Retargeting of cytosolic proteins to the plasma membrane by the Lck protein tyrosine kinase dual acylation motif

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Zlatkine, P.
	Articles by Magee, A. I.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Zlatkine, P.
	Articles by Magee, A. I.


Social Bookmarking

	What's this?

Alland, L., Peseckis, S. M., Atherton, R. E., Berthiaume, L. and Resh, M. D (1994). Dual myristylation and palmitylation of Src family member p59 fyn affects subcellular localisation. J. Biol. Chem 269, 16701-16705.[Abstract/Free Full Text]

Bohuslav, J., Cinek, T. and Horejsi, V (1993). Large, detergent-resistant complexes containing murine antigen Thy-1 and Ly-6 and protein tyrosine kinase p56 lck. Eur. J. Immunol 23, 825-831.[Medline]

Danielsen, E. M. and van Deurs, B (1995). A transferrin-like GPI-linked iron-binding protein in detergent-insoluble noncaveolar microdomains at the apical surface of fetal intestinal epithelial cells. J. Cell Biol 131, 939-950.[Abstract/Free Full Text]

Field, K. A., Holowka, D. and Baird, B (1995). FcRI-mediated recruitment of p53/56lynto detergent-resistant membrane domains accompanies cellular signaling. Proc. Nat. Acad. Sci. USA 92, 9201-9205.[Abstract/Free Full Text]

Fra, A. M., Williamson, E., Simons, K. and Parton, R. G (1994). Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolin. J. Biol. Chem 269, 30745-30748.[Abstract/Free Full Text]

Fra, A. M., Williamson, E., Simons, K. and Parton, R. G (1995). De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin. Proc. Nat. Acad. Sci. USA 92, 8655-8659.[Abstract/Free Full Text]

Gorodinsky, A. and Harris, D. A (1995). Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin. J. Cell Biol 129, 619-627.[Abstract/Free Full Text]

Hancock, J. F., Magee, A. I., Childs, J. E. and Marshall, C. J (1989). All ras proteins are palmitoylated but only some are polyisoprenylated. Cell 57, 1167-1177.[Medline]

Hancock, J. F., Paterson, H. and Marshall, C. J (1990). A polybasic domain or palmitoylation is required in addition to the CAAX motif to localise p21rasto the plasma membrane. Cell 63, 133-139.[Medline]

Huang, D. C. S., Marshall, C. J. and Hancock, J. F (1993). Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21 ras function. Mol. Cell. Biol 13, 2420-2431.[Abstract/Free Full Text]

Koegl, M., Zlatkine, P., Ley, S. C., Courtneidge, S. A. and Magee, A. I (1994). Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif. Biochem. J 303, 749-753.

Kwong, J. and Lublin, D. M (1995). Amino-terminal palmitate or polybasic domain can provide required second signal to myristate for membrane binding ofp56lck. Biochem. Biophys. Res. Commun 207, 868-876.[Medline]

Laemmli, U. K (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.[Medline]

Leevers, S. J., Paterson, H. F. and Marshall, C. J (1994). Requirement for ras in raf activation is overcome by targeting raf to the plasma membrane. Nature 369, 411-414.[Medline]

Ley, S. C., Marsh, M., Bebbington, C. R., Proudfoot, K. and Jordan, P (1994). Distinct intracellular localisation of Lck and Fyn protein tyrosine kinases in human T lymphocytes. J. Cell Biol 125, 639-649.[Abstract/Free Full Text]

Magee, A. I., Gutierrez, L., McKay, I. A., Marshall, C. J. and Hall, A (1987). Dynamic fatty acylation of p21N-ras. EMBO J 4, 1137-1144.[Medline]

Magee, A. I., Wootton, J. and de Bony, J (1995). Detecting radiolabeled lipid-modified proteins in polyacrylamide gels. Meth. Enzymol 25, 330-336.

Mayor, S., Rothberg, K. G. and Maxfield, F. R (1994). Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science 264, 1948-1951.[Abstract/Free Full Text]

Mehul, B., Bawumia, S., Martin, S. R. and Hughes, R. C (1994). Structure of baby hamster kidney carbohydrate-binding protein CBP30, an S-type animal lectin. J. Biol. Chem 269, 18250-18258.[Abstract/Free Full Text]

Milligan, G., Parenti, M. and Magee, A. I (1995). The dynamic role of palmitoylation in signal transduction. Trends Biochem. Sci 20, 181-186.[Medline]

Mineo, C., James, G. L., Smart, E. J. and Anderson, R. G. W (1996). Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane. J. Biol. Chem 271, 11930-11935.[Abstract/Free Full Text]

Newman, C. M. H., Giannakouros, T., Hancock, J. F., Fawell, E. H., Armstrong, J. and Magee, A. I (1992). Post-translational processing of Schizosaccharomyces pombe YPT proteins. J. Biol. Chem 267, 11329-11336.[Abstract/Free Full Text]

Paige, L. A., Nadler, M. J. S., Harrison, M. L., Cassady, J. M. and Geahlen, R. L (1993). Reversible palmitoylation of the protein-tyrosine kinase p56 lck. J. Biol. Chem 268, 8669-8674.[Abstract/Free Full Text]

Parenti, M., Vigano, M. A., Newman, C. M. H., Milligan, G. and Magee, A. I (1993). A novel N-terminal motif for palmitoylation of G-proteinsubunits. Biochem. J 291, 349-353.

Quilliam, L. A., Huff, S. Y., Rabun, K. M., Wei, W., Park, W., Broek, D. and Der, C. J (1994). Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity. Proc. Nat. Acad. Sci. USA 91, 8512-8516.[Abstract/Free Full Text]

Resh, M. D (1994). Myristylation and palmitylation of Src family members: the fats of the matter. Cell 76, 411-413.

Rodgers, W., Crise, B. and Rose, J. K (1994). Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored targeting to a glycolipid-enriched membrane fraction. Mol. Cell. Biol 14, 5384-5391.[Abstract/Free Full Text]

Sato, S. and Hughes, R. C (1994). Regulation of secretion and surface expression of Mac-2, a galactoside-binding protein of macrophages. J. Biol. Chem 269, 4424-4430.[Abstract/Free Full Text]

Schnitzer, J. E., McIntosh, D. P., Dvorak, A. M., Liu, J. and Oh, P (1995). Separation of caveolae from associated microdomains of GPI-anchored proteins. Science 269, 1435-1439.[Abstract/Free Full Text]

Shenoy-Scaria, A. M., Gauen, L. K. T., Kwong, J., Shaw, A. S. and Lublin, D. M (1993). Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lckand P59fynmediates interaction with glycosyl-phosphatidylinositol-anchored proteins. Mol. Cell. Biol 13, 6385-6392.[Abstract/Free Full Text]

Shenoy-Scaria, A M., Dietzen, D. J., Kwong, J., Link, D. C. and Lublin, D. M (1994). Cysteine3of Src family protein tyrosine kinases determines palmitoylation and localisation in caveolae. J. Cell Biol 126, 353-363.[Abstract/Free Full Text]

Silverman, L. and Resh, M. D (1992). Lysine residues form an integral component of a novel NH2-terminal membrane targeting motif for myristylated pp60v-src. J. Cell Biol 119, 415-425.[Abstract/Free Full Text]

Song, K. S., Li, S., Okamoto, T., Quilliam, L. A., Sargiacomo, M. and Lisanti, M. P (1996). Co-purification and direct interaction of ras with caveolin, an integral membrane protein of caveolae microdomains. J. Biol. Chem 271, 9690-9697.[Abstract/Free Full Text]

Stokoe, D., Macdonald, S. G., Cadwallader, K., Symons, M. and Hancock, J. F (1994). Activation of Raf as a result of recruitment to the plasma membrane. Science 264, 1463-1467.[Abstract/Free Full Text]

Turner, J. M., Brodsky, M. H., Irving, B. A., Levin, S. D., Perlmutter, R. M. and Littman, D. R (1990). Interaction of the unique N-terminal region of tyrosine kinase p56 lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs. Cell 60, 755-765.[Medline]

Zhou, M.-j., Lublin, D. M., Link, D. C. and Brown, E (1995). Distinct tyrosine kinase activation and Triton X-100 insolubility upon FcRII or Fc RIIIB ligation in human polymorphonuclear leukocytes. J. Biol. Chem 270, 13553-13560.[Abstract/Free Full Text]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

S. Rigby, Y. Huang, B. Streubel, A. Chott, M.-Q. Du, S. D. Turner, and C. M. Bacon
The Lymphoma-associated Fusion Tyrosine Kinase ITK-SYK Requires Pleckstrin Homology Domain-mediated Membrane Localization for Activation and Cellular Transformation
J. Biol. Chem., September 25, 2009; 284(39): 26871 - 26881.
[Abstract] [Full Text] [PDF]

B. F. Lillemeier, J. R. Pfeiffer, Z. Surviladze, B. S. Wilson, and M. M. Davis
Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton
PNAS, December 12, 2006; 103(50): 18992 - 18997.
[Abstract] [Full Text] [PDF]

Z. Tiran, A. Peretz, T. Sines, V. Shinder, J. Sap, B. Attali, and A. Elson
Tyrosine Phosphatases {varepsilon} and {alpha} Perform Specific and Overlapping Functions in Regulation of Voltage-gated Potassium Channels in Schwann Cells
Mol. Biol. Cell, October 1, 2006; 17(10): 4330 - 4342.
[Abstract] [Full Text] [PDF]

B. W. Wattenberg, S. M. Pitson, and D. M. Raben
The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function
J. Lipid Res., June 1, 2006; 47(6): 1128 - 1139.
[Abstract] [Full Text] [PDF]

M. Zhang, M. Moran, J. Round, T. A. Low, V. P. Patel, T. Tomassian, J. D. Hernandez, and M. C. Miceli
CD45 Signals outside of Lipid Rafts to Promote ERK Activation, Synaptic Raft Clustering, and IL-2 Production
J. Immunol., February 1, 2005; 174(3): 1479 - 1490.
[Abstract] [Full Text] [PDF]

S. M. Pitson, P. Xia, T. M. Leclercq, P. A.B. Moretti, J. R. Zebol, H. E. Lynn, B. W. Wattenberg, and M. A. Vadas
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling
J. Exp. Med., January 3, 2005; 201(1): 49 - 54.
[Abstract] [Full Text] [PDF]

D. W. O'Callaghan, B. Hasdemir, M. Leighton, and R. D. Burgoyne
Residues within the myristoylation motif determine intracellular targeting of the neuronal Ca2+ sensor protein KChIP1 to post-ER transport vesicles and traffic of Kv4 K+ channels
J. Cell Sci., December 1, 2003; 116(23): 4833 - 4845.
[Abstract] [Full Text] [PDF]

S. Jordan and W. Rodgers
T Cell Glycolipid-Enriched Membrane Domains Are Constitutively Assembled as Membrane Patches That Translocate to Immune Synapses
J. Immunol., July 1, 2003; 171(1): 78 - 87.
[Abstract] [Full Text] [PDF]

J. Zhou, J. Fandrey, J. Schumann, G. Tiegs, and B. Brune
NO and TNF-alpha released from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells
Am J Physiol Cell Physiol, February 1, 2003; 284(2): C439 - C446.
[Abstract] [Full Text] [PDF]

I. Y. Hawash, K. P. Kesavan, A. I. Magee, R. L. Geahlen, and M. L. Harrison
The Lck SH3 Domain Negatively Regulates Localization to Lipid Rafts through an Interaction with c-Cbl
J. Biol. Chem., February 8, 2002; 277(7): 5683 - 5691.
[Abstract] [Full Text] [PDF]

K. B. Sandau, J. Zhou, T. Kietzmann, and B. Brune
Regulation of the Hypoxia-inducible Factor 1alpha by the Inflammatory Mediators Nitric Oxide and Tumor Necrosis Factor-alpha in Contrast to Desferroxamine and Phenylarsine Oxide
J. Biol. Chem., October 19, 2001; 276(43): 39805 - 39811.
[Abstract] [Full Text] [PDF]

K. Yasuda, A. Kosugi, F. Hayashi, S.-i. Saitoh, M. Nagafuku, Y. Mori, M. Ogata, and T. Hamaoka
Serine 6 of Lck Tyrosine Kinase: A Critical Site for Lck Myristoylation, Membrane Localization, and Function in T Lymphocytes
J. Immunol., September 15, 2000; 165(6): 3226 - 3231.
[Abstract] [Full Text] [PDF]

M.-J. J. E. Bijlmakers and M. Marsh
Hsp90 Is Essential for the Synthesis and Subsequent Membrane Association, But Not the Maintenance, of the Src-Kinase p56lck
Mol. Biol. Cell, May 1, 2000; 11(5): 1585 - 1595.
[Abstract] [Full Text]

C. S. Fishburn, S. K. Pollitt, and H. R. Bourne
Localization of a peripheral membrane protein: Gbeta gamma targets Galpha Z
PNAS, February 1, 2000; 97(3): 1085 - 1090.
[Abstract] [Full Text] [PDF]

D. S. Evanko, M. M. Thiyagarajan, and P. B. Wedegaertner
Interaction with Gbeta gamma Is Required for Membrane Targeting and Palmitoylation of Galpha s and Galpha q
J. Biol. Chem., January 14, 2000; 275(2): 1327 - 1336.
[Abstract] [Full Text] [PDF]

J. B. McCabe and L. G. Berthiaume
Functional Roles for Fatty Acylated Amino-terminal Domains in Subcellular Localization
Mol. Biol. Cell, November 1, 1999; 10(11): 3771 - 3786.
[Abstract] [Full Text]

J. Lin, A. Weiss, and T. S. Finco
Localization of LAT in Glycolipid-enriched Microdomains Is Required for T cell Activation
J. Biol. Chem., October 8, 1999; 274(41): 28861 - 28864.
[Abstract] [Full Text] [PDF]

S. Gonzalo, W. K. Greentree, and M. E. Linder
SNAP-25 Is Targeted to the Plasma Membrane through a Novel Membrane-binding Domain
J. Biol. Chem., July 23, 1999; 274(30): 21313 - 21318.
[Abstract] [Full Text] [PDF]

C. S. Fishburn, P. Herzmark, J. Morales, and H. R. Bourne
Gbeta gamma and Palmitate Target Newly Synthesized Galpha z to the Plasma Membrane
J. Biol. Chem., June 25, 1999; 274(26): 18793 - 18800.
[Abstract] [Full Text] [PDF]

M.-J. J.E. Bijlmakers and M. Marsh
Trafficking of an Acylated Cytosolic Protein: Newly Synthesized p56lck Travels to the Plasma Membrane via the Exocytic Pathway
J. Cell Biol., May 3, 1999; 145(3): 457 - 468.
[Abstract] [Full Text] [PDF]

W. Hof and M. D. Resh
Dual Fatty Acylation of p59Fyn Is Required for Association with the T Cell Receptor {zeta} Chain through Phosphotyrosine-Src Homology Domain-2 Interactions
J. Cell Biol., April 19, 1999; 145(2): 377 - 389.
[Abstract] [Full Text] [PDF]

F. Galbiati, D. Volonte, D. Meani, G. Milligan, D. M. Lublin, M. P. Lisanti, and M. Parenti
The Dually Acylated NH2-terminal Domain of Gi1alpha Is Sufficient to Target a Green Fluorescent Protein Reporter to Caveolin-enriched Plasma Membrane Domains. PALMITOYLATION OF CAVEOLIN-1 IS REQUIRED FOR THE RECOGNITION OF DUALLY ACYLATED G-PROTEIN alpha �SUBUNITS IN VIVO
J. Biol. Chem., February 26, 1999; 274(9): 5843 - 5850.
[Abstract] [Full Text] [PDF]

T.S. FINCO, D. YABLONSKI, J. LIN, and A. WEISS
The Adapter Proteins LAT and SLP-76 Are Required for T-cell Activation
Cold Spring Harb Symp Quant Biol, January 1, 1999; 64(0): 265 - 274.
[Abstract] [PDF]

P. Stanley, V. Koronakis, and C. Hughes
Acylation of Escherichia coli Hemolysin: A Unique Protein Lipidation Mechanism Underlying Toxin Function
Microbiol. Mol. Biol. Rev., June 1, 1998; 62(2): 309 - 333.
[Abstract] [Full Text] [PDF]

J. Morales, C. S. Fishburn, P. T. Wilson, and H. R. Bourne
Plasma Membrane Localization of Galpha z Requires Two Signals
Mol. Biol. Cell, January 1, 1998; 9(1): 1 - 14.
[Abstract] [Full Text]

M. Andjelkovic, D. R. Alessi, R. Meier, A. Fernandez, N. J.�C. Lamb, M. Frech, P. Cron, P. Cohen, J. M. Lucocq, and B. A. Hemmings
Role of Translocation in the Activation and Function of Protein Kinase B
J. Biol. Chem., December 12, 1997; 272(50): 31515 - 31524.
[Abstract] [Full Text] [PDF]

R. D.J. Huby, M. Iwashima, A. Weiss, and S. C. Ley
ZAP-70 Protein Tyrosine Kinase Is Constitutively Targeted to the T Cell Cortex Independently of its SH2 Domains
J. Cell Biol., June 30, 1997; 137(7): 1639 - 1649.
[Abstract] [Full Text] [PDF]

B Mehul and R. Hughes
Plasma membrane targetting, vesicular budding and release of galectin 3 from the cytoplasm of mammalian cells during secretion
J. Cell Sci., January 5, 1997; 110(10): 1169 - 1178.
[Abstract] [PDF]

S. Strack, A. J. Robison, M. A. Bass, and R. J. Colbran
Association of Calcium/Calmodulin-dependent Kinase II with Developmentally Regulated Splice Variants of the Postsynaptic Density Protein Densin-180
J. Biol. Chem., August 11, 2000; 275(33): 25061 - 25064.
[Abstract] [Full Text] [PDF]

S. Carreno, M.-E. Gouze, S. Schaak, L. J. Emorine, and I. Maridonneau-Parini
Lack of Palmitoylation Redirects p59Hck from the Plasma Membrane to p61Hck-positive Lysosomes
J. Biol. Chem., November 10, 2000; 275(46): 36223 - 36229.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Zlatkine, P.

Articles by Magee, A. I.

Search for Related Content

PubMed

PubMed Citation

Articles by Zlatkine, P.

Articles by Magee, A. I.

Social Bookmarking

What's this?

				B. F. Lillemeier, J. R. Pfeiffer, Z. Surviladze, B. S. Wilson, and M. M. Davis Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton PNAS, December 12, 2006; 103(50): 18992 - 18997. [Abstract] [Full Text] [PDF]

				Z. Tiran, A. Peretz, T. Sines, V. Shinder, J. Sap, B. Attali, and A. Elson Tyrosine Phosphatases {varepsilon} and {alpha} Perform Specific and Overlapping Functions in Regulation of Voltage-gated Potassium Channels in Schwann Cells Mol. Biol. Cell, October 1, 2006; 17(10): 4330 - 4342. [Abstract] [Full Text] [PDF]

				B. W. Wattenberg, S. M. Pitson, and D. M. Raben The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function J. Lipid Res., June 1, 2006; 47(6): 1128 - 1139. [Abstract] [Full Text] [PDF]

				M. Zhang, M. Moran, J. Round, T. A. Low, V. P. Patel, T. Tomassian, J. D. Hernandez, and M. C. Miceli CD45 Signals outside of Lipid Rafts to Promote ERK Activation, Synaptic Raft Clustering, and IL-2 Production J. Immunol., February 1, 2005; 174(3): 1479 - 1490. [Abstract] [Full Text] [PDF]

				S. M. Pitson, P. Xia, T. M. Leclercq, P. A.B. Moretti, J. R. Zebol, H. E. Lynn, B. W. Wattenberg, and M. A. Vadas Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling J. Exp. Med., January 3, 2005; 201(1): 49 - 54. [Abstract] [Full Text] [PDF]

				D. W. O'Callaghan, B. Hasdemir, M. Leighton, and R. D. Burgoyne Residues within the myristoylation motif determine intracellular targeting of the neuronal Ca2+ sensor protein KChIP1 to post-ER transport vesicles and traffic of Kv4 K+ channels J. Cell Sci., December 1, 2003; 116(23): 4833 - 4845. [Abstract] [Full Text] [PDF]

				S. Jordan and W. Rodgers T Cell Glycolipid-Enriched Membrane Domains Are Constitutively Assembled as Membrane Patches That Translocate to Immune Synapses J. Immunol., July 1, 2003; 171(1): 78 - 87. [Abstract] [Full Text] [PDF]

				J. Zhou, J. Fandrey, J. Schumann, G. Tiegs, and B. Brune NO and TNF-alpha released from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells Am J Physiol Cell Physiol, February 1, 2003; 284(2): C439 - C446. [Abstract] [Full Text] [PDF]

				I. Y. Hawash, K. P. Kesavan, A. I. Magee, R. L. Geahlen, and M. L. Harrison The Lck SH3 Domain Negatively Regulates Localization to Lipid Rafts through an Interaction with c-Cbl J. Biol. Chem., February 8, 2002; 277(7): 5683 - 5691. [Abstract] [Full Text] [PDF]

				K. B. Sandau, J. Zhou, T. Kietzmann, and B. Brune Regulation of the Hypoxia-inducible Factor 1alpha by the Inflammatory Mediators Nitric Oxide and Tumor Necrosis Factor-alpha in Contrast to Desferroxamine and Phenylarsine Oxide J. Biol. Chem., October 19, 2001; 276(43): 39805 - 39811. [Abstract] [Full Text] [PDF]

				K. Yasuda, A. Kosugi, F. Hayashi, S.-i. Saitoh, M. Nagafuku, Y. Mori, M. Ogata, and T. Hamaoka Serine 6 of Lck Tyrosine Kinase: A Critical Site for Lck Myristoylation, Membrane Localization, and Function in T Lymphocytes J. Immunol., September 15, 2000; 165(6): 3226 - 3231. [Abstract] [Full Text] [PDF]

				M.-J. J. E. Bijlmakers and M. Marsh Hsp90 Is Essential for the Synthesis and Subsequent Membrane Association, But Not the Maintenance, of the Src-Kinase p56lck Mol. Biol. Cell, May 1, 2000; 11(5): 1585 - 1595. [Abstract] [Full Text]

				C. S. Fishburn, S. K. Pollitt, and H. R. Bourne Localization of a peripheral membrane protein: Gbeta gamma targets Galpha Z PNAS, February 1, 2000; 97(3): 1085 - 1090. [Abstract] [Full Text] [PDF]

				D. S. Evanko, M. M. Thiyagarajan, and P. B. Wedegaertner Interaction with Gbeta gamma Is Required for Membrane Targeting and Palmitoylation of Galpha s and Galpha q J. Biol. Chem., January 14, 2000; 275(2): 1327 - 1336. [Abstract] [Full Text] [PDF]

				J. B. McCabe and L. G. Berthiaume Functional Roles for Fatty Acylated Amino-terminal Domains in Subcellular Localization Mol. Biol. Cell, November 1, 1999; 10(11): 3771 - 3786. [Abstract] [Full Text]

				J. Lin, A. Weiss, and T. S. Finco Localization of LAT in Glycolipid-enriched Microdomains Is Required for T cell Activation J. Biol. Chem., October 8, 1999; 274(41): 28861 - 28864. [Abstract] [Full Text] [PDF]

				S. Gonzalo, W. K. Greentree, and M. E. Linder SNAP-25 Is Targeted to the Plasma Membrane through a Novel Membrane-binding Domain J. Biol. Chem., July 23, 1999; 274(30): 21313 - 21318. [Abstract] [Full Text] [PDF]

				C. S. Fishburn, P. Herzmark, J. Morales, and H. R. Bourne Gbeta gamma and Palmitate Target Newly Synthesized Galpha z to the Plasma Membrane J. Biol. Chem., June 25, 1999; 274(26): 18793 - 18800. [Abstract] [Full Text] [PDF]

				M.-J. J.E. Bijlmakers and M. Marsh Trafficking of an Acylated Cytosolic Protein: Newly Synthesized p56lck Travels to the Plasma Membrane via the Exocytic Pathway J. Cell Biol., May 3, 1999; 145(3): 457 - 468. [Abstract] [Full Text] [PDF]

				W. Hof and M. D. Resh Dual Fatty Acylation of p59Fyn Is Required for Association with the T Cell Receptor {zeta} Chain through Phosphotyrosine-Src Homology Domain-2 Interactions J. Cell Biol., April 19, 1999; 145(2): 377 - 389. [Abstract] [Full Text] [PDF]

				F. Galbiati, D. Volonte, D. Meani, G. Milligan, D. M. Lublin, M. P. Lisanti, and M. Parenti The Dually Acylated NH2-terminal Domain of Gi1alpha Is Sufficient to Target a Green Fluorescent Protein Reporter to Caveolin-enriched Plasma Membrane Domains. PALMITOYLATION OF CAVEOLIN-1 IS REQUIRED FOR THE RECOGNITION OF DUALLY ACYLATED G-PROTEIN alpha �SUBUNITS IN VIVO J. Biol. Chem., February 26, 1999; 274(9): 5843 - 5850. [Abstract] [Full Text] [PDF]

				T.S. FINCO, D. YABLONSKI, J. LIN, and A. WEISS The Adapter Proteins LAT and SLP-76 Are Required for T-cell Activation Cold Spring Harb Symp Quant Biol, January 1, 1999; 64(0): 265 - 274. [Abstract] [PDF]

				P. Stanley, V. Koronakis, and C. Hughes Acylation of Escherichia coli Hemolysin: A Unique Protein Lipidation Mechanism Underlying Toxin Function Microbiol. Mol. Biol. Rev., June 1, 1998; 62(2): 309 - 333. [Abstract] [Full Text] [PDF]

				J. Morales, C. S. Fishburn, P. T. Wilson, and H. R. Bourne Plasma Membrane Localization of Galpha z Requires Two Signals Mol. Biol. Cell, January 1, 1998; 9(1): 1 - 14. [Abstract] [Full Text]

				M. Andjelkovic, D. R. Alessi, R. Meier, A. Fernandez, N. J.�C. Lamb, M. Frech, P. Cron, P. Cohen, J. M. Lucocq, and B. A. Hemmings Role of Translocation in the Activation and Function of Protein Kinase B J. Biol. Chem., December 12, 1997; 272(50): 31515 - 31524. [Abstract] [Full Text] [PDF]

				R. D.J. Huby, M. Iwashima, A. Weiss, and S. C. Ley ZAP-70 Protein Tyrosine Kinase Is Constitutively Targeted to the T Cell Cortex Independently of its SH2 Domains J. Cell Biol., June 30, 1997; 137(7): 1639 - 1649. [Abstract] [Full Text] [PDF]

				B Mehul and R. Hughes Plasma membrane targetting, vesicular budding and release of galectin 3 from the cytoplasm of mammalian cells during secretion J. Cell Sci., January 5, 1997; 110(10): 1169 - 1178. [Abstract] [PDF]

				S. Strack, A. J. Robison, M. A. Bass, and R. J. Colbran Association of Calcium/Calmodulin-dependent Kinase II with Developmentally Regulated Splice Variants of the Postsynaptic Density Protein Densin-180 J. Biol. Chem., August 11, 2000; 275(33): 25061 - 25064. [Abstract] [Full Text] [PDF]

				S. Carreno, M.-E. Gouze, S. Schaak, L. J. Emorine, and I. Maridonneau-Parini Lack of Palmitoylation Redirects p59Hck from the Plasma Membrane to p61Hck-positive Lysosomes J. Biol. Chem., November 10, 2000; 275(46): 36223 - 36229. [Abstract] [Full Text] [PDF]