Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling

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				M. Kobayashi, T. Yoshida, D. Takeuchi, V. C. Jones, K. Shigematsu, D. N. Herndon, and F. Suzuki Gr-1+CD11b+ cells as an accelerator of sepsis stemming from Pseudomonas aeruginosa wound infection in thermally injured mice J. Leukoc. Biol., June 1, 2008; 83(6): 1354 - 1362. [Abstract] [Full Text] [PDF]

				D. Marsh, S. Dickinson, G. W. Neill, J. F. Marshall, I. R. Hart, and G. J. Thomas {alpha}v{beta}6 Integrin Promotes the Invasion of Morphoeic Basal Cell Carcinoma through Stromal Modulation Cancer Res., May 1, 2008; 68(9): 3295 - 3303. [Abstract] [Full Text] [PDF]

				T. Tabata, H. Kawakatsu, E. Maidji, T. Sakai, K. Sakai, J. Fang-Hoover, M. Aiba, D. Sheppard, and L. Pereira Induction of an Epithelial Integrin {alpha}v{beta}6 in Human Cytomegalovirus-Infected Endothelial Cells Leads to Activation of Transforming Growth Factor-{beta}1 and Increased Collagen Production Am. J. Pathol., April 1, 2008; 172(4): 1127 - 1140. [Abstract] [Full Text] [PDF]

				L. A. Koopman Van Aarsen, D. R. Leone, S. Ho, B. M. Dolinski, P. E. McCoon, D. J. LePage, R. Kelly, G. Heaney, P. Rayhorn, C. Reid, et al. Antibody-Mediated Blockade of Integrin {alpha}v 6 Inhibits Tumor Progression In vivo by a Transforming Growth Factor- Regulated Mechanism Cancer Res., January 15, 2008; 68(2): 561 - 570. [Abstract] [Full Text] [PDF]

				G. S. Horan, S. Wood, V. Ona, D. J. Li, M. E. Lukashev, P. H. Weinreb, K. J. Simon, K. Hahm, N. E. Allaire, N. J. Rinaldi, et al. Partial Inhibition of Integrin {alpha}v 6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation Am. J. Respir. Crit. Care Med., January 1, 2008; 177(1): 56 - 65. [Abstract] [Full Text] [PDF]

				S. H. Hausner, D. DiCara, J. Marik, J. F. Marshall, and J. L. Sutcliffe Use of a Peptide Derived from Foot-and-Mouth Disease Virus for the Noninvasive Imaging of Human Cancer: Generation and Evaluation of 4-[18F]Fluorobenzoyl A20FMDV2 for In vivo Imaging of Integrin {alpha}v{beta}6 Expression with Positron Emission Tomography Cancer Res., August 15, 2007; 67(16): 7833 - 7840. [Abstract] [Full Text] [PDF]

				A. N. Elayadi, K. N. Samli, L. Prudkin, Y.-H. Liu, A. Bian, X.-J. Xie, I. I. Wistuba, J. A. Roth, M. J. McGuire, and K. C. Brown A Peptide Selected by Biopanning Identifies the Integrin {alpha}v{beta}6 as a Prognostic Biomarker for Nonsmall Cell Lung Cancer Cancer Res., June 15, 2007; 67(12): 5889 - 5895. [Abstract] [Full Text] [PDF]

				A. G. Ramsay, M. D. Keppler, M. Jazayeri, G. J. Thomas, M. Parsons, S. Violette, P. Weinreb, I. R. Hart, and J. F. Marshall HS1-Associated Protein X-1 Regulates Carcinoma Cell Migration and Invasion via Clathrin-Mediated Endocytosis of Integrin {alpha}v{beta}6 Cancer Res., June 1, 2007; 67(11): 5275 - 5284. [Abstract] [Full Text] [PDF]

				G. Otsuka, A. Stempien-Otero, A. D. Frutkin, and D. A. Dichek Mechanisms of TGF-{beta}1-Induced Intimal Growth: Plasminogen-Independent Activities of Plasminogen Activator Inhibitor-1 and Heterogeneous Origin of Intimal Cells Circ. Res., May 11, 2007; 100(9): 1300 - 1307. [Abstract] [Full Text] [PDF]

				D. DiCara, C. Rapisarda, J. L. Sutcliffe, S. M. Violette, P. H. Weinreb, I. R. Hart, M. J. Howard, and J. F. Marshall Structure-Function Analysis of Arg-Gly-Asp Helix Motifs in {alpha}vbeta6 Integrin Ligands J. Biol. Chem., March 30, 2007; 282(13): 9657 - 9665. [Abstract] [Full Text] [PDF]

				K. Hahm, M. E. Lukashev, Y. Luo, W. J. Yang, B. M. Dolinski, P. H. Weinreb, K. J. Simon, L. Chun Wang, D. R. Leone, R. R. Lobb, et al. {alpha}v{beta}6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse Am. J. Pathol., January 1, 2007; 170(1): 110 - 125. [Abstract] [Full Text] [PDF]

				T. M. McDevitt, L. W. Gonzales, R. C. Savani, and P. L. Ballard Role of endogenous TGF-beta in glucocorticoid-induced lung type II cell differentiation Am J Physiol Lung Cell Mol Physiol, January 1, 2007; 292(1): L249 - L257. [Abstract] [Full Text] [PDF]

				M. L. Nystrom, D. McCulloch, P. H. Weinreb, S. M. Violette, P. M. Speight, J. F. Marshall, I. R. Hart, and G. J. Thomas Cyclooxygenase-2 Inhibition Suppresses {alpha}v{beta}6 Integrin-Dependent Oral Squamous Carcinoma Invasion. Cancer Res., November 15, 2006; 66(22): 10833 - 10842. [Abstract] [Full Text] [PDF]

				K. K. Kim, M. C. Kugler, P. J. Wolters, L. Robillard, M. G. Galvez, A. N. Brumwell, D. Sheppard, and H. A. Chapman Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix PNAS, August 29, 2006; 103(35): 13180 - 13185. [Abstract] [Full Text] [PDF]

				J. K. Brown, S. M. McAleese, E. M. Thornton, J. A. Pate, A. Schock, A. I. Macrae, P. R. Scott, H. R.P. Miller, and D. D.S. Collie Integrin-{alpha}v{beta}6, a Putative Receptor for Foot-and-Mouth Disease Virus, Is Constitutively Expressed in Ruminant Airways J. Histochem. Cytochem., July 1, 2006; 54(7): 807 - 816. [Abstract] [Full Text] [PDF]

				P. Monaghan, S. Gold, J. Simpson, Z. Zhang, P. H. Weinreb, S. M. Violette, S. Alexandersen, and T. Jackson The {alpha}v{beta}6 integrin receptor for Foot-and-mouth disease virus is expressed constitutively on the epithelial cells targeted in cattle J. Gen. Virol., October 1, 2005; 86(10): 2769 - 2780. [Abstract] [Full Text] [PDF]

				J. Roux, H. Kawakatsu, B. Gartland, M. Pespeni, D. Sheppard, M. A. Matthay, C. M. Canessa, and J.-F. Pittet Interleukin-1{beta} Decreases Expression of the Epithelial Sodium Channel {alpha}-Subunit in Alveolar Epithelial Cells via a p38 MAPK-dependent Signaling Pathway J. Biol. Chem., May 13, 2005; 280(19): 18579 - 18589. [Abstract] [Full Text] [PDF]

				S. Kintarak, S. A. Whawell, P. M. Speight, S. Packer, and S. P. Nair Internalization of Staphylococcus aureus by Human Keratinocytes Infect. Immun., October 1, 2004; 72(10): 5668 - 5675. [Abstract] [Full Text] [PDF]

				S. M. Janes and F. M. Watt Switch from {alpha}v{beta}5 to {alpha}v{beta}6 integrin expression protects squamous cell carcinomas from anoikis J. Cell Biol., August 2, 2004; 166(3): 419 - 431. [Abstract] [Full Text] [PDF]

				M. R. Morgan, G. J. Thomas, A. Russell, I. R. Hart, and J. F. Marshall The Integrin Cytoplasmic-tail Motif EKQKVDLSTDC Is Sufficient to Promote Tumor Cell Invasion Mediated by Matrix Metalloproteinase (MMP)-2 or MMP-9 J. Biol. Chem., June 18, 2004; 279(25): 26533 - 26539. [Abstract] [Full Text] [PDF]

				A. LEASK and D. J. ABRAHAM TGF-{beta} signaling and the fibrotic response FASEB J, May 1, 2004; 18(7): 816 - 827. [Abstract] [Full Text] [PDF]

				P. H. Weinreb, K. J. Simon, P. Rayhorn, W. J. Yang, D. R. Leone, B. M. Dolinski, B. R. Pearse, Y. Yokota, H. Kawakatsu, A. Atakilit, et al. Function-blocking Integrin {alpha}v{beta}6 Monoclonal Antibodies: DISTINCT LIGAND-MIMETIC AND NONLIGAND-MIMETIC CLASSES J. Biol. Chem., April 23, 2004; 279(17): 17875 - 17887. [Abstract] [Full Text] [PDF]

				L. Hakkinen, L. Koivisto, H. Gardner, U. Saarialho-Kere, J. M. Carroll, M. Lakso, H. Rauvala, M. Laato, J. Heino, and H. Larjava Increased Expression of {beta}6-Integrin in Skin Leads to Spontaneous Development of Chronic Wounds Am. J. Pathol., January 1, 2004; 164(1): 229 - 242. [Abstract] [Full Text] [PDF]

				X. Li, Y. Yang, Y. Hu, D. Dang, J. Regezi, B. L. Schmidt, A. Atakilit, B. Chen, D. Ellis, and D. M. Ramos {alpha}v{beta}6-Fyn Signaling Promotes Oral Cancer Progression J. Biol. Chem., October 24, 2003; 278(43): 41646 - 41653. [Abstract] [Full Text] [PDF]

				L.-J. Ma, H. Yang, A. Gaspert, G. Carlesso, M. M. Barty, J. M. Davidson, D. Sheppard, and A. B. Fogo Transforming Growth Factor-{beta}-Dependent and -Independent Pathways of Induction of Tubulointerstitial Fibrosis in {beta}6-/- Mice Am. J. Pathol., October 1, 2003; 163(4): 1261 - 1273. [Abstract] [Full Text] [PDF]

				L. Fjellbirkeland, S. Cambier, V. C. Broaddus, A. Hill, P. Brunetta, G. Dolganov, D. Jablons, and S. L. Nishimura Integrin {alpha}v{beta}8-Mediated Activation of Transforming Growth Factor-{beta} Inhibits Human Airway Epithelial Proliferation in Intact Bronchial Tissue Am. J. Pathol., August 1, 2003; 163(2): 533 - 542. [Abstract] [Full Text] [PDF]

				D. SHEPPARD Functions of Pulmonary Epithelial Integrins: From Development to Disease Physiol Rev, July 1, 2003; 83(3): 673 - 686. [Abstract] [Full Text] [PDF]

				R. J. Fahy, F. Lichtenberger, C. B. McKeegan, G. J. Nuovo, C. B. Marsh, and M. D. Wewers The Acute Respiratory Distress Syndrome: A Role for Transforming Growth Factor-{beta}1 Am. J. Respir. Cell Mol. Biol., April 1, 2003; 28(4): 499 - 503. [Abstract] [Full Text] [PDF]

				P. A. Nony and R. G. Schnellmann Mechanisms of Renal Cell Repair and Regeneration after Acute Renal Failure J. Pharmacol. Exp. Ther., March 1, 2003; 304(3): 905 - 912. [Abstract] [Full Text] [PDF]

				H. Duque and B. Baxt Foot-and-Mouth Disease Virus Receptors: Comparison of Bovine {alpha}V Integrin Utilization by Type A and O Viruses J. Virol., February 15, 2003; 77(4): 2500 - 2511. [Abstract] [Full Text] [PDF]