Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Takegawa, K.
	Articles by Emr, S. D.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Takegawa, K.
	Articles by Emr, S. D.


Social Bookmarking

	What's this?

Auger, K. R., Serunian, L. A., Soltoff, S. P., Libby, P. and Cantley, L. C (1989). PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57, 167-175.[Medline]

Auger, K., Carpenter, C., Schoelson, S., Piwnica-Worms, H. and Cantley, L (1992). Reconstitution of purified PtdIns 3-kinase with middle t/pp60c-src expressed in insect cells. J. Biol. Chem 267, 5408-5415.[Abstract/Free Full Text]

Bankaitis, V. A., Johnson, L. M. and Emr, S. D (1986). Isolation of yeast mutants defective in protein targeting to the vacuole. Proc. Nat. Acad. Sci. USA 83, 9075-9079.[Abstract/Free Full Text]

Cantley, L. C., Auger, K. R., Carpenter, C., Duckworth, B., Graziani, A., Kapeller, R. and Soltoff, S (1991). Oncogenes and signal transduction. Cell 64, 281-302.[Medline]

Carpenter, C. L., Duckworth, B. C., Auger, K. R., Cohen, B., Schaffhausen, B. S. and Cantley, L. C (1990). Purification and characterization of phosphoinositide 3-kinase from rat liver. J. Biol. Chem 265, 19704-19711.[Abstract/Free Full Text]

Properties of SpVps34p, Vps34p and p110 (1994). and phosphorylation of cell growth\240 \240\340 \340Dhand et al., 1994. Lam et al., 1994.SpVps34p was not detected. Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit. J. Biol. Chem 268, 9478-9483.[Abstract/Free Full Text]

Christianson, T. W., Sikorski, R. S., Dante, M., Shero, J. H. and Hieter, P (1992). Multifunctional yeast high-copy-number shuttle vectors. Gene 110, 119-122.[Medline]

Dhand, R., Hara, K., Hiles, I., Bax, B., Gout, I., Panayotou, G., Fry, M. J., Yonezawa, K., Kasuga, M. and Waterfield, M. D (1994). PI 3-kinase: structural and functional analysis of intersubunit interactions. EMBO J 13, 511-521.[Medline]

Dieckman, C. L. and Tzagoloff, A (1985). Assembly of the mitochondrial membrane system. CBD6, a yeast nuclear gene necessary for synthesis of cytochrome b. J. Biol. Chem 260, 1513-1520.[Abstract/Free Full Text]

Feinberg, A. P. and Vogelstein, B (1983). A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem 132, 6-13.[Medline]

Flanagan, C. A., Schnieders, E. A., Emerick, A. W., R., K., Admon, A. and Thorner, J (1993). Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. Science 262, 1444-1448.[Abstract/Free Full Text]

Gout, I., Dhand, R., Hiles, I. D., Fry, M. J., Panayotou, G., Das, P., Truong, O., Totty, N. F., Hsuan, J., Booker, G. W., Campbell, I. D. and Waterfield, M. D (1993). The GTPase dynamin binds to and is activated by a subset of SH3 domains. Cell 75, 25-36.[Medline]

Grimm, C., Kohli, J., Murray, J. and Maundrell, K (1988). Genetic engineering of Schizosaccharomyces: a system for gene disruption and replacement using the ura4 gene as a selectable marker. Mol. Gen. Genet 215, 81-86.[Medline]

Hawkins, P. T. J., T. R. and Stephens, L. R (1992). Platelet-derived growth factor stimulates synthesis of PtdIns(3, 4, 5)-P3 by activating a PtdIns(4, 5)-P2 3-OH kinase. Nature 358, 157-159.[Medline]

Herman, P. K. and Emr, S. D (1990). Characterization of VPS34 , a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol. Cell. Biol 10, 6742-6754.[Abstract/Free Full Text]

Hiles, I. D., Otsu, M., Volinia, S., Fry, M. J., Guot, I., Dhand, R., Panayotou, G., Ruiz-Larrea, F., Thompson, A., Totty, N. F., Hsuan, J. J., Courtneidge, S. A., Parker, P. J. and Waterfield, M. D (1992). Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit. Cell 70, 419-429.[Medline]

Hong, Z. and Verma, D. P. S (1994). A phosphatidylinositol 3-kinase is induced during soybean nodule organogenesis and is associated with membrane proliferation. Proc. Nat. Acad. Sci. USA 91, 9617-9621.[Abstract/Free Full Text]

Hu, P., Mondino, A., Skolnik, E. Y. and Schlessinger, J (1993). Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85. Mol. Cell. Biol 13, 7677-7688.[Abstract/Free Full Text]

Hu, P. and Schlessinger, J (1994). Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta. Mol. Cell. Biol 14, 2577-2583.[Abstract/Free Full Text]

Joly, M., Kazlauskas, A., Fay, F. S. and Corvera, S (1994). Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. Science 263, 684-687.[Abstract/Free Full Text]

Jones, E. W (1977). Proteinase mutants of Saccharomyces cerevisiae. Genetics 85, 23-33.[Abstract/Free Full Text]

Kapeller, R., Chakrabarti, R., Cantley, L., Fay, F. and Corvera, S (1993). Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton. Mol. Cell. Biol 13, 6052-6063.[Abstract/Free Full Text]

Kleid, D. G., Yansura, D., Small, B., Dowbenko, D., Moore, M., Robertson, B. H. and Bachrach, H. L (1981). Cloned viral protein vaccine for foot-and-mouth disease: responses in cattle and swine. Science 214, 1125-1129.[Abstract/Free Full Text]

Klionsky, D. J., Banta, L. M. and Emr, S. D (1988). Intracellular sorting and processing of a yeast vacuolar hydrolase: Proteinase A propeptide contains vacuolar targeting information. Mol. Cell. Biol 8, 2105-2116.[Abstract/Free Full Text]

Klionsky, D. J., Herman, P. K. and Emr, S. D (1990). The fungal vacuole: Composition, function and biogenesis. Microbiol. Rev 54, 266-292.[Abstract/Free Full Text]

Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Ashford, V. A., Xuong, N. H., Taylor, S. S. and Sowadski, J. M (1991). Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253, 407-414.[Abstract/Free Full Text]

Lam, K., Carpenter, C. L., Ruderman, N. B., Friel, J. C. and Kelly, K. L (1994). The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. J. Biol. Chem 269, 20648-20652.[Abstract/Free Full Text]

McLeod, M., Stein, M. and Beach, D (1987). The product of the mei3+ gene, expressed under control of the mating-type locus, induces meiosis and sporulation in fission yeast. EMBO J 6, 729-736.[Medline]

Moreno, S., Klar, A. and Nurse, P (1991). Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Meth. Enzymol 194, 795-823.[Medline]

Okada, T., Kawano, Y., Sakakibara, T., Hazeki, O. and Ui, M (1994). Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes- Studies with a selective inhibitor wortmannin. J. Biol. Chem 269, 3568-3573.[Abstract/Free Full Text]

Okada, T., Sakuma, L., Fukui, Y., Hazeki, O. and Ui, M (1994). Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J. Biol. Chem 269, 3563-3567.[Abstract/Free Full Text]

Okazaki, K., Okazaki, K., Kume, K., Jinno, S., Tanaka, K. and Okayama, H (1990). High-frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation of Schizosaccharomyces pombe. Nucl. Acids Res 18, 6485-6489.[Abstract/Free Full Text]

Otsu, M., Hiles, I., Gout, I., Fry, M. J., Ruiz-Larrea, F., Panayotou, G., Thompson, A., Dhand, R., Hsuan, J., Totty, N., Smith, A. D., Morgan, S. J., Courtneidge, S. A., Parker, P. J. and Waterfield, M. D (1991). Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60 c-src complexes, and PI3-kinase. Cell 65, 91-104.[Medline]

Panayotou, G., Bax, B., Gout, I., Federwisch, M., Wroblowski, B., Dhand, R., Fry, M. J., Blundell, T. L., Wollmer, A. and Waterfield, M. D (1992). Interaction of the p85-subunit of Pl 3-kinase and its N-terminal SH2-domain with a PDGF receptor phosphorylation site- structural features and analysis of conformational changes. EMBO J 11, 4261-4272.[Medline]

Robinson, J. S., Klionsky, D. J., Banta, L. M. and Emr, S. D (1988). Protein sorting in Saccharomyces cerevisiae : isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol. Cell. Biol 8, 4936-4948.[Abstract/Free Full Text]

Rothman, J. H. and Stevens, T. H (1986). Protein sorting in yeast: Mutants defective in vacuole biogenesis mislocalization vacuolar proteins into the late secretory pathway. Cell 47, 1041-1051.[Medline]

Rothman, J. H., Yamashiro, C. T., Kane, P. M. and Stevens, T. H (1989). Protein targeting to the yeast vacuole. Trends Biochem. Sci 14, 347-350.[Medline]

Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B. and Erlich, H. A (1988). Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239, 88-91.

Schu, P. V., Takegawa, K., Fry, M. J., Stack, J. H., Waterfield, M. D. and Emr, S. D (1993). Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260, 88-91.[Abstract/Free Full Text]

Segal, A. W. and Abo, A (1993). The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem. Sci 18, 43-47.[Medline]

Stack, J. H., Herman, P. K., Schu, P. V. and Emr, S. D (1993). A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J 12, 2195-2204.[Medline]

Stack, J. H. and Emr, S. D (1994). Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J. Biol. Chem 269, 31552-31562.[Abstract/Free Full Text]

Stack, J. H., DeWald, D. B., Takegawa, K. and Emr, S. D (1995). Regulatory interactions between the Vps15 protein kinase and the Vps34 PI 3-kinase essential for signaling vesicle-mediated protein transport to the vacuole in yeast. J. Cell Biol 129, 321-334.[Abstract/Free Full Text]

Stephens, L., Hughes, K. and Irvine, R. F (1991). Pathways of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils. Nature 351, 33-39.[Medline]

Stephens, L. R., Jackson, T. R. and Hawkins, P. T (1993). Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system. Biochim. Biophys. Acta 1179, 27-75.[Medline]

Stephens, L., Cooke, F. T., Walters, R., Jackson, T., Volina, S., Gout, I., Waterfield, M. D. and Hawkins, P. T (1994). Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells. Curr. Biol 4, 203-214.[Medline]

Stephens, L., Smrcka, A., Cooke, F., Jackson, T. R., Sternweis, P. C. and Hawkins, P. T (1994). A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits. Cell 77, 83-93.[Medline]

Thelen, M., Wymann, M. P. and Langen, H (1994). Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guaninenucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc. Nat. Acad. Sci. USA 91, 4960-4964.[Abstract/Free Full Text]

Vlahos, C. J., Matter, W. F., Hui, K. Y. and Brown, R. F (1994). A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem 269, 5241-5248.[Abstract/Free Full Text]

Volinia, S., Dhand, R., Vanhaesebroeck, B., MacDougall, L. K., Stein, R., Zvelebil, M. J., Domin, J., Panaretou, C. and Waterfield, M. D (1995). A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system. EMBO J 14, 3339-3348.[Medline]

Walsh, J. P., Caldwell, K. K. and Majerus, P. W (1991). Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate. Proc. Nat. Acad. Sci. USA 88, 9184-9187.[Abstract/Free Full Text]

Welters, P., Takegawa, K., Emr, S. D. and Chrispeels, M. J (1994). AtVPS34, a phosphatidylinositol 3-kinase of Arabidopsis thaliana is an essential protein with homology to a calcium-dependent lipid binding domain. Proc. Nat. Acad. Sci. USA 91, 11398-11402.[Abstract/Free Full Text]

Wennstr\232m, S., Hawkins, P., Cooke, F., Hara, K., Yonezawa, K., Kasuga, M., Jackson, T., Claesson-Welsh, L. and Stephens, L (1994). Activationof phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr. Biol 4, 385-393.[Medline]

Yano, H., Nakanishi, S., Kimura, K., Hanai, N., Saitoh, Y., Fukui, Y., Nonomura, Y. and Matsuda, Y (1993). Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J. Biol. Chem 268, 25846-25856.[Abstract/Free Full Text]

Yoshida, S., Ohya, Y., Goebl, M., Nakano, A. and Anraku, Y (1994). A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae. J. Biol. Chem 269, 1166-1172.[Abstract/Free Full Text]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

S. Codlin and S. E. Mole
S. pombe btn1, the orthologue of the Batten disease gene CLN3, is required for vacuole protein sorting of Cpy1p and Golgi exit of Vps10p
J. Cell Sci., April 15, 2009; 122(8): 1163 - 1173.
[Abstract] [Full Text] [PDF]

L. Saavedra, V. Balbi, S. K. Dove, Y. Hiwatashi, K. Mikami, and M. Sommarin
Characterization of Phosphatidylinositol Phosphate Kinases from the Moss Physcomitrella patens: PpPIPK1 and PpPIPK2
Plant Cell Physiol., March 1, 2009; 50(3): 595 - 609.
[Abstract] [Full Text] [PDF]

K. O. Schink and M. Bolker
Coordination of Cytokinesis and Cell Separation by Endosomal Targeting of a Cdc42-specific Guanine Nucleotide Exchange Factor in Ustilago maydis
Mol. Biol. Cell, February 1, 2009; 20(3): 1081 - 1088.
[Abstract] [Full Text] [PDF]

T. Iwaki, H. Iefuji, Y. Hiraga, A. Hosomi, T. Morita, Y. Giga-Hama, and K. Takegawa
Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe
Microbiology, March 1, 2008; 154(3): 830 - 841.
[Abstract] [Full Text] [PDF]

M. Onishi, M. Iida, T. Koga, S. Yamada, A. Hirata, T. Iwaki, K. Takegawa, Y. Fukui, and H. Tachikawa
Schizosaccharomyces pombe Sst4p, a Conserved Vps27/Hrs Homolog, Functions Downstream of Phosphatidylinositol 3-Kinase Pik3p To Mediate Proper Spore Formation
Eukaryot. Cell, December 1, 2007; 6(12): 2343 - 2353.
[Abstract] [Full Text] [PDF]

T. Iwaki, M. Onishi, M. Ikeuchi, A. Kita, R. Sugiura, Y. Giga-Hama, Y. Fukui, and K. Takegawa
Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe
Microbiology, August 1, 2007; 153(8): 2753 - 2764.
[Abstract] [Full Text] [PDF]

T. Iwaki, A. Hosomi, S. Tokudomi, Y. Kusunoki, Y. Fujita, Y. Giga-Hama, N. Tanaka, and K. Takegawa
Vacuolar protein sorting receptor in Schizosaccharomyces pombe.
Microbiology, May 1, 2006; 152(Pt 5): 1523 - 1532.
[Abstract] [Full Text] [PDF]

P. Mitra, Y. Zhang, L. E. Rameh, M. P. Ivshina, D. McCollum, J. J. Nunnari, G. M. Hendricks, M. L. Kerr, S. J. Field, L. C. Cantley, et al.
A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast
J. Cell Biol., July 19, 2004; 166(2): 205 - 211.
[Abstract] [Full Text] [PDF]

T. Koga, M. Onishi, Y. Nakamura, A. Hirata, T. Nakamura, C. Shimoda, T. Iwaki, K. Takegawa, and Y. Fukui
Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe
Genes Cells, June 1, 2004; 9(6): 561 - 574.
[Abstract] [Full Text] [PDF]

S. K. Cho and S. L. Hofmann
pdf1, a Palmitoyl Protein Thioesterase 1 Ortholog in Schizosaccharomyces pombe: a Yeast Model of Infantile Batten Disease
Eukaryot. Cell, April 1, 2004; 3(2): 302 - 310.
[Abstract] [Full Text] [PDF]

T. Maeda, R. Sugiura, A. Kita, M. Saito, L. Deng, Y. He, Y. Lu, Y. Fujita, K. Takegawa, H. Shuntoh, et al.
Pmr1, a P-type ATPase, and Pdt1, an Nramp homologue, cooperatively regulate cell morphogenesis in fission yeast: The importance of Mn2+ homeostasis
Genes Cells, January 1, 2004; 9(1): 71 - 82.
[Abstract] [Full Text] [PDF]

B. Mueller-Roeber and C. Pical
Inositol Phospholipid Metabolism in Arabidopsis. Characterized and Putative Isoforms of Inositol Phospholipid Kinase and Phosphoinositide-Specific Phospholipase C
Plant Physiology, September 1, 2002; 130(1): 22 - 46.
[Abstract] [Full Text] [PDF]

H. Cheng, R. Sugiura, W. Wu, M. Fujita, Y. Lu, S. O. Sio, R. Kawai, K. Takegawa, H. Shuntoh, and T. Kuno
Role of the Rab GTP-Binding Protein Ypt3 in the Fission Yeast Exocytic Pathway and Its Connection to Calcineurin Function
Mol. Biol. Cell, August 1, 2002; 13(8): 2963 - 2976.
[Abstract] [Full Text] [PDF]

T. Uo, T. Yoshimura, N. Tanaka, K. Takegawa, and N. Esaki
Functional Characterization of Alanine Racemase from Schizosaccharomyces pombe: a Eucaryotic Counterpart to Bacterial Alanine Racemase
J. Bacteriol., April 1, 2001; 183(7): 2226 - 2233.
[Abstract] [Full Text]

D. H. Kim, Y.-J. Eu, C. M. Yoo, Y.-W. Kim, K. T. Pih, J. B. Jin, S. J. Kim, H. Stenmark, and I. Hwang
Trafficking of Phosphatidylinositol 3-Phosphate from the trans-Golgi Network to the Lumen of the Central Vacuole in Plant Cells
PLANT CELL, February 1, 2001; 13(2): 287 - 301.
[Abstract] [Full Text]

F. Blondeau, J. Laporte, S. Bodin, G. Superti-Furga, B. Payrastre, and J.-L. Mandel
Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway
Hum. Mol. Genet., September 1, 2000; 9(15): 2223 - 2229.
[Abstract] [Full Text] [PDF]

K. D. Sims, D. J. Straff, and M. B. Robinson
Platelet-derived Growth Factor Rapidly Increases Activity and Cell Surface Expression of the EAAC1 Subtype of Glutamate Transporter through Activation of Phosphatidylinositol 3-Kinase
J. Biol. Chem., February 18, 2000; 275(7): 5228 - 5237.
[Abstract] [Full Text] [PDF]

J. M. Murray and D. I. Johnson
Isolation and Characterization of Nrf1p, a Novel Negative Regulator of the Cdc42p GTPase in Schizosaccharomyces pombe
Genetics, January 1, 2000; 154(1): 155 - 165.
[Abstract] [Full Text]

R. K. McEwen, S. K. Dove, F. T. Cooke, G. F. Painter, A. B. Holmes, A. Shisheva, Y. Ohya, P. J. Parker, and R. H. Michell
Complementation Analysis in PtdInsP Kinase-deficient Yeast Mutants Demonstrates That Schizosaccharomyces pombe and Murine Fab1p Homologues Are Phosphatidylinositol 3-Phosphate 5-Kinases
J. Biol. Chem., November 26, 1999; 274(48): 33905 - 33912.
[Abstract] [Full Text] [PDF]

F. Gaits and P. Russell
Vacuole Fusion Regulated by Protein Phosphatase 2C in Fission Yeast
Mol. Biol. Cell, August 1, 1999; 10(8): 2647 - 2654.
[Abstract] [Full Text]

U. Siddhanta, J. McIlroy, A. Shah, Y. Zhang, and J. M. Backer
Distinct Roles for the p110{alpha} and hVPS34 Phosphatidylinositol 3'-Kinases in Vesicular Trafficking, Regulation of the Actin Cytoskeleton, and Mitogenesis
J. Cell Biol., December 14, 1998; 143(6): 1647 - 1659.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Takegawa, K.

Articles by Emr, S. D.

Search for Related Content

PubMed

PubMed Citation

Articles by Takegawa, K.

Articles by Emr, S. D.

Social Bookmarking

What's this?

				L. Saavedra, V. Balbi, S. K. Dove, Y. Hiwatashi, K. Mikami, and M. Sommarin Characterization of Phosphatidylinositol Phosphate Kinases from the Moss Physcomitrella patens: PpPIPK1 and PpPIPK2 Plant Cell Physiol., March 1, 2009; 50(3): 595 - 609. [Abstract] [Full Text] [PDF]

				K. O. Schink and M. Bolker Coordination of Cytokinesis and Cell Separation by Endosomal Targeting of a Cdc42-specific Guanine Nucleotide Exchange Factor in Ustilago maydis Mol. Biol. Cell, February 1, 2009; 20(3): 1081 - 1088. [Abstract] [Full Text] [PDF]

				T. Iwaki, H. Iefuji, Y. Hiraga, A. Hosomi, T. Morita, Y. Giga-Hama, and K. Takegawa Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe Microbiology, March 1, 2008; 154(3): 830 - 841. [Abstract] [Full Text] [PDF]

				M. Onishi, M. Iida, T. Koga, S. Yamada, A. Hirata, T. Iwaki, K. Takegawa, Y. Fukui, and H. Tachikawa Schizosaccharomyces pombe Sst4p, a Conserved Vps27/Hrs Homolog, Functions Downstream of Phosphatidylinositol 3-Kinase Pik3p To Mediate Proper Spore Formation Eukaryot. Cell, December 1, 2007; 6(12): 2343 - 2353. [Abstract] [Full Text] [PDF]

				T. Iwaki, M. Onishi, M. Ikeuchi, A. Kita, R. Sugiura, Y. Giga-Hama, Y. Fukui, and K. Takegawa Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe Microbiology, August 1, 2007; 153(8): 2753 - 2764. [Abstract] [Full Text] [PDF]

				T. Iwaki, A. Hosomi, S. Tokudomi, Y. Kusunoki, Y. Fujita, Y. Giga-Hama, N. Tanaka, and K. Takegawa Vacuolar protein sorting receptor in Schizosaccharomyces pombe. Microbiology, May 1, 2006; 152(Pt 5): 1523 - 1532. [Abstract] [Full Text] [PDF]

				P. Mitra, Y. Zhang, L. E. Rameh, M. P. Ivshina, D. McCollum, J. J. Nunnari, G. M. Hendricks, M. L. Kerr, S. J. Field, L. C. Cantley, et al. A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast J. Cell Biol., July 19, 2004; 166(2): 205 - 211. [Abstract] [Full Text] [PDF]

				T. Koga, M. Onishi, Y. Nakamura, A. Hirata, T. Nakamura, C. Shimoda, T. Iwaki, K. Takegawa, and Y. Fukui Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe Genes Cells, June 1, 2004; 9(6): 561 - 574. [Abstract] [Full Text] [PDF]

				S. K. Cho and S. L. Hofmann pdf1, a Palmitoyl Protein Thioesterase 1 Ortholog in Schizosaccharomyces pombe: a Yeast Model of Infantile Batten Disease Eukaryot. Cell, April 1, 2004; 3(2): 302 - 310. [Abstract] [Full Text] [PDF]

				T. Maeda, R. Sugiura, A. Kita, M. Saito, L. Deng, Y. He, Y. Lu, Y. Fujita, K. Takegawa, H. Shuntoh, et al. Pmr1, a P-type ATPase, and Pdt1, an Nramp homologue, cooperatively regulate cell morphogenesis in fission yeast: The importance of Mn2+ homeostasis Genes Cells, January 1, 2004; 9(1): 71 - 82. [Abstract] [Full Text] [PDF]

				B. Mueller-Roeber and C. Pical Inositol Phospholipid Metabolism in Arabidopsis. Characterized and Putative Isoforms of Inositol Phospholipid Kinase and Phosphoinositide-Specific Phospholipase C Plant Physiology, September 1, 2002; 130(1): 22 - 46. [Abstract] [Full Text] [PDF]

				H. Cheng, R. Sugiura, W. Wu, M. Fujita, Y. Lu, S. O. Sio, R. Kawai, K. Takegawa, H. Shuntoh, and T. Kuno Role of the Rab GTP-Binding Protein Ypt3 in the Fission Yeast Exocytic Pathway and Its Connection to Calcineurin Function Mol. Biol. Cell, August 1, 2002; 13(8): 2963 - 2976. [Abstract] [Full Text] [PDF]

				T. Uo, T. Yoshimura, N. Tanaka, K. Takegawa, and N. Esaki Functional Characterization of Alanine Racemase from Schizosaccharomyces pombe: a Eucaryotic Counterpart to Bacterial Alanine Racemase J. Bacteriol., April 1, 2001; 183(7): 2226 - 2233. [Abstract] [Full Text]

				D. H. Kim, Y.-J. Eu, C. M. Yoo, Y.-W. Kim, K. T. Pih, J. B. Jin, S. J. Kim, H. Stenmark, and I. Hwang Trafficking of Phosphatidylinositol 3-Phosphate from the trans-Golgi Network to the Lumen of the Central Vacuole in Plant Cells PLANT CELL, February 1, 2001; 13(2): 287 - 301. [Abstract] [Full Text]

				F. Blondeau, J. Laporte, S. Bodin, G. Superti-Furga, B. Payrastre, and J.-L. Mandel Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway Hum. Mol. Genet., September 1, 2000; 9(15): 2223 - 2229. [Abstract] [Full Text] [PDF]

				K. D. Sims, D. J. Straff, and M. B. Robinson Platelet-derived Growth Factor Rapidly Increases Activity and Cell Surface Expression of the EAAC1 Subtype of Glutamate Transporter through Activation of Phosphatidylinositol 3-Kinase J. Biol. Chem., February 18, 2000; 275(7): 5228 - 5237. [Abstract] [Full Text] [PDF]

				J. M. Murray and D. I. Johnson Isolation and Characterization of Nrf1p, a Novel Negative Regulator of the Cdc42p GTPase in Schizosaccharomyces pombe Genetics, January 1, 2000; 154(1): 155 - 165. [Abstract] [Full Text]

				R. K. McEwen, S. K. Dove, F. T. Cooke, G. F. Painter, A. B. Holmes, A. Shisheva, Y. Ohya, P. J. Parker, and R. H. Michell Complementation Analysis in PtdInsP Kinase-deficient Yeast Mutants Demonstrates That Schizosaccharomyces pombe and Murine Fab1p Homologues Are Phosphatidylinositol 3-Phosphate 5-Kinases J. Biol. Chem., November 26, 1999; 274(48): 33905 - 33912. [Abstract] [Full Text] [PDF]

				F. Gaits and P. Russell Vacuole Fusion Regulated by Protein Phosphatase 2C in Fission Yeast Mol. Biol. Cell, August 1, 1999; 10(8): 2647 - 2654. [Abstract] [Full Text]

				U. Siddhanta, J. McIlroy, A. Shah, Y. Zhang, and J. M. Backer Distinct Roles for the p110{alpha} and hVPS34 Phosphatidylinositol 3'-Kinases in Vesicular Trafficking, Regulation of the Actin Cytoskeleton, and Mitogenesis J. Cell Biol., December 14, 1998; 143(6): 1647 - 1659. [Abstract] [Full Text] [PDF]