Regulation of the CYP1A1 promoter in transgenic mice: an exquisitely sensitive on-off system for cell specific gene regulation

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				R. M. Ortiz, M. L. Graciano, J. J. Mullins, and K. D. Mitchell Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats Am J Physiol Renal Physiol, November 1, 2007; 293(5): F1584 - F1591. [Abstract] [Full Text] [PDF]

				R. D. Finn, A. W. McLaren, D. Carrie, C. J. Henderson, and C. R. Wolf Conditional Deletion of Cytochrome P450 Oxidoreductase in the Liver and Gastrointestinal Tract: A New Model for Studying the Functions of the P450 System J. Pharmacol. Exp. Ther., July 1, 2007; 322(1): 40 - 47. [Abstract] [Full Text] [PDF]

				M. L. Graciano, C. R. Mouton, M. E. Patterson, D. M. Seth, J. J. Mullins, and K. D. Mitchell Renal vascular and tubulointerstitial inflammation and proliferation in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension Am J Physiol Renal Physiol, June 1, 2007; 292(6): F1858 - F1866. [Abstract] [Full Text] [PDF]

				T. N. Operana, N. Nguyen, S. Chen, D. Beaton, and R. H. Tukey Human CYP1A1GFP Expression in Transgenic Mice Serves as a Biomarker for Environmental Toxicant Exposure Toxicol. Sci., January 1, 2007; 95(1): 98 - 107. [Abstract] [Full Text] [PDF]

				A. L. Opay, C. R. Mouton, J. J. Mullins, and K. D. Mitchell Cyclooxygenase-2 inhibition normalizes arterial blood pressure in CYP1A1-REN2 transgenic rats with inducible ANG II-dependent malignant hypertension Am J Physiol Renal Physiol, September 1, 2006; 291(3): F612 - F618. [Abstract] [Full Text] [PDF]

				K. D Mitchell, S. J Bagatell, C. S Miller, C. R Mouton, D. M Seth, and J. J Mullins Genetic Clamping of Renin Gene Expression Induces Hypertension and Elevation of Intrarenal Ang II Levels of Graded Severity in Cyp1a1-Ren2 Transgenic Rats Journal of Renin-Angiotensin-Aldosterone System, June 1, 2006; 7(2): 74 - 86. [Abstract] [PDF]

				K. D. Mitchell and J. J. Mullins Enhanced tubuloglomerular feedback in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension Am J Physiol Renal Physiol, December 1, 2005; 289(6): F1210 - F1216. [Abstract] [Full Text] [PDF]

				M. E. Patterson, C. R. Mouton, J. J. Mullins, and K. D. Mitchell Interactive effects of superoxide anion and nitric oxide on blood pressure and renal hemodynamics in transgenic rats with inducible malignant hypertension Am J Physiol Renal Physiol, October 1, 2005; 289(4): F754 - F759. [Abstract] [Full Text] [PDF]

				L. L. Howard, M. E. Patterson, J. J. Mullins, and K. D. Mitchell Salt-sensitive hypertension develops after transient induction of ANG II-dependent hypertension in Cyp1a1-Ren2 transgenic rats Am J Physiol Renal Physiol, April 1, 2005; 288(4): F810 - F815. [Abstract] [Full Text] [PDF]

				S. J. Campbell, C. J. Henderson, D. C. Anthony, D. Davidson, A. J. Clark, and C. R. Wolf The Murine Cyp1a1 Gene Is Expressed in a Restricted Spatial and Temporal Pattern during Embryonic Development J. Biol. Chem., February 18, 2005; 280(7): 5828 - 5835. [Abstract] [Full Text] [PDF]

				A. Galijatovic, D. Beaton, N. Nguyen, S. Chen, J. Bonzo, R. Johnson, S. Maeda, M. Karin, F. P. Guengerich, and R. H. Tukey The Human CYP1A1 Gene Is Regulated in a Developmental and Tissue-specific Fashion in Transgenic Mice J. Biol. Chem., June 4, 2004; 279(23): 23969 - 23976. [Abstract] [Full Text] [PDF]

				C. J. Henderson and C. R. Wolf Transgenic Analysis of Human Drug-Metabolizing Enzymes: Preclinical Drug Development and Toxicology Mol. Interv., September 1, 2003; 3(6): 331 - 343. [Abstract] [Full Text] [PDF]

				E. Bockamp, M. Maringer, C. Spangenberg, S. Fees, S. Fraser, L. Eshkind, F. Oesch, and B. Zabel Of mice and models: improved animal models for biomedical research Physiol Genomics, December 3, 2002; 11(3): 115 - 132. [Abstract] [Full Text] [PDF]

				K. Gradin, R. Toftgard, L. Poellinger, and A. Berghard Repression of Dioxin Signal Transduction in Fibroblasts. IDENTIFICATION OF A PUTATIVE REPRESSOR ASSOCIATED WITH Arnt J. Biol. Chem., May 7, 1999; 274(19): 13511 - 13518. [Abstract] [Full Text] [PDF]