An anti-alpha v-integrin antibody that blocks integrin function inhibits the development of a human melanoma in nude mice

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Albelda, S. M., Mette, S. A., Elder, D. E., Stewart, R., Damjanovich, L., Herlyn, M. and Buck, C. A (1990). Integrin distribution in malignantmelanoma: association of the beta 3 subunit with tumor progression. Cancer Res 50, 6757-6764.[Abstract/Free Full Text]

Brooks, P. C., Clark, R. A. and Cheresh, D. A (1994). Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 264, 569-571.[Abstract/Free Full Text]

Brooks, P. C., Montgomery, A. M. P., Rosenfeld, M., Reisfeld, R. A., Hu, T., Klier, G. and Cheresh, D. A (1994). Integrin3 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79, 1157-1164.[Medline]

Buck, C., Albelda, S., Damjanovich, L., Edelman, J., Shih, D. T. and Solowska, J (1990). Immunohistochemical and molecular analysis of beta 1 and beta 3 integrins. Cell Diff. Dev 32, 189-202.[Medline]

Busk, M., Pytela, R. and Sheppard, D (1992). Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein. J. Biol. Chem 267, 5790-5796.[Abstract/Free Full Text]

Carter, W. G., Wayner, E. A., Bouchard, T. S. and Kaur, P (1990). The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells. J. Cell Biol 110, 1387-1404.[Abstract/Free Full Text]

Chan, B. M. and Hemler, M. E (1993). Multiple functional forms of the integrin VLA-2 can be derived from a single alpha 2 cDNA clone: interconversion of forms induced by an anti-beta 1 antibody. J. Cell Biol 120, 537-543.[Abstract/Free Full Text]

Charo, I. F., Nannizzi, L., Smith, J. W. and Cheresh, D. A (1990). The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin. J. Cell Biol 111, 2795-2800.[Abstract/Free Full Text]

Cheng, Y. F., Clyman, R. I., Enenstein, J., Waleh, N., Pytela, R. and Kramer, R. H (1991). The integrin complex alpha v beta 3 participates in the adhesion of microvascular endothelial cells to fibronectin. Exp. Cell Res 194, 69-77.[Medline]

Cheresh, D. A. and Harper, J. R (1987). Arg-Gly-Asp recognition by a cell adhesion receptor requires its 130-kDa alpha subunit. J. Biol. Chem 262, 1434-1437.[Abstract/Free Full Text]

Cheresh, D. A. and Spiro, R. C (1987). Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor. J. Biol. Chem 262, 17703-17711.[Abstract/Free Full Text]

Cheresh, D. A., Pytela, R., Pierschbacher, M. D., Klier, F. G., Ruoslahti, E. and Reisfeld, R. A (1987). An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in a divalent cation-dependent functional complex with the disialoganglioside GD2. J. Cell Biol 105, 1163-1173.[Abstract/Free Full Text]

Cheresh, D. A., Smith, J. W., Cooper, H. M. and Quaranta, V (1989). A novel vitronectin receptor integrin (alpha v beta x) is responsible for distinct adhesive properties of carcinoma cells. Cell 57, 59-69.[Medline]

Cheresh, D. A (1991). Structure, function and biological properties of integrin alpha v beta 3 on human melanoma cells. Cancer Metast. Rev 10, 3-10.[Medline]

Chuntharapai, A., Bodary, S., Horton, M. and Kim, K. J (1993). Blocking monoclonal antibodies to alpha V beta 3 integrin: a unique epitope of alpha V beta 3 integrin is present on human osteoclasts. Exp. Cell Res 205, 345-352.[Medline]

Danen, E. H., van Muijen, G. N., van de Wiel van Kemenade, E., Jansen, K. F., Ruiter, D. J. and Figdor, C. G (1993). Regulation of integrin-mediated adhesion to laminin and collagen in human melanocytes and in non-metastatic and highly metastatic human melanoma cells. Int. J. Cancer 54, 315-321.[Medline]

Davies, J., Warwick, J., Totty, N., Philp, R., Helfrich, M. and Horton, M (1989). The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor. J. Cell Biol 109, 1817-1826.[Abstract/Free Full Text]

de Boer, H. C., de Groot, P. G., Bouma, B. N. and Preissner, K. T (1993). Ternary vitronectin-thrombin-antithrombin III complexes in human plasma. Detection and mode of association. J. Biol. Chem 268, 1279-1283.[Abstract/Free Full Text]

Delwel, G. O., Hogervorst, F., Kuikman, I., Paulsson, M., Timpl, R. and Sonnenberg, A (1993). Expression and function of the cytoplasmic variants of the integrin alpha 6 subunit in transfected K562 cells. Activation-dependent adhesion and interaction with isoforms of laminin. J. Biol. Chem 268, 25865-25875.[Abstract/Free Full Text]

Denhardt, D. T. and Guo, X (1993). Osteopontin: a protein with diverse functions. FASEB J 7, 1475-1482.[Abstract]

Diamond, M. S. and Springer, T. A (1994). The dynamic regulation of integrin adhesiveness. Curr. Biol 4, 506-517.[Medline]

Etoh, T., Byers, H. R. and Mihm, M. C. J (1992). Integrin expression in malignant melanoma and their role in cell attachment and migration on extracellular matrix proteins. J. Dermatol 19, 841-846.[Medline]

D. A (1992). Involvement of integrin alpha V gene expression in human melanoma tumorigenicity. J. Clin. Invest 89, 2018-2022.

Fidler, I. J (1988). Origin of cancer metastases and its implications for therapy. Isr. J. Med. Sci 24, 456-463.[Medline]

Furihata, K., Nugent, D. J., Bissonette, A., Aster, R. H. and Kunicki, T. J (1987). On the association of the platelet-specific alloantigen, Pena, with glycoprotein IIIa. Evidence for heterogeneity of glycoprotein IIIa. J. Clin. Invest 80, 1624-1630.

Gehlsen, K. R., Davis, G. E. and Sriramarao, P (1992). Integrin expression in human melanoma cells with differing invasive and metastatic properties. Clin. Exp. Metast 10, 111-120.[Medline]

Goodman, S. L., Aumailley, M. and von der Mark, H (1991). Multiple cell surface receptors for the short arms of laminin: alpha11 integrin and RGD-dependent proteins mediate cell attachment only to domains III in murine tumour laminin. J. Cell Biol 113, 931-941.[Abstract/Free Full Text]

Haba, S., Ovary, Z. and Nisonoff, A (1985). Clearance of IgE from serum of normal and hybridoma-bearing mice. J. Immunol 134, 3291-3297.[Abstract]

Hardan, I., Weiss, L., Hershkoviz, R., Greenspoon, N., Alon, R., Cahalon, L., Reich, S., Slavin, S. and Lider, O (1993). Inhibition of metastatic cell colonization in murine lungs and tumor-induced morbidity by non-peptidic Arg-Gly-Asp mimetics. Int. J. Cancer 55, 1023-1028.[Medline]

Harel, W., Shau, H., Hadley, C. G., Morgan, A. C. Jr, Reisfeld, R. A., Cheresh, D. A. and Mitchell, M. S (1990). Increased lysis of melanoma by in vivo-elicited human lymphokine-activated killer cells after addition of antiganglioside antibodies in vitro. Cancer Res 50, 6311-6315.[Abstract/Free Full Text]

Hart, I. R., Birch, M. and Marshall, J. F (1991). Cell adhesion receptor expression during melanoma progression and metastasis. Cancer Metast. Rev 10, 115-128.[Medline]

Herlyn, D., Herlyn, M., Steplewski, Z. and Koprowski, H (1985). Monoclonal anti-human tumor antibodies of six isotypes in cytotoxic reactions with human and murine effector cells. Cell Immunol 92, 105-114.[Medline]

Herlyn, D., Powe, J., Ross, A. H., Herlyn, M. and Koprowski, H (1985). Inhibition of human tumor growth by IgG2A monoclonal antibodies correlates with antibody density on tumor cells. J. Immunol 134, 1300-1304.[Abstract]

Herlyn, D., Iliopoulos, D., Jensen, P. J., Parmiter, A., Baird, J., Hotta, H., Adachi, K., Ross, A. H., Jambrosic, J., Koprowski, H. et al (1990). In vitro properties of human melanoma cells metastatic in nude mice. Cancer Res 50, 2296-2302.[Abstract/Free Full Text]

Humphries, M. J., Olden, K. and Yamada, K. M (1986). A synthetic peptide from fibronectin inhibits experimental metastasis of murine melanoma cells. Science 233, 467-470.[Abstract/Free Full Text]

Humphries, M. J., Yamada, K. M. and Olden, K (1988). Investigation of the biological effects of anti-cell adhesive synthetic peptides that inhibit experimental metastasis of B16-F10 murine melanoma cells. J. Clin. Invest 81, 782-790.

Hynes, R. O (1992). Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69, 11-25.[Medline]

Kazal, L. A., Ansel, S., Miller, O. P. and Tocantins, L. M (1963). The preparation and some properties of fibrinogen precipitated from human plasma by glycine. Proc. Soc. Exp. Biol. Med 113, 989-994.

Kieffer, N., Fitzgerald, L. A., Wolf, D., Cheresh, D. A. and Phillips, D. R (1991). Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells. J. Cell Biol 113, 451-461.[Abstract/Free Full Text]

Korhonen, M., Ylanne, J., Laitinen, L., Cooper, H. M., Quaranta, V. and Virtanen, I (1991). Distribution of the alpha 1-alpha 6 integrin subunits in human developing and term placenta. Lab. Invest 65, 347-356.[Medline]

Landegren, U (1984). Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens. J. Immunol. Meth 67, 379-388.[Medline]

Lehmann, M., Rabenandrasana, C., Tamura, R., Lissitzky, J., Quaranta, V., Pichon, J. and Marvaldi, J (1994). A monoclonal antibody inhibits adhesion to fibronectin and vitronectin of a colon carcinoma cell line and recognizes the integrins alpha v beta 3, alpha v beta 5, and alpha v beta 6. Cancer Res 54, 2102-2107.[Abstract/Free Full Text]

Lessey, B. A., Damjanovich, L., Coutifaris, C., Castelbaum, A., Albelda, S. M. and Buck, C. A (1992). Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle. J. Clin. Invest 90, 188-195.

Liotta, L. A., Steeg, P. S. and Stetler-Stevenson, W. G (1991). Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64, 327-336.[Medline]

Marshall, J. F., Nesbitt, S. A., Helfrich, M. H., Horton, M. A., Polakova, K. and Hart, I. R (1991). Integrin expression in human melanoma cell lines: heterogeneity of vitronectin receptor composition and function. Int. J. Cancer 49, 924-931.[Medline]

Marshall, J. F., Rutherford, D. C., McCartney, A. C. E., Goodman, S. L., Mitjans, F. C. and Hart, I. R (1995). v 1 is a receptor for vitronectin and fibrinogen, and acts with5 1 to mediate spreading on fibronectin. J. Cell Sci 108, 1227-1238.[Abstract]

Melvaer, K. L. and Fystro, D (1982). Modified micromethod of the Limulus amoebocyte lysate assay for endotoxin. Appl. Environ. Microbiol 43, 493-494.[Abstract/Free Full Text]

Mosmann, T (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Meth 65, 55-63.[Medline]

Moyle, M., Napier, M. A. and McLean, J. W (1991). Cloning and expression of a divergent integrin subunit beta 8. J. Biol. Chem 266, 19650-19658.[Abstract/Free Full Text]

Mujoo, K., Kipps, T. J., Yang, H. M., Cheresh, D. A., Wargalla, U., Sander, D. J. and Reisfeld, R. A (1989). Functional properties and effect on growth suppression of human neuroblastoma tumors by isotype switch variants of monoclonal antiganglioside GD2 antibody 14. 18. Cancer Res 49, 2857-2861.[Abstract/Free Full Text]

Natali, P. G., Nicotra, M. R., Bartolazzi, A., Cavaliere, R. and Bigotti, A (1993). Integrin expression in cutaneous malignant melanoma: association of the alpha 3/beta 1 heterodimer with tumor progression. Int. J. Cancer 54, 68-72.[Medline]

Neff, N. T., Lowrey, C., Decker, C., Tovar, A., Damsky, C., Buck, C. and Horwitz, A. F (1982). A monoclonal antibody detaches embryonic skeletal muscle from extracellular matrices. J. Cell Biol 95, 654-666.[Abstract/Free Full Text]

Nesbitt, S., Nesbit, A., Helfrich, M. and Horton, M (1993). Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins. J. Biol. Chem 268, 16737-16745.[Abstract/Free Full Text]

Orlando, R. A. and Cheresh, D. A (1991). Arginine-glycine-aspartic acid binding leading to molecular stabilization between integrin alpha v beta 3 and its ligand. J. Biol. Chem 266, 19543-19550.[Abstract/Free Full Text]

Panetti, T. S. and McKeown Longo, P. J (1993). Receptor-mediated endocytosis of vitronectin is regulated by its conformational state. J. Biol. Chem 268, 11988-11993.[Abstract/Free Full Text]

Panetti, T. S. and McKeown Longo, P. J (1993). The alpha v beta 5 integrin receptor regulates receptor-mediated endocytosis of vitronectin. J. Biol. Chem 268, 11492-11495.[Abstract/Free Full Text]

Pasqualini, R. and Hemler, M. E (1994). Contrasting roles for integrin beta 1 and beta 5 cytoplasmic domains in subcellular localization, cell proliferation, and cell migration. J. Cell Biol 125, 447-460.[Abstract/Free Full Text]

Paulsson, M., Aumailley, M., Deutzmann, R., Timpl, R., Beck, K. and Engel, J (1987). Laminin-nidogen complex extraction with chelating agents and structural characterization. Eur. J. Biochem 166, 11-19.[Medline]

Pignatelli, M., Cardillo, M. R., Hanby, A. and Stamp, G. W (1992). Integrins and their accessory adhesion molecules in mammary carcinomas: loss of polarization in poorly differentiated tumors. Hum. Pathol 23, 1159-1166.[Medline]

Poste, G., Doll, J., Hart, I. R. and Fidler, I. J (1980). In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res 40, 1636-1644.[Abstract/Free Full Text]

Pytela, R., Pierschbacher, M. D. and Ruoslahti, E (1985). A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin. Proc. Nat. Acad. Sci. USA 82, 5766-5770.[Abstract/Free Full Text]

Pytela, R., Pierschbacher, M. D., Ginsberg, M. H., Plow, E. F. and Ruoslahti, E (1986). Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors. Science 231, 1559-1562.[Abstract/Free Full Text]

Ruoslahti, E., Hayman, E. G., Pierschbacher, M. and Engvall, E (1982). Fibronectin: purification, immunochemical properties, and biological activities. Meth. Enzymol 82, 803-831.

Sanders, L. C., Felding Habermann, B., Mueller, B. M. and Cheresh, D. A (1992). Role of alpha V integrins and vitronectin in human melanoma cell growth. Cold Spring Harb. Symp. Quant. Biol 57, 233-240.[Medline]

Seftor, R. E., Seftor, E. A., Gehlsen, K. R., Stetler Stevenson, W. G., Brown, P. D., Ruoslahti, E. and Hendrix, M. J (1992). Role of the alpha v beta 3 integrin in human melanoma cell invasion. Proc. Nat. Acad. Sci. USA 89, 1557-1561.[Abstract/Free Full Text]

Si, Z. and Hersey, P (1994). Immunohistological examination of therelationship between metastatic potential and expression of adhesion molecules and \324selectins' on melanoma cells. Pathology 26, 6-15.[Medline]

Smith, J. W., Vestal, D. J., Irwin, S. V., Burke, T. A. and Cheresh, D. A (1990). Purification and functional characterization of integrin alpha v beta 5. An adhesion receptor for vitronectin. J. Biol. Chem 265, 11008-11013.[Abstract/Free Full Text]

Smith, J. W. and Cheresh, D. A (1988). The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit. J. Biol. Chem 263, 18726-18731.[Abstract/Free Full Text]

Smith, J. W. and Cheresh, D. A (1990). Integrin (alpha v beta 3)-ligand interaction. Identification of a heterodimeric RGD binding site on the vitronectin receptor. J. Biol. Chem 265, 2168-2172.[Abstract/Free Full Text]

Sonnenberg, A., Modderman, P. W. and Hogervorst, F (1988). Laminin receptor on platelets is the integrin VLA-6. Nature 336, 487-489.[Medline]

Sonnenberg, A (1993). Integrins and their ligands. Curr. Top. Microbiol. Immunol 184, 7-35.[Medline]

Stetler Stevenson, W. G., Aznavoorian, S. and Liotta, L. A (1993). Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell Biol 9, 541-573.

Sutter, A., Hekmat, A. and Luckenbach, G. A (1991). Antibody-mediated tumor cytotoxicity of microglia. Pathobiology 59, 254-258.[Medline]

Takada, Y., Wayner, E. A., Carter, W. G. and Hemler, M. E (1987). Extracellular matrix receptors, ECMRII and ECMRI, for collagen and fibronectin correspond to VLA-2 and VLA-3 in the VLA family of heterodimers. J. Cell. Biochem 37, 385-393.

Tao, M. H. and Morrison, S. L (1989). Studies of aglycosylated chimericmouse-human IgG. Role of carbohydrate in the structure and effector functions mediated by the human IgG constant region. J. Immunol 143, 2595-2601.[Abstract]

Towbin, H., Staehelin, T. and Gordon, J (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets; procedure and some applications. Proc. Nat. Acad. Sci. USA 76, 4350-4354.[Abstract/Free Full Text]

Wayner, E. A., Orlando, R. A. and Cheresh, D. A (1991). Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. J. Cell Biol 113, 919-929.[Abstract/Free Full Text]

Wickham, T. J., Mathias, P., Cheresh, D. A. and Nemerow, G. R (1993). Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 73, 309-319.[Medline]

Yatohgo, T., Izumi, M., Kashiwagi, H. and Hayashi, M (1988). Novel purification of vitronectin from human plasma by heparin affinity chromatography. Cell Struct. Funct 13, 281-292.[Medline]

Yoshinaga, I. G., Vink, J., Dekker, S. K., Mihm, M. C. Jr and Byers, H. R (1993). Role of alpha 3 beta 1 and alpha 2 beta 1 integrins in melanoma cell migration. Melanoma Res 3, 435-441.[Medline]

Zhang, Z., Morla, A. O., Vuori, K., Bauer, J. S., Juliano, R. L. and Ruoslahti, E (1993). The alpha v beta 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin. J. Cell Biol 122, 235-242.[Abstract/Free Full Text]

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				R. Kinsey, M. R. Williamson, S. Chaudhry, K. T. Mellody, A. McGovern, S. Takahashi, C. A. Shuttleworth, and C. M. Kielty Fibrillin-1 microfibril deposition is dependent on fibronectin assembly J. Cell Sci., August 15, 2008; 121(16): 2696 - 2704. [Abstract] [Full Text] [PDF]

				J. M. Roth, M. Caunt, A. Cretu, A. Akalu, D. Policarpio, X. Li, P. Gagne, S. Formenti, and P. C. Brooks Inhibition of Experimental Metastasis by Targeting the HUIV26 Cryptic Epitope in Collagen Am. J. Pathol., May 1, 2006; 168(5): 1576 - 1586. [Abstract] [Full Text] [PDF]

				D. G. McNeel, J. Eickhoff, F. T. Lee, D. M. King, D. Alberti, J. P. Thomas, A. Friedl, J. Kolesar, R. Marnocha, J. Volkman, et al. Phase I Trial of a Monoclonal Antibody Specific for {alpha}v{beta}3 Integrin (MEDI-522) in Patients with Advanced Malignancies, Including an Assessment of Effect on Tumor Perfusion Clin. Cancer Res., November 1, 2005; 11(21): 7851 - 7860. [Abstract] [Full Text] [PDF]

				R. E. Nisato, G. Hosseini, C. Sirrenberg, G. S. Butler, T. Crabbe, A. J.P. Docherty, M. Wiesner, G. Murphy, C. M. Overall, S. L. Goodman, et al. Dissecting the Role of Matrix Metalloproteinases (MMP) and Integrin {alpha}v{beta}3 in Angiogenesis In vitro: Absence of Hemopexin C Domain Bioactivity, but Membrane-Type 1-MMP and {alpha}v{beta}3 Are Critical Cancer Res., October 15, 2005; 65(20): 9377 - 9387. [Abstract] [Full Text] [PDF]

				A. Ebrahimnejad, T. Streichert, P. Nollau, A. K. Horst, C. Wagener, A.-M. Bamberger, and J. Brummer CEACAM1 Enhances Invasion and Migration of Melanocytic and Melanoma Cells Am. J. Pathol., November 1, 2004; 165(5): 1781 - 1787. [Abstract] [Full Text] [PDF]

				M. R. Cominetti, C. H. B. Terruggi, O. H. P. Ramos, J. W. Fox, A. Mariano-Oliveira, M. S. De Freitas, C. C. Figueiredo, V. Morandi, and H. S. Selistre-de-Araujo Alternagin-C, a Disintegrin-like Protein, Induces Vascular Endothelial Cell Growth Factor (VEGF) Expression and Endothelial Cell Proliferation in Vitro J. Biol. Chem., April 30, 2004; 279(18): 18247 - 18255. [Abstract] [Full Text] [PDF]

				N. Imelli, O. Meier, K. Boucke, S. Hemmi, and U. F. Greber Cholesterol Is Required for Endocytosis and Endosomal Escape of Adenovirus Type 2 J. Virol., March 15, 2004; 78(6): 3089 - 3098. [Abstract] [Full Text] [PDF]

				P. A. Burke, S. J. DeNardo, L. A. Miers, K. R. Lamborn, S. Matzku, and G. L. DeNardo Cilengitide Targeting of {alpha}v{beta}3 Integrin Receptor Synergizes with Radioimmunotherapy to Increase Efficacy and Apoptosis in Breast Cancer Xenografts Cancer Res., August 1, 2002; 62(15): 4263 - 4272. [Abstract] [Full Text] [PDF]

				R. A. Sturm, K. Satyamoorthy, F. Meier, B. B. Gardiner, D. J. Smit, B. Vaidya, and M. Herlyn Osteonectin/SPARC Induction by Ectopic {beta}3 Integrin in Human Radial Growth Phase Primary Melanoma Cells Cancer Res., January 1, 2002; 62(1): 226 - 232. [Abstract] [Full Text] [PDF]

				M von Schlippe, J. Marshall, P Perry, M Stone, A. Zhu, and I. Hart Functional interaction between E-cadherin and alphav-containing integrins in carcinoma cells J. Cell Sci., January 2, 2000; 113(3): 425 - 437. [Abstract] [PDF]

				K. Maaser, K. Wolf, C. E. Klein, B. Niggemann, K. S. Zänker, E.-B. Bröcker, and P. Friedl Functional Hierarchy of Simultaneously Expressed Adhesion Receptors: Integrin alpha 2beta 1 but Not CD44 Mediates MV3 Melanoma Cell Migration and Matrix Reorganization within Three-dimensional Hyaluronan-containing Collagen Matrices Mol. Biol. Cell, October 1, 1999; 10(10): 3067 - 3079. [Abstract] [Full Text]

				E. Petitclerc, S. Stromblad, T. L. von Schalscha, F. Mitjans, J. Piulats, A. M. P. Montgomery, D. A. Cheresh, and P. C. Brooks Integrin {{alpha}}V{beta}3 Promotes M21 Melanoma Growth in Human Skin by Regulating Tumor Cell Survival Cancer Res., June 1, 1999; 59(11): 2724 - 2730. [Abstract] [Full Text] [PDF]

				S. Kraft, B. Diefenbach, R. Mehta, A. Jonczyk, G. A. Luckenbach, and S. L. Goodman Definition of an Unexpected Ligand Recognition Motif for alpha vbeta 6 Integrin J. Biol. Chem., January 22, 1999; 274(4): 1979 - 1985. [Abstract] [Full Text] [PDF]

				M.-Y. Hsu, D.-T. Shih, F. E. Meier, P. Van Belle, J.-Y. Hsu, D. E. Elder, C. A. Buck, and M. Herlyn Adenoviral Gene Transfer of �3 Integrin Subunit Induces Conversion from Radial to Vertical Growth Phase in Primary Human Melanoma Am. J. Pathol., November 1, 1998; 153(5): 1435 - 1442. [Abstract] [Full Text] [PDF]

				B. Felding-Habermann, S. Silletti, F. Mei, C.-H. Siu, P. M. Yip, P. C. Brooks, D. A. Cheresh, T. E. O'Toole, M. H. Ginsberg, and A. M.P. Montgomery A Single Immunoglobulin-like Domain of the Human Neural Cell Adhesion Molecule L1 Supports Adhesion by Multiple Vascular and Platelet Integrins J. Cell Biol., December 15, 1997; 139(6): 1567 - 1581. [Abstract] [Full Text] [PDF]