The cdc25B phosphatase is essential for the G2/M phase transition in human cells

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				S. Varmeh and J. J. Manfredi Inappropriate Activation of Cyclin-dependent Kinases by the Phosphatase Cdc25b Results in Premature Mitotic Entry and Triggers a p53-dependent Checkpoint J. Biol. Chem., April 3, 2009; 284(14): 9475 - 9488. [Abstract] [Full Text] [PDF]

				S. Shreeram, W. K. Hee, and D. V. Bulavin Cdc25A Serine 123 Phosphorylation Couples Centrosome Duplication with DNA Replication and Regulates Tumorigenesis Mol. Cell. Biol., December 15, 2008; 28(24): 7442 - 7450. [Abstract] [Full Text] [PDF]

				C. Feng, A. Yu, Y. Liu, J. Zhang, Z. Zong, W. Su, Z. Zhang, D. Yu, Q.-Y. Sun, and B. Yu Involvement of Protein Kinase B/AKT in Early Development of Mouse Fertilized Eggs Biol Reprod, September 1, 2007; 77(3): 560 - 568. [Abstract] [Full Text] [PDF]

				S. Varmeh-Ziaie and J. J. Manfredi The Dual Specificity Phosphatase Cdc25B, but Not the Closely Related Cdc25C, Is Capable of Inhibiting Cellular Proliferation in a Manner Dependent upon Its Catalytic Activity J. Biol. Chem., August 24, 2007; 282(34): 24633 - 24641. [Abstract] [Full Text] [PDF]

				A. Sturrock, T. P. Huecksteadt, K. Norman, K. Sanders, T. M. Murphy, P. Chitano, K. Wilson, J. R. Hoidal, and T. P. Kennedy Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells Am J Physiol Lung Cell Mol Physiol, June 1, 2007; 292(6): L1543 - L1555. [Abstract] [Full Text] [PDF]

				E. Schmitt, R. Boutros, C. Froment, B. Monsarrat, B. Ducommun, and C. Dozier CHK1 phosphorylates CDC25B during the cell cycle in the absence of DNA damage J. Cell Sci., October 15, 2006; 119(20): 4269 - 4275. [Abstract] [Full Text] [PDF]

				E. Gershon, D. Galiani, and N. Dekel Cytoplasmic polyadenylation controls cdc25B mRNA translation in rat oocytes resuming meiosis Reproduction, July 1, 2006; 132(1): 21 - 31. [Abstract] [Full Text] [PDF]

				H Nakabayashi, M Hara, and K Shimizu Prognostic significance of CDC25B expression in gliomas. J. Clin. Pathol., July 1, 2006; 59(7): 725 - 728. [Abstract] [Full Text] [PDF]

				Q. Liu and J. V. Ruderman Aurora A, mitotic entry, and spindle bipolarity PNAS, April 11, 2006; 103(15): 5811 - 5816. [Abstract] [Full Text] [PDF]

				S. Uchida, A. Kubo, R. Kizu, H. Nakagama, T. Matsunaga, Y. Ishizaka, and K. Yamashita Amino Acids C-Terminal to the 14-3-3 Binding Motif in CDC25B Affect the Efficiency of 14-3-3 Binding. J. Biochem., April 1, 2006; 139(4): 761 - 769. [Abstract] [Full Text] [PDF]

				J. S. Stanford and J. V. Ruderman Changes in Regulatory Phosphorylation of Cdc25C Ser287 and Wee1 Ser549 during Normal Cell Cycle Progression and Checkpoint Arrests Mol. Biol. Cell, December 1, 2005; 16(12): 5749 - 5760. [Abstract] [Full Text] [PDF]

				A. Lindqvist, H. Kallstrom, A. Lundgren, E. Barsoum, and C. K. Rosenthal Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome J. Cell Biol., October 10, 2005; 171(1): 35 - 45. [Abstract] [Full Text] [PDF]

				G. Brady, L. Boggan, A. Bowie, and L. A. J. O'Neill Schlafen-1 Causes a Cell Cycle Arrest by Inhibiting Induction of Cyclin D1 J. Biol. Chem., September 2, 2005; 280(35): 30723 - 30734. [Abstract] [Full Text] [PDF]

				Y. Hirose, M. Katayama, O. K. Mirzoeva, M. S. Berger, and R. O. Pieper Akt Activation Suppresses Chk2-Mediated, Methylating Agent-Induced G2 Arrest and Protects from Temozolomide-Induced Mitotic Catastrophe and Cellular Senescence Cancer Res., June 1, 2005; 65(11): 4861 - 4869. [Abstract] [Full Text] [PDF]

				Y. Kanemori, K. Uto, and N. Sagata {beta}-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases PNAS, May 3, 2005; 102(18): 6279 - 6284. [Abstract] [Full Text] [PDF]

				A. M. Ferguson, L. S. White, P. J. Donovan, and H. Piwnica-Worms Normal Cell Cycle and Checkpoint Responses in Mice and Cells Lacking Cdc25B and Cdc25C Protein Phosphatases Mol. Cell. Biol., April 1, 2005; 25(7): 2853 - 2860. [Abstract] [Full Text] [PDF]

				A. Lindqvist, H. Kallstrom, and C. Karlsson Rosenthal Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress J. Cell Sci., October 1, 2004; 117(21): 4979 - 4990. [Abstract] [Full Text] [PDF]

				S. Uchida, A. Kuma, M. Ohtsubo, M. Shimura, M. Hirata, H. Nakagama, T. Matsunaga, Y. Ishizaka, and K. Yamashita Binding of 14-3-3{beta} but not 14-3-3{sigma} controls the cytoplasmic localization of CDC25B: binding site preferences of 14-3-3 subtypes and the subcellular localization of CDC25B J. Cell Sci., June 15, 2004; 117(14): 3011 - 3020. [Abstract] [Full Text] [PDF]

				S. Dutertre, M. Cazales, M. Quaranta, C. Froment, V. Trabut, C. Dozier, G. Mirey, J.-P. Bouche, N. Theis-Febvre, E. Schmitt, et al. Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition J. Cell Sci., May 15, 2004; 117(12): 2523 - 2531. [Abstract] [Full Text] [PDF]

				Y. Han, H. Shen, B. I. Carr, P. Wipf, J. S. Lazo, and S.-s. Pan NAD(P)H:Quinone Oxidoreductase-1-Dependent and -Independent Cytotoxicity of Potent Quinone Cdc25 Phosphatase Inhibitors J. Pharmacol. Exp. Ther., April 1, 2004; 309(1): 64 - 70. [Abstract] [Full Text]

				V. Sanchez, A. K. McElroy, and D. H. Spector Mechanisms Governing Maintenance of Cdk1/Cyclin B1 Kinase Activity in Cells Infected with Human Cytomegalovirus J. Virol., December 15, 2003; 77(24): 13214 - 13224. [Abstract] [Full Text] [PDF]

				W. Wu, B. M. Slomovitz, J. Celestino, L. Chung, A. Thornton, and K. H. Lu Coordinate Expression of Cdc25B and ER-{alpha} Is Frequent in Low-Grade Endometrioid Endometrial Carcinoma but Uncommon in High-Grade Endometrioid and Nonendometrioid Carcinomas Cancer Res., October 1, 2003; 63(19): 6195 - 6199. [Abstract] [Full Text] [PDF]

				N. Giles, A. Forrest, and B. Gabrielli 14-3-3 Acts as an Intramolecular Bridge to Regulate cdc25B Localization and Activity J. Biol. Chem., August 1, 2003; 278(31): 28580 - 28587. [Abstract] [Full Text] [PDF]

				P. Turowski, C. Franckhauser, M. C. Morris, P. Vaglio, A. Fernandez, and N. J. C. Lamb Functional cdc25C Dual-Specificity Phosphatase Is Required for S-Phase Entry in Human Cells Mol. Biol. Cell, July 1, 2003; 14(7): 2984 - 2998. [Abstract] [Full Text] [PDF]

				Z. Xiao, Z. Chen, A. H. Gunasekera, T. J. Sowin, S. H. Rosenberg, S. Fesik, and H. Zhang Chk1 Mediates S and G2 Arrests through Cdc25A Degradation in Response to DNA-damaging Agents J. Biol. Chem., June 6, 2003; 278(24): 21767 - 21773. [Abstract] [Full Text] [PDF]

				D. Li, J. Zhu, P. F. Firozi, J. L. Abbruzzese, D. B. Evans, K. Cleary, H. Friess, and S. Sen Overexpression of Oncogenic STK15/BTAK/Aurora A Kinase in Human Pancreatic Cancer Clin. Cancer Res., March 1, 2003; 9(3): 991 - 997. [Abstract] [Full Text] [PDF]

				X. Wang, H. Kiyokawa, M. B. Dennewitz, and R. H. Costa The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration PNAS, December 24, 2002; 99(26): 16881 - 16886. [Abstract] [Full Text] [PDF]

				E. Okubo, J. M. Lehman, and T. D. Friedrich Negative Regulation of Mitotic Promoting Factor by the Checkpoint Kinase Chk1 in Simian Virus 40 Lytic Infection J. Virol., December 20, 2002; 77(2): 1257 - 1267. [Abstract] [Full Text] [PDF]

				L. Pu, A. A. Amoscato, M. E. Bier, and J. S. Lazo Dual G1 and G2 Phase Inhibition by a Novel, Selective Cdc25 Inhibitor 7-Chloro-6-(2-morpholin-4-ylethylamino)- quinoline-5,8-dione J. Biol. Chem., November 27, 2002; 277(49): 46877 - 46885. [Abstract] [Full Text] [PDF]

				V. Baldin, K. Pelpel, M. Cazales, C. Cans, and B. Ducommun Nuclear Localization of CDC25B1 and Serine 146 Integrity Are Required for Induction of Mitosis J. Biol. Chem., September 13, 2002; 277(38): 35176 - 35182. [Abstract] [Full Text] [PDF]