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Bandara, L. R. and La Thangue, N. B (1991). Adenovirus Ela prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature 351, 494-497.[Medline]

Bandara, L. R., Adamczewski, J. P., Hunt, T. and La Thangue, N. B (1991). Cyclin A and the retinoblastoma gene product complex with a common transcription factor. Nature 352, 249-251.[Medline]

Bandara, L. R., Buck, V. M., Zamanian, M., Johnston, L. H. and La Thangue, N. B (1993). Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J 13, 4317-4324.

Bandara, L. R., Lam, E. W.-F., Sorensen, T. S., Zamanian, M., Girling, R. and La Thangue, N. B (1994). DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein. EMBO J 13, 3104-3114.[Medline]

Beijersbergen, R. L., Kerkhoven, R. M., Zhu, L., Carlee, L., Voorhoeve, P. M. and Bernards, R (1994). E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev 8, 2680-2690.[Abstract/Free Full Text]

Beijersbergen, R. L., Carlee, L., Kerkhoven, R. M. and Bernards, R (1995). Regulation of the retinoblastoma protein-related p107 by G1cyclin complexes. Genes Dev 9, 1340-1353.[Abstract/Free Full Text]

Bentolila, L. A., d'Andon, M. F. Nguyen, Q. T., Martinez, O., Rougeon, F. and Doyen, N (1995). The two isoforms of mouse terminal deoxynucleotidyl transferase differ in both the ability to add N regions and subcellular localization. EMBO J 14, 4221-4229.[Medline]

Boulikas, T (1993). Nuclear localization signals (NLS). Crit. Rev. Euk. Gene Exp 3, 193-227.[Medline]

Boulikas, T (1994). Putative nuclear localization signals (NLS) in protein transcription factors. J. Cell. Biochem 55, 32-38.[Medline]

Buck, V., Allen, K. E., Sorensen, T., Bybee, A., Hijmans, E. M., Voorhoeve, P. M., Bernards, R. and La Thangue, N. B (1995). Molecular and functional characterisation of E2F-5, a new member of the E2F family. Oncogene 11, 31-38.[Medline]

Chang, J., Lee K. J., Jang, K. L., Lee, E. K., Baek, G. H. and Sung, Y. C (1995). Human foamy virus Bel1 transactivator contains a bipartite nuclear localization determinant which is sensitive to protein context and triple multimerization domains. J. Virol 69, 801-808.[Abstract]

Chellappan, S. P., Hiebert, S., Mudryj, M., Horowitz, J. M. and Nevins, J. R (1991). The E2F transcription factor is a cellular target for the Rb protein. Cell 65, 1053-1061.[Medline]

Chellappan, S., Kraus, V. B., Kroger, Bu., Munger, K., Howley, M., Phelps, W. C. and Nevins, J. R (1992). Adenovirus E1A, simian virua 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc. Nat. Acad. Sci. USA 89, 4549-4553.[Abstract/Free Full Text]

Dingwall, C. and Laskey, R (1991). Nuclear targeting sequences- a common consensus?. Trends Biochem. Sci 16, 478-481.[Medline]

Dowdy, S. F., Hinds, P. W., Louie, K., Reed, S. I., Arnold, A. and Weinberg, R. A (1993). Physical interaction of the retinoblastoma protein with human cyclins. Cell 73, 499-511.[Medline]

Evans, R. M (1988). The steroid and thyroid hormone receptor superfamily. Science 240, 889-895.[Abstract/Free Full Text]

Ewen, M. E., Sluss, H. K., Sherr, C. J., Matsushime, H., Kato, J. Y. and Livingston, D. M (1993). Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell 73, 487-497.[Medline]

Fabre, E. and Hurt, E. C (1994). Nuclear transport. Curr. Opin. Cell Biol 6, 335-342.[Medline]

Flemington, E. K., Speck, S. H. and Kaelin, W. G (1993). Mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product. Proc. Nat. Acad. Sci. USA 90, 6914-6918.[Abstract/Free Full Text]

Ginsberg, D., Vairo, G., Chittendon, T., Xiao, Z.-X., Xu, G., Wydner, K. K., De Caprio, J. A., Lawrence, J. B. and Livingston, D. M (1994). E2F-4, a new E2F transcription factor family member, interacts with p107 and has transforming potential. Genes Dev 8, 2939-2952.[Abstract/Free Full Text]

Girling, R., Partridge, J. F., Bandara, L. R., Burden, N., Totty, N. F., Hsuan, J. J. and La Thangue, N. B (1993). A new component of the transcription factor DRTF1/E2F. Nature 362, 83-87.[Medline]

Girling, R., Bandara, L. R., Ormondroyd, E., Lam, E. W.-F., Kotecha, S., Mohun, T. and La Thangue, N. B (1994). Molecular characterisation of Xenopus laevis DP proteins. Mol. Biol. Cell 5, 1081-1092.[Abstract]

Helin, K., Lees, J. A., Vidal, M., Dyson, N., Harlow, E. and Fattaey, A (1992). A cDNA encoding a pRb-binding protein with properties of the transcription factor E2F. Cell 70, 337-350.[Medline]

Helin, K., Harlow, E. and Fattaey, A. R (1993). Inhibition of E2F-1 trans-activation by direct binding of the retinoblastoma protein. Mol. Cell. Biol 13, 6501-6508.[Abstract/Free Full Text]

Helin, K., Wu, C.-L., Fattaey, A. R., Lees, J. A., Dynlacht, B. D., Ngwu, C. and Harlow, E (1993). Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev 7, 1850-1861.[Abstract/Free Full Text]

Hiebert, S. W., Chellappan, S. P., Horowitz, J. M. and Nevins, J. R (1992). The interaction of Rb with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev 6, 177-185.[Abstract/Free Full Text]

Hijmans, E. M., Voorhoeve, P. M., Beijersbergen, R. L., Veer, L. J. van't and Bernards, R (1995). E2F-5, a new E2F family member that interacts with p130 i n vivo . Mol. Cell. Biol 15, 3082-3089.

Hinds, P. W., Mittnacht, S., Dulic, V., Arnold, A., Reed, S. I. and Weinberg, R. A (1992). Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 70, 993-1006.[Medline]

Ivey-Hoyle, M., Conroy, R., Huber, H. E., Goodhart, P. J., Oliff, A. and Heimbrook, D. C (1993). Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol. Cell. Biol 13, 7802-7812.

Johnson, D. G., Cress, W. D., Jakoi, L. and Nevins, J. R (1994). Oncogenic capacity of the E2F-1 gene. Proc. Nat. Acad. Sci. USA 91, 12823-12827.[Abstract/Free Full Text]

Jooss, K., Lam, E. W.-F., Bybee, A., Girling, R., Muller, R. and La Thangue, N. B (1995). Proto-oncogenic properties of the DP family of proteins. Oncogene 10, 1529-1536.[Medline]

Kaelin, W. G., Krek, W., Sellers, W. R., De Caprio, J. A., Ajchanbaum, F., Fuchs, C. S., Chittenden, T., Li. Y., Farnham, P. J., Blanar, M. A., Livingston, D. M. and Flemington, E. K (1992). Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell 70, 351-364.[Medline]

Krek, W., Livingston, D. M. and Shirodkar, S (1993). Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science 262, 1557-1560.[Abstract/Free Full Text]

Krek, W., Ewen, M. E., Shirodkar, S., Arany, Z., Kaelin, W. G. and Livingston, D. M (1994). Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 78, 161-172.[Medline]

Krek, W., Xu, G. and Livingston, D. M (1995). Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell 83, 1149-1158.[Medline]

La Casse, E. C. and Lefebvre, Y. A (1995). Nuclear localization signals overlap DNA-or RNA binding domains in nucleic acid binding proteins. Nucl. Acids Res 23, 1647-1656.[Free Full Text]

La Thangue, N. B (1994). DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control. Trends Biochem. Sci 19, 108-114.[Medline]

Lees, E., Faha, B., Dulic, V., Reed, S. I. and Harlow, E (1992). Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct matter. Genes Dev 6, 1874-1885.[Abstract/Free Full Text]

Lees, J. A., Saito, M., Vidal, M., Valentine, M., Look, T., Harlow, E., Dyson, N. and Helin, K (1993). The retinoblastoma protein binds to a family of E2F transcription factors. Mol. Cell. Biol 13, 7813-7825.[Abstract/Free Full Text]

Makela, T. P., Koskinen, P. J., Vastrik, L. and Alitalo, K (1992). Alternative forms of Max as enhancers or suppressors of Myc-ras co-transformation. Science 256, 373-377.[Abstract/Free Full Text]

Martin, K., Trouche, D., Hagemeier, C., S\277rensen, T. S., La Thangue, N. B. and Kouzarides, T (1995). Stimulation of E2F/DP1 transcriptional activity by MDM2 oncoprotein. Nature 375, 691-694.[Medline]

Melchior, F. and Gerace, L (1995). Mechanisms of nuclear protein import. Curr. Opin. Cell Biol 7, 310-318.[Medline]

Mittnacht, S. and Weinberg, R. A (1991). G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment. Cell 65, 381-393.[Medline]

Morris, J. D., Crook, T., Bandara, L. R., Davies, R., La Thangue, N. B. and Vousden, K. H (1993). Human papillomavirus type 16 E7 regulates E2F and contributes to mitogenic signalling. Oncogene 8, 893-898.[Medline]

Muller, R (1995). Transcriptional regulation during the mammalian cell cycle. Trends Genet 11, 173-178.[Medline]

Nevins, J. R (1992). E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 258, 424-429.[Abstract/Free Full Text]

Ormondroyd, E., de la Luna, S. and La Thangue, N. B (1995). A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F. Oncogene 11, 1437-1446.[Medline]

Robbins, J., Dilworth, S. M., Laskey, R. A. and Dingwall, C (1991). Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 64, 615-623.[Medline]

Sardet, C., Vidal, M., Cobrinik, D., Geng, Y., Onufryk, C., Chen, A. and Weinberg, R. A (1995). E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc. Nat. Acad. Sci. USA 92, 2403-2407.[Abstract/Free Full Text]

Schwarz, J. K., Devoto, S. H., Smith, E. J., Chellappan, S. P., Jakoi, L. and Nevins, J. R (1993). Interactions of the p107 and Rb proteins with E2F during the cell proliferation response. EMBO J 12, 1013-1020.[Medline]

Shan, B., Zhu, X., Chen, P.-L., Durfee, T., Yang, Y., Sharp, D. and Lee, W. H (1992). Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: Identification of a gene with properties of the transcription factor E2F. Mol. CellBiol 12, 5620-5631.[Abstract/Free Full Text]

Sherr, C. J (1993). Mammalian G1 cyclins. Cell 73, 1059-1065.[Medline]

Slansky, J. E., Li, Y., Kaelin, W. G. and Farnham, P. J (1993). A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter. Mol. Cell Biol 13, 1610-1618.[Abstract/Free Full Text]

Srinivasan, M., Edman, C. F. and Schulman, H (1994). Alternative splicingintroduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus. J. CellBiol 126, 839-852.[Abstract/Free Full Text]

Tang, T. K., Tang, C. C., Chao, Y. J. and Wu, C (1994). Nuclear mitotic apparatus protein (NuMA): spindle association, nuclear targeting and differential subcellular localization of various NuMA isoforms. J. Cell Sci 107, 1389-1402.[Abstract]

Vairo, G., Livingston, D. M. and Ginsberg, D (1995). Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. Genes Dev 9, 869-881.[Abstract/Free Full Text]

Vandromme, M., Gauthierrouviere, C., Lamb, N. and Fernandez, A (1996). Regulation of transcription factor localization- fine tuning of gene-expression. Trends Biochem. Sci 21, 59-64.[Medline]

Webster, N. J. G., Green, S., Tasset, D., Ponglikitmongkol, M. and Chambon, P (1989). The transcriptional activation function located in the hormone binding domain of the human estrogen receptor is not encoded in a single exon. EMBO. J 8, 1441-1446.[Medline]

Weinberg, R. A (1995). The retinoblastoma protein and cell cycle control. Cell 81, 323-330.[Medline]

Whiteside, S. T. and Goodbourn, S (1993). Signal transduction and nuclear targeting: regulation of transcription factor activity by subcellular localisation. J. Cell Sci 104, 949-955.[Medline]

Wolf, D. A., Hermeking, H., Albert, T., Herzinger, T., Kind, P. and Eick, D (1995). A complex between E2F and the pRb-related protein p130 is specifically targeted by the simian virus 40 large T antigen during cell transformation. Oncogene 10, 2067-2078.[Medline]

Wu, C. L., Zukerberg, L. R., Ngwu, C., Harlow, E. and Lees J. A (1995). In vivo association of E2F and DP family proteins. Mol. Cell Biol 15, 2536-2546.[Abstract]

Zamanian, M. and La Thangue, N. B (1992). Adenovirus E1A prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor. EMBO J 11, 2603-2610.[Medline]

Zamanian, M. and La Thangue, N. B (1993). Transcriptional repression by the Rb-related protein p107. Mol. Biol. Cell 4, 389-396.[Abstract]

Zhang, Y. and Chellappan, S. P (1995). Cloning and characterisation of human DP-2, a novel dimerization partner of E2F. Oncogene 10, 2085-2093.[Medline]

Zhu, L., Van den Heuvel, S., Helin, K., Fattaey, A., Ewen, M., Livingston, D., Dyson, N. and Harlow, E (1993). Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes Dev 7, 1111-1125.[Abstract/Free Full Text]

Zhu, L., Enders, G., Lees, J. A., Beijersbergen, R. L., Bernards, R. and Harlow, E (1995). The pRb-related protein p107 contains two growth suppression domains: independent interactions with E2F and cyclin/cdk complexes. EMBO J 14, 1904-1913.[Medline]

Zhu, L., Harlow, E. and Dynlacht, B. D (1995). p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F. Genes Dev 9, 1740-1752.[Abstract/Free Full Text]




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