Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1

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Normal Arp2/3 complex activation in platelets lacking WASp
Blood, August 28, 2002; 100(6): 2113 - 2122.
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V. Vouret-Craviari, C. Bourcier, E. Boulter, and E. Van Obberghen-Schilling
Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells
J. Cell Sci., June 15, 2002; 115(12): 2475 - 2484.
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Y. Liu, J. C. Loijens, K. H. Martin, A. V. Karginov, and J. T. Parsons
The Association of ASAP1, an ADP Ribosylation Factor-GTPase Activating Protein, with Focal Adhesion Kinase Contributes to the Process of Focal Adhesion Assembly
Mol. Biol. Cell, June 1, 2002; 13(6): 2147 - 2156.
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K. G. Birukov, A. A. Birukova, S. M. Dudek, A. D. Verin, M. T. Crow, X. Zhan, N. DePaola, and J. G. N. Garcia
Shear Stress-Mediated Cytoskeletal Remodeling and Cortactin Translocation in Pulmonary Endothelial Cells
Am. J. Respir. Cell Mol. Biol., April 1, 2002; 26(4): 453 - 464.
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M. Hagel, E. L. George, A. Kim, R. Tamimi, S. L. Opitz, C. E. Turner, A. Imamoto, and S. M. Thomas
The Adaptor Protein Paxillin Is Essential for Normal Development in the Mouse and Is a Critical Transducer of Fibronectin Signaling
Mol. Cell. Biol., February 1, 2002; 22(3): 901 - 915.
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S. A. Weed, A. V. Karginov, D. A. Schafer, A. M. Weaver, A. W. Kinley, J. A. Cooper, and J. T. Parsons
Cortactin Localization to Sites of Actin Assembly in Lamellipodia Requires Interactions with F-Actin and the Arp2/3 Complex
J. Cell Biol., September 25, 2000; 151(1): 29 - 40.
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J. N. Lavoie, C. Champagne, M.-C. Gingras, and A. Robert
Adenovirus E4 Open Reading Frame 4-induced Apoptosis Involves Dysregulation of Src Family Kinases
J. Cell Biol., September 5, 2000; 150(5): 1037 - 1056.
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A. R. Gallagher, A. Cedzich, N. Gretz, S. Somlo, and R. Witzgall
The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton
PNAS, April 11, 2000; 97(8): 4017 - 4022.
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Y Cheng, S Leung, and D Mangoura
Transient suppression of cortactin ectopically induces large telencephalic neurons towards a GABAergic phenotype
J. Cell Sci., January 9, 2000; 113(18): 3161 - 3172.
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M Sheng and E Kim
The Shank family of scaffold proteins
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M. M. Kessels, A. E. Y. Engqvist-Goldstein, and D. G. Drubin
Association of Mouse Actin-binding Protein 1 (mAbp1/SH3P7), an Src Kinase Target, with Dynamic Regions of the Cortical Actin Cytoskeleton in Response to Rac1 Activation
Mol. Biol. Cell, January 1, 2000; 11(1): 393 - 412.
[Abstract] [Full Text]

M. P. Quinlan and J. L. Hyatt
Establishment of the Circumferential Actin Filament Network Is a Prerequisite for Localization of the Cadherin-Catenin Complex in Epithelial Cells
Cell Growth Differ., December 1, 1999; 10(12): 839 - 854.
[Abstract] [Full Text]

D. H. Campbell, R. L. Sutherland, and R. J. Daly
Signaling Pathways and Structural Domains Required for Phosphorylation of EMS1/Cortactin
Cancer Res., October 1, 1999; 59(20): 5376 - 5385.
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M. W. Rochlin, M. E. Dailey, and P. C. Bridgman
Polymerizing Microtubules Activate Site-directed F-Actin Assembly in Nerve Growth Cones
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[Abstract] [Full Text]

A. Kapus, K. Szaszi, J. Sun, S. Rizoli, and O. D. Rotstein
Cell Shrinkage Regulates Src Kinases and Induces Tyrosine Phosphorylation of Cortactin, Independent of the Osmotic Regulation of Na+/H+ Exchangers
J. Biol. Chem., March 19, 1999; 274(12): 8093 - 8102.
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				L. I. Cosen-Binker and A. Kapus Cortactin: The Gray Eminence of the Cytoskeleton. Physiology, October 1, 2006; 21(5): 352 - 361. [Abstract] [Full Text] [PDF]

				J. R. Jacobson, S. M. Dudek, P. A. Singleton, I. A. Kolosova, A. D. Verin, and J. G. N. Garcia Endothelial cell barrier enhancement by ATP is mediated by the small GTPase Rac and cortactin. Am J Physiol Lung Cell Mol Physiol, August 1, 2006; 291(2): L289 - L295. [Abstract] [Full Text] [PDF]

				L. Boyer, A. Doye, M. Rolando, G. Flatau, P. Munro, P. Gounon, R. Clement, C. Pulcini, M. R. Popoff, A. Mettouchi, et al. Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors J. Cell Biol., June 5, 2006; 173(5): 809 - 819. [Abstract] [Full Text] [PDF]

				T. Y. E. Sayegh, P. D. Arora, L. Fan, C. A. Laschinger, P. A. Greer, C. A. McCulloch, and A. Kapus Phosphorylation of N-Cadherin-associated Cortactin by Fer Kinase Regulates N-Cadherin Mobility and Intercellular Adhesion Strength Mol. Biol. Cell, December 1, 2005; 16(12): 5514 - 5527. [Abstract] [Full Text] [PDF]

				B. A. Webb, R. Eves, S. W. Crawley, S. Zhou, G. P. Cote, and A. S. Mak PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner Am J Physiol Cell Physiol, October 1, 2005; 289(4): C898 - C907. [Abstract] [Full Text] [PDF]

				M. Lambotin, I. Hoffmann, M.-P. Laran-Chich, X. Nassif, P. O. Couraud, and S. Bourdoulous Invasion of endothelial cells by Neisseria meningitidis requires cortactin recruitment by a phosphoinositide-3-kinase/Rac1 signalling pathway triggered by the lipo-oligosaccharide J. Cell Sci., August 15, 2005; 118(16): 3805 - 3816. [Abstract] [Full Text] [PDF]

				R. W. Tilghman, J. K. Slack-Davis, N. Sergina, K. H. Martin, M. Iwanicki, E. D. Hershey, H. E. Beggs, L. F. Reichardt, and J. T. Parsons Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells J. Cell Sci., June 15, 2005; 118(12): 2613 - 2623. [Abstract] [Full Text] [PDF]

				Y. Liu, G. M. Yerushalmi, P. R. Grigera, and J. T. Parsons Mislocalization or Reduced Expression of Arf GTPase-activating Protein ASAP1 Inhibits Cell Spreading and Migration by Influencing Arf1 GTPase Cycling J. Biol. Chem., March 11, 2005; 280(10): 8884 - 8892. [Abstract] [Full Text] [PDF]

				D. Shan, L. Chen, J. T. Njardarson, C. Gaul, X. Ma, S. J. Danishefsky, and X.-Y. Huang Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice PNAS, March 8, 2005; 102(10): 3772 - 3776. [Abstract] [Full Text] [PDF]

				N. Sauvonnet, A. Dujeancourt, and A. Dautry-Varsat Cortactin and dynamin are required for the clathrin-independent endocytosis of {gamma}c cytokine receptor J. Cell Biol., January 3, 2005; 168(1): 155 - 163. [Abstract] [Full Text] [PDF]

				J. R. Kowalski, C. Egile, S. Gil, S. B. Snapper, R. Li, and S. M. Thomas Cortactin regulates cell migration through activation of N-WASP J. Cell Sci., January 1, 2005; 118(1): 79 - 87. [Abstract] [Full Text] [PDF]

				V. Radhika, D. Onesime, J. H. Ha, and N. Dhanasekaran G{alpha}13 Stimulates Cell Migration through Cortactin-interacting Protein Hax-1 J. Biol. Chem., November 19, 2004; 279(47): 49406 - 49413. [Abstract] [Full Text] [PDF]

				L. Bougneres, S. E. Girardin, S. A. Weed, A. V. Karginov, J.-C. Olivo-Marin, J. T. Parsons, P. J. Sansonetti, and G. T. Van Nhieu Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells J. Cell Biol., July 19, 2004; 166(2): 225 - 235. [Abstract] [Full Text] [PDF]

				B. Knoll and U. Drescher Src Family Kinases Are Involved in EphA Receptor-Mediated Retinal Axon Guidance J. Neurosci., July 14, 2004; 24(28): 6248 - 6257. [Abstract] [Full Text] [PDF]

				N. Martinez-Quiles, H.-Y. H. Ho, M. W. Kirschner, N. Ramesh, and R. S. Geha Erk/Src Phosphorylation of Cortactin Acts as a Switch On-Switch Off Mechanism That Controls Its Ability To Activate N-WASP Mol. Cell. Biol., June 15, 2004; 24(12): 5269 - 5280. [Abstract] [Full Text] [PDF]

				S. M. Dudek, J. R. Jacobson, E. T. Chiang, K. G. Birukov, P. Wang, X. Zhan, and J. G. N. Garcia Pulmonary Endothelial Cell Barrier Enhancement by Sphingosine 1-Phosphate: ROLES FOR CORTACTIN AND MYOSIN LIGHT CHAIN KINASE J. Biol. Chem., June 4, 2004; 279(23): 24692 - 24700. [Abstract] [Full Text] [PDF]

				B. L. Lua and B. C. Low BPGAP1 Interacts with Cortactin and Facilitates Its Translocation to Cell Periphery for Enhanced Cell Migration Mol. Biol. Cell, June 1, 2004; 15(6): 2873 - 2883. [Abstract] [Full Text] [PDF]

				J. R. Jacobson, S. M. Dudek, K. G. Birukov, S. Q. Ye, D. N. Grigoryev, R. E. Girgis, and J. G. N. Garcia Cytoskeletal Activation and Altered Gene Expression in Endothelial Barrier Regulation by Simvastatin Am. J. Respir. Cell Mol. Biol., May 1, 2004; 30(5): 662 - 670. [Abstract] [Full Text] [PDF]

				F. M. Helwani, E. M. Kovacs, A. D. Paterson, S. Verma, R. G. Ali, A. S. Fanning, S. A. Weed, and A. S. Yap Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization J. Cell Biol., March 15, 2004; 164(6): 899 - 910. [Abstract] [Full Text] [PDF]

				H. Hering and M. Sheng Activity-Dependent Redistribution and Essential Role of Cortactin in Dendritic Spine Morphogenesis J. Neurosci., December 17, 2003; 23(37): 11759 - 11769. [Abstract] [Full Text] [PDF]

				A. G. S. H. van Rossum, J. H. de Graaf, E. Schuuring-Scholtes, P. M. Kluin, Y.-x. Fan, X. Zhan, W. H. Moolenaar, and E. Schuuring Alternative Splicing of the Actin Binding Domain of Human Cortactin Affects Cell Migration J. Biol. Chem., November 14, 2003; 278(46): 45672 - 45679. [Abstract] [Full Text] [PDF]

				K. L. Barkalow, H. Falet, J. E. Italiano Jr., A. van Vugt, C. L. Carpenter, A. D. Schreiber, and J. H. Hartwig Role for phosphoinositide 3-kinase in Fc{gamma}RIIA-induced platelet shape change Am J Physiol Cell Physiol, October 1, 2003; 285(4): C797 - C805. [Abstract] [Full Text] [PDF]

				P. Hou, L. Estrada, A. W. Kinley, J. T. Parsons, A. B. Vojtek, and J. L. Gorski Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape Hum. Mol. Genet., August 15, 2003; 12(16): 1981 - 1993. [Abstract] [Full Text] [PDF]

				J. A. Head, D. Jiang, M. Li, L. J. Zorn, E. M. Schaefer, J. T. Parsons, and S. A. Weed Cortactin Tyrosine Phosphorylation Requires Rac1 Activity and Association with the Cortical Actin Cytoskeleton Mol. Biol. Cell, August 1, 2003; 14(8): 3216 - 3229. [Abstract] [Full Text] [PDF]

				J. K. Slack-Davis, S. T. Eblen, M. Zecevic, S. A. Boerner, A. Tarcsafalvi, H. B. Diaz, M. S. Marshall, M. J. Weber, J. T. Parsons, and A. D. Catling PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation J. Cell Biol., July 21, 2003; 162(2): 281 - 291. [Abstract] [Full Text] [PDF]

				T. Uruno, J. Liu, Y. Li, N. Smith, and X. Zhan Sequential Interaction of Actin-related Proteins 2 and 3 (Arp2/3) Complex with Neural Wiscott-Aldrich Syndrome Protein (N-WASP) and Cortactin during Branched Actin Filament Network Formation J. Biol. Chem., July 3, 2003; 278(28): 26086 - 26093. [Abstract] [Full Text] [PDF]

				A. D. Rogat and K. G. Miller A role for myosin VI in actin dynamics at sites of membrane remodeling during Drosophila spermatogenesis J. Cell Sci., March 14, 2003; 115(24): 4855 - 4865. [Abstract] [Full Text] [PDF]

				E. W. Krueger, J. D. Orth, H. Cao, and M. A. McNiven A Dynamin-Cortactin-Arp2/3 Complex Mediates Actin Reorganization in Growth Factor-stimulated Cells Mol. Biol. Cell, March 1, 2003; 14(3): 1085 - 1096. [Abstract] [Full Text] [PDF]

				E. C. Struckhoff and E. A. Lundquist The actin-binding protein UNC-115 is an effector of Rac signaling during axon pathfinding in C. elegans Development, February 15, 2003; 130(4): 693 - 704. [Abstract] [Full Text] [PDF]

				C. Vidal, B. Geny, J. Melle, M. Jandrot-Perrus, and M. Fontenay-Roupie Cdc42/Rac1-dependent activation of the p21-activated kinase (PAK) regulates human platelet lamellipodia spreading: implication of the cortical-actin binding protein cortactin Blood, December 15, 2002; 100(13): 4462 - 4469. [Abstract] [Full Text] [PDF]