 33298 - 33304.
[Abstract] [Full Text] [PDF]

D. Panda, J. C. Samuel, M. Massie, S. C. Feinstein, and L. Wilson
Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for the onset of neurodegenerative disease
PNAS, August 5, 2003; 100(16): 9548 - 9553.
[Abstract] [Full Text] [PDF]

S. Takahashi, T. Saito, S.-i. Hisanaga, H. C. Pant, and A. B. Kulkarni
Tau Phosphorylation by Cyclin-dependent Kinase 5/p39 during Brain Development Reduces Its Affinity for Microtubules
J. Biol. Chem., March 14, 2003; 278(12): 10506 - 10515.
[Abstract] [Full Text] [PDF]

J. Biernat, Y.-Z. Wu, T. Timm, Q. Zheng-Fischhofer, E. Mandelkow, L. Meijer, and E.-M. Mandelkow
Protein Kinase MARK/PAR-1 Is Required for Neurite Outgrowth and Establishment of Neuronal Polarity
Mol. Biol. Cell, November 1, 2002; 13(11): 4013 - 4028.
[Abstract] [Full Text] [PDF]

A. B. Nixon, G. Grenningloh, and P. J. Casey
The Interaction of RGSZ1 with SCG10 Attenuates the Ability of SCG10 to Promote Microtubule Disassembly
J. Biol. Chem., May 10, 2002; 277(20): 18127 - 18133.
[Abstract] [Full Text] [PDF]

H. Dawson, A Ferreira, M. Eyster, N Ghoshal, L. Binder, and M. Vitek
Inhibition of neuronal maturation in primary hippocampal neurons from &tgr; deficient mice
J. Cell Sci., January 3, 2001; 114(6): 1179 - 1187.
[Abstract] [PDF]

P. K. Davis and G. V. W. Johnson
The Microtubule Binding of Tau and High Molecular Weight Tau in Apoptotic PC12 Cells Is Impaired because of Altered Phosphorylation
J. Biol. Chem., December 10, 1999; 274(50): 35686 - 35692.
[Abstract] [Full Text] [PDF]

K. Spittaels, C. Van den Haute, J. Van Dorpe, K. Bruynseels, K. Vandezande, I. Laenen, H. Geerts, M. Mercken, R. Sciot, A. Van Lommel, et al.
Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein
Am. J. Pathol., December 1, 1999; 155(6): 2153 - 2165.
[Abstract] [Full Text] [PDF]

J. Biernat and E.-M. Mandelkow
The Development of Cell Processes Induced by tau Protein Requires Phosphorylation of Serine 262�and 356�in the Repeat Domain and Is Inhibited by Phosphorylation in the Proline-rich Domains
Mol. Biol. Cell, March 1, 1999; 10(3): 727 - 740.
[Abstract] [Full Text]

H. Nguyen, D Gruber, and J. Bulinski
Microtubule-associated protein 4 (MAP4) regulates assembly, protomer-polymer partitioning and synthesis of tubulin in cultured cells
J. Cell Sci., January 6, 1999; 112(12): 1813 - 1824.
[Abstract] [PDF]

G. Paglini, G. Pigino, P. Kunda, G. Morfini, R. Maccioni, S. Quiroga, A. Ferreira, and A. Caceres
Evidence for the Participation of the Neuron-Specific CDK5 Activator P35 during Laminin-Enhanced Axonal Growth
J. Neurosci., December 1, 1998; 18(23): 9858 - 9869.
[Abstract] [Full Text] [PDF]

I. Tint, T. Slaughter, I. Fischer, and M. M. Black
Acute Inactivation of Tau Has No Effect on Dynamics of Microtubules in Growing Axons of Cultured Sympathetic Neurons
J. Neurosci., November 1, 1998; 18(21): 8660 - 8673.
[Abstract] [Full Text] [PDF]

L. Guillaud, C. Bosc, A. Fourest-Lieuvin, E. Denarier, F. Pirollet, L. Lafanechere, and D. Job
STOP Proteins are Responsible for the High Degree of Microtubule Stabilization Observed in Neuronal Cells
J. Cell Biol., July 13, 1998; 142(1): 167 - 179.
[Abstract] [Full Text] [PDF]

D. B. Zimmer, E. H. Cornwall, P. D. Reynolds, and C. M. Donald
S100A1 Regulates Neurite Organization, Tubulin Levels, and Proliferation in PC12 Cells
J. Biol. Chem., February 20, 1998; 273(8): 4705 - 4711.
[Abstract] [Full Text] [PDF]

G Lee, S. Newman, D. Gard, H Band, and G Panchamoorthy
Tau interacts with src-family non-receptor tyrosine kinases
J. Cell Sci., January 11, 1998; 111(21): 3167 - 3177.
[Abstract] [PDF]

M. Vanier, P Neuville, L Michalik, and J. Launay
Expression of specific tau exons in normal and tumoral pancreatic acinar cells
J. Cell Sci., January 5, 1998; 111(10): 1419 - 1432.
[Abstract] [PDF]

J. Mills, V. Lee, and R. Pittman
Activation of a PP2A-like phosphatase and dephosphorylation of tau protein characterize onset of the execution phase of apoptosis
J. Cell Sci., January 3, 1998; 111(5): 625 - 636.
[Abstract] [PDF]

G. Morfini, S. Quiroga, A. Rosa, K. Kosik, and A. Caceres
Suppression of KIF2 in PC12 Cells Alters the Distribution of a Growth Cone Nonsynaptic Membrane Receptor and Inhibits Neurite Extension
J. Cell Biol., August 11, 1997; 138(3): 657 - 669.
[Abstract] [Full Text] [PDF]

F. Mascotti, A. Caceres, K. H. Pfenninger, and S. Quiroga
Expression and Distribution of IGF-1 Receptors Containing a beta -Subunit Variant (beta gc) in Developing Neurons
J. Neurosci., February 15, 1997; 17(4): 1447 - 1459.
[Abstract] [Full Text] [PDF]

M. Kempf, A. Clement, A. Faissner, G. Lee, and R. Brandt
Tau Binds to the Distal Axon Early in Development of Polarity in a Microtubule- and Microfilament-Dependent Manner
J. Neurosci., September 15, 1996; 16(18): 5583 - 5592.
[Abstract] [Full Text] [PDF]

M. M. Black, T. Slaughter, S. Moshiach, M. Obrocka, and I. Fischer
Tau Is Enriched on Dynamic Microtubules in the Distal Region of Growing Axons
J. Neurosci., June 1, 1996; 16(11): 3601 - 3619.
[Abstract] [Full Text] [PDF]

U Wagner, M Utton, J. Gallo, and C. Miller
Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation
J. Cell Sci., January 6, 1996; 109(6): 1537 - 1543.
[Abstract] [PDF]

M. DiTella, F Feiguin, N Carri, K. Kosik, and A Caceres
MAP-1B/TAU functional redundancy during laminin-enhanced axonal growth
J. Cell Sci., January 2, 1996; 109(2): 467 - 477.
[Abstract] [PDF]

J. Leger, R Brandt, and G Lee
Identification of tau protein regions required for process formation in PC12 cells
J. Cell Sci., January 12, 1994; 107(12): 3403 - 3412.
[Abstract] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Esmaeli-Azad, B.

Articles by Feinstein, S. C.

Search for Related Content

PubMed

PubMed Citation

Articles by Esmaeli-Azad, B.

Articles by Feinstein, S. C.

				V. Fontaine-Lenoir, B. Chambraud, A. Fellous, S. David, Y. Duchossoy, E.-E. Baulieu, and P. Robel Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor PNAS, March 21, 2006; 103(12): 4711 - 4716. [Abstract] [Full Text] [PDF]

				S. F. Levy, A. C. LeBoeuf, M. R. Massie, M. A. Jordan, L. Wilson, and S. C. Feinstein Three- and Four-repeat Tau Regulate the Dynamic Instability of Two Distinct Microtubule Subpopulations in Qualitatively Different Manners: IMPLICATIONS FOR NEURODEGENERATION J. Biol. Chem., April 8, 2005; 280(14): 13520 - 13528. [Abstract] [Full Text] [PDF]

				J. L. Ross, C. D. Santangelo, V. Makrides, and D. K. Fygenson Tau induces cooperative Taxol binding to microtubules PNAS, August 31, 2004; 101(35): 12910 - 12915. [Abstract] [Full Text] [PDF]

				J. M. Bunker, L. Wilson, M. A. Jordan, and S. C. Feinstein Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration Mol. Biol. Cell, June 1, 2004; 15(6): 2720 - 2728. [Abstract] [Full Text] [PDF]

				V. Makrides, T. E. Shen, R. Bhatia, B. L. Smith, J. Thimm, R. Lal, and S. C. Feinstein Microtubule-dependent Oligomerization of Tau: IMPLICATIONS FOR PHYSIOLOGICAL TAU FUNCTION AND TAUOPATHIES J. Biol. Chem., August 29, 2003; 278(35): 33298 - 33304. [Abstract] [Full Text] [PDF]

				D. Panda, J. C. Samuel, M. Massie, S. C. Feinstein, and L. Wilson Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for the onset of neurodegenerative disease PNAS, August 5, 2003; 100(16): 9548 - 9553. [Abstract] [Full Text] [PDF]

				S. Takahashi, T. Saito, S.-i. Hisanaga, H. C. Pant, and A. B. Kulkarni Tau Phosphorylation by Cyclin-dependent Kinase 5/p39 during Brain Development Reduces Its Affinity for Microtubules J. Biol. Chem., March 14, 2003; 278(12): 10506 - 10515. [Abstract] [Full Text] [PDF]

				J. Biernat, Y.-Z. Wu, T. Timm, Q. Zheng-Fischhofer, E. Mandelkow, L. Meijer, and E.-M. Mandelkow Protein Kinase MARK/PAR-1 Is Required for Neurite Outgrowth and Establishment of Neuronal Polarity Mol. Biol. Cell, November 1, 2002; 13(11): 4013 - 4028. [Abstract] [Full Text] [PDF]

				A. B. Nixon, G. Grenningloh, and P. J. Casey The Interaction of RGSZ1 with SCG10 Attenuates the Ability of SCG10 to Promote Microtubule Disassembly J. Biol. Chem., May 10, 2002; 277(20): 18127 - 18133. [Abstract] [Full Text] [PDF]

				H. Dawson, A Ferreira, M. Eyster, N Ghoshal, L. Binder, and M. Vitek Inhibition of neuronal maturation in primary hippocampal neurons from &tgr; deficient mice J. Cell Sci., January 3, 2001; 114(6): 1179 - 1187. [Abstract] [PDF]

				P. K. Davis and G. V. W. Johnson The Microtubule Binding of Tau and High Molecular Weight Tau in Apoptotic PC12 Cells Is Impaired because of Altered Phosphorylation J. Biol. Chem., December 10, 1999; 274(50): 35686 - 35692. [Abstract] [Full Text] [PDF]

				K. Spittaels, C. Van den Haute, J. Van Dorpe, K. Bruynseels, K. Vandezande, I. Laenen, H. Geerts, M. Mercken, R. Sciot, A. Van Lommel, et al. Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein Am. J. Pathol., December 1, 1999; 155(6): 2153 - 2165. [Abstract] [Full Text] [PDF]

				J. Biernat and E.-M. Mandelkow The Development of Cell Processes Induced by tau Protein Requires Phosphorylation of Serine 262�and 356�in the Repeat Domain and Is Inhibited by Phosphorylation in the Proline-rich Domains Mol. Biol. Cell, March 1, 1999; 10(3): 727 - 740. [Abstract] [Full Text]

				H. Nguyen, D Gruber, and J. Bulinski Microtubule-associated protein 4 (MAP4) regulates assembly, protomer-polymer partitioning and synthesis of tubulin in cultured cells J. Cell Sci., January 6, 1999; 112(12): 1813 - 1824. [Abstract] [PDF]

				G. Paglini, G. Pigino, P. Kunda, G. Morfini, R. Maccioni, S. Quiroga, A. Ferreira, and A. Caceres Evidence for the Participation of the Neuron-Specific CDK5 Activator P35 during Laminin-Enhanced Axonal Growth J. Neurosci., December 1, 1998; 18(23): 9858 - 9869. [Abstract] [Full Text] [PDF]

				I. Tint, T. Slaughter, I. Fischer, and M. M. Black Acute Inactivation of Tau Has No Effect on Dynamics of Microtubules in Growing Axons of Cultured Sympathetic Neurons J. Neurosci., November 1, 1998; 18(21): 8660 - 8673. [Abstract] [Full Text] [PDF]

				L. Guillaud, C. Bosc, A. Fourest-Lieuvin, E. Denarier, F. Pirollet, L. Lafanechere, and D. Job STOP Proteins are Responsible for the High Degree of Microtubule Stabilization Observed in Neuronal Cells J. Cell Biol., July 13, 1998; 142(1): 167 - 179. [Abstract] [Full Text] [PDF]

				D. B. Zimmer, E. H. Cornwall, P. D. Reynolds, and C. M. Donald S100A1 Regulates Neurite Organization, Tubulin Levels, and Proliferation in PC12 Cells J. Biol. Chem., February 20, 1998; 273(8): 4705 - 4711. [Abstract] [Full Text] [PDF]

				G Lee, S. Newman, D. Gard, H Band, and G Panchamoorthy Tau interacts with src-family non-receptor tyrosine kinases J. Cell Sci., January 11, 1998; 111(21): 3167 - 3177. [Abstract] [PDF]

				M. Vanier, P Neuville, L Michalik, and J. Launay Expression of specific tau exons in normal and tumoral pancreatic acinar cells J. Cell Sci., January 5, 1998; 111(10): 1419 - 1432. [Abstract] [PDF]

				J. Mills, V. Lee, and R. Pittman Activation of a PP2A-like phosphatase and dephosphorylation of tau protein characterize onset of the execution phase of apoptosis J. Cell Sci., January 3, 1998; 111(5): 625 - 636. [Abstract] [PDF]

				G. Morfini, S. Quiroga, A. Rosa, K. Kosik, and A. Caceres Suppression of KIF2 in PC12 Cells Alters the Distribution of a Growth Cone Nonsynaptic Membrane Receptor and Inhibits Neurite Extension J. Cell Biol., August 11, 1997; 138(3): 657 - 669. [Abstract] [Full Text] [PDF]

				F. Mascotti, A. Caceres, K. H. Pfenninger, and S. Quiroga Expression and Distribution of IGF-1 Receptors Containing a beta -Subunit Variant (beta gc) in Developing Neurons J. Neurosci., February 15, 1997; 17(4): 1447 - 1459. [Abstract] [Full Text] [PDF]

				M. Kempf, A. Clement, A. Faissner, G. Lee, and R. Brandt Tau Binds to the Distal Axon Early in Development of Polarity in a Microtubule- and Microfilament-Dependent Manner J. Neurosci., September 15, 1996; 16(18): 5583 - 5592. [Abstract] [Full Text] [PDF]

				M. M. Black, T. Slaughter, S. Moshiach, M. Obrocka, and I. Fischer Tau Is Enriched on Dynamic Microtubules in the Distal Region of Growing Axons J. Neurosci., June 1, 1996; 16(11): 3601 - 3619. [Abstract] [Full Text] [PDF]

				U Wagner, M Utton, J. Gallo, and C. Miller Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation J. Cell Sci., January 6, 1996; 109(6): 1537 - 1543. [Abstract] [PDF]

				M. DiTella, F Feiguin, N Carri, K. Kosik, and A Caceres MAP-1B/TAU functional redundancy during laminin-enhanced axonal growth J. Cell Sci., January 2, 1996; 109(2): 467 - 477. [Abstract] [PDF]

				J. Leger, R Brandt, and G Lee Identification of tau protein regions required for process formation in PC12 cells J. Cell Sci., January 12, 1994; 107(12): 3403 - 3412. [Abstract] [PDF]