Disruption of Dictyostelium PI3K genes reduces [32P]phosphatidylinositol 3,4 bisphosphate and [32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis

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				L. D. Kojic, B. Joshi, P. Lajoie, P. U. Le, M. E. Cox, D. A. Turbin, S. M. Wiseman, and I. R. Nabi Raft-dependent Endocytosis of Autocrine Motility Factor Is Phosphatidylinositol 3-Kinase-dependent in Breast Carcinoma Cells J. Biol. Chem., October 5, 2007; 282(40): 29305 - 29313. [Abstract] [Full Text] [PDF]

				D. Wessels, D. F. Lusche, S. Kuhl, P. Heid, and D. R. Soll PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis J. Cell Sci., August 1, 2007; 120(15): 2517 - 2531. [Abstract] [Full Text] [PDF]

				X. Xu, A. Muller-Taubenberger, K. E. Adley, N. Pawolleck, V. W. Y. Lee, C. Wiedemann, T. S. Sihra, M. Maniak, T. Jin, and R. S. B. Williams Attenuation of Phospholipid Signaling Provides a Novel Mechanism for the Action of Valproic Acid Eukaryot. Cell, June 1, 2007; 6(6): 899 - 906. [Abstract] [Full Text] [PDF]

				I. Keizer-Gunnink, A. Kortholt, and P. J.M. Van Haastert Chemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling J. Cell Biol., May 21, 2007; 177(4): 579 - 585. [Abstract] [Full Text] [PDF]

				H. M. Loovers, M. Postma, I. Keizer-Gunnink, Y. E. Huang, P. N. Devreotes, and P. J.M. van Haastert Distinct Roles of PI(3,4,5)P3 during Chemoattractant Signaling in Dictyostelium: A Quantitative In Vivo Analysis by Inhibition of PI3-Kinase Mol. Biol. Cell, April 1, 2006; 17(4): 1503 - 1513. [Abstract] [Full Text] [PDF]

				F. I. Comer and C. A. Parent Phosphoinositide 3-Kinase Activity Controls the Chemoattractant-mediated Activation and Adaptation of Adenylyl Cyclase Mol. Biol. Cell, January 1, 2006; 17(1): 357 - 366. [Abstract] [Full Text] [PDF]

				D. Dormann, G. Weijer, S. Dowler, and C. J. Weijer In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis J. Cell Sci., December 15, 2004; 117(26): 6497 - 6509. [Abstract] [Full Text] [PDF]

				Y. E. Huang, M. Iijima, C. A. Parent, S. Funamoto, R. A. Firtel, and P. Devreotes Receptor-mediated Regulation of PI3Ks Confines PI(3,4,5)P3 to the Leading Edge of Chemotaxing Cells Mol. Biol. Cell, May 1, 2003; 14(5): 1913 - 1922. [Abstract] [Full Text] [PDF]

				N. Araki, T. Hatae, A. Furukawa, and J. A. Swanson Phosphoinositide-3-kinase-independent contractile activities associated with Fc{gamma}-receptor-mediated phagocytosis and macropinocytosis in macrophages J. Cell Sci., January 15, 2003; 116(2): 247 - 257. [Abstract] [Full Text] [PDF]

				A. Rupper, K. Lee, D. Knecht, and J. Cardelli Sequential Activities of Phosphoinositide 3-Kinase, PKB/Akt, and Rab7 during Macropinosome Formation in Dictyostelium Mol. Biol. Cell, September 1, 2001; 12(9): 2813 - 2824. [Abstract] [Full Text] [PDF]

				S. Funamoto, K. Milan, R. Meili, and R. A. Firtel Role of Phosphatidylinositol 3' Kinase and a Downstream Pleckstrin Homology Domain-Containing Protein in Controlling Chemotaxis inDictyostelium J. Cell Biol., May 14, 2001; 153(4): 795 - 810. [Abstract] [Full Text] [PDF]

				A. Rupper, J. Rodriguez-Paris, B. Grove, and J. Cardelli p110-related PI 3-kinases regulate phagosome-phagosome fusion and phagosomal pH through a PKB/Akt dependent pathway in Dictyostelium J. Cell Sci., January 4, 2001; 114(7): 1283 - 1295. [Abstract] [PDF]

				M. Amyere, B. Payrastre, U. Krause, P. V. D. Smissen, A. Veithen, and P. J. Courtoy Constitutive Macropinocytosis in Oncogene-transformed Fibroblasts Depends on Sequential Permanent Activation of Phosphoinositide 3-Kinase and Phospholipase C Mol. Biol. Cell, October 1, 2000; 11(10): 3453 - 3467. [Abstract] [Full Text]

				C. Y. Chung, S. Lee, C. Briscoe, C. Ellsworth, and R. A. Firtel Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells PNAS, May 9, 2000; 97(10): 5225 - 5230. [Abstract] [Full Text] [PDF]

				J. Berg, B. Derfler, C. Pennisi, D. Corey, and R. Cheney Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin J. Cell Sci., January 10, 2000; 113(19): 3439 - 3451. [Abstract] [PDF]

				M Khosla, G. Spiegelman, R Insall, and G Weeks Functional overlap of the dictyostelium RasG, RasD and RasB proteins J. Cell Sci., January 4, 2000; 113(8): 1427 - 1434. [Abstract] [PDF]

				A. Noegel and M Schleicher The actin cytoskeleton of Dictyostelium: a story told by mutants J. Cell Sci., January 3, 2000; 113(5): 759 - 766. [Abstract] [PDF]

				J. Chubb, A Wilkins, G. Thomas, and R. Insall The Dictyostelium RasS protein is required for macropinocytosis, phagocytosis and the control of cell movement J. Cell Sci., January 2, 2000; 113(4): 709 - 719. [Abstract] [PDF]

				A. Noegel, F Rivero, R Albrecht, K. Janssen, J Kohler, C. Parent, and M Schleicher Assessing the role of the ASP56/CAP homologue of Dictyostelium discoideum and the requirements for subcellular localization J. Cell Sci., January 10, 1999; 112(19): 3195 - 3203. [Abstract] [PDF]

				D. J. Seastone, E. Lee, J. Bush, D. Knecht, and J. Cardelli Overexpression of a Novel Rho Family GTPase, RacC, Induces Unusual Actin-based Structures and Positively Affects Phagocytosis in Dictyostelium discoideum Mol. Biol. Cell, October 1, 1998; 9(10): 2891 - 2904. [Abstract] [Full Text]

				Y. Leng, T. N. Chase, and M. C. Bennett Muscarinic Receptor Stimulation Induces Translocation of an alpha -Synuclein Oligomer from Plasma Membrane to a Light Vesicle Fraction in Cytoplasm J. Biol. Chem., July 20, 2001; 276(30): 28212 - 28218. [Abstract] [Full Text] [PDF]