The subcellular distribution of the high molecular mass protein, HD1, is determined by the cytoplasmic domain of the integrin beta 4 subunit

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				K. Raymond, M. Kreft, H. Janssen, J. Calafat, and A. Sonnenberg Keratinocytes display normal proliferation, survival and differentiation in conditional {beta}4-integrin knockout mice J. Cell Sci., March 1, 2005; 118(5): 1045 - 1060. [Abstract] [Full Text] [PDF]

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				L. Fontao, D. Geerts, I. Kuikman, J. Koster, D. Kramer, and A. Sonnenberg The interaction of plectin with actin: evidence for cross-linking of actin filaments by dimerization of the actin-binding domain of plectin J. Cell Sci., January 6, 2001; 114(11): 2065 - 2076. [Abstract] [Full Text] [PDF]

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				M. Nievers, I Kuikman, D Geerts, I. Leigh, and A Sonnenberg Formation of hemidesmosome-like structures in the absence of ligand binding by the (alpha)6(beta)4 integrin requires binding of HD1/plectin to the cytoplasmic domain of the (beta)4 integrin subunit J. Cell Sci., January 3, 2000; 113(6): 963 - 973. [Abstract] [PDF]

				S. B. Hopkinson and J. C. R. Jones The N Terminus of the Transmembrane Protein BP180 Interacts with the N-terminal Domain of BP230, Thereby Mediating Keratin Cytoskeleton Anchorage to the Cell Surface at the Site of the Hemidesmosome Mol. Biol. Cell, January 1, 2000; 11(1): 277 - 286. [Abstract] [Full Text]

				D. Geerts, L. Fontao, M. G. Nievers, R. Q.J. Schaapveld, P. E. Purkis, G. N. Wheeler, E. B. Lane, I. M. Leigh, and A. Sonnenberg Binding of Integrin {alpha}6{beta}4 to Plectin Prevents Plectin Association with F-Actin but Does Not Interfere with Intermediate Filament Binding J. Cell Biol., October 18, 1999; 147(2): 417 - 434. [Abstract] [Full Text] [PDF]

				I. Rabinovitz, A. Toker, and A. M. Mercurio Protein Kinase C�dependent Mobilization of the {alpha}6{beta}4 Integrin from Hemidesmosomes and Its Association with Actin-rich Cell Protrusions Drive the Chemotactic Migration of Carcinoma Cells J. Cell Biol., September 6, 1999; 146(5): 1147 - 1160. [Abstract] [Full Text] [PDF]

				D. Ramarli, M. T. Scupoli, E. Fiorini, O. Poffe, M. Brentegani, A. Villa, G. Cecchini, G. Tridente, and P. C. Marchisio Thymocyte Contact or Monoclonal Antibody-Mediated Clustering of alpha 3beta 1 or alpha 6beta 4 Integrins Activate Interleukin-6 (IL-6) Transcription Factors (NF-kappa B and NF-IL6) and IL-6 Production in Human Thymic Epithelial Cells Blood, November 15, 1998; 92(10): 3745 - 3755. [Abstract] [Full Text] [PDF]

				R. Q.J. Schaapveld, L. Borradori, D. Geerts, M. R. van Leusden, I. Kuikman, M. G. Nievers, C. M. Niessen, R. D.M. Steenbergen, P. J.F. Snijders, and A. Sonnenberg Hemidesmosome Formation Is Initiated by the beta 4 Integrin Subunit, Requires Complex Formation of beta 4 and HD1/Plectin, and Involves a Direct Interaction between beta 4 and the Bullous Pemphigoid Antigen 180� J. Cell Biol., July 13, 1998; 142(1): 271 - 284. [Abstract] [Full Text] [PDF]

				G. A. Rezniczek, J. M. de Pereda, S. Reipert, and G. Wiche Linking Integrin alpha 6beta 4-based Cell Adhesion to the Intermediate Filament Cytoskeleton: Direct Interaction between the beta 4 Subunit and Plectin at Multiple Molecular Sites J. Cell Biol., April 6, 1998; 141(1): 209 - 225. [Abstract] [Full Text] [PDF]

				S. Homan, A. Mercurio, and S. LaFlamme Endothelial cells assemble two distinct alpha6beta4-containing vimentin-associated structures: roles for ligand binding and the beta4 cytoplasmic tail J. Cell Sci., January 9, 1998; 111(18): 2717 - 2728. [Abstract] [PDF]

				M. Nievers, R. Schaapveld, L. Oomen, L Fontao, D Geerts, and A Sonnenberg Ligand-independent role of the beta 4 integrin subunit in the formation of hemidesmosomes J. Cell Sci., January 6, 1998; 111(12): 1659 - 1672. [Abstract] [PDF]

				I. Rabinovitz and A. M. Mercurio The Integrin alpha 6beta 4 Functions in Carcinoma Cell Migration on Laminin-1 by Mediating the Formation and Stabilization of Actin-containing Motility Structures J. Cell Biol., December 29, 1997; 139(7): 1873 - 1884. [Abstract] [Full Text] [PDF]

				L. Borradori, P. J. Koch, C. M. Niessen, S. Erkeland, M. R.�v. Leusden, and A. Sonnenberg The Localization of Bullous Pemphigoid Antigen 180�(BP180) in Hemidesmosomes Is Mediated by Its Cytoplasmic Domain and Seems to be Regulated by the beta 4 Integrin Subunit J. Cell Biol., March 24, 1997; 136(6): 1333 - 1347. [Abstract] [Full Text] [PDF]

				C. Niessen, E. Hulsman, L. Oomen, I Kuikman, and A Sonnenberg A minimal region on the integrin beta4 subunit that is critical to its localization in hemidesmosomes regulates the distribution of HD1/plectin in COS-7 cells J. Cell Sci., January 8, 1997; 110(15): 1705 - 1716. [Abstract] [PDF]