Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site

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				B. T. Goult, N. Bate, N. J. Anthis, K. L. Wegener, A. R. Gingras, B. Patel, I. L. Barsukov, I. D. Campbell, G. C. K. Roberts, and D. R. Critchley The Structure of an Interdomain Complex That Regulates Talin Activity J. Biol. Chem., May 29, 2009; 284(22): 15097 - 15106. [Abstract] [Full Text] [PDF]

				M. Himmel, A. Ritter, S. Rothemund, B. V. Pauling, K. Rottner, A. R. Gingras, and W. H. Ziegler Control of High Affinity Interactions in the Talin C Terminus: HOW TALIN DOMAINS COORDINATE PROTEIN DYNAMICS IN CELL ADHESIONS J. Biol. Chem., May 15, 2009; 284(20): 13832 - 13842. [Abstract] [Full Text] [PDF]

				A. R. Gingras, W. H. Ziegler, A. A. Bobkov, M. G. Joyce, D. Fasci, M. Himmel, S. Rothemund, A. Ritter, J. G. Grossmann, B. Patel, et al. Structural Determinants of Integrin Binding to the Talin Rod J. Biol. Chem., March 27, 2009; 284(13): 8866 - 8876. [Abstract] [Full Text] [PDF]

				K. R. Legate and R. Fassler Mechanisms that regulate adaptor binding to {beta}-integrin cytoplasmic tails J. Cell Sci., January 15, 2009; 122(2): 187 - 198. [Abstract] [Full Text] [PDF]

				M. Vicente-Manzanares, C. K. Choi, and A. R. Horwitz Integrins in cell migration - the actin connection J. Cell Sci., January 15, 2009; 122(2): 199 - 206. [Abstract] [Full Text] [PDF]

				E. M. Mace, S. J. Monkley, D. R. Critchley, and F. Takei A Dual Role for Talin in NK Cell Cytotoxicity: Activation of LFA-1-Mediated Cell Adhesion and Polarization of NK Cells J. Immunol., January 15, 2009; 182(2): 948 - 956. [Abstract] [Full Text] [PDF]

				J. Srivastava, G. Barreiro, S. Groscurth, A. R. Gingras, B. T. Goult, D. R. Critchley, M. J. S. Kelly, M. P. Jacobson, and D. L. Barber Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling PNAS, September 23, 2008; 105(38): 14436 - 14441. [Abstract] [Full Text] [PDF]

				C. Le Clainche and M.-F. Carlier Regulation of Actin Assembly Associated With Protrusion and Adhesion in Cell Migration Physiol Rev, April 1, 2008; 88(2): 489 - 513. [Abstract] [Full Text] [PDF]

				J. D. Humphries, P. Wang, C. Streuli, B. Geiger, M. J. Humphries, and C. Ballestrem Vinculin controls focal adhesion formation by direct interactions with talin and actin J. Cell Biol., December 3, 2007; 179(5): 1043 - 1057. [Abstract] [Full Text] [PDF]

				M. Moes, S. Rodius, S. J. Coleman, S. J. Monkley, E. Goormaghtigh, L. Tremuth, C. Kox, P. P. G. van der Holst, D. R. Critchley, and N. Kieffer The Integrin Binding Site 2 (IBS2) in the Talin Rod Domain Is Essential for Linking Integrin beta Subunits to the Cytoskeleton J. Biol. Chem., June 8, 2007; 282(23): 17280 - 17288. [Abstract] [Full Text] [PDF]

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