Formation of stable microspikes containing actin and the 55 kDa actin bundling protein, fascin, is a consequence of cell adhesion to thrombospondin-1: implications for the anti-adhesive activities of thrombospondin-1

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				S. Pellegrin and H. Mellor Actin stress fibres J. Cell Sci., October 15, 2007; 120(20): 3491 - 3499. [Abstract] [Full Text] [PDF]

				R. Chakravarti, V. Sapountzi, and J. C. Adams Functional Role of Syndecan-1 Cytoplasmic V Region in Lamellipodial Spreading, Actin Bundling, and Cell Migration Mol. Biol. Cell, August 1, 2005; 16(8): 3678 - 3691. [Abstract] [Full Text] [PDF]

				A. W. Orr, C. A. Elzie, D. F. Kucik, and J. E. Murphy-Ullrich Thrombospondin signaling through the calreticulin/LDL receptor-related protein co-complex stimulates random and directed cell migration J. Cell Sci., July 15, 2003; 116(14): 2917 - 2927. [Abstract] [Full Text] [PDF]

				Y. Levy, D. Ronen, A. D. Bershadsky, and Y. Zick Sustained Induction of ERK, Protein Kinase B, and p70 S6 Kinase Regulates Cell Spreading and Formation of F-actin Microspikes Upon Ligation of Integrins by Galectin-8, a Mammalian Lectin J. Biol. Chem., April 11, 2003; 278(16): 14533 - 14542. [Abstract] [Full Text] [PDF]

				A. U. Jawhari, A. Buda, M. Jenkins, K. Shehzad, C. Sarraf, M. Noda, M. J. G. Farthing, M. Pignatelli, and J. C. Adams Fascin, an Actin-Bundling Protein, Modulates Colonic Epithelial Cell Invasiveness and Differentiation in Vitro Am. J. Pathol., January 1, 2003; 162(1): 69 - 80. [Abstract] [Full Text] [PDF]

				Y. Tseng, B. W. Schafer, S. C. Almo, and D. Wirtz Functional Synergy of Actin Filament Cross-linking Proteins J. Biol. Chem., July 5, 2002; 277(28): 25609 - 25616. [Abstract] [Full Text] [PDF]

				N. Anilkumar, D. S. Annis, D. F. Mosher, and J. C. Adams Trimeric assembly of the C-terminal region of Thrombospondin-1 or Thrombospondin-2 is necessary for cell spreading and fascin spike organisation J. Cell Sci., January 6, 2002; 115(11): 2357 - 2366. [Abstract] [Full Text] [PDF]

				J. C. Adams, N. Kureishy, and A. L. Taylor A Role for Syndecan-1 in Coupling Fascin Spike Formation by Thrombospondin-1 J. Cell Biol., March 19, 2001; 152(6): 1169 - 1182. [Abstract] [Full Text] [PDF]

				J. C. Adams and M. A. Schwartz Stimulation of Fascin Spikes by Thrombospondin-1 Is Mediated by the GTPases Rac and Cdc42 J. Cell Biol., August 21, 2000; 150(4): 807 - 822. [Abstract] [Full Text] [PDF]

				A. Ridley Rho GTPases: Integrating Integrin Signaling J. Cell Biol., August 21, 2000; 150(4): F107 - F109. [Abstract] [Full Text] [PDF]

				J. C. Adams, J. D. Clelland, G. D.M. Collett, F. Matsumura, S. Yamashiro, and L. Zhang Cell-Matrix Adhesions Differentially Regulate Fascin Phosphorylation Mol. Biol. Cell, December 1, 1999; 10(12): 4177 - 4190. [Abstract] [Full Text]

				H. C. Krutzsch, B. J. Choe, J. M. Sipes, N.-h. Guo, and D. D. Roberts Identification of an alpha 3beta 1 Integrin Recognition Sequence in Thrombospondin-1 J. Biol. Chem., August 20, 1999; 274(34): 24080 - 24086. [Abstract] [Full Text] [PDF]

				S. E. Goldblum, B. A. Young, P. Wang, and J. E. Murphy-Ullrich Thrombospondin-1 Induces Tyrosine Phosphorylation of Adherens Junction Proteins and Regulates an Endothelial Paracellular Pathway Mol. Biol. Cell, May 1, 1999; 10(5): 1537 - 1551. [Abstract] [Full Text]

				S. Chandrasekaran, N.-h. Guo, R. G. Rodrigues, J. Kaiser, and D. D. Roberts Pro-adhesive and Chemotactic Activities of Thrombospondin-1 for Breast Carcinoma Cells Are Mediated by alpha 3beta 1 Integrin and Regulated by Insulin-like Growth Factor-1 and CD98 J. Biol. Chem., April 16, 1999; 274(16): 11408 - 11416. [Abstract] [Full Text] [PDF]

				T. R. Kyriakides, Y.-H. Zhu, Z. Yang, and P. Bornstein The Distribution of the Matricellular Protein Thrombospondin 2 in Tissues of Embryonic and Adult Mice J. Histochem. Cytochem., September 1, 1998; 46(9): 1007 - 1016. [Abstract] [Full Text]

				S. Yamashiro, Y. Yamakita, S. Ono, and F. Matsumura Fascin, an Actin-bundling Protein, Induces Membrane Protrusions and Increases Cell Motility of Epithelial Cells Mol. Biol. Cell, May 1, 1998; 9(5): 993 - 1006. [Abstract] [Full Text]

				T. R. Kyriakides, Y.-H. Zhu, L. T. Smith, S. D. Bain, Z. Yang, M. T. Lin, K. G. Danielson, R. V. Iozzo, M. LaMarca, C. E. McKinney, et al. Mice That Lack Thrombospondin 2�Display Connective Tissue Abnormalities That Are Associated with Disordered Collagen Fibrillogenesis, an Increased Vascular Density, and a Bleeding Diathesis J. Cell Biol., January 26, 1998; 140(2): 419 - 430. [Abstract] [Full Text] [PDF]

				J. C. Adams Characterization of Cell-Matrix Adhesion Requirements for the Formation of Fascin Microspikes Mol. Biol. Cell, November 1, 1997; 8(11): 2345 - 2363. [Abstract] [Full Text]

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