Galectin-3 expression and effects on cyst enlargement and tubulogenesis in kidney epithelial MDCK cells cultured in three-dimensional matrices in vitro

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Bao, Q.
	Articles by Hughes, R. C.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Bao, Q.
	Articles by Hughes, R. C.


Social Bookmarking

	What's this?

Barondes, S. H., Castronovo, V., Cooper, D. N. W., Cummings, R. D., Drickamer, K., Feizi, T., Gitt, M. A., Hirabayashi, J., Hughes, C., Kasai, K., Leffler, H., Liu, F. T., Lotan, R., Mercurio, A. M., Monsigny, M., Pillai, S., Poirer, F., Raz, A., Rigby, P. W. J., Rini, J. M. and Wang, J. L (1994). Galectins: a family of animalgalactoside-binding lectins. Cell 76, 597-598.[Medline]

Chiquet-Ehrismann, R (1991). Anti-adhesive molecules of the extracellular matrix. Curr. Opin. Cell Biol 3, 800-804.[Medline]

Chiu, M. L., Parry, D. A. D., Feldman, S. R., Klapper, D. G. and O'Keefe, E. J (1994). An adherins junction protein is a member of the family of lactose-binding lectins. J. Biol. Chem 269, 31770-31776.[Abstract/Free Full Text]

Cooper, D. N., Massa, S. M. and Barondes, S. H (1991). Endogenous muscle lectin inhibits myoblast adhesion to laminin. J. Cell Biol 115, 1437-1448.[Abstract/Free Full Text]

Ekblom, P., Lash, J. W., Lehtonen, E., Nordling, S. and Saxen, L (1979). Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON). Exp. Cell Res 121, 121-126.[Medline]

Ekblom, P., Nordling, S., Saxen, L., Rasilo, M-L. and Renkonen, O (1979). Cell interactions leading to kidney tubule determination are tunicamycin-sensitive. Cell Differ 8, 347-352.[Medline]

Foddy, L., Stamatoglou, S. C. and Hughes, R. C (1990). An endogenous carbohydrate-binding protein of baby hamster kidney (BHK21 C13) cells. Temporal changes in cellular expression in the developing kidney. J. Cell Sci 97, 139-148.[Abstract/Free Full Text]

Gottari, C. and Caplan,M. J (1993). Delivery of Na+,K+-ATPase in polarized epithelial cells. Science 260, 552-554.[Free Full Text]

Gu, M., Wang, W., Song, W. K., Cooper, D. N. and Kaufman, S. J (1994). Selective modulation of the interaction of 71 integrin with fibronectin and laminin by L-14 lectin during skeletal muscle differentiation. J. Cell Sci 107, 175-181.[Abstract]

Hammerton, R. W., Krzeminski, K. A., Mays, R. W., Ryan, T. A., Wollner, D. A. and Nelson, W. J (1991). Mechanism for regulating cell surface distribution of Na+,K+-ATPase in polarized epithelial cells. Science 254, 847-850.[Abstract/Free Full Text]

Holth\232fer, H (1988). Cell-type-specific glycoconjugates of collecting duct cells during maturation of the rat kidney. Cell Tiss. Res 253, 305-309.[Medline]

Hsu, D. K., Zuberi, R. I. and Liu, F. T (1992). Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin. J. Biol. Chem 267, 14167-14174.[Abstract/Free Full Text]

Hughes, R. C (1992). Lectins as cell adhesion molecules. Curr. Opin. Struct. Biol 2, 687-692.

Hughes, R. C (1994). Mac 2: a versatile galactose-binding protein of mammalian tissues. Glycobiology 4, 5-12.[Abstract/Free Full Text]

Humes, H. D. and Cieslinski, D. A (1992). Interaction between growth factors and retinoid acid in the induction of kidney tubulogenesis in tissue culture. Exp. Cell Res 201, 8-15.[Medline]

Inohara, H. and Raz, A (1994). Effects of natural complex carbohydrates on murine melanoma cell properties related to galectin 3 functions. Glycocon. J 11, 527-532.[Medline]

Keizer, G. D., Visser, W., Vliem M. and Figdor, C. G (1988). A monoclonal antibody directed against a unique epitope on the-chain of human leukocyte function-associated antigen-1 induces homotypic cell-cell interactions. J. Immunol 140, 1393-1400.[Abstract]

Laitinen, L., Virtanen, I. and Saxen, L (1987). Changes in the glycosylation pattern during embryonic development of mouse kidney as revealed with lectin conjugates. J. Histochem. Cytochem 35, 55-65.[Abstract]

Landis, R. C., Bennett, R. I. and Hogg, N (1993). A novel LFA-1activation epitope maps to the I domain. J. Cell Biol 120, 1519-1529.[Abstract/Free Full Text]

Lane, T. F. and Sage, E. H (1994). The biology of SPARC, a protein that modulates cell-matrix interactions. FASEB J 8, 163-173.[Abstract]

Lindstedt, R., Apodaca, G., Barondes, S. H., Mostov, K. E. and Leffler, H (1993). Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway. J. Biol. Chem 268, 11750-11757.[Abstract/Free Full Text]

Lotan, R., Belloni, P. N., Tressler, R. J., Lotan, D., Chun, X. X. and Nicolson, G. L (1994). Expression of galectins on microvessel endothelial cells and their involvement in tumour cell adhesion. Glycocon. J 11, 462-468.[Medline]

Mahanthappa, N. K., Cooper, D. N., Barondes, S. H. and Schwarting, G. A (1994). Rat olfactory neurons can utilize the endogenous lectin, L-14, in a novel adhesion mechanism. Development 120, 1373-1384.[Abstract]

Massa, S. M., Cooper, D. N., Leffler, H. and Barondes, S. H (1993). L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity. Biochemistry 32, 260-267.[Medline]

McAteer, T. A., Evan, A. P. and Gardner K. D (1987). Morphogenic clonal growth of kidney epithelial cell line MDCK. Anat. Rec 217, 229-239.[Medline]

Mehul, B., Bawumia, S., Martin, S. R. and Hughes, R. C (1994). Structure of baby hamster kidney carbohydrate-binding protein CBP30, an S-type animal lectin. J. Biol. Chem 269, 18250-18258.[Abstract/Free Full Text]

Mehul, B., Bawumia, S. and Hughes, R. C (1995). Cross-linking of galectin-3, a galactose-binding protein of mammalian cells by tissue-type transglutaminase. FEBS Lett 360, 160-164.[Medline]

Milos, N. and Zalik, S. E (1983). Calcium-independent adhesion of extra-embryonic endoderm cells from the early chick blastoderm is inhibited by the blastoderm-galactoside-binding lectin and by -galactosidase. Cell Differ 12, 341-347.[Medline]

Montesano, R., Schaller, G and Orci, L (1991). Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell 66, 697-711.[Medline]

Montesano, R., Matsumoto, K., Nakamura, T. and Orci, L (1991). Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 67, 901-908.[Medline]

Nelson, W. J. and Hammerton, R. W (1989). A membrane-cytoskeletalcomplex containing Na+, K+-ATPase, ankyrin, and fodrin in Madin-Darby canine kidney (MDCK) cells: implications for the biogenesis of epithelial cell polarity. J. Cell Biol 108, 893-902.[Abstract/Free Full Text]

Nelson, W. J., Shore, E. M., Wang, A. Z. and Hammerton, R. W (1990). Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin), ankyrin, and fodrin in Madin-Darby canine kidney epithelial cells. J. Cell Biol 110, 349-357.[Abstract/Free Full Text]

Ochieng, J., Platt, D., Tait, L., Hogan, V., Raz, T., Carmi, P. and Raz, A (1993). Structure-function relationship of a recombinant human galactoside-binding protein. Biochemistry 32, 4455-4460.[Medline]

Ojakian, G. K. and Schwimmer, R (1988). The polarized distribution of an apical cell surface glycoprotein is maintained by interactions with the cytoskeleton of Mardin-Derby canine kidney cells. J. Cell Biol 107, 2377-2388.[Abstract/Free Full Text]

Santos, O. F. and Nigam, S. K (1993). HGF-induced tubulogenesis and branching of epithelial cells is modulated by extracellular matrix and TGF-. Dev. Biol 160, 293-302.[Medline]

Sato, S. and Hughes, R. C (1992). Binding specificity of a baby hamster kidney lectin for H type I and II chains, polylactosamine glycans, and appropriately glycosylated forms of laminin and fibronectin. J. Biol. Chem 267, 6983-6990.[Abstract/Free Full Text]

Sato, S., Burdett, I. and Hughes, R. C (1993). Secretion of the baby hamster kidney 30-kDa galactose-binding lectin from polarized and nonpolarized cells: a pathway independent of the endoplasmic reticulum-Golgi complex. Exp. Cell Res 207, 8-18.[Medline]

Simons, K. and Fuller, S. D (1985). Cell surface polarity in epithelia. Annu. Rev. Cell Biol 1, 243-288.

Taub, M., Wang, Y., Szczesny, T. M. and Kleinman, H. K (1990). Epidermal growth factor or transforming growth factoris required for kidney tubulogenesis in matrigel cultures in serum-free medium. Proc. Nat. Acad. Sci. USA 87, 4002-4006.[Abstract/Free Full Text]

van Adelsberg, J., Edwards, J. C., Takito, J., Kiss, B. and Al-Awqati, Q (1994). An induced extracellular matrix protein reverses the polarity of band 3 in intercalated epithelial cells. Cell 76, 1053-1061.[Medline]

van Kooyk, Y., Weder, P., Hogervorst, F., Verhoeven, A. J., van Seventer, G., te Velde, A. A., Borst, J., Keizer, G. D. and Figdor, C. G (1991). Activation of LFA-1 through a Ca2+-dependent epitope stimulates lymphocyte adhesion. J. Cell Biol 112, 345-354.[Abstract/Free Full Text]

Wang, A. Z., Ojakian, G. K. and Nelson, W. J (1990). Steps in the morphogenesis of a polarized epithelium. I. Uncoupling the roles of cell-cell and cell-substratum contact in establishing plasma membrane polarity in multicellular epithelial (MDCK) cysts. J. Cell Sci 95, 137-151.[Abstract/Free Full Text]

Wang, A. Z., Ojakian, G. K. and Nelson, W. J (1990). Steps in the morphogenesis of a polarized epithelium. II. Disassembly and assembly of plasma membrane domains during reversal of epithelial cell polarity in multicellular epithelial (MDCK) cysts. J. Cell Sci 95, 153-165.[Abstract/Free Full Text]

Woynarowska, B., Skrincosky, D. M., Haag, A., Sharma, M., Matta, K. and Bernacki, R. J (1994). Inhibition of lectin-mediated ovarian tumor cell adhesion by sugar analogs. J. Biol. Chem 269, 22797-23803.[Abstract/Free Full Text]

Yamashita, K., Totani, K., Ohkura, T., Takasaki, S., Goldstein, I. J. and Kobata, A (1987). Carbohydrate binding properties of complex-type oligosaccharides on immobilized Datura stramonium Lectin. J. Biol. Chem 262, 1602-1607.[Abstract/Free Full Text]

Zhou, Q. and Cummings, R. D (1993). L-14 lectin recognition of laminin and its promotion of in vitro cell adhesion. Arch. Biochem. Biophys 300, 6-17.[Medline]

Zurzolo, C. and Rodriguez-Boulan, E (1993). Delivery of Na+K+ATPase in polarized epithelial cells. Science 260, 550-552.[Free Full Text]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

C.-X. Lei, W. Zhang, J.-P. Zhou, and Y.-K. Liu
Interactions between galectin-3 and integrin{beta}3 in regulating endometrial cell proliferation and adhesion
Hum. Reprod., November 1, 2009; 24(11): 2879 - 2889.
[Abstract] [Full Text] [PDF]

J. M. Torkko, A. Manninen, S. Schuck, and K. Simons
Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis
J. Cell Sci., April 15, 2008; 121(8): 1193 - 1203.
[Abstract] [Full Text] [PDF]

C Boileau, F Poirier, J-P Pelletier, M Guevremont, N Duval, J Martel-Pelletier, and P Reboul
Intracellular localisation of galectin-3 has a protective role in chondrocyte survival
Ann Rheum Dis, February 1, 2008; 67(2): 175 - 181.
[Abstract] [Full Text] [PDF]

J. Friedrichs, J. M. Torkko, J. Helenius, T. P. Teravainen, J. Fullekrug, D. J. Muller, K. Simons, and A. Manninen
Contributions of Galectin-3 and -9 to Epithelial Cell Adhesion Analyzed by Single Cell Force Spectroscopy
J. Biol. Chem., October 5, 2007; 282(40): 29375 - 29383.
[Abstract] [Full Text] [PDF]

J. Nio and T. Iwanaga
Galectins in the Mouse Ovary: Concomitant Expression of Galectin-3 and Progesterone Degradation Enzyme (20{alpha}-HSD) in the Corpus Luteum
J. Histochem. Cytochem., May 1, 2007; 55(5): 423 - 432.
[Abstract] [Full Text] [PDF]

M. G. Chiu, T. M. Johnson, A. S. Woolf, E. M. Dahm-Vicker, D. A. Long, L. Guay-Woodford, K. A. Hillman, S. Bawumia, K. Venner, R. C. Hughes, et al.
Galectin-3 Associates with the Primary Cilium and Modulates Cyst Growth in Congenital Polycystic Kidney Disease
Am. J. Pathol., December 1, 2006; 169(6): 1925 - 1938.
[Abstract] [Full Text] [PDF]

L. Battini, E. Fedorova, S. Macip, X. Li, P. D. Wilson, and G. L. Gusella
Stable Knockdown of Polycystin-1 Confers Integrin-{alpha}2beta1-Mediated Anoikis Resistance
J. Am. Soc. Nephrol., November 1, 2006; 17(11): 3049 - 3058.
[Abstract] [Full Text] [PDF]

M Guevremont, J Martel-Pelletier, C Boileau, F-T Liu, M Richard, J-C Fernandes, J-P Pelletier, and P Reboul
Galectin-3 surface expression on human adult chondrocytes: a potential substrate for collagenase-3
Ann Rheum Dis, June 1, 2004; 63(6): 636 - 643.
[Abstract] [Full Text]

N. Ahmad, H.-J. Gabius, S. Andre, H. Kaltner, S. Sabesan, R. Roy, B. Liu, F. Macaluso, and C. F. Brewer
Galectin-3 Precipitates as a Pentamer with Synthetic Multivalent Carbohydrates and Forms Heterogeneous Cross-linked Complexes
J. Biol. Chem., March 19, 2004; 279(12): 10841 - 10847.
[Abstract] [Full Text] [PDF]

Y. Kikuchi, S. Kobayashi, N. Hemmi, R. Ikee, N. Hyodo, T. Saigusa, T. Namikoshi, M. Yamada, S. Suzuki, and S. Miura
Galectin-3-positive cell infiltration in human diabetic nephropathy
Nephrol. Dial. Transplant., March 1, 2004; 19(3): 602 - 607.
[Abstract] [Full Text] [PDF]

E. Provost, Y. Yamamoto, I. Lizardi, J. Stern, T. G. D'Aquila, R. B. Gaynor, and D. L. Rimm
Functional Correlates of Mutations in {beta}-Catenin Exon 3 Phosphorylation Sites
J. Biol. Chem., August 22, 2003; 278(34): 31781 - 31789.
[Abstract] [Full Text] [PDF]

M. Stock, H. Schafer, S. Stricker, G. Gross, S. Mundlos, and F. Otto
Expression of Galectin-3 in Skeletal Tissues Is Controlled by Runx2
J. Biol. Chem., May 2, 2003; 278(19): 17360 - 17367.
[Abstract] [Full Text] [PDF]

J. H. Wright, X. Wang, G. Manning, B. J. LaMere, P. Le, S. Zhu, D. Khatry, P. M. Flanagan, S. D. Buckley, D. B. Whyte, et al.
The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion
Mol. Cell. Biol., March 15, 2003; 23(6): 2068 - 2082.
[Abstract] [Full Text] [PDF]

T. Shimamura, M. Sakamoto, Y. Ino, K. Shimada, T. Kosuge, Y. Sato, K. Tanaka, H. Sekihara, and S. Hirohashi
Clinicopathological Significance of Galectin-3 Expression in Ductal Adenocarcinoma of the Pancreas
Clin. Cancer Res., August 1, 2002; 8(8): 2570 - 2575.
[Abstract] [Full Text] [PDF]

B.-K. Moon, Y. J. Lee, P. Battle, J. M. Jessup, A. Raz, and H.-R. C. Kim
Galectin-3 Protects Human Breast Carcinoma Cells against Nitric Oxide-Induced Apoptosis : Implication of Galectin-3 Function during Metastasis
Am. J. Pathol., September 1, 2001; 159(3): 1055 - 1060.
[Abstract] [Full Text] [PDF]

S. L. BULLOCK, T. M. JOHNSON, Q. BAO, R. C. HUGHES, P. J. D. WINYARD, and A. S. WOOLF
Galectin-3 Modulates Ureteric Bud Branching in Organ Culture of the Developing Mouse Kidney
J. Am. Soc. Nephrol., March 1, 2001; 12(3): 515 - 523.
[Abstract] [Full Text]

C. Hikita, S. Vijayakumar, J. Takito, H. Erdjument-Bromage, P. Tempst, and Q. Al-Awqati
Induction of Terminal Differentiation in Epithelial Cells Requires Polymerization of Hensin by Galectin 3
J. Cell Biol., December 11, 2000; 151(6): 1235 - 1246.
[Abstract] [Full Text] [PDF]

J. H. Lipschutz, W. Guo, L. E. O'Brien, Y. H. Nguyen, P. Novick, and K. E. Mostov
Exocyst Is Involved in Cystogenesis and Tubulogenesis and Acts by Modulating Synthesis and Delivery of Basolateral Plasma Membrane and Secretory Proteins
Mol. Biol. Cell, December 1, 2000; 11(12): 4259 - 4275.
[Abstract] [Full Text]

J. Nishiyama, S. Kobayashi, A. Ishida, I. Nakabayashi, O. Tajima, S. Miura, M. Katayama, and H. Nogami
Up-Regulation of Galectin-3 in Acute Renal Failure of the Rat
Am. J. Pathol., September 1, 2000; 157(3): 815 - 823.
[Abstract] [Full Text] [PDF]

D. K. Hsu, R.-Y. Yang, Z. Pan, L. Yu, D. R. Salomon, W.-P. Fung-Leung, and F.-T. Liu
Targeted Disruption of the Galectin-3 Gene Results in Attenuated Peritoneal Inflammatory Responses
Am. J. Pathol., March 1, 2000; 156(3): 1073 - 1083.
[Abstract] [Full Text] [PDF]

F. Bernerd, A. Sarasin, and T. Magnaldo
Galectin-7 overexpression is associated with the apoptotic process in UVB-induced sunburn keratinocytes
PNAS, September 28, 1999; 96(20): 11329 - 11334.
[Abstract] [Full Text] [PDF]

J. Seetharaman, A. Kanigsberg, R. Slaaby, H. Leffler, S. H. Barondes, and J. M. Rini
X-ray Crystal Structure of the Human Galectin-3 Carbohydrate Recognition Domain at 2.1-A Resolution
J. Biol. Chem., May 22, 1998; 273(21): 13047 - 13052.
[Abstract] [Full Text] [PDF]

B Mehul and R. Hughes
Plasma membrane targetting, vesicular budding and release of galectin 3 from the cytoplasm of mammalian cells during secretion
J. Cell Sci., January 5, 1997; 110(10): 1169 - 1178.
[Abstract] [PDF]

M. Guittaut, S. Charpentier, T. Normand, M. Dubois, J. Raimond, and A. Legrand
Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3
J. Biol. Chem., January 19, 2001; 276(4): 2652 - 2657.
[Abstract] [Full Text] [PDF]

N. Mazurek, J. Conklin, J. C. Byrd, A. Raz, and R. S. Bresalier
Phosphorylation of the beta -Galactoside-binding Protein Galectin-3 Modulates Binding to Its Ligands
J. Biol. Chem., November 10, 2000; 275(46): 36311 - 36315.
[Abstract] [Full Text] [PDF]

J. Kopitz, C. von Reitzenstein, S. Andre, H. Kaltner, J. Uhl, V. Ehemann, M. Cantz, and H.-J. Gabius
Negative Regulation of Neuroblastoma Cell Growth by Carbohydrate-dependent Surface Binding of Galectin-1 and Functional Divergence from Galectin-3
J. Biol. Chem., September 14, 2001; 276(38): 35917 - 35923.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Bao, Q.

Articles by Hughes, R. C.

Search for Related Content

PubMed

PubMed Citation

Articles by Bao, Q.

Articles by Hughes, R. C.

Social Bookmarking

What's this?

				J. M. Torkko, A. Manninen, S. Schuck, and K. Simons Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis J. Cell Sci., April 15, 2008; 121(8): 1193 - 1203. [Abstract] [Full Text] [PDF]

				C Boileau, F Poirier, J-P Pelletier, M Guevremont, N Duval, J Martel-Pelletier, and P Reboul Intracellular localisation of galectin-3 has a protective role in chondrocyte survival Ann Rheum Dis, February 1, 2008; 67(2): 175 - 181. [Abstract] [Full Text] [PDF]

				J. Friedrichs, J. M. Torkko, J. Helenius, T. P. Teravainen, J. Fullekrug, D. J. Muller, K. Simons, and A. Manninen Contributions of Galectin-3 and -9 to Epithelial Cell Adhesion Analyzed by Single Cell Force Spectroscopy J. Biol. Chem., October 5, 2007; 282(40): 29375 - 29383. [Abstract] [Full Text] [PDF]

				J. Nio and T. Iwanaga Galectins in the Mouse Ovary: Concomitant Expression of Galectin-3 and Progesterone Degradation Enzyme (20{alpha}-HSD) in the Corpus Luteum J. Histochem. Cytochem., May 1, 2007; 55(5): 423 - 432. [Abstract] [Full Text] [PDF]

				M. G. Chiu, T. M. Johnson, A. S. Woolf, E. M. Dahm-Vicker, D. A. Long, L. Guay-Woodford, K. A. Hillman, S. Bawumia, K. Venner, R. C. Hughes, et al. Galectin-3 Associates with the Primary Cilium and Modulates Cyst Growth in Congenital Polycystic Kidney Disease Am. J. Pathol., December 1, 2006; 169(6): 1925 - 1938. [Abstract] [Full Text] [PDF]

				L. Battini, E. Fedorova, S. Macip, X. Li, P. D. Wilson, and G. L. Gusella Stable Knockdown of Polycystin-1 Confers Integrin-{alpha}2beta1-Mediated Anoikis Resistance J. Am. Soc. Nephrol., November 1, 2006; 17(11): 3049 - 3058. [Abstract] [Full Text] [PDF]

				M Guevremont, J Martel-Pelletier, C Boileau, F-T Liu, M Richard, J-C Fernandes, J-P Pelletier, and P Reboul Galectin-3 surface expression on human adult chondrocytes: a potential substrate for collagenase-3 Ann Rheum Dis, June 1, 2004; 63(6): 636 - 643. [Abstract] [Full Text]

				N. Ahmad, H.-J. Gabius, S. Andre, H. Kaltner, S. Sabesan, R. Roy, B. Liu, F. Macaluso, and C. F. Brewer Galectin-3 Precipitates as a Pentamer with Synthetic Multivalent Carbohydrates and Forms Heterogeneous Cross-linked Complexes J. Biol. Chem., March 19, 2004; 279(12): 10841 - 10847. [Abstract] [Full Text] [PDF]

				Y. Kikuchi, S. Kobayashi, N. Hemmi, R. Ikee, N. Hyodo, T. Saigusa, T. Namikoshi, M. Yamada, S. Suzuki, and S. Miura Galectin-3-positive cell infiltration in human diabetic nephropathy Nephrol. Dial. Transplant., March 1, 2004; 19(3): 602 - 607. [Abstract] [Full Text] [PDF]

				E. Provost, Y. Yamamoto, I. Lizardi, J. Stern, T. G. D'Aquila, R. B. Gaynor, and D. L. Rimm Functional Correlates of Mutations in {beta}-Catenin Exon 3 Phosphorylation Sites J. Biol. Chem., August 22, 2003; 278(34): 31781 - 31789. [Abstract] [Full Text] [PDF]

				M. Stock, H. Schafer, S. Stricker, G. Gross, S. Mundlos, and F. Otto Expression of Galectin-3 in Skeletal Tissues Is Controlled by Runx2 J. Biol. Chem., May 2, 2003; 278(19): 17360 - 17367. [Abstract] [Full Text] [PDF]

				J. H. Wright, X. Wang, G. Manning, B. J. LaMere, P. Le, S. Zhu, D. Khatry, P. M. Flanagan, S. D. Buckley, D. B. Whyte, et al. The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion Mol. Cell. Biol., March 15, 2003; 23(6): 2068 - 2082. [Abstract] [Full Text] [PDF]

				T. Shimamura, M. Sakamoto, Y. Ino, K. Shimada, T. Kosuge, Y. Sato, K. Tanaka, H. Sekihara, and S. Hirohashi Clinicopathological Significance of Galectin-3 Expression in Ductal Adenocarcinoma of the Pancreas Clin. Cancer Res., August 1, 2002; 8(8): 2570 - 2575. [Abstract] [Full Text] [PDF]

				B.-K. Moon, Y. J. Lee, P. Battle, J. M. Jessup, A. Raz, and H.-R. C. Kim Galectin-3 Protects Human Breast Carcinoma Cells against Nitric Oxide-Induced Apoptosis : Implication of Galectin-3 Function during Metastasis Am. J. Pathol., September 1, 2001; 159(3): 1055 - 1060. [Abstract] [Full Text] [PDF]

				S. L. BULLOCK, T. M. JOHNSON, Q. BAO, R. C. HUGHES, P. J. D. WINYARD, and A. S. WOOLF Galectin-3 Modulates Ureteric Bud Branching in Organ Culture of the Developing Mouse Kidney J. Am. Soc. Nephrol., March 1, 2001; 12(3): 515 - 523. [Abstract] [Full Text]

				C. Hikita, S. Vijayakumar, J. Takito, H. Erdjument-Bromage, P. Tempst, and Q. Al-Awqati Induction of Terminal Differentiation in Epithelial Cells Requires Polymerization of Hensin by Galectin 3 J. Cell Biol., December 11, 2000; 151(6): 1235 - 1246. [Abstract] [Full Text] [PDF]

				J. H. Lipschutz, W. Guo, L. E. O'Brien, Y. H. Nguyen, P. Novick, and K. E. Mostov Exocyst Is Involved in Cystogenesis and Tubulogenesis and Acts by Modulating Synthesis and Delivery of Basolateral Plasma Membrane and Secretory Proteins Mol. Biol. Cell, December 1, 2000; 11(12): 4259 - 4275. [Abstract] [Full Text]

				J. Nishiyama, S. Kobayashi, A. Ishida, I. Nakabayashi, O. Tajima, S. Miura, M. Katayama, and H. Nogami Up-Regulation of Galectin-3 in Acute Renal Failure of the Rat Am. J. Pathol., September 1, 2000; 157(3): 815 - 823. [Abstract] [Full Text] [PDF]

				D. K. Hsu, R.-Y. Yang, Z. Pan, L. Yu, D. R. Salomon, W.-P. Fung-Leung, and F.-T. Liu Targeted Disruption of the Galectin-3 Gene Results in Attenuated Peritoneal Inflammatory Responses Am. J. Pathol., March 1, 2000; 156(3): 1073 - 1083. [Abstract] [Full Text] [PDF]

				F. Bernerd, A. Sarasin, and T. Magnaldo Galectin-7 overexpression is associated with the apoptotic process in UVB-induced sunburn keratinocytes PNAS, September 28, 1999; 96(20): 11329 - 11334. [Abstract] [Full Text] [PDF]

				J. Seetharaman, A. Kanigsberg, R. Slaaby, H. Leffler, S. H. Barondes, and J. M. Rini X-ray Crystal Structure of the Human Galectin-3 Carbohydrate Recognition Domain at 2.1-A Resolution J. Biol. Chem., May 22, 1998; 273(21): 13047 - 13052. [Abstract] [Full Text] [PDF]

				B Mehul and R. Hughes Plasma membrane targetting, vesicular budding and release of galectin 3 from the cytoplasm of mammalian cells during secretion J. Cell Sci., January 5, 1997; 110(10): 1169 - 1178. [Abstract] [PDF]

				M. Guittaut, S. Charpentier, T. Normand, M. Dubois, J. Raimond, and A. Legrand Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3 J. Biol. Chem., January 19, 2001; 276(4): 2652 - 2657. [Abstract] [Full Text] [PDF]

				N. Mazurek, J. Conklin, J. C. Byrd, A. Raz, and R. S. Bresalier Phosphorylation of the beta -Galactoside-binding Protein Galectin-3 Modulates Binding to Its Ligands J. Biol. Chem., November 10, 2000; 275(46): 36311 - 36315. [Abstract] [Full Text] [PDF]

				J. Kopitz, C. von Reitzenstein, S. Andre, H. Kaltner, J. Uhl, V. Ehemann, M. Cantz, and H.-J. Gabius Negative Regulation of Neuroblastoma Cell Growth by Carbohydrate-dependent Surface Binding of Galectin-1 and Functional Divergence from Galectin-3 J. Biol. Chem., September 14, 2001; 276(38): 35917 - 35923. [Abstract] [Full Text] [PDF]