Intracellular acidification induces apoptosis by stimulating ICE-like protease activity

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				X. Lu, W. Qin, J. Li, N. Tan, D. Pan, H. Zhang, L. Xie, G. Yao, H. Shu, M. Yao, et al. The Growth and Metastasis of Human Hepatocellular Carcinoma Xenografts Are Inhibited by Small Interfering RNA Targeting to the Subunit ATP6L of Proton Pump Cancer Res., August 1, 2005; 65(15): 6843 - 6849. [Abstract] [Full Text] [PDF]

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				C. Terminella, K. Tollefson, J. Kroczynski, J. Pelli, and M. Cutaia Inhibition of apoptosis in pulmonary endothelial cells by altered pH, mitochondrial function, and ATP supply Am J Physiol Lung Cell Mol Physiol, December 1, 2002; 283(6): L1291 - L1302. [Abstract] [Full Text] [PDF]

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				D. Liu, G. Martino, M. Thangaraju, M. Sharma, F. Halwani, S.-H. Shen, Y. C. Patel, and C. B. Srikant Caspase-8-mediated Intracellular Acidification Precedes Mitochondrial Dysfunction in Somatostatin-induced Apoptosis J. Biol. Chem., March 24, 2000; 275(13): 9244 - 9250. [Abstract] [Full Text] [PDF]

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				A. R. Khaled, K. Kim, R. Hofmeister, K. Muegge, and S. K. Durum From the Cover: Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH PNAS, December 7, 1999; 96(25): 14476 - 14481. [Abstract] [Full Text] [PDF]

				M. Thangaraju, K. Sharma, B. Leber, D. W. Andrews, S.-H. Shen, and C. B. Srikant Regulation of Acidification and Apoptosis by SHP-1 and Bcl-2 J. Biol. Chem., October 8, 1999; 274(41): 29549 - 29557. [Abstract] [Full Text] [PDF]

				M. L. Anthony, M. Zhao, and K. M. Brindle Inhibition of Phosphatidylcholine Biosynthesis following Induction of Apoptosis in HL-60 Cells J. Biol. Chem., July 9, 1999; 274(28): 19686 - 19692. [Abstract] [Full Text] [PDF]

				R. Benson, C Dive, and A. Watson Cytoplasmic acidification is not an effector mechanism of VP16 or DEX-induced apoptosis in CEM T leukaemia cells J. Cell Sci., January 6, 1999; 112(11): 1755 - 1760. [Abstract] [PDF]

				J. G. Pryde, A. Walker, A. G. Rossi, S. Hannah, and C. Haslett Temperature-dependent Arrest of Neutrophil Apoptosis. FAILURE OF Bax INSERTION INTO MITOCHONDRIA AT 15 {degrees}C PREVENTS THE RELEASE OF CYTOCHROME c J. Biol. Chem., October 20, 2000; 275(43): 33574 - 33584. [Abstract] [Full Text] [PDF]

				J. L. Hirpara, M.-V. Clement, and S. Pervaiz Intracellular Acidification Triggered by Mitochondrial-derived Hydrogen Peroxide Is an Effector Mechanism for Drug-induced Apoptosis in Tumor Cells J. Biol. Chem., January 5, 2001; 276(1): 514 - 521. [Abstract] [Full Text] [PDF]

				R. Marches, E. S. Vitetta, and J. W. Uhr A role for intracellular pH in membrane IgM-mediated cell death of human B lymphomas PNAS, March 13, 2001; 98(6): 3434 - 3439. [Abstract] [Full Text] [PDF]

				S. Roy, C. I. Bayly, Y. Gareau, V. M. Houtzager, S. Kargman, S. L. C. Keen, K. Rowland, I. M. Seiden, N. A. Thornberry, and D. W. Nicholson Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide PNAS, May 22, 2001; 98(11): 6132 - 6137. [Abstract] [Full Text] [PDF]