Acid modulation of HT29 cell growth and differentiation. An in vitro model for Barrett's esophagus

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Fitzgerald, R. C.
	Articles by Triadafilopoulos, G.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Fitzgerald, R. C.
	Articles by Triadafilopoulos, G.


Social Bookmarking

	What's this?

Barnard, J. A. and Warwick, G (1993). Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. Cell Growth Differ 4, 495-501.[Abstract]

Beauregard, M. C. D., Pringault, E., Robine, S. and Louvard, D (1995). Suppression of villin expression by antisense RNA on brush border assembly in polarized epithelial intestinal cells. EMBO J 14, 409-421.[Medline]

Boller, K., Arpin, M., Pringault, E. and Reggio, H (1988). Differential distribution of villin and villin mRNA in mouse intestinal epithelial cells. Differentiation 39, 51-57.[Medline]

Bretscher, A. and Weber, K (1980). Villin is a major protein of microvillus cytoskeleton which binds G and F actin in a calcium-dependent manner. Cell 20, 839-.[Medline]

Bretscher, A., Osborn, A., Wehland, J. and Weber, K (1981). Villin associates with specific microfilamentous structures as seen by immunofluorescence microscopy on tissue sections and cells microinjected with villin. Exp. Cell Res 135, 213-219.[Medline]

Cutz, E., Rhoads, J. M., Drumm, B., Shermann, P. M., Drurie, P. and Forstner, G. G (1989). Microvillus inclusion disease: an inherited defect of brush-border assembly and differentiation. New Eng. J. Med 320, 646-651.[Medline]

Fath, K. R. and Burgess, D. R (1995). Not actin alone. Curr. Biol 5, 591-593.[Medline]

Fischer, H (1989). Malignancy may contribute to rapid evolution. Med. Hypoth 28, 35-38.[Medline]

Fitzgerald, R. C., Omary, M. B. and Triadafilopoulos, G (1996). Dynamic effects of acid on Barrett's esophagus: an ex vivo differentiation and proliferation model. J. Clin. Invest 98, 2-.

Friederich, E., Huet, C., Arpin, M. and Louvard, D (1989). Villin induces microvilli growth and actin redistribution in transfected fibroblasts. Cell 59, 461-475.[Medline]

Friederich, E., Vancompernolle, K., Huet, C., Goethals, M., Finidon, J., Vandejerckhove, J. and Louvard, D (1992). An actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin. Cell 70, 81-92.[Medline]

Gerson, D. F., Keifer, H. and Eufe, W (1982). Intacellular pH of mitogen stimulated lymphocytes. Science 216, 1009-1010.[Abstract/Free Full Text]

Grinstein, S. and Rothstein, A (1986). Mechanisms of regulation of the Na+/H+exchanger. J. Membr. Biol 90, 1-12.[Medline]

Grinstein, S., Riotin, D. and Mason, M. J (1989). Na/H exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation. Biochim. Biophys. Acta 988, 73-97.[Medline]

Heerdt, B. G., Houston, M. A. and Augenlicht, L. A (1994). Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res 54, 3288-3294.[Abstract/Free Full Text]

Hertz, F., Schermer, A., Hawler, M. and Bogart, L. H (1981). Alkaline phosphatase in HT-29, a human cancer cell line: influence of sodium butyrate and hyperosmolality. Arch. Biochem. Biophys 210, 581-591.[Medline]

Hoffman, E. K. and Simonsen, L. O (1989). Membrane mechanisms in volume and pH regulation in vertebrate cells. Physiol. Rev 69, 315-378.[Free Full Text]

Isfort, R. J., Cody, D. B., Asquith, T. N., Ridder, G. M., Stuard, S. B. and LeBoeuf, R. A (1993). Induction of protein phosphorylation, protein synthesis, immediate early gene expression and cellular proliferation by intracellular pH modulation. Eur. J. Biochem 231, 349-357.

Kraus, M., Severin, T. and Wolf, B (1994). Relevance of microenvironmental pH for self-organized tumor growth and invasion. Anticancer Res 14, 1573-1583.[Medline]

Kumble, S., Omary, M. B., Fajardo, L. F. and Triadafilopoulos, G (1996). Multifocal heterogeneity in villin and Ep-cam expression in Barrett's esophagus. Int. J. Cancer 66, 48-54.[Medline]

Laemmli, U. K (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.[Medline]

Levine, D. S., Rubin, C. E., Reid, B. J. and Haggitt, R (1989). Specialized metaplstic columnar epithelium in Barrett's esophagus: a comparative transmission electron microscopic study. Lab. Invest 60, 418-432.[Medline]

Lupton, J. R. and Kurtz, P. P (1993). Relationship of colonic luminal short-chain fatty acids and pH to in vivo cell proliferation in rats. J. Nutr 123, 1522-1530.

Madshus, I. H (1988). Regulation of intracellular pH in eukaryotic cells. Biochem. J 250, 1-8.[Medline]

Martin, G. and Jain, R (1994). Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy. Cancer Res 54, 5670-5674.[Abstract/Free Full Text]

Matsudaira, P. T. and Burgess, D. R (1979). Identification and organization of the compartments of the isolated microvillus cytoskeleton. J. Cell Biol 83, 667-673.[Abstract/Free Full Text]

McDougall, C. J., Wong, R., Scudera, P., Lesser, M. and Cosse, J. J. D (1993). Colonic mucosal pH in humans. Dig. Dis. Sci 38, 542-545.[Medline]

Moolenar, W. H (1986). Effects of growth factors on intracellular pH regulation. Annu. Rev. Physiol 48, 363-376.[Medline]

Moolenar, W. H., Defize, L. H. K. and DeLaat, S. W (1986). Ionic signaling by growth factor receptors. J. Exp. Biol 124, 359-373.[Abstract/Free Full Text]

Mooseker, M. S (1985). Organization, chemistry and assembly of the cytoskeletal apparatus of the intestinal brush border. Annu. Rev. Cell Biol 1, 209-241.

Ober, S. S. and Pardee, A. B (1987). Intracellular pH is increased after transformation of chinese hamster embryo fibroblasts. Proc. Nat. Acad. Sci. USA 84, 2766-2770.[Abstract/Free Full Text]

Pardee, A. B (1989). G1events and regulation of cell proliferation. Science 246, 603-608.[Abstract/Free Full Text]

Pinto, M., Appay, M. D., Simon-Assmann, P., Chevalier, G., Dracopoli, N., Fogh, J. and Zweibaum, A (1982). Enterocytic differentiation of culturedhuman colon cancer cells by replacement of glucose by galactose in the medium. Biol. Cell 44, 193-196.

Pringault, E. M., Arpin, M., Garcia, A., Findori, A. and Louvard, D. A (1986). Human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo. EMBO J 5, 3119-3124.[Medline]

Reid, B. J (1991). Barrett's esophagus and esophageal adenocarcinoma. Gastroenterol. Clin. North Amer 20, 817-834.[Medline]

Rhoads, J. M., Cogler, R. C., Lacey, S. R., Reddick, R. L., Keku, E. O., Azizkhan, R. G. and Berschneider, H. M (1991). Microvillus inclusion disease: in vitro electrolyte transport. Gastroenterology 100, 811-817.[Medline]

Robine, S. C., Huet, R., Moll, R., C Sahuquillo-Merino, Coudrier, E., Zweibaum, A. and Louvard, D (1985). Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells?. Proc. Nat. Acad. Sci 8, 8488-8492.

Rotin, D., Steele-Nirwood, D., Grinstein, S. and Tannock, I (1989). Requirement of the Na/H exchanger for tumor growth. Cancer Res 49, 205-211.[Abstract/Free Full Text]

Shackney, S. and Shankey, T (1995). Genetic and phenotypic heterogeneity of human malignancies: finding order in chaos. Cytometry 21, 2-5.[Medline]

Shibayama, T., Carboni, J. M. and Mooseker, M. S (1987). Assembly of the intestinal brush border: appearance and redistribution of microvillar core proteins in developing chick enterocytes. J. Cell Biol 105, 335-344.[Abstract/Free Full Text]

Soleimani, M., Bizal, G., mcKinney, T. and Hattabaugh, Y (1992). Effect of in vitro metabolic acidosis on luminal Na+/H+exchange, and basolateral Na+:HCO3cotransport in rabbit kidney proximal tubules. J. Clin. Invest 90, 211-218.

Soleimani, M., Hattabaugh, Y. and Bizal, G (1994). Effects of in vitro acid-base disorders on Na+/H+exchange, Cl-/base exchange, and Na+:HCO3cotransport in rabbit kidney proximal tubules. J. Lab. Clin. Med 124, 69-78.[Medline]

Stidwill, R. P., Wysolmerski, T. and Burgess, D. R (1984). The brush border cytoskeleton is not static: In vivo turnover of proteins. J. Cell Biol 98, 641-645.[Abstract/Free Full Text]

Tobey, N. A., Srighar, P. R., Keku, T. O., Jr, E. J. C. and Orlando, R. C (1993). Mechanisms of HCl-induced lowering of intracellular pH on rabbit esophageal epithelial cells. Gastroenterology 105, 1035-1044.[Medline]

Vaupel, P (1996). Is there a critical tissue oxygen tension for bioenergetic status and cellular pH regulation in solid tumors. Experientia 52, 464-468.[Medline]

Velazquez, O. C., Lederer, H. M. and Rombeau, J. L (1996). Butyrate and the colonocyte. Dig. Dis. Sci 41, 727-739.[Medline]

White, M. W (1992). Metabolism of the malignant cell, in vivo is anaerobic and plays a significantrole in the pathway to carcinogenesis. Med. Hypoth 39, 323-333.[Medline]

Zweibaum, A., Pinto, M., Chevalier, G., Dussaulx, E., Triadou, N., LaCroix, B., Haffen, K., Brun, J.-L. and Rousset, M (1985). Enterocytic differentiation of a subpopulation of the human colon tumor line HT-29 selected for growth in sugar-free medium and its inhibition by glucose. J. Cell. Physiol 122, 21-29.[Medline]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

J. Kong, H. Nakagawa, B. K. Isariyawongse, S. Funakoshi, D. G. Silberg, A. K. Rustgi, and J. P. Lynch
Induction of intestinalization in human esophageal keratinocytes is a multistep process
Carcinogenesis, January 1, 2009; 30(1): 122 - 130.
[Abstract] [Full Text] [PDF]

K. Dvorak, C. M Payne, M. Chavarria, L. Ramsey, B. Dvorakova, H. Bernstein, H. Holubec, R. E Sampliner, N. Guy, A. Condon, et al.
Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus
Gut, June 1, 2007; 56(6): 763 - 771.
[Abstract] [Full Text] [PDF]

R C Fitzgerald
Molecular basis of Barrett's oesophagus and oesophageal adenocarcinoma.
Gut, December 1, 2006; 55(12): 1810 - 1820.
[Full Text] [PDF]

B A Onwuegbusi, A Aitchison, S-F Chin, T Kranjac, I Mills, Y Huang, P Lao-Sirieix, C Caldas, and R C Fitzgerald
Impaired transforming growth factor {beta} signalling in Barrett's carcinogenesis due to frequent SMAD4 inactivation
Gut, June 1, 2006; 55(6): 764 - 774.
[Abstract] [Full Text] [PDF]

S. P. Duggan, W. M. Gallagher, E. J.P. Fox, M. M. Abdel-Latif, J. V. Reynolds, and D. Kelleher
Low pH induces co-ordinate regulation of gene expression in oesophageal cells
Carcinogenesis, February 1, 2006; 27(2): 319 - 327.
[Abstract] [Full Text] [PDF]

G. A. Sarosi Jr., K. Jaiswal, E. Herndon, C. Lopez-Guzman, S. J. Spechler, and R. F. Souza
Acid increases MAPK-mediated proliferation in Barrett's esophageal adenocarcinoma cells via intracellular acidification through a Cl-/HCO3- exchanger
Am J Physiol Gastrointest Liver Physiol, December 1, 2005; 289(6): G991 - G996.
[Abstract] [Full Text] [PDF]

M. Marchetti, E. Caliot, and E. Pringault
Chronic acid exposure leads to activation of the cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytes
J. Cell Sci., April 15, 2003; 116(8): 1429 - 1436.
[Abstract] [Full Text] [PDF]

T. Takahashi, B. Lord, P. C. Schulze, R. M. Fryer, S. S. Sarang, S. R. Gullans, and R. T. Lee
Ascorbic Acid Enhances Differentiation of Embryonic Stem Cells Into Cardiac Myocytes
Circulation, April 15, 2003; 107(14): 1912 - 1916.
[Abstract] [Full Text] [PDF]

U. Klahre, E. Friederich, B. Kost, D. Louvard, and N.-H. Chua
Villin-Like Actin-Binding Proteins Are Expressed Ubiquitously in Arabidopsis
Plant Physiology, January 1, 2000; 122(1): 35 - 48.
[Abstract] [Full Text] [PDF]

E Cohen, I Ophir, and Y. Shaul
Induced differentiation in HT29, a human colon adenocarcinoma cell line
J. Cell Sci., January 8, 1999; 112(16): 2657 - 2666.
[Abstract] [PDF]

R. C. Fitzgerald, M. B. Omary, and G. Triadafilopoulos
Altered sodium-hydrogen exchange activity is a mechanism for acid-induced hyperproliferation in Barrett's esophagus
Am J Physiol Gastrointest Liver Physiol, July 1, 1998; 275(1): G47 - G55.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Fitzgerald, R. C.

Articles by Triadafilopoulos, G.

Search for Related Content

PubMed

PubMed Citation

Articles by Fitzgerald, R. C.

Articles by Triadafilopoulos, G.

Social Bookmarking

What's this?

				K. Dvorak, C. M Payne, M. Chavarria, L. Ramsey, B. Dvorakova, H. Bernstein, H. Holubec, R. E Sampliner, N. Guy, A. Condon, et al. Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus Gut, June 1, 2007; 56(6): 763 - 771. [Abstract] [Full Text] [PDF]

				R C Fitzgerald Molecular basis of Barrett's oesophagus and oesophageal adenocarcinoma. Gut, December 1, 2006; 55(12): 1810 - 1820. [Full Text] [PDF]

				B A Onwuegbusi, A Aitchison, S-F Chin, T Kranjac, I Mills, Y Huang, P Lao-Sirieix, C Caldas, and R C Fitzgerald Impaired transforming growth factor {beta} signalling in Barrett's carcinogenesis due to frequent SMAD4 inactivation Gut, June 1, 2006; 55(6): 764 - 774. [Abstract] [Full Text] [PDF]

				S. P. Duggan, W. M. Gallagher, E. J.P. Fox, M. M. Abdel-Latif, J. V. Reynolds, and D. Kelleher Low pH induces co-ordinate regulation of gene expression in oesophageal cells Carcinogenesis, February 1, 2006; 27(2): 319 - 327. [Abstract] [Full Text] [PDF]

				G. A. Sarosi Jr., K. Jaiswal, E. Herndon, C. Lopez-Guzman, S. J. Spechler, and R. F. Souza Acid increases MAPK-mediated proliferation in Barrett's esophageal adenocarcinoma cells via intracellular acidification through a Cl-/HCO3- exchanger Am J Physiol Gastrointest Liver Physiol, December 1, 2005; 289(6): G991 - G996. [Abstract] [Full Text] [PDF]

				M. Marchetti, E. Caliot, and E. Pringault Chronic acid exposure leads to activation of the cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytes J. Cell Sci., April 15, 2003; 116(8): 1429 - 1436. [Abstract] [Full Text] [PDF]

				T. Takahashi, B. Lord, P. C. Schulze, R. M. Fryer, S. S. Sarang, S. R. Gullans, and R. T. Lee Ascorbic Acid Enhances Differentiation of Embryonic Stem Cells Into Cardiac Myocytes Circulation, April 15, 2003; 107(14): 1912 - 1916. [Abstract] [Full Text] [PDF]

				U. Klahre, E. Friederich, B. Kost, D. Louvard, and N.-H. Chua Villin-Like Actin-Binding Proteins Are Expressed Ubiquitously in Arabidopsis Plant Physiology, January 1, 2000; 122(1): 35 - 48. [Abstract] [Full Text] [PDF]

				E Cohen, I Ophir, and Y. Shaul Induced differentiation in HT29, a human colon adenocarcinoma cell line J. Cell Sci., January 8, 1999; 112(16): 2657 - 2666. [Abstract] [PDF]

				R. C. Fitzgerald, M. B. Omary, and G. Triadafilopoulos Altered sodium-hydrogen exchange activity is a mechanism for acid-induced hyperproliferation in Barrett's esophagus Am J Physiol Gastrointest Liver Physiol, July 1, 1998; 275(1): G47 - G55. [Abstract] [Full Text] [PDF]