Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring

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Auerbach, R. and Auerbach, W (1982). Regional differences in the growth of normal and neoplastic cells. Science 215, 127-134.[Abstract/Free Full Text]

Bascom, C. C., Wolfshohl, J. R., Coffey, R. J., Madisen, L., Webb, N. R., Purchio, A. R., Derynck, R. and Moses, H. L (1989). Complex regulation of transforming growth factor1, 2 and3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors 1 and2. Mol. Cell. Biol 9, 5508-5515.[Abstract/Free Full Text]

Bascom, C. C., Sipes, N. J., Coffey, R. J. and Moses, H. L (1989). Regulation of epithelial cell proliferation by transforming growth factors. J. Cell. Biochem 39, 25-32.[Medline]

Border, W. A., Okuda, S., Languino, L. R., Sporn, M. B. and Ruoslahti, E (1990). Suppression of experimental glomerulonephritis by antiserum against transforming growth factor1. Nature 346, 371-374.[Medline]

Broekelmann, T. J., Limper, A. H., Colby, T. V. and McDonald, J. A (1991). Transforming growth factor1is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc. Nat. Acad. Sci. USA 88, 6642-6646.[Abstract/Free Full Text]

Castilla, A., Prieto, J. and Fausto, N (1991). Transforming growth factorsand in chronic liver disease. New Eng. J. Med 324, 933-940.[Abstract]

Chen, R. H., Ebner, R. and Derynck, R (1993). Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-activities. Science 260, 1335-1338.[Abstract/Free Full Text]

Connor, T. B., Roberts, A. B., Sporn, M. B., Danielpour, D., Dart, L. L., Michels, R. G., Bustros, S. de, Enger, C., Kato, H., Lansing, M., Hayashi, H. and Glaser, B. M (1989). Correlation of fibrosis and transforming growth factortype 2 levels in the eye. J. Clin. Invest 83, 1661-1666.

Danielpour, D., Kim, K-Y., Dart, L. L., Watanabe, S., Roberts, A. B. and Sporn, M. B (1989). Sandwich enzyme-linked immunosorbent assays (SELISAs) quantitate and distinguish two forms of transforming growth factor-beta (TGF-1 and TGF- 2) in complex biological fluids. Growth Factors 2, 61-71.[Medline]

Gatherer, D., ten Dijke, P., Baird, D. T. and Akhurst, R. J (1990). Expression of TGFisoforms during first trimester human embryogenesis. Development 110, 445-460.[Abstract/Free Full Text]

Graycar, J. L., Miller, D. A., Arrick, B. A., Lyons, R. M., Moses, H. L. and Derynck, R (1989). Human transforming growth factor-3: recombinant expression, purification and biological activities in comparison with transforming growth factors- 1 and2. Mol. Endocrinol 3, 1977-1986.[Abstract/Free Full Text]

Heldin, C.-H. and Westermark, B (1989). Platelet-derived growth factors: a family of isoforms that bind to two distinct receptors. Br. Med. Bull 45, 453-464.[Abstract/Free Full Text]

Jennings, J. C., Mohan, S., Linkhart, T. A., Widstrom, R. and Baylink, D. J (1988). Comparison of the biological activity of TGF-beta 1 and TGF-beta 2: differential activity in endothelial cells. J. Cell. Physiol 137, 167-172.[Medline]

Ksander, G. A., Ogawa, Y, Chu, G. H., McMullin, H., Rossenblatt, J. S. and McPherson, J. M (1990). Exogenous transforming growth factor-2enhances connective tissue formation and wound strength in guinea pig dermal wound healing by secondary intent. Ann. Surg 211, 288-294.[Medline]

Lepisto, J., Laato, M., Ninikoski, J., Lundberg, C., Gerdin, B. and Heldin, C-H (1992). Effects of homodimeric isoforms of platelet-derived growthfactor (PDGF-AA and PDGF-BB) on wound healing in rats. J. Surg. Res 53, 596-601.[Medline]

McCartney-Francis, N., Mizel, D., Wong, H., Wahl, L. and Wahl, S (1990). TGF-regulates production of growth factors and TGF- by human peripheral blood monocytes. Growth Factors 4, 27-35.[Medline]

Merwin, J. R., Newman, W., Beall, D., Tucker, A. and Madri, J. A (1991). Vascular cells respond differentially to transforming growth factors beta1 and beta2. Am. J. Pathol 138, 37-51.[Abstract]

Millan, F. A., Denhez, F., Kondaiah, P. and Akhurst, R. J (1991). Embryonic gene expression patterns of TGF1, 2 and3 suggest different developmental functions in vivo. Development 111, 131-144.[Abstract]

Mustoe, T. A., Pierce, G. F., Thomason, A., Gramates, P., Sporn, M. B. and Deuel, T. F (1987). Accelerated healing of incisional wounds in rats induced by transforming growth factor-. Science 237, 1333-1336.[Abstract/Free Full Text]

O'Reilly, M. A., Danielpour, D., Roberts, A. B. and Sporn, M. B (1992). Regulation of expression of transforming growth factor-2 by transforming growth factor- isoforms is dependent upon cell type. Growth Factors 6, 193-201.[Medline]

Pelton, R. W., Dickinson, M. E., Moses, H. L. and Hogan, B. L. M (1990). In situ hybridization analysis of TGF-3RNA expression during mouse development: comparative studies with TGF- 1and TGF-2. Development 110, 609-620.[Abstract/Free Full Text]

Pelton, R. W., Saxena, B., Jones, M., Moses, H. L. and Gold, L. I (1991). Immunohistochemical localization of TGF-1, TGF- 2 and TGF-3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J. Cell Biol 115, 091-1105.

Roberts, A. B., Kondaiah, P., Rosa, F., Watanabe, S., Good, P., Danielpour, D., Roche, N. S., Rebbert, M. L., Dawid, I. B. and Sporn, M. B (1990). Mesoderm induction in Xenopus laevis distinguishes between the various TGF-isoforms. Growth Factors 3, 277-286.[Medline]

Schmid, P., Cox, D., Bilbe, G., Maier, R. and McMaster, G. K (1991). Differential expression of TGF1, 2 and3 genes during mouse embryogenesis. Development 111, 117-130.[Abstract]

Shah, M., Foreman, D. M. and Ferguson, M. W. J (1992). Control of scarring in adult wounds by neutralising antibody to transforming growth factor. Lancet 339, 213-214.[Medline]

Shah, M., Foreman, D. M. and Ferguson, M. W. J (1994). Neutralising antibody to TGF-1, 2reduces cutaneous scarring in adult rodents. J. Cell Sci 107, 1137-1157.[Abstract]

Siegbahn, A., Hammacher, A., Westermark, B. and Heldin, C.-H (1990). Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes and granulocytes. J. Clin. Invest 85, 916-920.

Sporn, M. B., Roberts, A. B., Shull, J. H., Smith, J. M., Ward, J. N. and Sodek, J (1983). Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo. Science 219, 1329-1331.[Abstract/Free Full Text]

Whitby, D. J. and Ferguson, M. W. J (1991). The extracellular matrix of lip wounds in fetal, neonatal and adult mice. Development 112, 651-668.[Abstract]

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[Full Text] [PDF]

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J. Biol. Chem., May 24, 2002; 277(22): 19991 - 19997.
[Abstract] [Full Text] [PDF]

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TGF-beta isoform release and activation during in vitro bronchial epithelial wound repair
Am J Physiol Lung Cell Mol Physiol, January 1, 2002; 282(1): L115 - L123.
[Abstract] [Full Text] [PDF]

G. L. Masinde, X. Li, W. Gu, H. Davidson, S. Mohan, and D. J. Baylink
Identification of Wound Healing/Regeneration Quantitative Trait Loci (QTL) at Multiple Time Points that Explain Seventy Percent of Variance in (MRL/MpJ and SJL/J) Mice F2 Population
Genome Res., December 1, 2001; 11(12): 2027 - 2033.
[Abstract] [Full Text] [PDF]

Q. Liu, T.-Y. Ling, H.-S. Shieh, F. E. Johnson, J. S. Huang, and S. S. Huang
Identification of the High Affinity Binding Site in Transforming Growth Factor-beta Involved in Complex Formation with alpha 2-Macroglobulin. IMPLICATIONS REGARDING THE MOLECULAR MECHANISMS OF COMPLEX FORMATION BETWEEN alpha 2-MACROGLOBULIN AND GROWTH FACTORS, CYTOKINES, AND HORMONES
J. Biol. Chem., November 30, 2001; 276(49): 46212 - 46218.
[Abstract] [Full Text] [PDF]

N. Chegini, K. Kotseos, Y. Zhao, B. Bennett, F. W. McLean, M. P. Diamond, L. Holmdahl, and J. Burns
Differential expression of TGF-{beta}1 and TGF-{beta}3 in serosal tissues of human intraperitoneal organs and peritoneal adhesions
Hum. Reprod., June 1, 2001; 16(6): 1291 - 1300.
[Abstract] [Full Text] [PDF]

D. G. Dillard, S. Muller, C. Cohen, D. Bloch, J. M. Del Gaudio, and A. A. Gal
High Tumor Grade in Salivary Gland Mucoepidermoid Carcinomas and Loss of Expression of Transforming Growth Factor {beta} Receptor Type II
Arch Otolaryngol Head Neck Surg, June 1, 2001; 127(6): 683 - 686.
[Abstract] [Full Text] [PDF]

C. Soo, F.-Y. Hu, X. Zhang, Y. Wang, S. R. Beanes, H. P. Lorenz, M. H. Hedrick, R. J. Mackool, A. Plaas, S.-J. Kim, et al.
Differential Expression of Fibromodulin, a Transforming Growth Factor-{beta} Modulator, in Fetal Skin Development and Scarless Repair
Am. J. Pathol., August 1, 2000; 157(2): 423 - 433.
[Abstract] [Full Text] [PDF]

D. B. Hom
A New Era of Discovery in Facial Plastic Surgery
Arch Facial Plast Surg, July 1, 2000; 2(3): 166 - 172.
[Abstract] [Full Text] [PDF]

P. B. Saadeh, B. J. Mehrara, D. S. Steinbrech, J. A. Spector, J. A. Greenwald, G. S. Chin, H. Ueno, G. K. Gittes, and M. T. Longaker
Mechanisms of Fibroblast Growth Factor-2 Modulation of Vascular Endothelial Growth Factor Expression by Osteoblastic Cells
Endocrinology, June 1, 2000; 141(6): 2075 - 2083.
[Abstract] [Full Text] [PDF]

D. G. Dillard, C. Cohen, S. Muller, J. Del Gaudio, O. Reichman, B. Parrish, D. Rackley, and A. A. Gal
Immunolocalization of Activated Transforming Growth Factor {beta}1 in Juvenile Nasopharyngeal Angiofibroma
Arch Otolaryngol Head Neck Surg, June 1, 2000; 126(6): 723 - 725.
[Abstract] [Full Text] [PDF]

M. F. Cordeiro, S. S. Bhattacharya, G. S. Schultz, and P. T. Khaw
TGF-{beta}1, -{beta}2, and -{beta}3 In Vitro: Biphasic Effects on Tenon�s Fibroblast Contraction, Proliferation, and Migration
Invest. Ophthalmol. Vis. Sci., March 1, 2000; 41(3): 756 - 763.
[Abstract] [Full Text]

G. I Mason, J. Hamburger, and J. B Matthews
Mast cells, extracellular matrix components, TGFbeta isoforms and TGFbeta receptor expression in labial salivary glands in systemic sclerosis
Ann Rheum Dis, March 1, 2000; 59(3): 183 - 189.
[Abstract] [Full Text]

E. PIEK, C.-H. HELDIN, and P. TEN DIJKE
Specificity, diversity, and regulation in TGF-{beta} superfamily signaling
FASEB J, December 1, 1999; 13(15): 2105 - 2124.
[Abstract] [Full Text]

S. S. Huang, M. Zhou, F. E. Johnson, H.-S. Shieh, and J. S. Huang
An Active Site of Transforming Growth Factor-beta 1 for Growth Inhibition and Stimulation
J. Biol. Chem., September 24, 1999; 274(39): 27754 - 27758.
[Abstract] [Full Text] [PDF]

A. J. Singer and R. A.F. Clark
Cutaneous Wound Healing
N. Engl. J. Med., September 2, 1999; 341(10): 738 - 746.
[Full Text] [PDF]

M. F. Cordeiro, J. A. Gay, and P. T. Khaw
Human Anti-Transforming Growth Factor-{beta}2 Antibody: A New Glaucoma Anti-Scarring Agent
Invest. Ophthalmol. Vis. Sci., September 1, 1999; 40(10): 2225 - 2234.
[Abstract] [Full Text] [PDF]

J. V. Jester, J. Huang, P. A. Barry-Lane, W. W-Y. Kao, W. M. Petroll, and H. D. Cavanagh
Transforming Growth Factor{beta}-Mediated Corneal Myofibroblast Differentiation Requires Actin and Fibronectin Assembly
Invest. Ophthalmol. Vis. Sci., August 1, 1999; 40(9): 1959 - 1967.
[Abstract] [Full Text] [PDF]

M. F. Cordeiro, M. B. Reichel, J. A. Gay, F. D�Esposita, R. A. Alexander, and P. T. Khaw
Transforming Growth Factor-{beta}1, -{beta}2, and -{beta}3 In Vivo: Effects on Normal and Mitomycin C-Modulated Conjunctival Scarring
Invest. Ophthalmol. Vis. Sci., August 1, 1999; 40(9): 1975 - 1982.
[Abstract] [Full Text] [PDF]

B. C. McKaig, S. S. Makh, C. J. Hawkey, D. K. Podolsky, and Y. R. Mahida
Normal human colonic subepithelial myofibroblasts enhance epithelial migration (restitution) via TGF-beta 3
Am J Physiol Gastrointest Liver Physiol, May 1, 1999; 276(5): G1087 - G1093.
[Abstract] [Full Text] [PDF]

J. Li, K. Foitzik, E. Calautti, H. Baden, T. Doetschman, and G. P. Dotto
TGF-beta 3, but Not TGF-beta 1, Protects Keratinocytes against 12-O-Tetradecanoylphorbol-13-acetate-induced Cell Death in Vitro and in Vivo
J. Biol. Chem., February 12, 1999; 274(7): 4213 - 4219.
[Abstract] [Full Text] [PDF]

M F CORDEIRO and P T KHAW
The healing optic nerve in glaucoma: transforming growth factor beta �and optic nerve head remodelling
Br J Ophthalmol, February 1, 1999; 83(2): 132 - 133.
[Full Text]

Y Taya, S O'Kane, and M. Ferguson
Pathogenesis of cleft palate in TGF-beta3 knockout mice
Development, January 9, 1999; 126(17): 3869 - 3879.
[Abstract] [PDF]

L. Yang, C. X. Qiu, A. Ludlow, M. W. J. Ferguson, and G. Brunner
Active Transforming Growth Factor-� in Wound Repair : Determination Using a New Assay
Am. J. Pathol., January 1, 1999; 154(1): 105 - 111.
[Abstract] [Full Text] [PDF]

J. Wang, H. Zheng, C.-C. Sung, K. K. Richter, and M. Hauer-Jensen
Cellular Sources of Transforming Growth Factor-� Isoforms in Early and Chronic Radiation Enteropathy
Am. J. Pathol., November 1, 1998; 153(5): 1531 - 1540.
[Abstract] [Full Text] [PDF]

M. B Reichel, M F. Cordeiro, R. A Alexander, I. A Cree, S. S Bhattacharya, and P. T Khaw
New model of conjunctival scarring in the mouse eye
Br J Ophthalmol, September 1, 1998; 82(9): 1072 - 1077.
[Abstract] [Full Text]

Y. KAJI, T. MITA, H. OBATA, T. TSURU, K. SOYA, E. SHIRASAWA, H. SAKAI, A. HANYU, M. KATO, and H. YAMASHITA
Expression of transforming growth factor beta �superfamily and their receptors in the corneal stromal wound healing process after excimer laser keratectomy
Br J Ophthalmol, April 1, 1998; 82(4): 456g - 456.
[Full Text]

M. R. Ward, A. Agrotis, P. Kanellakis, R. Dilley, G. Jennings, and A. Bobik
Inhibition of Protein Tyrosine Kinases Attenuates Increases in Expression of Transforming Growth Factor-� Isoforms and Their Receptors Following Arterial Injury
Arterioscler Thromb Vasc Biol, November 1, 1997; 17(11): 2461 - 2470.
[Abstract] [Full Text]

S. S. Huang, Q. Liu, F. E. Johnson, Y. Konish, and J. S. Huang
Transforming Growth Factor beta �Peptide Antagonists and Their Conversion to Partial Agonists
J. Biol. Chem., October 24, 1997; 272(43): 27155 - 27159.
[Abstract] [Full Text] [PDF]

Q. Liu, S. S. Huang, and J. S. Huang
Function of the Type V Transforming Growth Factor beta �Receptor in Transforming Growth Factor beta -induced Growth Inhibition of Mink Lung Epithelial Cells
J. Biol. Chem., July 25, 1997; 272(30): 18891 - 18895.
[Abstract] [Full Text] [PDF]

M. Lyon, G. Rushton, and J. T. Gallagher
The Interaction of the Transforming Growth Factor-beta s with Heparin/Heparan Sulfate Is Isoform-specific
J. Biol. Chem., July 18, 1997; 272(29): 18000 - 18006.
[Abstract] [Full Text] [PDF]

L. Wu, A. Siddiqui, D. E. Morris, D. A. Cox, S. I. Roth, and T. A. Mustoe
Transforming Growth Factor {beta}3 (TGF{beta}3) Accelerates Wound Healing Without Alteration of Scar Prominence: Histologic and Competitive Reverse-Transcription-Polymerase Chain Reaction Studies
Arch Surg, July 1, 1997; 132(7): 753 - 760.
[Abstract] [PDF]

S. Frank, M. Madlener, and S. Werner
Transforming Growth Factors beta1, beta2, and beta3 and Their Receptors Are Differentially Regulated during Normal and Impaired Wound Healing
J. Biol. Chem., April 26, 1996; 271(17): 10188 - 10193.
[Abstract] [Full Text] [PDF]

B. C. McKaig, K. Hughes, P. J. Tighe, and Y. R. Mahida
Differential expression of TGF-beta isoforms by normal and inflammatory bowel disease intestinal myofibroblasts
Am J Physiol Cell Physiol, January 1, 2002; 282(1): C172 - C182.
[Abstract] [Full Text] [PDF]

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