spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Signoret, N.
Right arrow Articles by Marsh, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Signoret, N.
Right arrow Articles by Marsh, M.
Acres, B. R., Conlon, P. J., Mochizuki, D. Y. and Gallis, B (1986). Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen. J. Biol. Chem 34, 16210-16214.

Alkhatib, G., Combadiere, C., Broder, C. C., Feng, Y., Kennedy, P. E., Murphy, P. M. and Berger, E. A (1996). CC-CKR5: A RANTES, MIP-1, MIP-1 receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272, 1955-1958.[Abstract]

Alkhatib, G., Liao, F., Berger, E. A., Farber, J. M. and Peden, K. W. C (1997). A new SIV co-receptor STRL33. Nature 388, 238-.[Medline]

Amara, A., Gall, S. L., Schwartz, O., Salamero, J., Montes, M., Loetscher, P., Baggiolini, M., Virelizier, J. L. and Arenzana-Seisdedos, F (1997). HIV Coreceptor Downregulation as Antiviral Principle: SDF-1alpha-dependent Internalization of the Chemokine Receptor CXCR4 Contributes to Inhibition of HIV Replication. J. Exp. Med 186, 139-146.[Abstract/Free Full Text]

Arai, H., Monteclaro, F. S., Tsou, C.-L., Franci, C. and Charo, I. F (1997). Dissociation of chemotaxis from agonist-induced receptor internalisation in a lymphocyte cell line transformed with CCR2B. J. Biol. Chem 272, 25037-25042.[Abstract/Free Full Text]

Aramori, I., Zhang, J., Ferguson, S. S., Bieniasz, P. D., Cullen, B. R. and Caron, M. G (1997). Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor. EMBO J 16, 4606-4616.[Medline]

Arenzana-Seisdedos, F., Virelizier, J.-L., Rousset, D., Clark-Lewis, I., Loetscher, P., Moser, B. and Baggiolini, M (1996). HIV blocked by HIV chemokine antagonists. Nature 383, 400-.[Medline]

Ben-Baruch, A., Bengali, K. M., Biragyn, A., Johnston, J. J., Wang, J. M., Kim, J., Chuntharapai, A., Michiel, D. F., Oppenheim, J. J., et al (1995). Interleukin-8 receptor beta. The role of the carboxyl terminus in signal transduction. J. Biol. Chem 270, 9121-9128.[Abstract/Free Full Text]

Berger, E. A (1997). HIV entry and tropism: the chemokine receptor connection. AIDS 11, 3-.

Berger, E. A., Doms, R. W., Feny\232, E.-M., Korber, B. T. M., Littman, D. R., Moore, J. P., Sattentau, Q. J., Schuitemaker, H., Sodroski, J., et al (1998). A new classification for HIV-1. Nature 391, 240-.[Medline]

Berson, J. F., Long, D., Doranz, B. J., Rucker, J., Jirik, F. R. and Doms, R. W (1996). A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. J. Virol 70, 6288-6295.[Abstract]

Bleul, C. C., Farzan, M., Choe, H., Parolin, C., Clark-Lewis, I., Sodroski, J. and Springer, T. A (1996). The lymphocyte chemoattractant SDF-1 is a ligand for Lestr/fusin and blocks HIV-1 entry. Nature 382, 829-832.[Medline]

Bleul, C. C., Wu, L. J., Hoxie, J. A., Springer, T. A. and Mackay, C. R (1997). The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc. Nat. Acad. Sci. USA 94, 1925-1930.[Abstract/Free Full Text]

Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., Wu, L., C.R., M., LaRosa, G., et al (1996). The-Chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85, 1135-1148.[Medline]

Cocchi, F., DeVico, A. L., Garzino-Demo, A., Arya, S. K., Gallo, R. C. and Lusso, P (1995). Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science 270, 1811-1815.[Abstract/Free Full Text]

Crump, M. P., Gong, J. H., Loetscher, P., Rajarathnam, K., Amara, A., Arenzana-Seisdedos, F., Virelizier, J. L., Baggiolini, M., Sykes, B. D., et al (1997). Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J 16, 6996-7007.[Medline]

Deng, H., Liu, R., Ellmeier, W., Choe, S., Unutmaz, D., Burkhart, M., Di Marzio, P., Marmon, S., Sutton, R. E., et al (1996). Identification of a major co-receptor for primary isolates of HIV-1. Nature 381, 661-666.[Medline]

Deng, H., Unutmaz, D., KewalRamani, V. N. and Littman, D. R (1997). Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 388, 296-300.[Medline]

Dietrich, J., Hou, X., Wegener, A.-M. and Geisler, C (1994). CD3contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor. EMBO J 13, 2156-2166.[Medline]

Dietrich, J., Kastrup, J., Nielsen, B. L., Odum, N. and Geisler, C (1997). Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro. J. Cell Biol 138, 271-281.[Abstract/Free Full Text]

Doranz, B. J., Rucker, J., Yi, Y., Smyth, R. J., Samson, M., Peiper, S., Parmentier, M., Collman, R. J. and Doms, R. W (1996). A dual-tropic, primary HIV-1 isolate that uses Fusin and the \247-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 85, 1149-1158.[Medline]

Dragic, T., Litwin, V., Allaway, G. P., Martin, S. R., Huang, Y., Nagashima, K. A., Cayanan, C., Maddon, P. J., Koup, R. A., et al (1996). HIV-1 entry into CD4+cells is mediated by the chemokine receptor CC-CKR-5. Nature 381, 667-673.[Medline]

Edinger, A. L., Amedee, A., Miller, K., Doranz, B. J., Endres, M., Sharron, M., Samson, M., Lu, Z. H., Clements, J. E., et al (1997). Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains. Proc. Nat. Acad. Sci. USA 94, 4005-4010.[Abstract/Free Full Text]

Endres, M. J., Clapham, P. R., Marsh, M., Ahuja, M., Davis-Turner, J., McKnight, A., Thomas, J., Stoebenau-Haggarty, B., Choe, S., et al (1996). CD4-independent infection by HIV-2 is mediated by fusin. Cell 87, 745-756.[Medline]

Farzan, M., Choe, H., Martin, K., Marcon, L., Hofmann, W., Karlsson, G., Sun, Y., Barrett, P., Marchand, N., et al (1997). Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. J. Exp. Med 186, 405-411.[Abstract/Free Full Text]

Feng, Y., Broder, C. C., Kennedy, P. E. and Berger, E. A (1996). HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272, 872-877.[Abstract]

Ferguson, S. S., Barak, L. S., Zhang, J. and Caron, M. G (1996). G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins. Can. J. Physiol. Pharmacol 74, 1095-1110.[Medline]

Ferguson, S. S., Downey, W. E. r., Colapietro, A. M., Barak, L. S.,Menard, L. and Caron, M. G (1996). Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271, 363-366.[Abstract]

Forster, R., Kremmer, E., Schubel, A., Breitfeld, D., Kleinschmidt, A., Nerl, C., Bernhardt, G. and Lipp, M (1998). Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation. J. Immunol 160, 1522-1531.[Abstract/Free Full Text]

Fouchier, R. A., Meyer, B. E., Simon, J. H., Fischer, U. and Malim, M. H (1997). HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import. EMBO J 16, 4531-4539.[Medline]

Godiska, R., Chantry, D., Raport, C. J., Schweickart, V. L., Trong, H. L. and Gray, P. W (1997). Monocyte chemotactic protein-4: tissue-specific expression and signaling through CC chemokine receptor-2. J. Leukoc. Biol 61, 353-60.[Abstract]

Goodman, O. B., Krupnick, J. G., Santinin, F., Gurevich, V. V., Penn, R. B., Gagnon, A. W., Keen, J. H. and Benovic, J. L (1996). -Arrestin acts as a clathrin adaptor in endocytosis of the 2-adrenergic receptor. Nature 383, 447-450.[Medline]

Goodman, O. B., Krupnick, J. G., Gurevich, V. V., Benovic, J. L. and Keen, J. H (1997). Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain. J. Biol. Chem 272, 15017-15022.[Abstract/Free Full Text]

Gunn, M. D., Ngo, V. N., Ansel, K. M., Ekland, E. H., Cyster, J. G. and Williams, L. T (1998). A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature 391, 799-803.[Medline]

Gupta, K., Lysko, P. G., Pillarisetti, K., Ohlstein, E. and Stadel, J. M (1998). Chemokine receptors in human endothelial cells. J. Biol. Chem 273, 4282-4287.[Abstract/Free Full Text]

Haribabu, B., Richardson, R. M., Fisher, I., Sozzani, S., Peiper, S. C., Horuk, R., Ali, H. and Snyderman, R (1997). Regulation of human chemokine receptors CXCR4: Role of phosphorylation in desensitization and internalization. J. Biol. Chem 272, 28726-28731.[Abstract/Free Full Text]

He, J., Chen, Y., Farzan, M., Choe, H., Ohagen, A., Gartner, S., Busciglio, J., Yang, X., Hofmann, W., et al (1997). CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 385, 645-649.[Medline]

Healey, D., Dianda, L., Moore, J. P., McDougal, J. S., Moore, M. J., Estess, P., Buck, D., Kwong., P. D., Beverley, P. C. L., et al (1990). Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding. J. Exp. Med 172, 1233-1242.[Abstract/Free Full Text]

Hesselgesser, J., HalksMiller, M., DelVecchio, V., Peiper, S. C., Hoxie, J., Kolson, D. L., Taub, D. and Horuk, R (1997). CD4-independent association between HIV-1 gp120 and CXCR4: Functional chemokine receptors are expressed in human neurons. Curr. Biol 7, 112-121.[Medline]

Hoxie, J. A., Rackowski, J. L., Haggarty, B. S. and Gaulton, G. N (1988). T4 Endocytosis and phosphorylation induced by phorbol esters but not by mitogen or HIV infection. J. Immunol 140, 786-795.[Abstract]

Hoxie, J. A., Ahuja, M., Belmonte, E., Pizarro, S., Parton, R. and Brass, L. F (1993). Internalization and recycling of activated thrombin receptors. J. Biol. Chem 268, 13756-13763.[Abstract/Free Full Text]

Johansen, T. E., Scholler, M. S., Tolstoy, S. and Schwartz, T. W (1990). Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors. FEBS Lett 267, 289-294.[Medline]

Jourdan, P., Abbal, C., Nora, N., Hori, T., Uchiyama, T., Vendrell, J. P., Bousquet, J., Taylor, N., Pene, J., et al (1998). IL-4 induces functional cell-surface expression of CXCR4 on human T cells. J. Immunol 160, 4153-4157.[Abstract/Free Full Text]

Kledal, T. N., Rosenkilde, M. M., Coulin, F., Simmons, G., Johnsen, A. H., Alouani, S., Power, C. A., Luttichau, H. R., Gerstoft, J., et al (1997). A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus. Science 277, 1656-1659.[Abstract/Free Full Text]

Krueger, K. M., Daaka, Y., Pitcher, J. A. and Lefkowitz, R. J (1997). The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification. J. Biol. Chem 272, 5-8.[Abstract/Free Full Text]

Lapham, C. K., Quyang, J., Chandrasekhar, B., Nguyen, N. Y., Dimitrov, D. S. and Golding, H (1996). Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines. Science 274, 602-605.[Abstract/Free Full Text]

Liu, R., Paxton, W. A., Choe, S., Ceradini, D., Martin, S. R., Horuk, R., MacDonald, S. R., Stuhlmann, H., Koup, R. A., et al (1996). Homozygous defect in HIV-1 co-receptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86, 367-377.[Medline]

Mack, M., Luckow, B., Nelson, P. J., Cihak, J., Simmons, G., Clapham, P. R., Signoret, N., Marsh, M., Stangassinger, F., et al (1998). Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity. J. Exp. Med 187, 1215-1224.[Abstract/Free Full Text]

Maddon, P. J., McDougal, J. S., Clapham, P. R., Dalgleish, A. G., Jamal, S., Weiss, R. A. and Axel, R (1988). HIV infection does not require endocytosis of its receptor, CD4. Cell 54, 865-874.[Medline]

Marsh, M. and Pelchen-Matthews, A (1996). Endocytic and exocytic regulation of CD4 expression and function. Curr. Top. Microbiol. Immunol 205, 107-135.[Medline]

Menard, L., Ferguson, S. S., Zhang, J., Lin, F. T., Lefkowitz, R. J., Caron, M. G. and Barak, L. S (1997). Synergistic regulation of beta2-adrenergic receptor sequestration: intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization. Mol. Pharmacol 51, 800-808.[Abstract/Free Full Text]

Moore, J. P., Trkola, A. and Dragic, T (1997). Co-receptors for HIV-1 entry. Curr. Opin. Immunol 9, 551-562.[Medline]

Morgenstern, J. P. and Land, H (1990). Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and complementary helper-free packaging cell line. Nucl. Acids Res 18, 3587-3596.[Abstract/Free Full Text]

Mueller, S. G., White, J. R., Schraw, W. P., Lam, V. and Richmond, A (1997). Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor. J. Biol. Chem 272, 8207-8214.[Abstract/Free Full Text]

Murphy, P. M (1994). The molecular biology of leukocyte chemoattractant factors. Annu. Rev. Immunol 12, 593-633.[Medline]

Nagasawa, T., Hirota, S., Tachibana, K., Takakura, N., Nishikawa, S.-I., Kitamura, Y., Yoshida, N., Kikutani, H. and Kishimoto, T (1996). Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 382, 635-638.[Medline]

Oberlin, E., Amara, A., Bacherlerie, F., Bessia, C., Virelizier, J.-L., Arenzana-Seisdedos, F., Schwartz, O., Heard, J.-M., Clark-Lewis, I., et al (1996). The CXC chemokine SDF-1 is the ligand for Lestr/Fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 382, 833-835.[Medline]

Orloff, G. M., Orloff, S. L., Kennedy, M. S., Maddon, P. J. and McDougal, J. S (1991). Penetration of CD4 T cells by HIV-1. The CD4 receptor does not internalise with HIV and CD4-related signal transduction events are not required for entry. J. Immunol 146, 2578-2587.[Abstract]

Pelchen-Matthews, A., Armes, J. E. and Marsh, M (1989). Internalization and recycling of CD4 transfected into HeLa and NIH-3T3 cells. EMBO J 8, 3641-3649.[Medline]

Pelchen-Matthews, A., Armes, J. E., Griffiths, G. and Marsh, M (1991). Differencial endocytosis of CD4 in lymphocytic and non-lymphocytic cells. J. Exp. Med 173, 575-587.[Abstract/Free Full Text]

Pelchen-Matthews, A., Parsons, I. J. and Marsh, M (1993). Phorbol ester-induced down-regulation of CD4 is a multi-step process involving dissociation from p56lck, increased association with clathrin-coated pits and altered endosomal sorting. J. Exp. Med 178, 1209-1222.[Abstract/Free Full Text]

Pelchen-Matthews, A., Clapham, P. and Marsh, M (1995). The role of CD4 endocytosis in HIV infection. J. Virol 69, 8164-8168.[Abstract]

Prado, G. N., Suzuki, H., Wilkinson, N., Cousins, B. and Navarro, J (1996). Role of the C terminus of the interleukin 8 receptor in signal transduction and internalization. J. Biol. Chem 271, 19186-19190.[Abstract/Free Full Text]

Rosenkilde, M. M., Cahir, M., Gether, U., Hjorth, S. A. and Schwartz, T. W (1994). Mutations along transmembrane segment II of the NK-1 receptor affect substance P competition with non peptide antagonists but not substance P binding. J. Biol. Chem 269, 28160-28164.[Abstract/Free Full Text]

Samson, M., Libert, F., Doranz, B. J., Rucker, J., Liesnard, C., Farber, C.-M., Saragosti, S., Lapoumeroulie, C., Cognaux, J., et al (1996). Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382, 722-725.[Medline]

Shin, J., Dunbrack, R. L., Lee, S. and Strominger, J. L (1991). Phosphorylation-dependent down-modulation of CD4 requires a specific structure within the cytoplasmic domain of CD4. J. Biol. Chem 266, 10658-10665.[Abstract/Free Full Text]

Signoret, N., Oldridge, J., Pelchen-Matthews, A., Klasse, P. J., Tran, T., Brass, L. F., Rosenkilde, M. M., Schwartz, T. W., Holmes, W., et al (1997). Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. J. Cell Biol 139, 651-664.[Abstract/Free Full Text]

Simmons, G., Clapham, P. R., Picard, L., Offord, R. E., Rosenkilde, M. M., Schwartz, T. W., Buser, R., Wells, T. N. C. and Proudfoot, A. E (1997). Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist. Science 276, 276-279.[Abstract/Free Full Text]

Solari, R., Offord, R. E., Remy, S., Aubry, J. P., Wells, T. N. C., Whitehorn, E., Oung, T. and Proudfoot, A. E. I (1997). Receptor-mediated Endocytosis of CC-chemokines. J. Biol. Chem 272, 9617-9620.[Abstract/Free Full Text]

Tachibana, K., Hirota, S., Iizasa, H., Yoshida, H., Kawabata, K., Kataoka, Y., Kitamura, Y., Matsushima, K., Yoshida, N., et al (1998). The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393, 591-594.[Medline]

Trkola, A., Dragic, T., Arthos, J., Binley, J. M., Olson, W. C., Allaway, G. P., Chenh-Mayer, C., Robinson, J., Maddon, P. J., et al (1996). CD4-dependent, antibody sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature 384, 184-187.[Medline]

Ugolini, S., Moulard, M., Mondor, I., Barois, N., Demandolx, D., Hoxie, J., Brelot, A., Alizon, M., Davoust, J., et al (1997). HIV-1 gp120 induces an association between CD4 and the chemokine receptor CXCR4. J. Immunol 159, 3000-3008.[Abstract]

Volin, M. V., Joseph, L., Shockley, M. S. and Davies, P. F (1998). Chemokine receptor CXCR4 expression in endothelium. Biochem. Biophys. Res. Commun 242, 46-53.[Medline]

von Zastrow, M. and Kolbika, B. K (1992). Ligand-regulated internalization and recycling of human2-adrenergic receptors between the plasma membrane and endosomes containing the transferrin receptor. J. Biol. Chem 267, 3530-3538.[Abstract/Free Full Text]

Wells, T. N. C., Proudfoot, A. E. I., Power, C. A. and Marsh, M (1996). Chemokine receptors \320 the new frontier for AIDS research. Chem. Biol 3, 603-609.[Medline]

Zhang, J., Ferguson, S. S. G., Barak, L. S., Menard, L. and Caron, M. G (1996). Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization. J. Biol. Chem 271, 18302-18305.[Abstract/Free Full Text]

Zou, Y.-R., Kottmann, A. H., Kuroda, M., Taniuchi, I. and Littman, D. R (1998). Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393, 595-599.[Medline]


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
R. L. Contento, B. Molon, C. Boularan, T. Pozzan, S. Manes, S. Marullo, and A. Viola
CXCR4-CCR5: A couple modulating T cell functions
PNAS, July 22, 2008; 105(29): 10101 - 10106.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. M. Rosenkilde, L.-O. Gerlach, S. Hatse, R. T. Skerlj, D. Schols, G. J. Bridger, and T. W. Schwartz
Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the CXCR4 Chemokine Receptor
J. Biol. Chem., September 14, 2007; 282(37): 27354 - 27365.
[Abstract] [Full Text] [PDF]

Home page
 Molecular Cancer TherapeuticsHome page
Z. Zeng, I. J. Samudio, M. Munsell, J. An, Z. Huang, E. Estey, M. Andreeff, and M. Konopleva
Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias
Mol. Cancer Ther., December 1, 2006; 5(12): 3113 - 3121.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
S. Venzke, N. Michel, I. Allespach, O. T. Fackler, and O. T. Keppler
Expression of Nef Downregulates CXCR4, the Major Coreceptor of Human Immunodeficiency Virus, from the Surfaces of Target Cells and Thereby Enhances Resistance to Superinfection
J. Virol., November 15, 2006; 80(22): 11141 - 11152.
[Abstract] [Full Text] [PDF]

Home page
 Molecular Cancer TherapeuticsHome page
J. Wang, L. He, C. A. Combs, G. Roderiquez, and M. A. Norcross
Dimerization of CXCR4 in living malignant cells: control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions.
Mol. Cancer Ther., October 1, 2006; 5(10): 2474 - 2483.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
C. Otero, M. Groettrup, and D. F. Legler
Opposite Fate of Endocytosed CCR7 and Its Ligands: Recycling versus Degradation
J. Immunol., August 15, 2006; 177(4): 2314 - 2323.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
N. Michel, K. Ganter, S. Venzke, J. Bitzegeio, O. T. Fackler, and O. T. Keppler
The Nef Protein of Human Immunodeficiency Virus Is a Broad-Spectrum Modulator of Chemokine Receptor Cell Surface Levels That Acts Independently of Classical Motifs for Receptor Endocytosis and G{alpha}i Signaling
Mol. Biol. Cell, August 1, 2006; 17(8): 3578 - 3590.
[Abstract] [Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
F. Nimura, L. F. Zhang, K. Okuma, R. Tanaka, H. Sunakawa, N. Yamamoto, and Y. Tanaka
Cross-linking cell surface chemokine receptors leads to isolation, activation, and differentiation of monocytes into potent dendritic cells.
Experimental Biology and Medicine, April 1, 2006; 231(4): 431 - 443.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. Infantino, B. Moepps, and M. Thelen
Expression and Regulation of the Orphan Receptor RDC1 and Its Putative Ligand in Human Dendritic and B Cells
J. Immunol., February 15, 2006; 176(4): 2197 - 2207.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
F. Huttenrauch, B. Pollok-Kopp, and M. Oppermann
G Protein-coupled Receptor Kinases Promote Phosphorylation and {beta}-Arrestin-mediated Internalization of CCR5 Homo- and Hetero-oligomers
J. Biol. Chem., November 11, 2005; 280(45): 37503 - 37515.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
V. Monceaux, L. Viollet, F. Petit, R. H. T. Fang, M.-C. Cumont, J. Zaunders, B. Hurtrel, and J. Estaquier
CD8+ T Cell Dynamics during Primary Simian Immunodeficiency Virus Infection in Macaques: Relationship of Effector Cell Differentiation with the Extent of Viral Replication
J. Immunol., June 1, 2005; 174(11): 6898 - 6908.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
K. Balabanian, B. Lagane, J. L. Pablos, L. Laurent, T. Planchenault, O. Verola, C. Lebbe, D. Kerob, A. Dupuy, O. Hermine, et al.
WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12
Blood, March 15, 2005; 105(6): 2449 - 2457.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
F. Pujol, P. Kitabgi, and H. Boudin
The chemokine SDF-1 differentially regulates axonal elongation and branching in hippocampal neurons
J. Cell Sci., March 1, 2005; 118(5): 1071 - 1080.
[Abstract] [Full Text] [PDF]

Home page
 Biophys. JHome page
M. Peter, S. M. Ameer-Beg, M. K. Y. Hughes, M. D. Keppler, S. Prag, M. Marsh, B. Vojnovic, and T. Ng
Multiphoton-FLIM Quantification of the EGFP-mRFP1 FRET Pair for Localization of Membrane Receptor-Kinase Interactions
Biophys. J., February 1, 2005; 88(2): 1224 - 1237.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
N. Signoret, L. Hewlett, S. Wavre, A. Pelchen-Matthews, M. Oppermann, and M. Marsh
Agonist-induced Endocytosis of CC Chemokine Receptor 5 Is Clathrin Dependent
Mol. Biol. Cell, February 1, 2005; 16(2): 902 - 917.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
K. Princen, S. Hatse, K. Vermeire, S. Aquaro, E. De Clercq, L.-O. Gerlach, M. Rosenkilde, T. W. Schwartz, R. Skerlj, G. Bridger, et al.
Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist
J. Virol., December 1, 2004; 78(23): 12996 - 13006.
[Abstract] [Full Text] [PDF]

Home page
 Stem CellsHome page
Y. Zhang, A. Foudi, J.-F. Geay, M. Berthebaud, D. Buet, P. Jarrier, A. Jalil, W. Vainchenker, and F. Louache
Intracellular Localization and Constitutive Endocytosis of CXCR4 in Human CD34+ Hematopoietic Progenitor Cells
Stem Cells, November 1, 2004; 22(6): 1015 - 1029.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. M. Rosenkilde, L.-O. Gerlach, J. S. Jakobsen, R. T. Skerlj, G. J. Bridger, and T. W. Schwartz
Molecular Mechanism of AMD3100 Antagonism in the CXCR4 Receptor: TRANSFER OF BINDING SITE TO THE CXCR3 RECEPTOR
J. Biol. Chem., January 23, 2004; 279(4): 3033 - 3041.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
S. Venkatesan, J. J. Rose, R. Lodge, P. M. Murphy, and J. F. Foley
Distinct Mechanisms of Agonist-induced Endocytosis for Human Chemokine Receptors CCR5 and CXCR4
Mol. Biol. Cell, August 1, 2003; 14(8): 3305 - 3324.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
N. Schmitt, L. Chene, D. Boutolleau, M.-T. Nugeyre, E. Guillemard, P. Versmisse, C. Jacquemot, F. Barre-Sinoussi, and N. Israel
Positive Regulation of CXCR4 Expression and Signaling by Interleukin-7 in CD4+ Mature Thymocytes Correlates with Their Capacity To Favor Human Immunodeficiency X4 Virus Replication
J. Virol., May 15, 2003; 77(10): 5784 - 5793.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
C. M. Steffens and T. J. Hope
Localization of CD4 and CCR5 in Living Cells
J. Virol., April 15, 2003; 77(8): 4985 - 4991.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Shackleton, I. Hamer, M. Foti, N. Zumwald, C. Maeder, and J.-L. Carpentier
Role of Two Dileucine-like Motifs in Insulin Receptor Anchoring to Microvilli
J. Biol. Chem., November 8, 2002; 277(46): 43631 - 43637.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. Guan, J. Wang, G. Roderiquez, and M. A. Norcross
Natural Truncation of the Chemokine MIP-1beta /CCL4 Affects Receptor Specificity but Not Anti-HIV-1 Activity
J. Biol. Chem., August 23, 2002; 277(35): 32348 - 32352.
[Abstract] [Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
P. Cockwell, J. W. Calderwood, C. J. Brooks, S. J. Chakravorty, and C. O. S. Savage
Chemoattraction of T cells expressing CCR5, CXCR3 and CX3CR1 by proximal tubular epithelial cell chemokines
Nephrol. Dial. Transplant., May 1, 2002; 17(5): 734 - 744.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
A. Sauty, R. A. Colvin, L. Wagner, S. Rochat, F. Spertini, and A. D. Luster
CXCR3 Internalization Following T Cell-Endothelial Cell Contact: Preferential Role of IFN-Inducible T Cell {alpha} Chemoattractant (CXCL11)
J. Immunol., December 15, 2001; 167(12): 7084 - 7093.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
L. M. Ebert and S. R. McColl
Coregulation of CXC Chemokine Receptor and CD4 Expression on T Lymphocytes During Allogeneic Activation
J. Immunol., April 15, 2001; 166(8): 4870 - 4878.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
N. Signoret, A. Pelchen-Matthews, M. Mack, A. E.I. Proudfoot, and M. Marsh
Endocytosis and Recycling of the HIV Coreceptor CCR5
J. Cell Biol., December 11, 2000; 151(6): 1281 - 1294.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
D. Unutmaz, W. Xiang, M. J. Sunshine, J. Campbell, E. Butcher, and D. R. Littman
The Primate Lentiviral Receptor Bonzo/STRL33 Is Coordinately Regulated with CCR5 and Its Expression Pattern Is Conserved Between Human and Mouse
J. Immunol., September 15, 2000; 165(6): 3284 - 3292.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
C. Albanesi, C. Scarponi, S. Sebastiani, A. Cavani, M. Federici, O. De Pita, P. Puddu, and G. Girolomoni
IL-4 Enhances Keratinocyte Expression of CXCR3 Agonistic Chemokines
J. Immunol., August 1, 2000; 165(3): 1395 - 1402.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. J. Orsini, J.-L. Parent, S. J. Mundell, and J. L. Benovic
Trafficking of the HIV Coreceptor CXCR4. ROLE OF ARRESTINS AND IDENTIFICATION OF RESIDUES IN THE C-TERMINAL TAIL THAT MEDIATE RECEPTOR INTERNALIZATION
J. Biol. Chem., October 22, 1999; 274(43): 31076 - 31086.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
P. J. Klasse, M. M. Rosenkilde, N. Signoret, A. Pelchen-Matthews, T. W. Schwartz, and M. Marsh
CD4-Chemokine Receptor Hybrids in Human Immunodeficiency Virus Type 1 Infection
J. Virol., September 1, 1999; 73(9): 7453 - 7466.
[Abstract] [Full Text]

Home page
 J. Exp. Med.Home page
R. Guinamard, N. Signoret, M. Ishiai, M. Marsh, T. Kurosaki, and J. V. Ravetch
B Cell Antigen Receptor Engagement Inhibits Stromal Cell-derived Factor (SDF)-1alpha Chemotaxis and Promotes Protein Kinase C (PKC)-induced Internalization of CXCR4
J. Exp. Med., May 3, 1999; 189(9): 1461 - 1466.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
C. Pitcher, S. Höning, A. Fingerhut, K. Bowers, and M. Marsh
Cluster of Differentiation Antigen 4 () Endocytosis and Adaptor Complex Binding Require Activation of the Endocytosis Signal by Serine Phosphorylation
Mol. Biol. Cell, March 1, 1999; 10(3): 677 - 691.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
J. R. Townson, G. J. Graham, N. R. Landau, B. Rasala, and R. J. B. Nibbs
Aminooxypentane Addition to the Chemokine Macrophage Inflammatory Protein-1alpha P Increases Receptor Affinities and HIV Inhibition
J. Biol. Chem., December 8, 2000; 275(50): 39254 - 39261.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
L. O. Gerlach, R. T. Skerlj, G. J. Bridger, and T. W. Schwartz
Molecular Interactions of Cyclam and Bicyclam Non-peptide Antagonists with the CXCR4 Chemokine Receptor
J. Biol. Chem., April 20, 2001; 276(17): 14153 - 14160.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. Wang, E. Guan, G. Roderiquez, V. Calvert, R. Alvarez, and M. A. Norcross
Role of Tyrosine Phosphorylation in Ligand-independent Sequestration of CXCR4 in Human Primary Monocytes-Macrophages
J. Biol. Chem., December 21, 2001; 276(52): 49236 - 49243.
[Abstract] [Full Text] [PDF]

This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Signoret, N.
Right arrow Articles by Marsh, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Signoret, N.
Right arrow Articles by Marsh, M.