A mutation in a highly conserved region in brush-border sucrase-isomaltase and lysosomal alpha-glucosidase results in Golgi retention

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				M. Keiser, M. Alfalah, M. J. Propsting, D. Castelletti, and H. Y. Naim Altered Folding, Turnover, and Polarized Sorting Act in Concert to Define a Novel Pathomechanism of Congenital Sucrase-Isomaltase Deficiency J. Biol. Chem., May 19, 2006; 281(20): 14393 - 14399. [Abstract] [Full Text] [PDF]

				D. Castelletti, G. Fracasso, M. Alfalah, S. Cingarlini, M. Colombatti, and H. Y. Naim Apical Transport and Folding of Prostate-specific Membrane Antigen Occurs Independent of Glycan Processing J. Biol. Chem., February 10, 2006; 281(6): 3505 - 3512. [Abstract] [Full Text] [PDF]

				M. J. Propsting, H. Kanapin, R. Jacob, and H. Y. Naim A phenylalanine-based folding determinant in intestinal sucrase-isomaltase that functions in the context of a quality control mechanism beyond the endoplasmic reticulum J. Cell Sci., June 15, 2005; 118(12): 2775 - 2784. [Abstract] [Full Text] [PDF]

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				M. Nauze, L. Gonin, B. Chaminade, C. Peres, F. Hullin-Matsuda, B. Perret, H. Chap, and A. Gassama-Diagne Guinea Pig Phospholipase B, Identification of the Catalytic Serine and the Proregion Involved in Its Processing and Enzymatic Activity J. Biol. Chem., November 8, 2002; 277(46): 44093 - 44099. [Abstract] [Full Text] [PDF]

				C. M. Haynes, S. Caldwell, and A. A. Cooper An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport J. Cell Biol., July 8, 2002; 158(1): 91 - 102. [Abstract] [Full Text] [PDF]

				M. Alfalah, R. Jacob, and H. Y. Naim Intestinal Dipeptidyl Peptidase IV Is Efficiently Sorted to the Apical Membrane through the Concerted Action of N- and O-Glycans as Well as Association with Lipid Microdomains J. Biol. Chem., March 15, 2002; 277(12): 10683 - 10690. [Abstract] [Full Text] [PDF]

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				M. A.B. Axelsson, N. G. Karlsson, D. M. Steel, J. Ouwendijk, T. Nilsson, and G. C. Hansson Neutralization of pH in the Golgi apparatus causes redistribution of glycosyltransferases and changes in the O-glycosylation of mucins Glycobiology, August 1, 2001; 11(8): 633 - 644. [Abstract] [Full Text] [PDF]

				R. Jacob, M. Alfalah, J. Grunberg, M. Obendorf, and H. Y. Naim Structural Determinants Required for Apical Sorting of an Intestinal Brush-border Membrane Protein J. Biol. Chem., February 25, 2000; 275(9): 6566 - 6572. [Abstract] [Full Text] [PDF]

				M. Garbutt, L. M. J. Law, H. Chan, and T. C. Hobman Role of Rubella Virus Glycoprotein Domains in Assembly of Virus-Like Particles J. Virol., May 1, 1999; 73(5): 3524 - 3533. [Abstract] [Full Text]

				R. Jacob, U. Preuss, P. Panzer, M. Alfalah, S. Quack, M. G. Roth, H. Naim, and H. Y. Naim Hierarchy of Sorting Signals in Chimeras of Intestinal Lactase-Phlorizin Hydrolase and the Influenza Virus Hemagglutinin J. Biol. Chem., March 19, 1999; 274(12): 8061 - 8067. [Abstract] [Full Text] [PDF]

				N. Spodsberg, R. Jacob, M. Alfalah, K.-P. Zimmer, and H. Y. Naim Molecular Basis of Aberrant Apical Protein Transport in an Intestinal Enzyme Disorder J. Biol. Chem., June 22, 2001; 276(26): 23506 - 23510. [Abstract] [Full Text] [PDF]