The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Starborg, M.
	Articles by Hoog, C.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Starborg, M.
	Articles by Hoog, C.


Social Bookmarking

	What's this?

Bj\232rklund, S., Skogman, E. and Thelander, L (1992). An S-phase specific release from a transcriptional block regulates the expression of mouse ribonucleotide reductase R2 subunit. EMBO J 11, 4953-4959.[Medline]

Bravo, R. and Macdonald-Bravo, H (1987). Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites. J. Cell Biol 105, 1549-1554.[Abstract/Free Full Text]

Celis, J. E. and Celis, A (1985). Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cell: Subdivision of S phase. Proc. Nat. Acad. Sci. USA 82, 3262-3266.[Abstract/Free Full Text]

Devereux, J., Haeberli, P. and Smithies, O (1984). A comprehensive set of sequence analysis programs for VAX. Nucl. Acids Res 12, 387-395.

Earnshaw, W. C. and Mackay, A. M (1994). Role of nonhistone proteins in the chromosomal events of mitosis. FASEB J 8, 947-956.[Abstract]

Fox, M. H., Arndt-Jovin, D. J., Jovin, T. M., Baumann, P. H. and Robert-Nicoud, M (1991). Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts. J. Cell Sci 99, 247-253.[Abstract/Free Full Text]

Gautier, T., Dauphin-Villemant, C., Andre, C., Masson, C., Arnoult, J. and Hernandez-Verdun, D (1992). Identification and characterization of a new set of nucleolar ribonucleoproteins which line the chromosomes during mitosis. Exp. Cell Res 200, 5-15.[Medline]

Gautier, T., Robert-Nicoud, M., Guilly, M.-N. and Hernandez-Verdun, D (1992). Relocation of nucleolar proteins around chromosomes at mitosis: A study by confocal laser scanning microscopy. J. Cell Sci 102, 729-737.[Abstract/Free Full Text]

Gerdes, J., Schwab, U., Lemke, H. and Stein, H (1983). Production of a monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int. J. Cancer 31, 13-20.[Medline]

Gerdes, J., Lemke, H., Baisch, H., Wacker, H.-H., Schwab, U. and Stein, H (1984). Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J. Immunol 133, 1710-1715.[Abstract]

Gerdes, J (1990). Ki-67 and other proliferation markers useful for immunohistological diagnostic and prognostic evaluations in human malignancies. Semin. Cancer Biol 1, 99-206.[Medline]

Gerdes, J., Li, L., Schlueter, C., Duchrow, M., Wohlenberg, C., Gerlach, C., Stahmer, I., Kloth, S., Brandt, E. and Flad, H.-G (1991). Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am. J. Pathol 138, 867-873.[Abstract]

Hernandez-Verdun, D (1991). The nucleolus today. J. Cell Sci 99, 465-471.[Free Full Text]

H\232\232g, C (1991). Isolation of a large number of novel mammalian genes by a differential cDNA library screening strategy. Nucl. Acids Res 19, 6123-6127.[Abstract/Free Full Text]

Humbert, C., Santisteban, M. S., Usson, Y. and Robert-Nicoud, M (1992). Intranuclear co-localization of newly replicated DNA and PCNA by simultaneous immunofluorescent and confocal microscopy in MCF-7 cells. J. Cell Sci 103, 97-103.[Abstract/Free Full Text]

Isola, J., Helin, H. and Kallioniemi, O.-P (1990). Immunoelectronmicroscopic localization of a proliferation-associated antigen Ki-67 in MCF-7 cells. Histochem. J 22, 498-506.[Medline]

Laemmli, U. K (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.[Medline]

Lopez, F., Belloc, F., Lacombe, F., Dumain, P., Reiffers, J., Bernard, P. and Boisseau, M. R (1994). The labeling of proliferating cells by Ki67 and MIB-1 antibodies depends on the binding of a nuclear protein to the DNA. Exp. Cell Res 210, 145-153.[Medline]

Luji, S., Zumei, N., Shi, Z., Ge, W. and Yang, Y (1987). Involvement of a nucleolar component, perichromonucleolin, in the condensation and decondensation of chromosomes. Proc. Nat. Acad. Sci. USA 84, 7953-7956.[Abstract/Free Full Text]

Nakayasu, H. and Berezney, R (1989). Mapping replication sites in the eucaryote cell nucleus. J. Cell Biol 108, 1-11.[Abstract/Free Full Text]

Ochs, R. L., Lischwe, M. A., Spohn, W. H. and Busch, H (1985). Fibrillarin: a new protein of the nucleolus identified by autoimmune sera. Biol. Cell 54, 123-134.[Medline]

Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. P. and Ehrlich, H. A (1988). Primer directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239, 487-491.[Abstract/Free Full Text]

Sasaki, K., Muramaki, T., Kawasaki, M. and Takahashi, M (1987). The cell cycle associated change of the Ki-67 reactive nuclear antigen expression. J. Cell. Physiol 133, 579-584.[Medline]

Schluter, C., Duchrow, M., Wohlenberg, C., Becker, M. H. G., Key, G., Flad, H.-D. and Gerdes, J (1993). The cell proliferation-associated antigen of antobody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. J. Cell Biol 123, 513-522.[Abstract/Free Full Text]

Schmidt-Zachmann, M. S., Hugle-D\232rr, B. and Franke, W. W (1987). A constitutive nucleolar protein identified as a member of the nucleoplasmin family. EMBO J 6, 1881-1890.[Medline]

Spector, D. L (1993). Macromolecular domains within the cell nucleus. Annu. Rev. Cell Biol 9, 265-315.

Starborg, M., Brundell, E. and H\232\232g, C (1992). Analysis of the expression of a large number of novel genes isolated from mouse prepubertal testis. Mol. Reprod. Dev 33, 243-251.[Medline]

Starborg, M., Brundell, E., Gell, K., Larsson, C., White, I., Daneholt, B. and H\232\232g, C (1995). A murine replication protein accumulates temporarily in the heterochromatic regions of nuclei prior to initiation of DNA replication. J. Cell Sci 108, 927-934.[Abstract]

Suzuki, M (1989). SPXX, a frequent sequence motif in gene regulatory proteins. J. Mol. Biol 207, 61-84.[Medline]

Tyc, K. and Steitz, J. A (1989). U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus. EMBO J 8, 3113-3119.[Medline]

Verheijen, R., Kuijpers, H. J. H., Schlingemann, R. O., Boehmer, A. L. M., van Driel, R., Brakenhoff, G. J. and Ramaekers, F. C. S (1989). Ki-67 detects a nuclear matrix-associated proliferation-related antigen I. Intracellular localization during interphase. J. Cell Sci 92, 123-130.[Abstract/Free Full Text]

Verheijen, R., Kuijpers, H. J. H., van Driel, R., Beck, J. L. M., van Dierendonck, J. H., Brakenhoff, G. J. and Ramaekers, F. C. S (1989). Ki-67 detects a nuclear matrix-associated proliferation-related antigen II. Localization in mitotic cells and association with chromosomes. J. Cell Sci 92, 531-540.[Abstract/Free Full Text]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

S. B.C. Buonomo, Y. Wu, D. Ferguson, and T. de Lange
Mammalian Rif1 contributes to replication stress survival and homology-directed repair
J. Cell Biol., November 2, 2009; 187(3): 385 - 398.
[Abstract] [Full Text] [PDF]

L. Myers, R. J. Messer, A. B. Carmody, and K. J. Hasenkrug
Tissue-Specific Abundance of Regulatory T Cells Correlates with CD8+ T Cell Dysfunction and Chronic Retrovirus Loads
J. Immunol., August 1, 2009; 183(3): 1636 - 1643.
[Abstract] [Full Text] [PDF]

M. A. Shatos, J. Gu, R. R. Hodges, K. Lashkari, and D. A. Dartt
ERK/p44p42 Mitogen-Activated Protein Kinase Mediates EGF-Stimulated Proliferation of Conjunctival Goblet Cells in Culture
Invest. Ophthalmol. Vis. Sci., August 1, 2008; 49(8): 3351 - 3359.
[Abstract] [Full Text] [PDF]

M. K. Sjoberg, E. Shestakova, Z. Mansuroglu, R. B. Maccioni, and E. Bonnefoy
Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization
J. Cell Sci., May 15, 2006; 119(10): 2025 - 2034.
[Abstract] [Full Text] [PDF]

A. Urruticoechea, I. E. Smith, and M. Dowsett
Proliferation Marker Ki-67 in Early Breast Cancer
J. Clin. Oncol., October 1, 2005; 23(28): 7212 - 7220.
[Abstract] [Full Text] [PDF]

A. Dori, J. Cohen, W. F. Silverman, Y. Pollack, and H. Soreq
Functional Manipulations of Acetylcholinesterase Splice Variants Highlight Alternative Splicing Contributions to Murine Neocortical Development
Cereb Cortex, April 1, 2005; 15(4): 419 - 430.
[Abstract] [Full Text] [PDF]

M. Muzi, H. Vesselle, J. R. Grierson, D. A. Mankoff, R. A. Schmidt, L. Peterson, J. M. Wells, and K. A. Krohn
Kinetic Analysis of 3'-Deoxy-3'-Fluorothymidine PET Studies: Validation Studies in Patients with Lung Cancer
J. Nucl. Med., February 1, 2005; 46(2): 274 - 282.
[Abstract] [Full Text] [PDF]

J. Eilbracht, M. Reichenzeller, M. Hergt, M. Schnolzer, H. Heid, M. Stohr, W. W. Franke, and M. S. Schmidt-Zachmann
NO66, a Highly Conserved Dual Location Protein in the Nucleolus and in a Special Type of Synchronously Replicating Chromatin
Mol. Biol. Cell, April 1, 2004; 15(4): 1816 - 1832.
[Abstract] [Full Text] [PDF]

T. Cheutin, M.-F. O'Donohue, A. Beorchia, C. Klein, H. Kaplan, and D. Ploton
Three-dimensional Organization of pKi-67: A Comparative Fluorescence and Electron Tomography Study Using Fluoronanogold
J. Histochem. Cytochem., November 1, 2003; 51(11): 1411 - 1423.
[Abstract] [Full Text] [PDF]

C F Lindboe and S H Torp
Comparison of Ki-67 equivalent antibodies
J. Clin. Pathol., June 1, 2002; 55(6): 467 - 471.
[Abstract] [Full Text] [PDF]

A. Chestukhin, L. Litovchick, K. Rudich, and J. A. DeCaprio
Nucleocytoplasmic Shuttling of p130/RBL2: Novel Regulatory Mechanism
Mol. Cell. Biol., January 15, 2002; 22(2): 453 - 468.
[Abstract] [Full Text] [PDF]

L. J. Wood, M. Mukherjee, C. E. Dolde, Y. Xu, J. F. Maher, T. E. Bunton, J. B. Williams, and L. M. S. Resar
HMG-I/Y, a New c-Myc Target Gene and Potential Oncogene
Mol. Cell. Biol., August 1, 2000; 20(15): 5490 - 5502.
[Abstract] [Full Text]

T. Senoo and N. C. Joyce
Cell Cycle Kinetics in Corneal Endothelium from Old and Young Donors
Invest. Ophthalmol. Vis. Sci., March 1, 2000; 41(3): 660 - 667.
[Abstract] [Full Text]

A. J.H. Suurmeijer and M. E. Boon
Pretreatment in a High-pressure Microwave Processor for MIB-1 Immunostaining of Cytological Smears and Paraffin Tissue Sections to Visualize the Various Phases of the Mitotic Cycle
J. Histochem. Cytochem., August 1, 1999; 47(8): 1015 - 1020.
[Abstract] [Full Text]

M Takagi, Y Matsuoka, T Kurihara, and Y Yoneda
Chmadrin: a novel Ki-67 antigen-related perichromosomal protein possibly implicated in higher order chromatin structure
J. Cell Sci., January 8, 1999; 112(15): 2463 - 2472.
[Abstract] [PDF]

L. Yuan, J. Pelttari, E. Brundell, B. Bjorkroth, J. Zhao, J.-G. Liu, H. Brismar, B. Daneholt, and C. Hoog
The Synaptonemal Complex Protein SCP3 Can Form Multistranded, Cross-striated Fibers In Vivo
J. Cell Biol., July 27, 1998; 142(2): 331 - 339.
[Abstract] [Full Text] [PDF]

N Fomproix, J Gebrane-Younes, and D Hernandez-Verdun
Effects of anti-fibrillarin antibodies on building of functional nucleoli at the end of mitosis
J. Cell Sci., January 2, 1998; 111(3): 359 - 372.
[Abstract] [PDF]

P.-M. Jörgensen, E. Brundell, M. Starborg, and C. Höög
A Subunit of the Anaphase-Promoting Complex Is a Centromere-Associated Protein in Mammalian Cells
Mol. Cell. Biol., January 1, 1998; 18(1): 468 - 476.
[Abstract] [Full Text]

I. Kill
Localisation of the Ki-67 antigen within the nucleolus. Evidence for a fibrillarin-deficient region of the dense fibrillar component
J. Cell Sci., January 6, 1996; 109(6): 1253 - 1263.
[Abstract] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Starborg, M.

Articles by Hoog, C.

Search for Related Content

PubMed

PubMed Citation

Articles by Starborg, M.

Articles by Hoog, C.

Social Bookmarking

What's this?

				L. Myers, R. J. Messer, A. B. Carmody, and K. J. Hasenkrug Tissue-Specific Abundance of Regulatory T Cells Correlates with CD8+ T Cell Dysfunction and Chronic Retrovirus Loads J. Immunol., August 1, 2009; 183(3): 1636 - 1643. [Abstract] [Full Text] [PDF]

				M. A. Shatos, J. Gu, R. R. Hodges, K. Lashkari, and D. A. Dartt ERK/p44p42 Mitogen-Activated Protein Kinase Mediates EGF-Stimulated Proliferation of Conjunctival Goblet Cells in Culture Invest. Ophthalmol. Vis. Sci., August 1, 2008; 49(8): 3351 - 3359. [Abstract] [Full Text] [PDF]

				M. K. Sjoberg, E. Shestakova, Z. Mansuroglu, R. B. Maccioni, and E. Bonnefoy Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization J. Cell Sci., May 15, 2006; 119(10): 2025 - 2034. [Abstract] [Full Text] [PDF]

				A. Urruticoechea, I. E. Smith, and M. Dowsett Proliferation Marker Ki-67 in Early Breast Cancer J. Clin. Oncol., October 1, 2005; 23(28): 7212 - 7220. [Abstract] [Full Text] [PDF]

				A. Dori, J. Cohen, W. F. Silverman, Y. Pollack, and H. Soreq Functional Manipulations of Acetylcholinesterase Splice Variants Highlight Alternative Splicing Contributions to Murine Neocortical Development Cereb Cortex, April 1, 2005; 15(4): 419 - 430. [Abstract] [Full Text] [PDF]

				M. Muzi, H. Vesselle, J. R. Grierson, D. A. Mankoff, R. A. Schmidt, L. Peterson, J. M. Wells, and K. A. Krohn Kinetic Analysis of 3'-Deoxy-3'-Fluorothymidine PET Studies: Validation Studies in Patients with Lung Cancer J. Nucl. Med., February 1, 2005; 46(2): 274 - 282. [Abstract] [Full Text] [PDF]

				J. Eilbracht, M. Reichenzeller, M. Hergt, M. Schnolzer, H. Heid, M. Stohr, W. W. Franke, and M. S. Schmidt-Zachmann NO66, a Highly Conserved Dual Location Protein in the Nucleolus and in a Special Type of Synchronously Replicating Chromatin Mol. Biol. Cell, April 1, 2004; 15(4): 1816 - 1832. [Abstract] [Full Text] [PDF]

				T. Cheutin, M.-F. O'Donohue, A. Beorchia, C. Klein, H. Kaplan, and D. Ploton Three-dimensional Organization of pKi-67: A Comparative Fluorescence and Electron Tomography Study Using Fluoronanogold J. Histochem. Cytochem., November 1, 2003; 51(11): 1411 - 1423. [Abstract] [Full Text] [PDF]

				C F Lindboe and S H Torp Comparison of Ki-67 equivalent antibodies J. Clin. Pathol., June 1, 2002; 55(6): 467 - 471. [Abstract] [Full Text] [PDF]

				A. Chestukhin, L. Litovchick, K. Rudich, and J. A. DeCaprio Nucleocytoplasmic Shuttling of p130/RBL2: Novel Regulatory Mechanism Mol. Cell. Biol., January 15, 2002; 22(2): 453 - 468. [Abstract] [Full Text] [PDF]

				L. J. Wood, M. Mukherjee, C. E. Dolde, Y. Xu, J. F. Maher, T. E. Bunton, J. B. Williams, and L. M. S. Resar HMG-I/Y, a New c-Myc Target Gene and Potential Oncogene Mol. Cell. Biol., August 1, 2000; 20(15): 5490 - 5502. [Abstract] [Full Text]

				T. Senoo and N. C. Joyce Cell Cycle Kinetics in Corneal Endothelium from Old and Young Donors Invest. Ophthalmol. Vis. Sci., March 1, 2000; 41(3): 660 - 667. [Abstract] [Full Text]

				A. J.H. Suurmeijer and M. E. Boon Pretreatment in a High-pressure Microwave Processor for MIB-1 Immunostaining of Cytological Smears and Paraffin Tissue Sections to Visualize the Various Phases of the Mitotic Cycle J. Histochem. Cytochem., August 1, 1999; 47(8): 1015 - 1020. [Abstract] [Full Text]

				M Takagi, Y Matsuoka, T Kurihara, and Y Yoneda Chmadrin: a novel Ki-67 antigen-related perichromosomal protein possibly implicated in higher order chromatin structure J. Cell Sci., January 8, 1999; 112(15): 2463 - 2472. [Abstract] [PDF]

				L. Yuan, J. Pelttari, E. Brundell, B. Bjorkroth, J. Zhao, J.-G. Liu, H. Brismar, B. Daneholt, and C. Hoog The Synaptonemal Complex Protein SCP3 Can Form Multistranded, Cross-striated Fibers In Vivo J. Cell Biol., July 27, 1998; 142(2): 331 - 339. [Abstract] [Full Text] [PDF]

				N Fomproix, J Gebrane-Younes, and D Hernandez-Verdun Effects of anti-fibrillarin antibodies on building of functional nucleoli at the end of mitosis J. Cell Sci., January 2, 1998; 111(3): 359 - 372. [Abstract] [PDF]

				P.-M. Jörgensen, E. Brundell, M. Starborg, and C. Höög A Subunit of the Anaphase-Promoting Complex Is a Centromere-Associated Protein in Mammalian Cells Mol. Cell. Biol., January 1, 1998; 18(1): 468 - 476. [Abstract] [Full Text]

				I. Kill Localisation of the Ki-67 antigen within the nucleolus. Evidence for a fibrillarin-deficient region of the dense fibrillar component J. Cell Sci., January 6, 1996; 109(6): 1253 - 1263. [Abstract] [PDF]