MT-MMP, the cell surface activator of proMMP-2 (pro-gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis

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Brown, P. D., Levy, A. T., Margulies, I. M. K., Liotta, L. A. and Stetler-Stevenson, W. G (1990). Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res 50, 6184-6191.[Abstract/Free Full Text]

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				A. Ota, H. Yonemoto, A. Someya, S. Itoh, K. Kinoshita, and I. Nagaoka Changes in Matrix Metalloproteinase 2 Activities in Amniochorions During Premature Rupture of Membranes Reproductive Sciences, December 1, 2006; 13(8): 592 - 597. [Abstract] [PDF]

				S X Bai, Y L Wang, L Qin, Z J Xiao, R Herva, and Y S Piao Dynamic expression of matrix metalloproteinases (MMP-2, -9 and -14) and the tissue inhibitors of MMPs (TIMP-1, -2 and -3) at the implantation site during tubal pregnancy Reproduction, January 1, 2005; 129(1): 103 - 113. [Abstract] [Full Text] [PDF]

				K. Mori, M. Shibanuma, and K. Nose Invasive Potential Induced under Long-Term Oxidative Stress in Mammary Epithelial Cells Cancer Res., October 15, 2004; 64(20): 7464 - 7472. [Abstract] [Full Text] [PDF]

				S. Yun, A. Dardik, M. Haga, A. Yamashita, S. Yamaguchi, Y. Koh, J. A. Madri, and B. E. Sumpio Transcription Factor Sp1 Phosphorylation Induced by Shear Stress Inhibits Membrane Type 1-Matrix Metalloproteinase Expression in Endothelium J. Biol. Chem., September 13, 2002; 277(38): 34808 - 34814. [Abstract] [Full Text] [PDF]

				K. Lehti, J. Lohi, M. M. Juntunen, D. Pei, and J. Keski-Oja Oligomerization through Hemopexin and Cytoplasmic Domains Regulates the Activity and Turnover of Membrane-type 1 Matrix Metalloproteinase J. Biol. Chem., March 1, 2002; 277(10): 8440 - 8448. [Abstract] [Full Text] [PDF]

				H. Hayashita-Kinoh, H. Kinoh, A. Okada, K. Komori, Y. Itoh, T. Chiba, M. Kajita, I. Yana, and M. Seiki Membrane-Type 5 Matrix Metalloproteinase Is Expressed in Differentiated Neurons and Regulates Axonal Growth Cell Growth Differ., November 1, 2001; 12(11): 573 - 580. [Abstract] [Full Text] [PDF]

				S.-T. Khuth, H. Akaoka, A. Pagenstecher, O. Verlaeten, M.-F. Belin, P. Giraudon, and A. Bernard Morbillivirus Infection of the Mouse Central Nervous System Induces Region-Specific Upregulation of MMPs and TIMPs Correlated to Inflammatory Cytokine Expression J. Virol., September 1, 2001; 75(17): 8268 - 8282. [Abstract] [Full Text] [PDF]

				H. Wang, Q. Li, L. Shao, and C. Zhu Expression of Matrix Metalloproteinase-2, -9, -14, and Tissue Inhibitors of Metalloproteinase-1, -2, -3 in the Endometrium and Placenta of Rhesus Monkey (Macaca mulatta) During Early Pregnancy Biol Reprod, July 1, 2001; 65(1): 31 - 40. [Abstract] [Full Text] [PDF]

				H.-Y. Ha, H.-B. Moon, M.-S. Nam, J.-W. Lee, Z.-Y. Ryoo, T.-H. Lee, K.-K. Lee, B.-J. So, H. Sato, M. Seiki, et al. Overexpression of Membrane-type Matrix Metalloproteinase-1 Gene Induces Mammary Gland Abnormalities and Adenocarcinoma in Transgenic Mice Cancer Res., February 1, 2001; 61(3): 984 - 990. [Abstract] [Full Text]

				Y. Fukuda, M. Ishizaki, Y. Okada, M. Seiki, and N. Yamanaka Matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in fetal rabbit lung Am J Physiol Lung Cell Mol Physiol, September 1, 2000; 279(3): L555 - L561. [Abstract] [Full Text] [PDF]

				Y. Kubota, T. Ninomiya, S. Oka, Y. Takenoshita, and K. Shirasuna Interleukin-1{alpha}-dependent Regulation of Matrix Metalloproteinase-9 (MMP-9) Secretion and Activation in the Epithelial Cells of Odontogenic Jaw Cysts Journal of Dental Research, June 1, 2000; 79(6): 1423 - 1430. [Abstract] [PDF]

				A. R. Nelson, B. Fingleton, M. L. Rothenberg, and L. M. Matrisian Matrix Metalloproteinases: Biologic Activity and Clinical Implications J. Clin. Oncol., March 1, 2000; 18(5): 1135 - 1135. [Abstract] [Full Text] [PDF]

				T. Sato, T. Kondo, T. Fujisawa, M. Seiki, and A. Ito Furin-independent Pathway of Membrane Type 1-Matrix Metalloproteinase Activation in Rabbit Dermal Fibroblasts J. Biol. Chem., December 24, 1999; 274(52): 37280 - 37284. [Abstract] [Full Text] [PDF]

				J. E. Park, M. C. Lenter, R. N. Zimmermann, P. Garin-Chesa, L. J. Old, and W. J. Rettig Fibroblast Activation Protein, a Dual Specificity Serine Protease Expressed in Reactive Human Tumor Stromal Fibroblasts J. Biol. Chem., December 17, 1999; 274(51): 36505 - 36512. [Abstract] [Full Text] [PDF]

				Y. S. Kanwar, K. Ota, Q. Yang, J. Wada, N. Kashihara, Y. Tian, and E. I. Wallner Role of membrane-type matrix metalloproteinase 1 (MT-1-MMP), MMP-2, and its inhibitor in nephrogenesis Am J Physiol Renal Physiol, December 1, 1999; 277(6): F934 - F947. [Abstract] [Full Text] [PDF]

				J. Esparza, C. Vilardell, J. Calvo, M. Juan, J. Vives, A. Urbano-Marquez, J. Yague, and M. C. Cid Fibronectin Upregulates Gelatinase B (MMP-9) and Induces Coordinated Expression of Gelatinase A (MMP-2) and Its Activator MT1-MMP (MMP-14) by Human T Lymphocyte Cell Lines. A Process Repressed Through RAS/MAP Kinase Signaling Pathways Blood, October 15, 1999; 94(8): 2754 - 2766. [Abstract] [Full Text] [PDF]

				J. Cao, M. Drews, H. M. Lee, C. Conner, W. F. Bahou, and S. Zucker The Propeptide Domain of Membrane Type 1�Matrix Metalloproteinase Is Required for Binding of Tissue Inhibitor of Metalloproteinases and for Activation of Pro-gelatinase A J. Biol. Chem., December 25, 1998; 273(52): 34745 - 34752. [Abstract] [Full Text] [PDF]

				N. Theret, O. Musso, A. L'Helgoualc'h, J.-P. Campion, and B. Clement Differential Expression and Origin of Membrane-Type 1 and 2 Matrix Metalloproteinases (MT-MMPs) in Association with MMP2 Activation in Injured Human Livers Am. J. Pathol., September 1, 1998; 153(3): 945 - 954. [Abstract] [Full Text] [PDF]

				K. Kusano, C. Miyaura, M. Inada, T. Tamura, A. Ito, H. Nagase, K. Kamoi, and T. Suda Regulation of Matrix Metalloproteinases (MMP-2, -3, -9, and -13) by Interleukin-1 and Interleukin-6 in Mouse Calvaria: Association of MMP Induction with Bone Resorption Endocrinology, March 1, 1998; 139(3): 1338 - 1345. [Abstract] [Full Text] [PDF]

				S. Zucker, M. Drews, C. Conner, H. D. Foda, Y. A. DeClerck, K. E. Langley, W. F. Bahou, A. J.�P. Docherty, and J. Cao Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Binds to the Catalytic Domain of the Cell Surface Receptor, Membrane Type 1-Matrix Metalloproteinase 1�(MT1-MMP) J. Biol. Chem., January 9, 1998; 273(2): 1216 - 1222. [Abstract] [Full Text] [PDF]

				S. S. Apte, N. Fukai, D. R. Beier, and B. R. Olsen The Matrix Metalloproteinase-14 (MMP-14) Gene Is Structurally Distinct from Other MMP Genes and Is Co-expressed with the TIMP-2 Gene during Mouse Embryogenesis J. Biol. Chem., October 10, 1997; 272(41): 25511 - 25517. [Abstract] [Full Text] [PDF]

				A. Okada, C. Tomasetto, Y. Lutz, J.-P. Bellocq, M.-C. Rio, and P. Basset Expression of Matrix Metalloproteinases during Rat Skin Wound Healing: Evidence that Membrane Type-1 Matrix Metalloproteinase Is a Stromal Activator of Pro-Gelatinase A J. Cell Biol., April 7, 1997; 137(1): 67 - 77. [Abstract] [Full Text] [PDF]

				T Sato, M del Carmen Ovejero, P Hou, A. Heegaard, M Kumegawa, N. Foged, and J. Delaisse Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts J. Cell Sci., January 3, 1997; 110(5): 589 - 596. [Abstract] [PDF]

				N. Fukui, A. McAlinden, Y. Zhu, E. Crouch, T. J. Broekelmann, R. P. Mecham, and L. J. Sandell Processing of Type II Procollagen Amino Propeptide by Matrix Metalloproteinases J. Biol. Chem., January 11, 2002; 277(3): 2193 - 2201. [Abstract] [Full Text] [PDF]

				S. Silletti, T. Kessler, J. Goldberg, D. L. Boger, and D. A. Cheresh Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo PNAS, January 2, 2001; 98(1): 119 - 124. [Abstract] [Full Text] [PDF]

				Z. Zhou, S. S. Apte, R. Soininen, R. Cao, G. Y. Baaklini, R. W. Rauser, J. Wang, Y. Cao, and K. Tryggvason Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I PNAS, April 11, 2000; 97(8): 4052 - 4057. [Abstract] [Full Text] [PDF]

				T. Uekita, Y. Itoh, I. Yana, H. Ohno, and M. Seiki Cytoplasmic tail-dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity J. Cell Biol., December 24, 2001; 155(7): 1345 - 1356. [Abstract] [Full Text] [PDF]