The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Nothwehr, S. F.
	Articles by Hindes, A. E.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Nothwehr, S. F.
	Articles by Hindes, A. E.

Ammerer, G., Hunter, C. P., Rothman, J. H., Saari, G. C., Valls, L. A. and Stevens, T. H (1986). PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors. Mol. Cell. Biol 6, 2490-2499.[Abstract/Free Full Text]

Bankaitis, V. A., Johnson, L. M. and Emr, S. D (1986). Isolation of yeast mutants defective in protein targeting to the vacuole. Proc. Nat. Acad. Sci. USA 83, 9075-9079.[Abstract/Free Full Text]

Banta, L. M., Robinson, J. S., Klionsky, D. J. and Emr, S. D (1988). Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. J. Cell Biol 107, 1369-1383.[Abstract/Free Full Text]

Cereghino, J. L., Marcusson, E. G. and Emr, S. D (1995). The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization. Mol. Biol. Cell 6, 1089-1102.[Abstract]

Cooper, A. A. and Stevens, T. H (1996). Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J. Cell Biol 133, 529-541.[Abstract/Free Full Text]

Cunningham, K. W. and Wickner, W. T (1989). Yeast KEX2 protease and mannosyltransferase I are localized to distinct compartments of the secretory pathway. Yeast 5, 25-33.[Medline]

Davis, N. G., Horecka, J. L. and Sprague, G. F. Jr (1993). Cis -and trans -acting functions required for endocytosis of the yeast pheromone receptors. J. Cell Biol 122, 53-65.[Abstract/Free Full Text]

Ekena, K. and Stevens, T. H (1995). The SaccharomycescerevisiaeMVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol. Cell. Biol 15, 1671-1678.[Abstract]

Franzusoff, A. and Schekman, R (1989). Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation. EMBO J 8, 2695-2702.[Medline]

Fuller, R. S., Sterne, R. E. and Thorner, J (1988). Enzymes required for yeast prohormone processing. Annu. Rev. Physiol 50, 345-362.[Medline]

Graham, T. R. and Emr, S. D (1991). Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant. J. Cell Biol 114, 207-218.[Abstract/Free Full Text]

Hill, K. J. and Stevens, T. H (1994). Vma21p is a yeast membrane protein retained in the endoplasmic reticulum by a di-lysine motif and is required for the assembly of the vacuolar H(+)-ATPase complex. Mol. Biol. Cell 5, 1039-1050.[Abstract]

Jones, E. W (1977). Proteinase mutants of Saccharomycescerevisiae. Genetics 85, 23-33.[Abstract/Free Full Text]

K\232hrer, K. and Emr, S. D (1993). The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases. J. Biol. Chem 268, 559-569.[Abstract/Free Full Text]

Kornfeld, S. and Mellman, I (1989). The biogenesis of lysosomes. Annu. Rev. Cell Biol 5, 483-525.

Kurten, R. C., Cadena, D. L. and Gill, G. N (1996). Enhanced degradation of EGF receptors by a sorting nexin, Snx1. Science 272, 1008-1010.[Abstract]

Manolson, M. F., Proteau, D., Preston, R. A., Stenbit, A., Roberts, B. T., Hoyt, M. A., Preuss, D., et al (1992). The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase. J. Biol. Chem 267, 14294-14303.[Abstract/Free Full Text]

Marcusson, E. G., Horazdovsky, B. F., Cereghino, J. L., Gharakhanian, E. and Emr, S. D (1994). The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell 77, 579-586.[Medline]

Nothwehr, S. F., Roberts, C. J. and Stevens, T. H (1993). Membrane protein retention in the yeast Golgi apparatus: dipeptidyl aminopeptidase A is retained by a cytoplasmic signal containing aromatic residues. J. Cell Biol 121, 1197-1209.[Abstract/Free Full Text]

Nothwehr, S. F. and Stevens, T. H (1994). Sorting of membrane proteins in the yeast secretory pathway. J. Biol. Chem 269, 10185-10188.[Free Full Text]

Nothwehr, S. F., Conibear, E. and Stevens, T. H (1995). Golgi and vacuolar membrane proteins reach the vacuole in vps1 mutant yeast cells via the plasma membrane. J. Cell Biol 129, 35-46.[Abstract/Free Full Text]

Nothwehr, S. F., Bryant, N. J. and Stevens, T. H (1996). The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol. Cell. Biol 16, 2700-2707.[Abstract]

Novick, P., Osmond, B. C. and Botstein, D (1989). Suppressors of yeast actin mutations. Genetics 121, 659-674.[Abstract/Free Full Text]

Piper, R. C., Cooper, A. A., Yang, H. and Stevens, T. H (1995). VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J. Cell Biol 3, 603-617.

Raths, S., Rohrer, J., Crausaz, F. and Riezman, H (1993). end3 and end4 : two mutants defective in receptor-mediated and fluid phase endocytosis in Saccharomyces cerevisiae. J. Cell Biol 120, 55-65.[Abstract/Free Full Text]

Raymond, C. K., Howald-Stevenson, I., Vater, C. A. and Stevens, T. H (1992). Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol. Biol. Cell 3, 1389-1402.[Abstract]

Raymond, C. K., Roberts, C. J., Moore, K. E., Howald, I. and Stevens, T. H (1992). Biogenesis of the vacuole in Saccharomyces cerevisiae. Int. Rev. Cytol 139, 59-120.[Medline]

Redding, K., Holcomb, C. and Fuller, R. S (1991). Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomycescerevisiae. J. Cell Biol 113, 527-538.[Abstract/Free Full Text]

Rieder, S. E., Banta, L. M., Kohrer, K., McCaffery, J. M. and Emr, S. D (1996). Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol. Biol. Cell 7, 985-999.[Abstract]

Roberts, C. J., Raymond, C. K., Yamashiro, C. T. and Stevens, T. H (1991). Methods for studying the yeast vacuole. Meth. Enzymol 194, 644-661.[Medline]

Roberts, C. J., Nothwehr, S. F. and Stevens, T. H (1992). Membrane protein sorting in the yeast secretory pathway: evidence that the vacuole may be the default compartment. J. Cell Biol 119, 69-83.[Abstract/Free Full Text]

Robinson, J. S., Klionsky, D. J., Banta, L. M. and Emr, S. D (1988). Protein sorting in Saccharomyces cerevisiae : isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol. Cell. Biol 8, 4936-4948.[Abstract/Free Full Text]

Rose, M. D., Novick, P., Thomas, J. H., Botstein, D. and Fink, G. R (1987). A Saccharomycescerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60, 237-243.[Medline]

Rothman, J. H. and Stevens, T. H (1986). Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell 47, 1041-1051.[Medline]

Sanger, F., Nicklen, S. and Coulson, A. R (1977). DNA sequencing with chain termination inhibitors. Proc. Nat. Acad. Sci. USA 74, 5463-5467.[Abstract/Free Full Text]

Schimm\232ller, F. and Riezman, H (1993). Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast. J. Cell Sci 106, 823-830.[Abstract]

Singer, B. and Riezman, H (1990). Detection of an intermediate compartment involved in transport of-factor from the plasma membrane to the vacuole in yeast. J. Cell Biol 110, 1911-1922.[Abstract/Free Full Text]

Sorger, P. K. and Pelham, H. R. B (1988). Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phoshorylation. Cell 54, 855-864.[Medline]

Stevens, T., Esmon, B. and Schekman, R (1982). Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell 30, 439-448.[Medline]

Tyers, M., Tokiwa, G. and Futcher, B (1993). Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins. EMBO J 12, 1955-1968.[Medline]

Vater, C. A., Raymond, C. K., Ekena, K., Howald, S. I. and Stevens, T. H (1992). The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomycescerevisiae , is a GTPase with two functionally separable domains. J. Cell Biol 119, 773-786.[Abstract/Free Full Text]

Vida, T. A., Huyer, G. and Emr, S. D (1993). Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment. J. Cell Biol 121, 1245-1256.[Abstract/Free Full Text]

Wilcox, C. A., Redding, K., Wright, R. and Fuller, R. S (1992). Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole. Mol. Biol. Cell 3, 1353-1371.[Abstract]

Wilsbach, K. and Payne, G. S (1993). Vps1p, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiae. EMBO J 12, 3049-3059.[Medline]

This article has been cited by other articles:

T. I. Strochlic, T. G. Setty, A. Sitaram, and C. G. Burd
Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling
J. Cell Biol., April 9, 2007; 177(1): 115 - 125.
[Abstract] [Full Text] [PDF]

R. Rojas, S. Kametaka, C. R. Haft, and J. S. Bonifacino
Interchangeable but Essential Functions of SNX1 and SNX2 in the Association of Retromer with Endosomes and the Trafficking of Mannose 6-Phosphate Receptors
Mol. Cell. Biol., February 1, 2007; 27(3): 1112 - 1124.
[Abstract] [Full Text] [PDF]

T. Iwaki, A. Hosomi, S. Tokudomi, Y. Kusunoki, Y. Fujita, Y. Giga-Hama, N. Tanaka, and K. Takegawa
Vacuolar protein sorting receptor in Schizosaccharomyces pombe.
Microbiology, May 1, 2006; 152(Pt 5): 1523 - 1532.
[Abstract] [Full Text] [PDF]

A. Gullapalli, B. L. Wolfe, C. T. Griffin, T. Magnuson, and J. Trejo
An Essential Role for SNX1 in Lysosomal Sorting of Protease-activated Receptor-1: Evidence for Retromer-, Hrs-, and Tsg101-independent Functions of Sorting Nexins
Mol. Biol. Cell, March 1, 2006; 17(3): 1228 - 1238.
[Abstract] [Full Text] [PDF]

J. G. Carlton, M. V. Bujny, B. J. Peter, V. M. J. Oorschot, A. Rutherford, R. S. Arkell, J. Klumperman, H. T. McMahon, and P. J. Cullen
Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport
J. Cell Sci., October 1, 2005; 118(19): 4527 - 4539.
[Abstract] [Full Text] [PDF]

D. Wang, M. Guo, Z. Liang, J. Fan, Z. Zhu, J. Zang, Z. Zhu, X. Li, M. Teng, L. Niu, et al.
Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-like Fold and Two Protein-Protein Interaction Sites
J. Biol. Chem., June 17, 2005; 280(24): 22962 - 22967.
[Abstract] [Full Text] [PDF]

P. Bruinsma, R. G. Spelbrink, and S. F. Nothwehr
Retrograde Transport of the Mannosyltransferase Och1p to the Early Golgi Requires a Component of the COG Transport Complex
J. Biol. Chem., September 17, 2004; 279(38): 39814 - 39823.
[Abstract] [Full Text] [PDF]

J. H. Choi, W.-P. Hong, M. J. Kim, J. H. Kim, S. H. Ryu, and P.-G. Suh
Sorting nexin 16 regulates EGF receptor trafficking by phosphatidylinositol-3-phosphate interaction with the Phox domain
J. Cell Sci., August 15, 2004; 117(18): 4209 - 4218.
[Abstract] [Full Text] [PDF]

M. G. Roth
Phosphoinositides in Constitutive Membrane Traffic
Physiol Rev, July 1, 2004; 84(3): 699 - 730.
[Abstract] [Full Text] [PDF]

T. Koga, M. Onishi, Y. Nakamura, A. Hirata, T. Nakamura, C. Shimoda, T. Iwaki, K. Takegawa, and Y. Fukui
Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe
Genes Cells, June 1, 2004; 9(6): 561 - 574.
[Abstract] [Full Text] [PDF]

A. Gullapalli, T. A. Garrett, M. M. Paing, C. T. Griffin, Y. Yang, and J. Trejo
A Role for Sorting Nexin 2 in Epidermal Growth Factor Receptor Down-regulation: Evidence for Distinct Functions of Sorting Nexin 1 and 2 in Protein Trafficking
Mol. Biol. Cell, May 1, 2004; 15(5): 2143 - 2155.
[Abstract] [Full Text] [PDF]

M. Kato and W. Wickner
Vam10p defines a Sec18p-independent step of priming that allows yeast vacuole tethering
PNAS, May 27, 2003; 100(11): 6398 - 6403.
[Abstract] [Full Text] [PDF]

P. Burda, S. M. Padilla, S. Sarkar, and S. D. Emr
Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase
J. Cell Sci., October 15, 2002; 115(20): 3889 - 3900.
[Abstract] [Full Text] [PDF]

D. G. Schwarz, C. T. Griffin, E. A. Schneider, D. Yee, and T. Magnuson
Genetic Analysis of Sorting Nexins 1 and 2 Reveals a Redundant and Essential Function in Mice
Mol. Biol. Cell, October 1, 2002; 13(10): 3588 - 3600.
[Abstract] [Full Text] [PDF]

M. N.J. Seaman and H. P. Williams
Identification of the Functional Domains of Yeast Sorting Nexins Vps5p and Vps17p
Mol. Biol. Cell, August 1, 2002; 13(8): 2826 - 2840.
[Abstract] [Full Text] [PDF]

Y. Wang, Y. Zhou, K. Szabo, C. R. Haft, and J. Trejo
Down-Regulation of Protease-activated Receptor-1 Is Regulated by Sorting Nexin 1
Mol. Biol. Cell, June 1, 2002; 13(6): 1965 - 1976.
[Abstract] [Full Text] [PDF]

J. W. Yu and M. A. Lemmon
All Phox Homology (PX) Domains from Saccharomyces cerevisiae Specifically Recognize Phosphatidylinositol 3-Phosphate
J. Biol. Chem., November 16, 2001; 276(47): 44179 - 44184.
[Abstract] [Full Text] [PDF]

S.-A. Ha, J. T. Bunch, H. Hama, D. B. DeWald, and S. F. Nothwehr
A Novel Mechanism for Localizing Membrane Proteins to Yeast Trans-Golgi Network Requires Function of Synaptojanin-like Protein
Mol. Biol. Cell, October 1, 2001; 12(10): 3175 - 3190.
[Abstract] [Full Text] [PDF]

J. Xu, D. Liu, G. Gill, and Z. Songyang
Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides
J. Cell Biol., August 20, 2001; 154(4): 699 - 706.
[Abstract] [Full Text] [PDF]

G. Borrelly, J.-C. Boyer, B. Touraine, W. Szponarski, M. Rambier, and R. Gibrat
The yeast mutant vps5Delta affected in the recycling of Golgi membrane proteins displays an enhanced vacuolar Mg2+/H+ exchange activity
PNAS, August 1, 2001; (2001) 161215198.
[Abstract] [Full Text] [PDF]

R. Kurten, A. Eddington, P Chowdhury, R. Smith, A. Davidson, and B. Shank
Self-assembly and binding of a sorting nexin to sorting endosomes
J. Cell Sci., January 5, 2001; 114(9): 1743 - 1756.
[Abstract] [PDF]

E. S. Bensen, B. G. Yeung, and G. S. Payne
Ric1p and the Ypt6p GTPase Function in a Common Pathway Required for Localization of Trans-Golgi Network Membrane Proteins
Mol. Biol. Cell, January 1, 2001; 12(1): 13 - 26.
[Abstract] [Full Text]

C. R. Haft, M. d. l. L. Sierra, R. Bafford, M. A. Lesniak, V. A. Barr, and S. I. Taylor
Human Orthologs of Yeast Vacuolar Protein Sorting Proteins Vps26, 29, and 35: Assembly into Multimeric Complexes
Mol. Biol. Cell, December 1, 2000; 11(12): 4105 - 4116.
[Abstract] [Full Text]

S. F. Nothwehr, S.-A. Ha, and P. Bruinsma
Sorting of Yeast Membrane Proteins into an Endosome-to-Golgi Pathway Involves Direct Interaction of Their Cytosolic Domains with Vps35p
J. Cell Biol., October 18, 2000; 151(2): 297 - 310.
[Abstract] [Full Text] [PDF]

E. Conibear and T. H. Stevens
Vps52p, Vps53p, and Vps54p Form a Novel Multisubunit Complex Required for Protein Sorting at the Yeast Late Golgi
Mol. Biol. Cell, January 1, 2000; 11(1): 305 - 323.
[Abstract] [Full Text]

R. G. Spelbrink and S. F. Nothwehr
The Yeast GRD20 Gene Is Required for Protein Sorting in the trans-Golgi Network/Endosomal System and for Polarization of the Actin Cytoskeleton
Mol. Biol. Cell, December 1, 1999; 10(12): 4263 - 4281.
[Abstract] [Full Text]

S. F. Nothwehr, P. Bruinsma, and L. A. Strawn
Distinct Domains within Vps35p Mediate the Retrieval of Two Different Cargo Proteins from the Yeast Prevacuolar/Endosomal Compartment
Mol. Biol. Cell, April 1, 1999; 10(4): 875 - 890.
[Abstract] [Full Text]

C. R. Haft, M. de la Luz Sierra, V. A. Barr, D. H. Haft, and S. I. Taylor
Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors
Mol. Cell. Biol., December 1, 1998; 18(12): 7278 - 7287.
[Abstract] [Full Text]

M. N.J. Seaman, J. Michael McCaffery, and S. D. Emr
A Membrane Coat Complex Essential for Endosome-to-Golgi Retrograde Transport in Yeast
J. Cell Biol., August 10, 1998; 142(3): 665 - 681.
[Abstract] [Full Text] [PDF]

W. Voos and T. H. Stevens
Retrieval of Resident Late-Golgi Membrane Proteins from the Prevacuolar Compartment of Saccharomyces cerevisiae Is Dependent on the Function of Grd19p
J. Cell Biol., February 9, 1998; 140(3): 577 - 590.
[Abstract] [Full Text] [PDF]

L.-S. Chin, M. C. Raynor, X. Wei, H.-Q. Chen, and L. Li
Hrs Interacts with Sorting Nexin 1 and Regulates Degradation of Epidermal Growth Factor Receptor
J. Biol. Chem., March 2, 2001; 276(10): 7069 - 7078.
[Abstract] [Full Text] [PDF]

S. A. Phillips, V. A. Barr, D. H. Haft, S. I. Taylor, and C. R. Haft
Identification and Characterization of SNX15, a Novel Sorting Nexin Involved in Protein Trafficking
J. Biol. Chem., February 9, 2001; 276(7): 5074 - 5084.
[Abstract] [Full Text] [PDF]

G. Borrelly, J.-C. Boyer, B. Touraine, W. Szponarski, M. Rambier, and R. Gibrat
The yeast mutant vps5Delta affected in the recycling of Golgi membrane proteins displays an enhanced vacuolar Mg2+/H+ exchange activity
PNAS, August 14, 2001; 98(17): 9660 - 9665.
[Abstract] [Full Text] [PDF]

P. P. Poon, S. F. Nothwehr, R. A. Singer, and G. C. Johnston
The Gcs1 and Age2 ArfGAP proteins provide overlapping essential function for transport from the yeast trans-Golgi network
J. Cell Biol., December 24, 2001; 155(7): 1239 - 1250.
[Abstract] [Full Text] [PDF]

S. M. Jones, S. K. Foreman, B. B. Shank, and R. C. Kurten
EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain
Am J Physiol Cell Physiol, March 1, 2002; 282(3): C420 - C433.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Nothwehr, S. F.

Articles by Hindes, A. E.

Search for Related Content

PubMed

PubMed Citation

Articles by Nothwehr, S. F.

Articles by Hindes, A. E.

				R. Rojas, S. Kametaka, C. R. Haft, and J. S. Bonifacino Interchangeable but Essential Functions of SNX1 and SNX2 in the Association of Retromer with Endosomes and the Trafficking of Mannose 6-Phosphate Receptors Mol. Cell. Biol., February 1, 2007; 27(3): 1112 - 1124. [Abstract] [Full Text] [PDF]

				T. Iwaki, A. Hosomi, S. Tokudomi, Y. Kusunoki, Y. Fujita, Y. Giga-Hama, N. Tanaka, and K. Takegawa Vacuolar protein sorting receptor in Schizosaccharomyces pombe. Microbiology, May 1, 2006; 152(Pt 5): 1523 - 1532. [Abstract] [Full Text] [PDF]

				A. Gullapalli, B. L. Wolfe, C. T. Griffin, T. Magnuson, and J. Trejo An Essential Role for SNX1 in Lysosomal Sorting of Protease-activated Receptor-1: Evidence for Retromer-, Hrs-, and Tsg101-independent Functions of Sorting Nexins Mol. Biol. Cell, March 1, 2006; 17(3): 1228 - 1238. [Abstract] [Full Text] [PDF]

				J. G. Carlton, M. V. Bujny, B. J. Peter, V. M. J. Oorschot, A. Rutherford, R. S. Arkell, J. Klumperman, H. T. McMahon, and P. J. Cullen Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport J. Cell Sci., October 1, 2005; 118(19): 4527 - 4539. [Abstract] [Full Text] [PDF]

				D. Wang, M. Guo, Z. Liang, J. Fan, Z. Zhu, J. Zang, Z. Zhu, X. Li, M. Teng, L. Niu, et al. Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-like Fold and Two Protein-Protein Interaction Sites J. Biol. Chem., June 17, 2005; 280(24): 22962 - 22967. [Abstract] [Full Text] [PDF]

				P. Bruinsma, R. G. Spelbrink, and S. F. Nothwehr Retrograde Transport of the Mannosyltransferase Och1p to the Early Golgi Requires a Component of the COG Transport Complex J. Biol. Chem., September 17, 2004; 279(38): 39814 - 39823. [Abstract] [Full Text] [PDF]

				J. H. Choi, W.-P. Hong, M. J. Kim, J. H. Kim, S. H. Ryu, and P.-G. Suh Sorting nexin 16 regulates EGF receptor trafficking by phosphatidylinositol-3-phosphate interaction with the Phox domain J. Cell Sci., August 15, 2004; 117(18): 4209 - 4218. [Abstract] [Full Text] [PDF]

				M. G. Roth Phosphoinositides in Constitutive Membrane Traffic Physiol Rev, July 1, 2004; 84(3): 699 - 730. [Abstract] [Full Text] [PDF]

				T. Koga, M. Onishi, Y. Nakamura, A. Hirata, T. Nakamura, C. Shimoda, T. Iwaki, K. Takegawa, and Y. Fukui Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe Genes Cells, June 1, 2004; 9(6): 561 - 574. [Abstract] [Full Text] [PDF]

				A. Gullapalli, T. A. Garrett, M. M. Paing, C. T. Griffin, Y. Yang, and J. Trejo A Role for Sorting Nexin 2 in Epidermal Growth Factor Receptor Down-regulation: Evidence for Distinct Functions of Sorting Nexin 1 and 2 in Protein Trafficking Mol. Biol. Cell, May 1, 2004; 15(5): 2143 - 2155. [Abstract] [Full Text] [PDF]

				M. Kato and W. Wickner Vam10p defines a Sec18p-independent step of priming that allows yeast vacuole tethering PNAS, May 27, 2003; 100(11): 6398 - 6403. [Abstract] [Full Text] [PDF]

				P. Burda, S. M. Padilla, S. Sarkar, and S. D. Emr Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase J. Cell Sci., October 15, 2002; 115(20): 3889 - 3900. [Abstract] [Full Text] [PDF]

				D. G. Schwarz, C. T. Griffin, E. A. Schneider, D. Yee, and T. Magnuson Genetic Analysis of Sorting Nexins 1 and 2 Reveals a Redundant and Essential Function in Mice Mol. Biol. Cell, October 1, 2002; 13(10): 3588 - 3600. [Abstract] [Full Text] [PDF]

				M. N.J. Seaman and H. P. Williams Identification of the Functional Domains of Yeast Sorting Nexins Vps5p and Vps17p Mol. Biol. Cell, August 1, 2002; 13(8): 2826 - 2840. [Abstract] [Full Text] [PDF]

				Y. Wang, Y. Zhou, K. Szabo, C. R. Haft, and J. Trejo Down-Regulation of Protease-activated Receptor-1 Is Regulated by Sorting Nexin 1 Mol. Biol. Cell, June 1, 2002; 13(6): 1965 - 1976. [Abstract] [Full Text] [PDF]

				J. W. Yu and M. A. Lemmon All Phox Homology (PX) Domains from Saccharomyces cerevisiae Specifically Recognize Phosphatidylinositol 3-Phosphate J. Biol. Chem., November 16, 2001; 276(47): 44179 - 44184. [Abstract] [Full Text] [PDF]

				S.-A. Ha, J. T. Bunch, H. Hama, D. B. DeWald, and S. F. Nothwehr A Novel Mechanism for Localizing Membrane Proteins to Yeast Trans-Golgi Network Requires Function of Synaptojanin-like Protein Mol. Biol. Cell, October 1, 2001; 12(10): 3175 - 3190. [Abstract] [Full Text] [PDF]

				J. Xu, D. Liu, G. Gill, and Z. Songyang Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides J. Cell Biol., August 20, 2001; 154(4): 699 - 706. [Abstract] [Full Text] [PDF]

				G. Borrelly, J.-C. Boyer, B. Touraine, W. Szponarski, M. Rambier, and R. Gibrat The yeast mutant vps5Delta affected in the recycling of Golgi membrane proteins displays an enhanced vacuolar Mg2+/H+ exchange activity PNAS, August 1, 2001; (2001) 161215198. [Abstract] [Full Text] [PDF]

				R. Kurten, A. Eddington, P Chowdhury, R. Smith, A. Davidson, and B. Shank Self-assembly and binding of a sorting nexin to sorting endosomes J. Cell Sci., January 5, 2001; 114(9): 1743 - 1756. [Abstract] [PDF]

				E. S. Bensen, B. G. Yeung, and G. S. Payne Ric1p and the Ypt6p GTPase Function in a Common Pathway Required for Localization of Trans-Golgi Network Membrane Proteins Mol. Biol. Cell, January 1, 2001; 12(1): 13 - 26. [Abstract] [Full Text]

				C. R. Haft, M. d. l. L. Sierra, R. Bafford, M. A. Lesniak, V. A. Barr, and S. I. Taylor Human Orthologs of Yeast Vacuolar Protein Sorting Proteins Vps26, 29, and 35: Assembly into Multimeric Complexes Mol. Biol. Cell, December 1, 2000; 11(12): 4105 - 4116. [Abstract] [Full Text]

				S. F. Nothwehr, S.-A. Ha, and P. Bruinsma Sorting of Yeast Membrane Proteins into an Endosome-to-Golgi Pathway Involves Direct Interaction of Their Cytosolic Domains with Vps35p J. Cell Biol., October 18, 2000; 151(2): 297 - 310. [Abstract] [Full Text] [PDF]

				E. Conibear and T. H. Stevens Vps52p, Vps53p, and Vps54p Form a Novel Multisubunit Complex Required for Protein Sorting at the Yeast Late Golgi Mol. Biol. Cell, January 1, 2000; 11(1): 305 - 323. [Abstract] [Full Text]

				R. G. Spelbrink and S. F. Nothwehr The Yeast GRD20 Gene Is Required for Protein Sorting in the trans-Golgi Network/Endosomal System and for Polarization of the Actin Cytoskeleton Mol. Biol. Cell, December 1, 1999; 10(12): 4263 - 4281. [Abstract] [Full Text]

				S. F. Nothwehr, P. Bruinsma, and L. A. Strawn Distinct Domains within Vps35p Mediate the Retrieval of Two Different Cargo Proteins from the Yeast Prevacuolar/Endosomal Compartment Mol. Biol. Cell, April 1, 1999; 10(4): 875 - 890. [Abstract] [Full Text]

				C. R. Haft, M. de la Luz Sierra, V. A. Barr, D. H. Haft, and S. I. Taylor Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors Mol. Cell. Biol., December 1, 1998; 18(12): 7278 - 7287. [Abstract] [Full Text]

				M. N.J. Seaman, J. Michael McCaffery, and S. D. Emr A Membrane Coat Complex Essential for Endosome-to-Golgi Retrograde Transport in Yeast J. Cell Biol., August 10, 1998; 142(3): 665 - 681. [Abstract] [Full Text] [PDF]

				W. Voos and T. H. Stevens Retrieval of Resident Late-Golgi Membrane Proteins from the Prevacuolar Compartment of Saccharomyces cerevisiae Is Dependent on the Function of Grd19p J. Cell Biol., February 9, 1998; 140(3): 577 - 590. [Abstract] [Full Text] [PDF]

				L.-S. Chin, M. C. Raynor, X. Wei, H.-Q. Chen, and L. Li Hrs Interacts with Sorting Nexin 1 and Regulates Degradation of Epidermal Growth Factor Receptor J. Biol. Chem., March 2, 2001; 276(10): 7069 - 7078. [Abstract] [Full Text] [PDF]