The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form

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J. Longin, P. Guillaumot, M.-A. Chauvin, A.-M. Morera, and B. Le Magueresse-Battistoni
MT1-MMP in rat testicular development and the control of Sertoli cell proMMP-2 activation
J. Cell Sci., January 6, 2001; 114(11): 2125 - 2134.
[Abstract] [Full Text] [PDF]

J. MARTIN, L. EYNSTONE, M. DAVIES, and R. STEADMAN
Induction of Metalloproteinases by Glomerular Mesangial Cells Stimulated by Proteins of the Extracellular Matrix
J. Am. Soc. Nephrol., January 1, 2001; 12(1): 88 - 96.
[Abstract] [Full Text]

I. Kazes, I. Elalamy, J.-D. Sraer, M. Hatmi, and G. Nguyen
Platelet release of trimolecular complex components MT1-MMP/TIMP2/MMP2: involvement in MMP2 activation and platelet aggregation
Blood, November 1, 2000; 96(9): 3064 - 3069.
[Abstract] [Full Text] [PDF]

A. Béliveau, M. Bérubé, A. Rousseau, G. Pelletier, and S. L. Guérin
Expression of Integrin {alpha}5{beta}1 and MMPs Associated with Epithelioid Morphology and Malignancy of Uveal Melanoma
Invest. Ophthalmol. Vis. Sci., July 1, 2000; 41(8): 2363 - 2372.
[Abstract] [Full Text]

I. Yana and S. J. Weiss
Regulation of Membrane Type-1 Matrix Metalloproteinase Activation by Proprotein Convertases
Mol. Biol. Cell, July 1, 2000; 11(7): 2387 - 2401.
[Abstract] [Full Text]

W. R. English, X. S. Puente, J. M. P. Freije, V. Knauper, A. Amour, A. Merryweather, C. Lopez-Otin, and G. Murphy
Membrane Type 4 Matrix Metalloproteinase (MMP17) Has Tumor Necrosis Factor-alpha Convertase Activity but Does Not Activate Pro-MMP2
J. Biol. Chem., May 5, 2000; 275(19): 14046 - 14055.
[Abstract] [Full Text] [PDF]

S. Hernandez-Barrantes, M. Toth, M. M. Bernardo, M. Yurkova, D. C. Gervasi, Y. Raz, Q. A. Sang, and R. Fridman
Binding of Active (57 kDa) Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) to Tissue Inhibitor of Metalloproteinase (TIMP)-2 Regulates MT1-MMP Processing and Pro-MMP-2 Activation
J. Biol. Chem., April 14, 2000; 275(16): 12080 - 12089.
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N. Koshikawa, G. Giannelli, V. Cirulli, K. Miyazaki, and V. Quaranta
Role of Cell Surface Metalloprotease MT1-MMP in Epithelial Cell Migration over Laminin-5
J. Cell Biol., February 7, 2000; 148(3): 615 - 624.
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L Yan, M. Moses, S Huang, and D. Ingber
Adhesion-dependent control of matrix metalloproteinase-2 activation in human capillary endothelial cells
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J. Esparza, C. Vilardell, J. Calvo, M. Juan, J. Vives, A. Urbano-Marquez, J. Yague, and M. C. Cid
Fibronectin Upregulates Gelatinase B (MMP-9) and Induces Coordinated Expression of Gelatinase A (MMP-2) and Its Activator MT1-MMP (MMP-14) by Human T Lymphocyte Cell Lines. A Process Repressed Through RAS/MAP Kinase Signaling Pathways
Blood, October 15, 1999; 94(8): 2754 - 2766.
[Abstract] [Full Text] [PDF]

T. Sugiura and F. Berditchevski
Function of {alpha}3{beta}1�Tetraspanin Protein Complexes in Tumor Cell Invasion. Evidence for the Role of the Complexes in Production of Matrix Metalloproteinase 2 (MMP-2)
J. Cell Biol., September 20, 1999; 146(6): 1375 - 1389.
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S. M. Ellerbroek, D. A. Fishman, A. S. Kearns, L. M. Bafetti, and M. S. Stack
Ovarian Carcinoma Regulation of Matrix Metalloproteinase-2 and Membrane Type 1 Matrix Metalloproteinase through {beta}1 Integrin
Cancer Res., April 1, 1999; 59(7): 1635 - 1641.
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Z. Wang, R. Juttermann, and P. D. Soloway
TIMP-2 Is Required for Efficient Activation of proMMP-2 in Vivo
J. Biol. Chem., August 18, 2000; 275(34): 26411 - 26415.
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C. M. Overall, E. Tam, G. A. McQuibban, C. Morrison, U. M. Wallon, H. F. Bigg, A. E. King, and C. R. Roberts
Domain Interactions in the Gelatinase A{middle dot}TIMP-2{middle dot}MT1-MMP Activation Complex. THE ECTODOMAIN OF THE 44-kDa FORM OF MEMBRANE TYPE-1 MATRIX METALLOPROTEINASE DOES NOT MODULATE GELATINASE A ACTIVATION
J. Biol. Chem., December 8, 2000; 275(50): 39497 - 39506.
[Abstract] [Full Text] [PDF]

M. Toth, M. M. Bernardo, D. C. Gervasi, P. D. Soloway, Z. Wang, H. F. Bigg, C. M. Overall, Y. A. DeClerck, H. Tschesche, M. L. Cher, et al.
Tissue Inhibitor of Metalloproteinase (TIMP)-2 Acts Synergistically with Synthetic Matrix Metalloproteinase (MMP) Inhibitors but Not with TIMP-4 to Enhance the (Membrane Type 1)-MMP-dependent Activation of Pro-MMP-2
J. Biol. Chem., December 22, 2000; 275(52): 41415 - 41423.
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D. V. Rozanov, E. I. Deryugina, B. I. Ratnikov, E. Z. Monosov, G. N. Marchenko, J. P. Quigley, and A. Y. Strongin
Mutation Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP). THE ROLE OF THE CYTOPLASMIC TAIL CYS574, THE ACTIVE SITE GLU240, AND FURIN CLEAVAGE MOTIFS IN OLIGOMERIZATION, PROCESSING, AND SELF-PROTEOLYSIS OF MT1-MMP EXPRESSED IN BREAST CARCINOMA CELLS
J. Biol. Chem., July 6, 2001; 276(28): 25705 - 25714.
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A. M. Belkin, S. S. Akimov, L. S. Zaritskaya, B. I. Ratnikov, E. I. Deryugina, and A. Y. Strongin
Matrix-dependent Proteolysis of Surface Transglutaminase by Membrane-type Metalloproteinase Regulates Cancer Cell Adhesion and Locomotion
J. Biol. Chem., May 18, 2001; 276(21): 18415 - 18422.
[Abstract] [Full Text] [PDF]

Y. Zhuge and J. Xu
Rac1 Mediates Type I Collagen-dependent MMP-2 Activation. ROLE IN CELL INVASION ACROSS COLLAGEN BARRIER
J. Biol. Chem., May 4, 2001; 276(19): 16248 - 16256.
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M. Pavlaki, J. Cao, M. Hymowitz, W.-T. Chen, W. Bahou, and S. Zucker
A Conserved Sequence within the Propeptide Domain of Membrane Type 1 Matrix Metalloproteinase Is Critical for Function as an Intramolecular Chaperone

				Y. Itoh, N. Ito, H. Nagase, and M. Seiki The Second Dimer Interface of MT1-MMP, the Transmembrane Domain, Is Essential for ProMMP-2 Activation on the Cell Surface J. Biol. Chem., May 9, 2008; 283(19): 13053 - 13062. [Abstract] [Full Text] [PDF]

				S. D. Sithu, W. R. English, P. Olson, D. Krubasik, A. H. Baker, G. Murphy, and S. E. D'Souza Membrane-type 1-Matrix Metalloproteinase Regulates Intracellular Adhesion Molecule-1 (ICAM-1)-mediated Monocyte Transmigration J. Biol. Chem., August 24, 2007; 282(34): 25010 - 25019. [Abstract] [Full Text] [PDF]

				T.-V. Do, J. C. Symowicz, D. M. Berman, L. A. Liotta, E. F. Petricoin III, M. S. Stack, and D. A. Fishman Lysophosphatidic Acid Down-Regulates Stress Fibers and Up-Regulates Pro-Matrix Metalloproteinase-2 Activation in Ovarian Cancer Cells Mol. Cancer Res., February 1, 2007; 5(2): 121 - 131. [Abstract] [Full Text] [PDF]

				D. M. Browe and C. M. Baumgarten EGFR Kinase Regulates Volume-sensitive Chloride Current Elicited by Integrin Stretch via PI-3K and NADPH Oxidase in Ventricular Myocytes J. Gen. Physiol., February 27, 2006; 127(3): 237 - 251. [Abstract] [Full Text] [PDF]

				P. C. Lunter, J. W.J. van Kilsdonk, H. van Beek, I. M.H.A. Cornelissen, M. Bergers, P. H.G.M. Willems, G. N.P. van Muijen, and G. W.M. Swart Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166/MEMD), a Novel Actor in Invasive Growth, Controls Matrix Metalloproteinase Activity Cancer Res., October 1, 2005; 65(19): 8801 - 8808. [Abstract] [Full Text] [PDF]

				R. T. Schermuly, H. Yilmaz, H. A. Ghofrani, K. Woyda, S. Pullamsetti, A. Schulz, T. Gessler, R. Dumitrascu, N. Weissmann, F. Grimminger, et al. Inhaled Iloprost Reverses Vascular Remodeling in Chronic Experimental Pulmonary Hypertension Am. J. Respir. Crit. Care Med., August 1, 2005; 172(3): 358 - 363. [Abstract] [Full Text] [PDF]

				P. Osenkowski, S. O. Meroueh, D. Pavel, S. Mobashery, and R. Fridman Mutational and Structural Analyses of the Hinge Region of Membrane Type 1-Matrix Metalloproteinase and Enzyme Processing J. Biol. Chem., July 15, 2005; 280(28): 26160 - 26168. [Abstract] [Full Text] [PDF]

				H. Lepetit, S. Eddahibi, E. Fadel, E. Frisdal, C. Munaut, A. Noel, M. Humbert, S. Adnot, M-P. D'Ortho, and C. Lafuma Smooth muscle cell matrix metalloproteinases in idiopathic pulmonary arterial hypertension Eur. Respir. J., May 1, 2005; 25(5): 834 - 842. [Abstract] [Full Text] [PDF]

				C. F. Albright, N. Graciani, W. Han, E. Yue, R. Stein, Z. Lai, M. Diamond, R. Dowling, L. Grimminger, S.-Y. Zhang, et al. Matrix metalloproteinase-activated doxorubicin prodrugs inhibit HT1080 xenograft growth better than doxorubicin with less toxicity Mol. Cancer Ther., May 1, 2005; 4(5): 751 - 760. [Abstract] [Full Text] [PDF]

				H. G. Munshi, Y. I. Wu, S. Mukhopadhyay, A. J. Ottaviano, A. Sassano, J. E. Koblinski, L. C. Platanias, and M. S. Stack Differential Regulation of Membrane Type 1-Matrix Metalloproteinase Activity by ERK 1/2- and p38 MAPK-modulated Tissue Inhibitor of Metalloproteinases 2 Expression Controls Transforming Growth Factor-{beta}1-induced Pericellular Collagenolysis J. Biol. Chem., September 10, 2004; 279(37): 39042 - 39050. [Abstract] [Full Text] [PDF]

				R. T. Schermuly, K. P. Kreisselmeier, H. A. Ghofrani, A. Samidurai, S. Pullamsetti, N. Weissmann, C. Schudt, L. Ermert, W. Seeger, and F. Grimminger Antiremodeling Effects of Iloprost and the Dual-Selective Phosphodiesterase 3/4 Inhibitor Tolafentrine in Chronic Experimental Pulmonary Hypertension Circ. Res., April 30, 2004; 94(8): 1101 - 1108. [Abstract] [Full Text] [PDF]

				M. K.Y. Siu and C. Y. Cheng Interactions of Proteases, Protease Inhibitors, and the {beta}1 Integrin/Laminin {gamma}3 Protein Complex in the Regulation of Ectoplasmic Specialization Dynamics in the Rat Testis Biol Reprod, April 1, 2004; 70(4): 945 - 964. [Abstract] [Full Text] [PDF]

				H. Zhao, M. M. Bernardo, P. Osenkowski, A. Sohail, D. Pei, H. Nagase, M. Kashiwagi, P. D. Soloway, Y. A. DeClerck, and R. Fridman Differential Inhibition of Membrane Type 3 (MT3)-Matrix Metalloproteinase (MMP) and MT1-MMP by Tissue Inhibitor of Metalloproteinase (TIMP)-2 and TIMP-3 Regulates Pro-MMP-2 Activation J. Biol. Chem., March 5, 2004; 279(10): 8592 - 8601. [Abstract] [Full Text] [PDF]

				R. Boland, B. J. Joyce, M. J. Wallace, H. Stanton, A. J. Fosang, R. A. Pierce, R. Harding, and S. B. Hooper Cortisol enhances structural maturation of the hypoplastic fetal lung in sheep J. Physiol., January 15, 2004; 554(2): 505 - 517. [Abstract] [Full Text] [PDF]

				A. Remacle, G. Murphy, and C. Roghi Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface J. Cell Sci., October 1, 2003; 116(19): 3905 - 3916. [Abstract] [Full Text] [PDF]

				D. V. Rozanov and A. Y. Strongin Membrane Type-1 Matrix Metalloproteinase Functions as a Proprotein Self-convertase. EXPRESSION OF THE LATENT ZYMOGEN IN PICHIA PASTORIS, AUTOLYTIC ACTIVATION, AND THE PEPTIDE SEQUENCE OF THE CLEAVAGE FORMS J. Biol. Chem., February 28, 2003; 278(10): 8257 - 8260. [Abstract] [Full Text] [PDF]

				B. G. Galvez, S. Matias-Roman, M. Yanez-Mo, F. Sanchez-Madrid, and A. G. Arroyo ECM regulates MT1-MMP localization with {beta}1 or {alpha}v{beta}3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells J. Cell Biol., November 7, 2002; 159(3): 509 - 521. [Abstract] [Full Text] [PDF]

				H. G. Munshi, Y. I. Wu, E. V. Ariztia, and M. S. Stack Calcium Regulation of Matrix Metalloproteinase-mediated Migration in Oral Squamous Cell Carcinoma Cells J. Biol. Chem., October 25, 2002; 277(44): 41480 - 41488. [Abstract] [Full Text] [PDF]

				E. M. Tam, Y. I. Wu, G. S. Butler, M. S. Stack, and C. M. Overall Collagen Binding Properties of the Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Hemopexin C Domain. THE ECTODOMAIN OF THE 44-kDa AUTOCATALYTIC PRODUCT OF MT1-MMP INHIBITS CELL INVASION BY DISRUPTING NATIVE TYPE I COLLAGEN CLEAVAGE J. Biol. Chem., October 4, 2002; 277(41): 39005 - 39014. [Abstract] [Full Text] [PDF]

				O. Buchman-Shaked, Z. Kraiem, Y. Gonen, and S. Goldman Presence of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinase in Human Sperm J Androl, September 1, 2002; 23(5): 702 - 708. [Abstract] [Full Text] [PDF]

				J. E. Koblinski, J. Dosescu, M. Sameni, K. Moin, K. Clark, and B. F. Sloane Interaction of Human Breast Fibroblasts with Collagen I Increases Secretion of Procathepsin B J. Biol. Chem., August 23, 2002; 277(35): 32220 - 32227. [Abstract] [Full Text] [PDF]

				M. Toth, S. Hernandez-Barrantes, P. Osenkowski, M. M. Bernardo, D. C. Gervasi, Y. Shimura, O. Meroueh, L. P. Kotra, B. G. Galvez, A. G. Arroyo, et al. Complex Pattern of Membrane Type 1 Matrix Metalloproteinase Shedding. REGULATION BY AUTOCATALYTIC CELL SURFACE INACTIVATION OF ACTIVE ENZYME J. Biol. Chem., July 12, 2002; 277(29): 26340 - 26350. [Abstract] [Full Text] [PDF]

				H. Palosaari, Y. Ding, M. Larmas, T. Sorsa, J.D. Bartlett, T. Salo, and L. Tjaderhane Regulation and Interactions of MT1-MMP and MMP-20 in Human Odontoblasts and Pulp Tissue in vitro J. Dent. Res., May 1, 2002; 81(5): 354 - 359. [Abstract] [Full Text] [PDF]

				K. Lehti, J. Lohi, M. M. Juntunen, D. Pei, and J. Keski-Oja Oligomerization through Hemopexin and Cytoplasmic Domains Regulates the Activity and Turnover of Membrane-type 1 Matrix Metalloproteinase J. Biol. Chem., March 1, 2002; 277(10): 8440 - 8448. [Abstract] [Full Text] [PDF]

				W. R. English, B. Holtz, G. Vogt, V. Knauper, and G. Murphy Characterization of the Role of the "MT-loop". AN EIGHT-AMINO ACID INSERTION SPECIFIC TO PROGELATINASE A (MMP2) ACTIVATING MEMBRANE-TYPE MATRIX METALLOPROTEINASES J. Biol. Chem., November 2, 2001; 276(45): 42018 - 42026. [Abstract] [Full Text] [PDF]

				E. Frisdal, V. Gest, A. Vieillard-Baron, M. Levame, H. Lepetit, S. Eddahibi, C. Lafuma, A. Harf, S. Adnot, and M-;P. d'Ortho Gelatinase expression in pulmonary arteries during experimental pulmonary hypertension Eur. Respir. J., November 1, 2001; 18(5): 838 - 845. [Abstract] [Full Text] [PDF]

				E. Toschi, G. Barillari, C. Sgadari, I. Bacigalupo, A. Cereseto, D. Carlei, C. Palladino, C. Zietz, P. Leone, M. Sturzl, et al. Activation of Matrix-Metalloproteinase-2 and Membrane-Type-1-Matrix-Metalloproteinase in Endothelial Cells and Induction of Vascular Permeability In Vivo by Human Immunodeficiency Virus-1 Tat Protein and Basic Fibroblast Growth Factor Mol. Biol. Cell, October 1, 2001; 12(10): 2934 - 2946. [Abstract] [Full Text] [PDF]

				S. Aznavoorian, B. A. Moore, L. D. Alexander-Lister, S. L. Hallit, L. J. Windsor, and J. A. Engler Membrane Type I-Matrix Metalloproteinase-Mediated Degradation of Type I Collagen by Oral Squamous Cell Carcinoma Cells Cancer Res., August 1, 2001; 61(16): 6264 - 6275. [Abstract] [Full Text] [PDF]

				J. Longin, P. Guillaumot, M.-A. Chauvin, A.-M. Morera, and B. Le Magueresse-Battistoni MT1-MMP in rat testicular development and the control of Sertoli cell proMMP-2 activation J. Cell Sci., January 6, 2001; 114(11): 2125 - 2134. [Abstract] [Full Text] [PDF]

				J. MARTIN, L. EYNSTONE, M. DAVIES, and R. STEADMAN Induction of Metalloproteinases by Glomerular Mesangial Cells Stimulated by Proteins of the Extracellular Matrix J. Am. Soc. Nephrol., January 1, 2001; 12(1): 88 - 96. [Abstract] [Full Text]