Down regulation of talin alters cell adhesion and the processing of the alpha 5 beta 1 integrin

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Argraves, W. C., Susuki, S., Arai, H., Thompson, K., Pierschbacher, M. D. and Ruoslahti, E (1987). Amino acid sequence of the human fibronectin receptor. J. Cell Biol 105, 1183-1190.[Abstract/Free Full Text]

Balzac, F., Belkin, A. M., Koteliansky, V. E., Balabanov, Y. V., Altruda, F., Silengo, L. and Tarone, G (1993). Expression of functional analysis of a cytoplasmic domain variant of the1 integrin subunit. J. Cell Biol 21, 171-178.

Beckerle, M. C., Burridge, K., DeMartino, G. N. and Croall, D. E (1987). Colocalization of calcium-dependent protease II and one of its substrates at sites of cell adhesion. Cell 51, 569-577.[Medline]

Beckerle, M. C. and Yeh, R. K (1990). Talin role at sites of cell-substratum adhesion. Cell Motil. Cytoskel 16, 7-13.[Medline]

Bertagnolli, M. E., Locke S. J., Hensler, M. E., Bray, P. F. and Beckerle, M. C (1993). Talin distribution and phosphorylation in thrombin-activated platelets. J. Cell Sci 106, 1189-1199.[Abstract]

Bockholt, S. M. and Burridge, K (1993). Cell spreading on extracellular matrix proteins induces tyrosine phosphorylation of tensin. J. Biol. Chem 268, 14565-14567.[Abstract/Free Full Text]

Briesewitz, R., Kern, A. and Marcantonio, E (1993). Ligand-dependent and-independant integrin focal contact localization: the role of thechain cytoplasmic domain. Mol. Biol. Cell 4, 593-604.[Abstract]

Briesewitz, R., Epstein, M. R. and Marcantonio, E (1993). Expression of native and truncated forms of the human interin1 sbunit. J. Biol. Chem 268, 2989-2996.[Abstract/Free Full Text]

Burridge, K., Fath, K., Kelly, T., Nuckolls, G. and Turner, C (1988). Focal adhesion: Transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol 4, 487-525.

Burridge, M. D., Turner, C. E. and Romer, L. H (1992). Tyrosine phosphorylation of paxillin and pp125fak accompanies cell adhesion to extracellular matrix- a role in cytoskeletal assembly. J. Cell Biol 119, 893-903.[Abstract/Free Full Text]

Chen, D., Magnuson, V., Hill, S., Arnaud, C., Steffensen, B. and Klebe, R. J (1992). Regulation of integrin gene expression by substrate adherence. J. Biol. Chem 267, 23502-23506.[Abstract/Free Full Text]

Dejana, E., Colella, S., Conforti, G., Abbadini, M., Gaboli, M. and Marchisio, P.-C (1988). Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells. J. Cell Biol 107, 1215-1223.[Abstract/Free Full Text]

Engvall, E. and Ruoslahti, E (1977). Binding of soluble form of fibroblast surface protein, fibronectin, to collagen. Int. J. Cancer 20, 1-5.[Medline]

Frachet, P., Duperray, A., Delachanal, E. and Marguerie, G (1992). Role of the transmembrane and cytoplasmic domains in the assembly and surface exposure of the platelet integrin GPIIb/IIIa. Biochemistry 31, 2408-2415.[Medline]

Frelinger, III, A. L., Lam, S. C.-T., Plow, E. F., Smith, M. A., Loftus, J. C. and Ginsberg, M. H (1988). Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion. J. Biol. Chem 263, 12397-12402.[Abstract/Free Full Text]

Gilmore, A. P., Jackson, P., Waites, G. T. and Critchley, D. R (1992). Further characterisation of the talin binding site in the cytoskeletal protein vinculin. J. Cell Sci 103, 719-731.[Abstract]

Gough, N. M (1988). Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells. Anal. Biochem 173, 93-95.[Medline]

Heino, J., Ignotz, R. A., Hemler, M. E., Crouse, C. and Massague J (1989). Regulation of cell adhesion receptors by transforming growth factor-. J. Biol. Chem 264, 380-388.[Abstract/Free Full Text]

Hemler, M. E (1990). VLA proteins in the integrin family: structures, functions, and their role on leucocytes. Annu. Rev. Immunol 8, 365-400.[Medline]

Horwitz, A., Duggan, E., Buck, C., Beckerle, M. C. and Burridge, K (1986). Interaction of plasma membrane fibronectin receptor with talin- a transmembrane linkage. Nature 320, 531-533.[Medline]

Hotchin, N. A. and Watt, F. M (1992). Transcriptional and post-transcriptional regulation of1 integrin expression during keratinocyte terminal differentiation. J. Biol. Chem 267, 14852-14858.[Abstract/Free Full Text]

Hynes, R. O (1992). Integrins: Versatility, modulation and signalling in cell adhesion. Cell 69, 11-25.[Medline]

Isberg, R. R. and Leong, J. M (1990). Multiple1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells. Cell 60, 861-871.[Medline]

Luna, E. J. and Hitt, A. L (1992). Cytoskeleton-plasma membrane interactions. Science 258, 955-963.[Abstract/Free Full Text]

Muguruma, M., Matsumura, S. and Fukazawa, T (1990). Direct interaction between talin and actin. Biochem. Biophys. Res. Commun 171, 1217-1223.[Medline]

Nuckolls, G. H., Romer, L. H. and Burridge K (1992). Microinjection of antibodies against talin inhibits the spreading and migration of fibroblasts. J. Cell Sci 102, 723-752.[Abstract/Free Full Text]

Otey, C. A., Pavalko, F. M. and Burridge K (1990). An interaction between-actinin and the 1 integrin subunit in vitro. J. Cell Biol 111, 721-729.[Abstract/Free Full Text]

Rees, D. J. G., Ades, S. E., Singer, S. J. and Hynes, R. O (1990). Sequence and domain structure of talin. Nature 347, 685-689.[Medline]

Rodriguez Fernandez, J. L., Geiger, B., Salomon, D., Sabanay, I., Zoller,M. and Ben-Ze'ev, A (1992). Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA. J. Cell Biol 119, 427-438.[Abstract/Free Full Text]

Rodriguez Fernandez, J. L., Geiger, B., Salomon, D. and Ben-Ze'ev, A (1993). Suppression of vinculin expression by antisense transfection confers changes in cell morphology, and anchorage dependent growth of 3T3 cells. J. Cell Biol 122, 1285-1294.[Abstract/Free Full Text]

Sastry, S. K. and Horwitz, A. F (1993). Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra-and intracellular initiated transmembrane signalling. Curr. Opin. Cell Biol 5, 819-831.[Medline]

Schaller, M. D., Borgman, C. A., Cobb, B. S., Vines, R. R., Reynolds, A. B. and Parsons, J. T (1992). Pp 125 fak, a structurally distinctive protein-tyrosine kinase associated with focal adhesion. Proc. Nat. Acad. Sci. USA 89, 5192-5196.[Abstract/Free Full Text]

Seed, B. and Aruffo, A (1987). Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc. Nat. Acad. Sci. USA 84, 3365-3369.[Abstract/Free Full Text]

Simons, P. C. and Elias, L (1993). The 47kD fragment of talin is a substrate for protein kinase P. Blood 82, 3343-3349.[Abstract/Free Full Text]

Takada, Y. and Puzon, W (1993). Identification of a regulatory region of integrin1 subunit using activating and inhibiting antibodies. J. Biol. Chem 268, 17597-17601.[Abstract/Free Full Text]

Tranqui, L., Soyez, S. and Block, M. R (1992). An in vitro model giving access to adhesion plaques. In Vitro Cell. Dev. Biol 28, 17-23.

Tranqui, L., Usson, Y., Marie, C. and Block, M. R (1993). Adhesion of CHO cells to fibronectin is mediated by functionally and structurally distinct adhesion plaques. J. Cell Sci 106, 377-387.[Abstract]

Tranqui, L. and Block, M. R (1995). Talin processing occurs within adhesion plaques. Exp. Cell Res 217, 149-156.[Medline]

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				W. Sun, W. Hu, R. Xu, J. Jin, Z. M. Szulc, G. Zhang, S. H. Galadari, L. M. Obeid, and C. Mao Alkaline ceramidase 2 regulates {beta}1 integrin maturation and cell adhesion FASEB J, February 1, 2009; 23(2): 656 - 666. [Abstract] [Full Text] [PDF]

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				T. L. Helsten, T. A. Bunch, H. Kato, J. Yamanouchi, S. H. Choi, A. L. Jannuzi, C. C. Feral, M. H. Ginsberg, D. L. Brower, and S. J. Shattil Differences in Regulation of Drosophila and Vertebrate Integrin Affinity by Talin Mol. Biol. Cell, August 1, 2008; 19(8): 3589 - 3598. [Abstract] [Full Text] [PDF]

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				C. Le Clainche and M.-F. Carlier Regulation of Actin Assembly Associated With Protrusion and Adhesion in Cell Migration Physiol Rev, April 1, 2008; 88(2): 489 - 513. [Abstract] [Full Text] [PDF]

				A. Millon-Fremillon, D. Bouvard, A. Grichine, S. Manet-Dupe, M. R. Block, and C. Albiges-Rizo Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent {beta}1-integrin affinity J. Cell Biol., January 28, 2008; 180(2): 427 - 441. [Abstract] [Full Text] [PDF]

				B. Nieswandt, M. Moser, I. Pleines, D. Varga-Szabo, S. Monkley, D. Critchley, and R. Fassler Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo J. Exp. Med., December 24, 2007; 204(13): 3113 - 3118. [Abstract] [Full Text] [PDF]

				B. Patel, A. R. Gingras, A. A. Bobkov, L. M. Fujimoto, M. Zhang, R. C. Liddington, D. Mazzeo, J. Emsley, G. C. K. Roberts, I. L. Barsukov, et al. The Activity of the Vinculin Binding Sites in Talin Is Influenced by the Stability of the Helical Bundles That Make Up The Talin Rod J. Biol. Chem., March 17, 2006; 281(11): 7458 - 7467. [Abstract] [Full Text] [PDF]

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				D. D. Mruk and C. Y. Cheng Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis Endocr. Rev., October 1, 2004; 25(5): 747 - 806. [Abstract] [Full Text] [PDF]

				L. Tremuth, S. Kreis, C. Melchior, J. Hoebeke, P. Ronde, S. Plancon, K. Takeda, and N. Kieffer A Fluorescence Cell Biology Approach to Map the Second Integrin-binding Site of Talin to a 130-Amino Acid Sequence within the Rod Domain J. Biol. Chem., May 21, 2004; 279(21): 22258 - 22266. [Abstract] [Full Text] [PDF]

				I. L. Barsukov, A. Prescot, N. Bate, B. Patel, D. N. Floyd, N. Bhanji, C. R. Bagshaw, K. Letinic, G. Di Paolo, P. De Camilli, et al. Phosphatidylinositol Phosphate Kinase Type 1{gamma} and {beta}1-Integrin Cytoplasmic Domain Bind to the Same Region in the Talin FERM Domain J. Biol. Chem., August 15, 2003; 278(33): 31202 - 31209. [Abstract] [Full Text] [PDF]

				A. S. Coutts, E. MacKenzie, E. Griffith, and D. M. Black TES is a novel focal adhesion protein with a role in cell spreading J. Cell Sci., March 1, 2003; 116(5): 897 - 906. [Abstract] [Full Text] [PDF]

				D. Bouvard, L. Vignoud, S. Dupe-Manet, N. Abed, H.-N. Fournier, C. Vincent-Monegat, S. F. Retta, R. Fassler, and M. R. Block Disruption of Focal Adhesions by Integrin Cytoplasmic Domain-associated Protein-1alpha J. Biol. Chem., February 14, 2003; 278(8): 6567 - 6574. [Abstract] [Full Text] [PDF]

				M. A. Esteban-Barragan, P. Avila, M. Alvarez-Tejado, M. D. Gutierrez, A. Garcia-Pardo, F. Sanchez-Madrid, and M. O. Landazuri Role of the von Hippel-Lindau Tumor Suppressor Gene in the Formation of {beta}1-Integrin Fibrillar Adhesions Cancer Res., May 1, 2002; 62(10): 2929 - 2936. [Abstract] [Full Text] [PDF]

				R. A. ORLANDO, T. TAKEDA, B. ZAK, S. SCHMIEDER, V. M. BENOIT, T. MCQUISTAN, H. FURTHMAYR, and M. G. FARQUHAR The Glomerular Epithelial Cell Anti-Adhesin Podocalyxin Associates with the Actin Cytoskeleton through Interactions with Ezrin J. Am. Soc. Nephrol., August 1, 2001; 12(8): 1589 - 1598. [Abstract] [Full Text] [PDF]

				V Martel, L Vignoud, S Dupe, P Frachet, M. Block, and C Albiges-Rizo Talin controls the exit of the integrin alpha 5 beta 1 from an early compartment of the secretory pathway J. Cell Sci., January 6, 2000; 113(11): 1951 - 1961. [Abstract] [PDF]

				A. Bellissent–Waydelich, M.-T. Vanier, C. Albigès–Rizo, and P. Simon–Assmann Talin Concentrates to the Midbody Region During Mammalian Cell Cytokinesis J. Histochem. Cytochem., November 1, 1999; 47(11): 1357 - 1368. [Abstract] [Full Text]

				G Svineng and S Johansson Integrin subunits (beta)1C-1 and (beta)1C-2 expressed in GD25T cells are retained and degraded intracellularly rather than localised to the cell surface J. Cell Sci., January 12, 1999; 112(24): 4751 - 4761. [Abstract] [PDF]

				V. G. Gorgoulis, P. Zacharatos, A. Kotsinas, T. Liloglou, A. Kyroudi, M. Veslemes, A. Rassidakis, T. D. Halazonetis, J. K. Field, and C. Kittas Alterations of the p16-pRb Pathway and the Chromosome Locus 9p21�22 in Non-Small-Cell Lung Carcinomas : Relationship with p53 and MDM2 Protein Expression Am. J. Pathol., December 1, 1998; 153(6): 1749 - 1765. [Abstract] [Full Text] [PDF]

				M. L. Borowsky and R. O. Hynes Layilin, A Novel Talin-binding Transmembrane Protein Homologous with C-type Lectins, is Localized in Membrane Ruffles J. Cell Biol., October 19, 1998; 143(2): 429 - 442. [Abstract] [Full Text] [PDF]

				H. Priddle, L. Hemmings, S. Monkley, A. Woods, B. Patel, D. Sutton, G. A. Dunn, D. Zicha, and D. R. Critchley Disruption of the Talin Gene Compromises Focal Adhesion Assembly in Undifferentiated but Not Differentiated Embryonic Stem Cells J. Cell Biol., August 24, 1998; 142(4): 1121 - 1133. [Abstract] [Full Text] [PDF]

				J.-M. Heraud, C. Racaud-Sultan, D. Gironcel, C. Albiges-Rizo, T. Giacomini, S. Roques, V. Martel, M. Breton-Douillon, B. Perret, and H. Chap Lipid Products of Phosphoinositide 3-Kinase and Phosphatidylinositol 4',5'-Bisphosphate Are Both Required for ADP-dependent Platelet Spreading J. Biol. Chem., July 10, 1998; 273(28): 17817 - 17823. [Abstract] [Full Text] [PDF]

				J. Niewohner, I. Weber, M. Maniak, A. Muller-Taubenberger, and G. Gerisch Talin-Null Cells of Dictyostelium Are Strongly Defective in Adhesion to Particle and Substrate Surfaces and Slightly Impaired in Cytokinesis J. Cell Biol., July 28, 1997; 138(2): 349 - 361. [Abstract] [Full Text] [PDF]

				R. O. McCann and S. W. Craig The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to�mammals PNAS, May 27, 1997; 94(11): 5679 - 5684. [Abstract] [Full Text] [PDF]

				L Vignoud, C Albiges-Rizo, P Frachet, and M. Block NPXY motifs control the recruitment of the alpha5beta1 integrin in focal adhesions independently of the association of talin with the beta1 chain J. Cell Sci., January 6, 1997; 110(12): 1421 - 1430. [Abstract] [PDF]

				L Hemmings, D. Rees, V Ohanian, S. Bolton, A. Gilmore, B Patel, H Priddle, J. Trevithick, R. Hynes, and D. Critchley Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site J. Cell Sci., January 11, 1996; 109(11): 2715 - 2726. [Abstract] [PDF]

				A. Seelig, X. L. Blatter, A. Frentzel, and G. Isenberg Phospholipid Binding of Synthetic Talin Peptides Provides Evidence for an Intrinsic Membrane Anchor of Talin J. Biol. Chem., June 9, 2000; 275(24): 17954 - 17961. [Abstract] [Full Text] [PDF]

				D. Chu, N. Kakazu, M. J. Gorrin-Rivas, H.-P. Lu, M. Kawata, T. Abe, K. Ueda, and Y. Adachi Cloning and Characterization of LUN, a Novel RING Finger Protein That Is Highly Expressed in Lung and Specifically Binds to a Palindromic Sequence J. Biol. Chem., April 20, 2001; 276(17): 14004 - 14013. [Abstract] [Full Text] [PDF]

				V. Martel, C. Racaud-Sultan, S. Dupe, C. Marie, F. Paulhe, A. Galmiche, M. R. Block, and C. Albiges-Rizo Conformation, Localization, and Integrin Binding of Talin Depend on Its Interaction with Phosphoinositides J. Biol. Chem., June 8, 2001; 276(24): 21217 - 21227. [Abstract] [Full Text] [PDF]