Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

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Boocock, C. A., Jones, G. E., Stanley, E. R. and Pollard, J. W (1989). Colony stimulating factor-1 induces rapid behavioural responses in the mouse macrophage cell lines, Bac1. J. Cell Sci 93, 447-456.[Abstract/Free Full Text]

Burridge, K., Fath, K., Kelly, T., Nuckolls, G. and Turner, C (1988). Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol 4, 487-525.

Choi, K., Kennedy, M. and Keller, G (1993). Expression of a gene encoding a unique protein-tyrosine kinase within specific fetal-and adult-derived hematopoietic lineages. Proc. Nat. Acad. Sci. USA 90, 5747-5751.[Abstract/Free Full Text]

Chrzanowska-Wodnicka, M. and Burridge, K (1996). Rho-stimulated contractility drives the formation of stress fibres and focal adhesions. J. Cell Biol 133, 1403-1415.[Abstract/Free Full Text]

de Nichilo, M. O. and Burns, G. F (1993). Granulocyte-macrophage and macrophage colony-stimulating factors differentially regulatev integrin expression on cultured human macrophages. Proc. Nat. Acad. Sci. USA 90, 2517-2521.[Abstract/Free Full Text]

de Nichilo, M. O. and Yamada, K. M (1996). Integrinv 5-dependent serine phosphorylation of paxillin in cultured human macrophages adherent to vitronectin. J. Biol. Chem 271, 11016-11022.[Abstract/Free Full Text]

Downey, G. P (1994). Mechanisms of leukocyte motility and chemotaxis. Curr. Opin. Immunol 6, 113-124.[Medline]

Dutartre, H., Davoust, J., Gorvel, J.-P. and Chavrier, P (1996). Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs. J. Cell Sci 109, 367-377.[Abstract]

Flinn, H. M. and Ridley, A. J (1996). Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin. J. Cell Sci 109, 1133-1141.[Abstract]

Hall, A. and Self, A. J (1986). The effect of Mg2+on the guanine nucleotide exchange rate of p21 N-ras. J. Biol. Chem 261, 10963-10965.[Abstract/Free Full Text]

Hall, A (1994). Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu. Rev. Cell Biol 10, 31-54.

Hartwig, J. H., Bokoch, G. M., Carpenter, C. L., Janmey, P. A., Taylor, L. A., Toker, A. and Stossel, T. P (1995). Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell 82, 643-653.[Medline]

Hotchin, N. A. and Hall, A (1995). The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases. J. Cell Biol 131, 1857-1865.[Abstract/Free Full Text]

Huttenlocher, A., Sandborg, R. R. and Horwitz, A. F (1995). Adhesion in cell migration. Curr. Opin. Cell Biol 7, 697-706.[Medline]

Jalink, K., van Corven, E. J., Hengeveld, T., Morii, N., Narumiya, S. and Moolenaar, W. H (1994). Inhibition of lysophosphatidate-and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J. Cell Biol 126, 801-810.[Abstract/Free Full Text]

Jockush, B. M., Bubeck, P., Giehl, K., Kroemker, M., Moschner, J., Rothkegel, M., Rudiger, M., Schluter, K., Stanke, G. and Winkler, J (1995). The molecular architecture of focal adhesions. Annu. Rev. Cell Dev. Biol 11, 379-416.[Medline]

Kharbanda, S., Saleem, A., Yuan, Z., Emoto, Y., Prasad, E. V. S. and Kufe, D (1995). Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAKand dynamin. Proc. Nat. Acad. Sci. USA 92, 6132-6136.[Abstract/Free Full Text]

Kimura, K., Ito, M., Amano, K., Chihara, K., Fukata, Y., Nakafuku, M., Yamamori, B., Feng, J., Nakano, T., Okawa, K., Iwamatsu, A. and Kaibuchi, K (1996). Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273, 245-248.[Abstract]

Kozma, R., Ahmed, S., Best, A. and Lim, L (1995). The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts. Mol. Cell. Biol 15, 1942-1952.[Abstract]

Lauffenburger, D. A. and Horwitz, A. F (1996). Cell migration: a physically integrated molecular process. Cell 84, 359-369.[Medline]

Leung, T., Chen, X.-Q., Manser, E. and Lim, L (1996). The p160 RhoA-binding kinase ROKa is a member of a kinase family and is involved in the reorganization of the cytoskeleton. Mol. Cell. Biol 16, 5313-5327.[Abstract]

Lin, T. H., Yurochko, A., Kornberg, L., Morris, J., Walker, J. J., Haskill, S. and Juliano, R. L (1994). The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes. J. Cell Biol 126, 1585-1593.[Abstract/Free Full Text]

Lin, T. H., Rosales, C., Mondal, K., Bolen, J. B., Haskill, S. and Juliano, R. L (1995). Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. J. Biol. Chem 270, 16189-16197.[Abstract/Free Full Text]

Matsui, T., Amano, M., Yamamoto, T., Chihara, K., Nakafuku, M., Ito, M., Nakano, T., Okawa, K., Iwamatsu, A. and Kaibuchi, K (1996). Rho-associated kinase, a novel serine/threonine kinase, as a putative target for the small GTP binding protein Rho. EMBO J 15, 2208-2216.[Medline]

Mitchison, T. J. and Cramer, L. P (1996). Actin-based cell motility and cell locomotion. Cell 84, 371-379.[Medline]

Miyamoto, S., Teramoto, H., Coso, O. A., Gutkind, J. S., Burbelo, P. D., Akiyama, S. K. and Yamada, K. M (1995). Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J. Cell Biol 131, 791-805.[Abstract/Free Full Text]

Morgan, C., Pollard, J. W. and Stanley, E. R (1987). Isolation and characterization of a cloned growth factor dependent macrophage cell line, Bac1. J. Cell. Physiol 130, 420-427.[Medline]

Morii, N., Teru-uchi, T., Tominaga, T, Kumagai, N., Kozaki, S., Ushikubi, F. and Narumiya S (1992). A rho gene product in human blood platelets. II. Effects of the ADP-ribosylation by Botulinum C3 ADP-ribosyltransferase on platelet aggregation. J. Biol. Chem 267, 20921-20926.[Abstract/Free Full Text]

Nishiyama, T., Sasaki, T., Takaishi, K., Kato, M., Yaku, H., Araki, K., Matsuura, Y. and Takai, Y (1994). rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor-and 12- 0 -tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells. Mol. Cell. Biol 14, 2447-2456.[Abstract/Free Full Text]

Nobes, C. D. and Hall, A (1995). Rho, Rac and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62.[Medline]

Postma, F. R., Jalink, K., Hengeveld, T. and Moolenaar, W. H (1996). Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor. EMBO J 15, 2388-2395.[Medline]

Ridley, A. J. and Hall, A (1992). The small GTP-binding protein Rho regulates the assembly of focal adhesions and stress fibres in response to growth factors. Cell 70, 389-399.[Medline]

Ridley, A. J., Paterson, H. F., Johnston, C. L., Diekmann, D. and Hall, A (1992). The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410.[Medline]

Ridley, A. J (1995). Rho-related proteins: actin cytoskeleton and cell cycle. Curr. Opin. Genet. Dev 5, 24-30.[Medline]

Ridley, A. J (1995). Rac and Bcr regulate phagocytic phoxes. Curr. Biol 5, 710-712.[Medline]

Ridley, A. J., Comoglio, P. M. and Hall, A (1995). Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac and Rho proteins in MDCK cells. Mol. Cell. Biol 15, 1110-1122.[Abstract]

Ridley, A. J (1996). Rho: theme and variations. Curr. Biol 6, 1256-1264.[Medline]

Rosen, A., Keenan, K. F., Thelen, M., Nairn, A. C. and Aderem, A (1990). Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia. J. Exp. Med 172, 1211-1215.[Abstract/Free Full Text]

Self, A. J. and Hall, A (1995). Purification of recombinant Rho/Rac/G25K from Escherichia coli. Meth. Enzymol 256, 3-10.[Medline]

Symons, M., Derry, J. M. J., Karlak, B., Jiang, S., Lemahieu, V., McCormick, F., Francke, U. and Abo, A (1996). Wiskott-Aldrich Syndrome protein, a novel effector for the GTPase Cdc42Hs, is implicated in actin polymerization. Cell 84, 723-734.[Medline]

Tan, J. L., Ravid, S. and Spudich, J. A (1992). Control of nonmuscle myosins by phosphorylation. Annu. Rev. Biochem 61, 721-759.[Medline]

Tominaga, T., Sugie, K., Hirata, M., Morii, N., Fukata, J., Uchida, A., Imura, H. and Narumiya, S (1993). Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP-ribosylation of the small molecular weight GTP-binding protein, Rho. J. Cell Biol 111, 2097-2108.[Abstract/Free Full Text]

van Aelst, L., Joneson, T. and Bar-Sagi, D (1996). Identification of a novel Rac1-interacting protein involved in membrane ruffling. EMBO J 15, 3778-3786.[Medline]

von Eichel-Streiber, C., Boquet, P., Sauerborn, M. and Thelestam, M (1996). Large clostridial cytotoxins \320 a family of glycosyltransferases modifying small GTP-binding proteins. Trends Microbiol 4, 375-382.[Medline]

Webb, S. E., Pollard, J. W. and Jones, G. E (1996). Direct observation and quantification of macrophage chemoattraction to the growth factor CSF-1. J. Cell. Sci 109, 793-803.[Abstract]

Wojciak-Stothard, B., Curtis, A., Monaghan, W., MacDonald, K. and Wilkinson, C (1996). Guidance and activation of murine macrophages by nanometric scale topography. Exp. Cell Res 223, 426-435.[Medline]

Zhang, D., Udagawa, N., Nakamura, I., Murakami, H., Saito, S., Yamasaki, K., Shibasaki, Y., Morii, N., Narumiya, S., Takahashi, N. and Suda, T (1995). The small GTP-binding protein, rho p21, is involved in bone resorption by regulating cytoskeletal organization in osteoclasts. J. Cell Sci 108, 2285-2292.[Abstract]

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Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration
J. Cell Sci., March 1, 2004; 117(7): 1259 - 1268.
[Abstract] [Full Text] [PDF]

K. Kurokawa, R. E. Itoh, H. Yoshizaki, Y. O. T. Nakamura, and M. Matsuda
Coactivation of Rac1 and Cdc42 at Lamellipodia and Membrane Ruffles Induced by Epidermal Growth Factor
Mol. Biol. Cell, March 1, 2004; 15(3): 1003 - 1010.
[Abstract] [Full Text] [PDF]

A. N. Abell, A. M. DeCathelineau, S. A. Weed, D. R. Ambruso, D. W. Riches, and G. L. Johnson
Rac2D57N, a dominant inhibitory Rac2 mutant that inhibits p38 kinase signaling and prevents surface ruffling in bone-marrow-derived macrophages
J. Cell Sci., January 15, 2004; 117(2): 243 - 255.
[Abstract] [Full Text] [PDF]

A. Y. Kolyada, K. N. Riley, and I. M. Herman
Rho GTPase signaling modulates cell shape and contractile phenotype in an isoactin-specific manner
Am J Physiol Cell Physiol, November 1, 2003; 285(5): C1116 - C1121.
[Abstract] [Full Text] [PDF]

D. Pradip, X. Peng, and D. L. Durden
Rac2 Specificity in Macrophage Integrin Signaling: POTENTIAL ROLE FOR Syk KINASE
J. Biol. Chem., October 24, 2003; 278(43): 41661 - 41669.
[Abstract] [Full Text] [PDF]

D. Gregg, F. M. Rauscher, and P. J. Goldschmidt-Clermont
Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch
Am J Physiol Cell Physiol, October 1, 2003; 285(4): C723 - C734.
[Abstract] [Full Text] [PDF]

M. Okigaki, C. Davis, M. Falasca, S. Harroch, D. P. Felsenfeld, M. P. Sheetz, and J. Schlessinger
Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration
PNAS, September 16, 2003; 100(19): 10740 - 10745.
[Abstract] [Full Text] [PDF]

C. L. Rocha, J. Coburn, E. A. Rucks, and J. C. Olson
Characterization of Pseudomonas aeruginosa Exoenzyme S as a Bifunctional Enzyme in J774A.1 Macrophages
Infect. Immun., September 1, 2003; 71(9): 5296 - 5305.
[Abstract] [Full Text] [PDF]

P. Neumeister, F. J. Pixley, Y. Xiong, H. Xie, K. Wu, A. Ashton, M. Cammer, A. Chan, M. Symons, E. R. Stanley, et al.
Cyclin D1 Governs Adhesion and Motility of Macrophages
Mol. Biol. Cell, May 1, 2003; 14(5): 2005 - 2015.
[Abstract] [Full Text] [PDF]

R. A. Worthylake and K. Burridge
RhoA and ROCK Promote Migration by Limiting Membrane Protrusions
J. Biol. Chem., April 4, 2003; 278(15): 13578 - 13584.
[Abstract] [Full Text] [PDF]

S. H. Wilson, A. V. Ljubimov, A. O. Morla, S. Caballero, L. C. Shaw, P. E. Spoerri, R. W. Tarnuzzer, and M. B. Grant
Fibronectin Fragments Promote Human Retinal Endothelial Cell Adhesion and Proliferation and ERK Activation through {alpha}5{beta}1 Integrin and PI 3-Kinase
Invest. Ophthalmol. Vis. Sci., April 1, 2003; 44(4): 1704 - 1715.
[Abstract] [Full Text] [PDF]

B. Butler, M. P. Williams, and S. D. Blystone
Ligand-dependent Activation of Integrin alpha vbeta 3
J. Biol. Chem., February 7, 2003; 278(7): 5264 - 5270.
[Abstract] [Full Text] [PDF]

N. Mori, R. Suzuki, T. Furuno, D. M. McKay, M. Wada, R. Teshima, J. Bienenstock, and M. Nakanishi
Nerve-mast cell (RBL) interaction: RBL membrane ruffling occurs at the contact site with an activated neurite
Am J Physiol Cell Physiol, December 1, 2002; 283(6): C1738 - C1744.
[Abstract] [Full Text] [PDF]

G. O. C. Cory, R. Garg, R. Cramer, and A. J. Ridley
Phosphorylation of Tyrosine 291 Enhances the Ability of WASp to Stimulate Actin Polymerization and Filopodium Formation
J. Biol. Chem., November 15, 2002; 277(47): 45115 - 45121.
[Abstract] [Full Text] [PDF]

C. Y. Cheng and D. D. Mruk
Cell Junction Dynamics in the Testis: Sertoli-Germ Cell Interactions and Male Contraceptive Development
Physiol Rev, October 1, 2002; 82(4): 825 - 874.
[Abstract] [Full Text] [PDF]

P. Maderna, D. C. Cottell, G. Berlasconi, N. A. Petasis, H. R. Brady, and C. Godson
Lipoxins Induce Actin Reorganization in Monocytes and Macrophages But Not in Neutrophils : Differential Involvement of Rho GTPases
Am. J. Pathol., June 1, 2002; 160(6): 2275 - 2283.
[Abstract] [Full Text] [PDF]

S. Carreno, E. Caron, C. Cougoule, L. J. Emorine, and I. Maridonneau-Parini
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J. Biol. Chem., May 31, 2002; 277(23): 21007 - 21016.
[Abstract] [Full Text] [PDF]

H. Kanazawa, K. Ohsawa, Y. Sasaki, S. Kohsaka, and Y. Imai
Macrophage/Microglia-specific Protein Iba1 Enhances Membrane Ruffling and Rac Activation via Phospholipase C-gamma -dependent Pathway
J. Biol. Chem., May 24, 2002; 277(22): 20026 - 20032.
[Abstract] [Full Text] [PDF]

N. Harden, M. Ricos, K. Yee, J. Sanny, C. Langmann, H. Yu, W. Chia, and L. Lim
Drac1 and Crumbs participate in amnioserosa morphogenesis during dorsal closure in Drosophila
J. Cell Sci., May 15, 2002; 115(10): 2119 - 2129.
[Abstract] [Full Text] [PDF]

J. Sturge, J. Hamelin, and G. E. Jones
N-WASP activation by a {beta}1-integrin-dependent mechanism supports PI3K-independent chemotaxis stimulated by urokinase-type plasminogen activator
J. Cell Sci., February 15, 2002; 115(4): 699 - 711.
[Abstract] [Full Text] [PDF]

K. A. Beningo and Y.-l. Wang
Fc-receptor-mediated phagocytosis is regulated by mechanical properties of the target
J. Cell Sci., February 15, 2002; 115(4): 849 - 856.
[Abstract] [Full Text] [PDF]

J. A. Ronald, C. V. Ionescu, K. A. Rogers, and M. Sandig
Differential regulation of transendothelial migration of THP-1 cells by ICAM-1/LFA-1 and VCAM-1/VLA-4
J. Leukoc. Biol., October 1, 2001; 70(4): 601 - 609.
[Abstract] [Full Text] [PDF]

C V Clevenger and J B Kline
Prolactin receptor signal transduction
Lupus, October 1, 2001; 10(10): 706 - 718.
[Abstract] [PDF]

H. Yu, D. Leitenberg, B. Li, and R. A. Flavell
Deficiency of Small Gtpase Rac2 Affects T Cell Activation
J. Exp. Med., October 1, 2001; 194(7): 915 - 926.
[Abstract] [Full Text] [PDF]

M. Kobayashi, E. Azuma, M. Ido, M. Hirayama, Q. Jiang, S. Iwamoto, T. Kumamoto, H. Yamamoto, M. Sakurai, and Y. Komada
A Pivotal Role of Rho GTPase in the Regulation of Morphology and Function of Dendritic Cells
J. Immunol., October 1, 2001; 167(7): 3585 - 3591.
[Abstract] [Full Text] [PDF]

D. KIM, S. KIM, H. KOH, S.-O. YOON, A.-S. CHUNG, K. S. CHO, and J. CHUNG
Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production
FASEB J, September 1, 2001; 15(11): 1953 - 1962.
[Abstract] [Full Text] [PDF]

S. Burns, A. J. Thrasher, M. P. Blundell, L. Machesky, and G. E. Jones
Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation
Blood, August 15, 2001; 98(4): 1142 - 1149.
[Abstract] [Full Text] [PDF]

K. M. Giles, K. Ross, A. G. Rossi, N. A. Hotchin, C. Haslett, and I. Dransfield
Glucocorticoid Augmentation of Macrophage Capacity for Phagocytosis of Apoptotic Cells Is Associated with Reduced p130Cas Expression, Loss of Paxillin/pyk2 Phosphorylation, and High Levels of Active Rac
J. Immunol., July 15, 2001; 167(2): 976 - 986.
[Abstract] [Full Text] [PDF]

R. A. Worthylake, S. Lemoine, J. M. Watson, and K. Burridge
RhoA is required for monocyte tail retraction during transendothelial migration
J. Cell Biol., July 9, 2001; 154(1): 147 - 160.
[Abstract] [Full Text] [PDF]

J. B. Kline, D. J. Moore, and C. V. Clevenger
Activation and Association of the Tec Tyrosine Kinase with the Human Prolactin Receptor: Mapping of a Tec/Vav1-Receptor Binding Site
Mol. Endocrinol., May 1, 2001; 15(5): 832 - 841.
[Abstract] [Full Text]

F. J. Pixley, P. S. W. Lee, J. S. Condeelis, and E. R. Stanley
Protein Tyrosine Phosphatase {phi} Regulates Paxillin Tyrosine Phosphorylation and Mediates Colony-Stimulating Factor 1-Induced Morphological Changes in Macrophages
Mol. Cell. Biol., March 1, 2001; 21(5): 1795 - 1809.
[Abstract] [Full Text]

A. J. Ridley
Rho GTPases and cell migration
J. Cell Sci., January 8, 2001; 114(15): 2713 - 2722.
[Abstract] [Full Text] [PDF]

D. Davy, H. Campbell, S Fountain, D de Jong, and M. Crouch
The flightless I protein colocalizes with actin- and microtubule-based structures in motile Swiss 3T3 fibroblasts: evidence for the involvement of PI 3-kinase and Ras-related small GTPases
J. Cell Sci., January 2, 2001; 114(3): 549 - 562.
[Abstract] [PDF]

G. E. Jones
Cellular signaling in macrophage migration and chemotaxis
J. Leukoc. Biol., November 1, 2000; 68(5): 593 - 602.
[Abstract] [Full Text]

S. Yayoshi-Yamamoto, I. Taniuchi, and T. Watanabe
FRL, a Novel Formin-Related Protein, Binds to Rac and Regulates Cell Motility and Survival of Macrophages
Mol. Cell. Biol., September 15, 2000; 20(18): 6872 - 6881.
[Abstract] [Full Text]

T. Kawashima, K. Hirose, T. Satoh, A. Kaneko, Y. Ikeda, Y. Kaziro, T. Nosaka, and T. Kitamura
MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells
Blood, September 15, 2000; 96(6): 2116 - 2124.
[Abstract] [Full Text] [PDF]

D. A. Williams, W. Tao, F. Yang, C. Kim, Y. Gu, P. Mansfield, J. E. Levine, B. Petryniak, C. W. Derrow, C. Harris, et al.
Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency
Blood, September 1, 2000; 96(5): 1646 - 1654.
[Abstract] [Full Text] [PDF]

H. Yoshida, Y. Tomiyama, J. Ishikawa, K. Oritani, I. Matsumura, M. Shiraga, T. Yokota, Y. Okajima, M. Ogawa, J.-i. Miyagawa, et al.
Integrin-associated protein/CD47 regulates motile activity in human B-cell lines through CDC42
Blood, July 1, 2000; 96(1): 234 - 241.
[Abstract] [Full Text] [PDF]

H. E. Matheny, T. L. Deem, and J. M. Cook-Mills
Lymphocyte Migration Through Monolayers of Endothelial Cell Lines Involves VCAM-1 Signaling Via Endothelial Cell NADPH Oxidase
J. Immunol., June 15, 2000; 164(12): 6550 - 6559.
[Abstract] [Full Text] [PDF]

I. Royal, N. Lamarche-Vane, L. Lamorte, K. Kaibuchi, and M. Park
Activation of Cdc42, Rac, PAK, and Rho-Kinase in Response to Hepatocyte Growth Factor Differentially Regulates Epithelial Cell Colony Spreading and Dissociation
Mol. Biol. Cell, May 1, 2000; 11(5): 1709 - 1725.
[Abstract] [Full Text]

L. Tian, D. L. Nelson, and D. M. Stewart
Cdc42-interacting Protein 4 Mediates Binding of the Wiskott-Aldrich Syndrome Protein to Microtubules
J. Biol. Chem., March 10, 2000; 275(11): 7854 - 7861.
[Abstract] [Full Text] [PDF]

A. Philips, P. Roux, V. Coulon, J.-M. Bellanger, A. Vie, M.-L. Vignais, and J. M. Blanchard
Differential Effect of Rac and Cdc42 on p38 Kinase Activity and Cell Cycle Progression of Nonadherent Primary Mouse Fibroblasts
J. Biol. Chem., February 25, 2000; 275(8): 5911 - 5917.
[Abstract] [Full Text] [PDF]

L. M. Williams and A. J. Ridley
Lipopolysaccharide Induces Actin Reorganization and Tyrosine Phosphorylation of Pyk2 and Paxillin in Monocytes and Macrophages
J. Immunol., February 15, 2000; 164(4): 2028 - 2036.
[Abstract] [Full Text] [PDF]

K. Hill, S. Welti, J. Yu, J. T. Murray, S.-C. Yip, J. S. Condeelis, J. E. Segall, and J. M. Backer
Specific Requirement for the p85-p110alpha Phosphatidylinositol 3-Kinase during Epidermal Growth Factor-stimulated Actin Nucleation in Breast Cancer Cells
J. Biol. Chem., February 11, 2000; 275(6): 3741 - 3744.
[Abstract] [Full Text] [PDF]

X. Ren, W. Kiosses, D. Sieg, C. Otey, D. Schlaepfer, and M. Schwartz
Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover
J. Cell Sci., January 10, 2000; 113(20): 3673 - 3678.
[Abstract] [PDF]

F Castellano, P Montcourrier, and P Chavrier
Membrane recruitment of Rac1 triggers phagocytosis
J. Cell Sci., January 9, 2000; 113(17): 2955 - 2961.
[Abstract] [PDF]

K Ohsawa, Y Imai, H Kanazawa, Y Sasaki, and S Kohsaka
Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia
J. Cell Sci., January 9, 2000; 113(17): 3073 - 3084.
[Abstract] [PDF]

N Araki, T Hatae, T Yamada, and S Hirohashi
Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages: analysis by fluorescence ratio imaging
J. Cell Sci., January 9, 2000; 113(18): 3329 - 3340.
[Abstract] [PDF]

D. J. Lee, D. Cox, J. Li, and S. Greenberg
Rac1 and Cdc42 Are Required for Phagocytosis, but Not NF-kappa B-dependent Gene Expression, in Macrophages Challenged with Pseudomonas aeruginosa
J. Biol. Chem., January 7, 2000; 275(1): 141 - 146.
[Abstract] [Full Text] [PDF]

S Ory, Y Munari-Silem, P Fort, and P Jurdic
Rho and Rac exert antagonistic functions on spreading of macrophage-derived multinucleated cells and are not required for actin fiber formation
J. Cell Sci., January 4, 2000; 113(7): 1177 - 1188.
[Abstract] [PDF]

T. Sumi, K. Matsumoto, Y. Takai, and T. Nakamura
Cofilin Phosphorylation and Actin Cytoskeletal Dynamics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2
J. Cell Biol., December 27, 1999; 147(7): 1519 - 1532.
[Abstract] [Full Text] [PDF]

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