Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase

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				J. M. Carter, L. Demizieux, R. B. Campenot, D. E. Vance, and J. E. Vance Phosphatidylcholine Biosynthesis via CTP:Phosphocholine Cytidylyltransferase 2 Facilitates Neurite Outgrowth and Branching J. Biol. Chem., January 4, 2008; 283(1): 202 - 212. [Abstract] [Full Text] [PDF]

				C. L. Bevan, D. M. Porter, C. R. Schumann, E. Y. Bryleva, T. J. Hendershot, H. Liu, M. J. Howard, and L. P. Henderson The Endocrine-Disrupting Compound, Nonylphenol, Inhibits Neurotrophin-Dependent Neurite Outgrowth Endocrinology, September 1, 2006; 147(9): 4192 - 4204. [Abstract] [Full Text] [PDF]

				H. Yang and R. R. Mattingly The Ras-GRF1 Exchange Factor Coordinates Activation of H-Ras and Rac1 to Control Neuronal Morphology Mol. Biol. Cell, May 1, 2006; 17(5): 2177 - 2189. [Abstract] [Full Text] [PDF]

				L. M. Ooms, C. G. Fedele, M. V. Astle, I. Ivetac, V. Cheung, R. B. Pearson, M. J. Layton, A. Forrai, H. H. Nandurkar, and C. A. Mitchell The Inositol Polyphosphate 5-Phosphatase, PIPP, Is a Novel Regulator of Phosphoinositide 3-Kinase-dependent Neurite Elongation Mol. Biol. Cell, February 1, 2006; 17(2): 607 - 622. [Abstract] [Full Text] [PDF]

				K. Chakrabarti, R. Lin, N. I. Schiller, Y. Wang, D. Koubi, Y.-X. Fan, B. B. Rudkin, G. R. Johnson, and M. R. Schiller Critical Role for Kalirin in Nerve Growth Factor Signaling through TrkA Mol. Cell. Biol., June 15, 2005; 25(12): 5106 - 5118. [Abstract] [Full Text] [PDF]

				X.-M. Chen, P. L. Splinter, P. S. Tietz, B. Q. Huang, D. D. Billadeau, and N. F. LaRusso Phosphatidylinositol 3-Kinase and Frabin Mediate Cryptosporidium parvum Cellular Invasion via Activation of Cdc42 J. Biol. Chem., July 23, 2004; 279(30): 31671 - 31678. [Abstract] [Full Text] [PDF]

				S. Musatov, J. Roberts, A. I. Brooks, J. Pena, S. Betchen, D. W. Pfaff, and M. G. Kaplitt Inhibition of neuronal phenotype by PTEN in PC12 cells PNAS, March 9, 2004; 101(10): 3627 - 3631. [Abstract] [Full Text] [PDF]

				K. Aoki, T. Nakamura, and M. Matsuda Spatio-temporal Regulation of Rac1 and Cdc42 Activity during Nerve Growth Factor-induced Neurite Outgrowth in PC12 Cells J. Biol. Chem., January 2, 2004; 279(1): 713 - 719. [Abstract] [Full Text] [PDF]

				J. Mills, M. Digicaylioglu, A. T. Legg, C. E. Young, S. S. Young, A. M. Barr, L. Fletcher, T. P. O'Connor, and S. Dedhar Role of Integrin-Linked Kinase in Nerve Growth Factor-Stimulated Neurite Outgrowth J. Neurosci., March 1, 2003; 23(5): 1638 - 1648. [Abstract] [Full Text] [PDF]

				S. Elowe, S. J. Holland, S. Kulkarni, and T. Pawson Downregulation of the Ras-Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction Mol. Cell. Biol., November 1, 2001; 21(21): 7429 - 7441. [Abstract] [Full Text] [PDF]

				M. Rosário, H. F. Paterson, and C. J. Marshall Activation of the Ral and Phosphatidylinositol 3' Kinase Signaling Pathways by the Ras-Related Protein TC21 Mol. Cell. Biol., June 1, 2001; 21(11): 3750 - 3762. [Abstract] [Full Text]

				O. Bang, E. Park, S. Yang, S. Lee, T. Franke, and S. Kang Overexpression of Akt inhibits NGF-induced growth arrest and neuronal differentiation of PC12 cells J. Cell Sci., January 1, 2001; 114(1): 81 - 88. [Abstract] [PDF]

				R. D. York, D. C. Molliver, S. S. Grewal, P. E. Stenberg, E. W. McCleskey, and P. J. S. Stork Role of Phosphoinositide 3-Kinase and Endocytosis in Nerve Growth Factor-Induced Extracellular Signal-Regulated Kinase Activation via Ras and Rap1 Mol. Cell. Biol., November 1, 2000; 20(21): 8069 - 8083. [Abstract] [Full Text]

				M. W. Wooten, M. L. Seibenhener, K. B. W. Neidigh, and M. L. Vandenplas Mapping of Atypical Protein Kinase C within the Nerve Growth Factor Signaling Cascade: Relationship to Differentiation and Survival of PC12 Cells Mol. Cell. Biol., July 1, 2000; 20(13): 4494 - 4504. [Abstract] [Full Text]

				T. Laux, K. Fukami, M. Thelen, T. Golub, D. Frey, and P. Caroni Gap43, Marcks, and Cap23 Modulate Pi(4,5)p2 at Plasmalemmal Rafts, and Regulate Cell Cortex Actin Dynamics through a Common Mechanism J. Cell Biol., June 26, 2000; 149(7): 1455 - 1472. [Abstract] [Full Text] [PDF]

				S. Sarner, R. Kozma, S. Ahmed, and L. Lim Phosphatidylinositol 3-Kinase, Cdc42, and Rac1 Act Downstream of Ras in Integrin-Dependent Neurite Outgrowth in N1E-115 Neuroblastoma Cells Mol. Cell. Biol., January 1, 2000; 20(1): 158 - 172. [Abstract] [Full Text]

				T. Sakai, T. Furuyama, Y. Ohoka, N. Miyazaki, S.-h. Fujioka, H. Sugimoto, M. Amasaki, S. Hattori, T. Matsuya, and S. Inagaki Mouse Semaphorin H Induces PC12 Cell Neurite Outgrowth Activating Ras-Mitogen-activated Protein Kinase Signaling Pathway via Ca2+ Influx J. Biol. Chem., October 15, 1999; 274(42): 29666 - 29671. [Abstract] [Full Text] [PDF]

				J. G. Pastorino, M. Tafani, and J. L. Farber Tumor Necrosis Factor Induces Phosphorylation and Translocation of BAD through a Phosphatidylinositide-3-OH Kinase-dependent Pathway J. Biol. Chem., July 2, 1999; 274(27): 19411 - 19416. [Abstract] [Full Text] [PDF]

				T. Goi, G. Rusanescu, T. Urano, and L. A. Feig Ral-Specific Guanine Nucleotide Exchange Factor Activity Opposes Other Ras Effectors in PC12 Cells by Inhibiting Neurite Outgrowth Mol. Cell. Biol., March 1, 1999; 19(3): 1731 - 1741. [Abstract] [Full Text] [PDF]

				K Venkateswarlu, F Gunn-Moore, J. Tavare, and P. Cullen EGF-and NGF-stimulated translocation of cytohesin-1 to the plasma membrane of PC12 cells requires PI 3-kinase activation and a functional cytohesin-1 PH domain J. Cell Sci., January 6, 1999; 112(12): 1957 - 1965. [Abstract] [PDF]

				L. J. Klesse and L. F. Parada p21 Ras and Phosphatidylinositol-3 Kinase Are Required for Survival of Wild-Type and NF1 Mutant Sensory Neurons J. Neurosci., December 15, 1998; 18(24): 10420 - 10428. [Abstract] [Full Text] [PDF]

				B. Kim, P. S. Leventhal, M. F. White, and E. L. Feldman Differential Regulation of Insulin Receptor Substrate-2 and Mitogen-Activated Protein Kinase Tyrosine Phosphorylation by Phosphatidylinositol 3-Kinase Inhibitors in SH-SY5Y Human Neuroblastoma Cells Endocrinology, December 1, 1998; 139(12): 4881 - 4889. [Abstract] [Full Text] [PDF]

				G. Gallo and P. C. Letourneau Localized Sources of Neurotrophins Initiate Axon Collateral Sprouting J. Neurosci., July 15, 1998; 18(14): 5403 - 5414. [Abstract] [Full Text] [PDF]

				D. Plenz and S. T. Kitai Regulation of the Nigrostriatal Pathway by Metabotropic Glutamate Receptors during Development J. Neurosci., June 1, 1998; 18(11): 4133 - 4144. [Abstract] [Full Text] [PDF]

				Y Kita, K. Kimura, M Kobayashi, S Ihara, K Kaibuchi, S Kuroda, M Ui, H Iba, H Konishi, U Kikkawa, et al. Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway J. Cell Sci., January 4, 1998; 111(7): 907 - 915. [Abstract] [PDF]

				K. L. Philpott, M. J. McCarthy, A. Klippel, and L. L. Rubin Activated Phosphatidylinositol 3-Kinase and Akt Kinase Promote Survival of Superior Cervical Neurons J. Cell Biol., November 3, 1997; 139(3): 809 - 815. [Abstract] [Full Text] [PDF]

				R. Busca, C. Bertolotto, J.-P. Ortonne, and R. Ballotti Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation J. Biol. Chem., December 13, 1996; 271(50): 31824 - 31830. [Abstract] [Full Text] [PDF]

				LatanyaP. Hammonds-Odie, TrevorR. Jackson, AdamA. Profit, IraJ. Blader, ChristophW. Turck, GlennD. Prestwich, and AnneB. Theibert Identification and Cloning of Centaurin-alpha . A NOVEL PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-BINDING PROTEIN FROM RAT BRAIN J. Biol. Chem., August 2, 1996; 271(31): 18859 - 18868. [Abstract] [Full Text] [PDF]

				H. Sawai, D. B. Clarke, P. Kittlerova, G. M. Bray, and A. J. Aguayo Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Stimulate Growth of Axonal Branches from Regenerating Retinal Ganglion Cells J. Neurosci., June 15, 1996; 16(12): 3887 - 3894. [Abstract] [Full Text] [PDF]

				H. Yasui, H. Katoh, Y. Yamaguchi, J. Aoki, H. Fujita, K. Mori, and M. Negishi Differential Responses to Nerve Growth Factor and Epidermal Growth Factor in Neurite Outgrowth of PC12 Cells Are Determined by Rac1 Activation Systems J. Biol. Chem., April 27, 2001; 276(18): 15298 - 15305. [Abstract] [Full Text] [PDF]