H2O2 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells

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				M. Rahmani, E. Reese, Y. Dai, C. Bauer, S. G. Payne, P. Dent, S. Spiegel, and S. Grant Coadministration of Histone Deacetylase Inhibitors and Perifosine Synergistically Induces Apoptosis in Human Leukemia Cells through Akt and ERK1/2 Inactivation and the Generation of Ceramide and Reactive Oxygen Species Cancer Res., March 15, 2005; 65(6): 2422 - 2432. [Abstract] [Full Text] [PDF]

				P. A. Lang, D. S. Kempe, V. Tanneur, K. Eisele, B. A. Klarl, S. Myssina, V. Jendrossek, S. Ishii, T. Shimizu, M. Waidmann, et al. Stimulation of erythrocyte ceramide formation by platelet-activating factor J. Cell Sci., March 15, 2005; 118(6): 1233 - 1243. [Abstract] [Full Text] [PDF]

				J.-A. Gomez, X. Molero, E. Vaquero, A. Alonso, A. Salas, and J.-R. Malagelada Vitamin E attenuates biochemical and morphological features associated with development of chronic pancreatitis Am J Physiol Gastrointest Liver Physiol, July 1, 2004; 287(1): G162 - G169. [Abstract] [Full Text] [PDF]

				J.-T. Lee, J. Xu, J.-M. Lee, G. Ku, X. Han, D.-I Yang, S. Chen, and C. Y. Hsu Amyloid-{beta} peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway J. Cell Biol., January 5, 2004; 164(1): 123 - 131. [Abstract] [Full Text] [PDF]

				T. Kurita-Ochiai, S. Amano, K. Fukushima, and K. Ochiai Cellular Events Involved in Butyric Acid-Induced T Cell Apoptosis J. Immunol., October 1, 2003; 171(7): 3576 - 3584. [Abstract] [Full Text] [PDF]

				T. Ravid, A. Tsaba, P. Gee, R. Rasooly, E. A. Medina, and T. Goldkorn Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells Am J Physiol Lung Cell Mol Physiol, June 1, 2003; 284(6): L1082 - L1092. [Abstract] [Full Text] [PDF]

				D. Martin, M. Salinas, N. Fujita, T. Tsuruo, and A. Cuadrado Ceramide and Reactive Oxygen Species Generated by H2O2 Induce Caspase-3-independent Degradation of Akt/Protein Kinase B J. Biol. Chem., November 1, 2002; 277(45): 42943 - 42952. [Abstract] [Full Text] [PDF]

				K. H. Albertine and C. G. Plopper DNA Oxidation or Apoptosis . Will the Real Culprit of DNA Damage in Hyperoxic Lung Injury Please Stand Up? Am. J. Respir. Cell Mol. Biol., April 1, 2002; 26(4): 381 - 383. [Full Text] [PDF]

				J. R. Hoidal Reactive Oxygen Species and Cell Signaling Am. J. Respir. Cell Mol. Biol., December 1, 2001; 25(6): 661 - 663. [Full Text] [PDF]

				V. Gouaze, M.-E. Mirault, S. Carpentier, R. Salvayre, T. Levade, and N. Andrieu-Abadie Glutathione Peroxidase-1 Overexpression Prevents Ceramide Production and Partially Inhibits Apoptosis in Doxorubicin-Treated Human Breast Carcinoma Cells Mol. Pharmacol., September 1, 2001; 60(3): 488 - 496. [Abstract] [Full Text] [PDF]

				Y. Lee, J. Chen, A. Amoscato, J Bennouna, D. Spitz, M Suntharalingam, and J. Rhee Protective role of Bcl2 in metabolic oxidative stress-induced cell death J. Cell Sci., January 2, 2001; 114(4): 677 - 684. [Abstract] [PDF]

				J.-J. Liu, J.-Y. Wang, E. Hertervig, Y. Cheng, A. Nilsson, and R.-D. Duan ACTIVATION OF NEUTRAL SPHINGOMYELINASE PARTICIPATES IN ETHANOL-INDUCED APOPTOSIS IN HEP G2 CELLS Alcohol Alcohol., November 1, 2000; 35(6): 569 - 573. [Abstract] [Full Text] [PDF]

				K. REZNIKOV, L. KOLESNIKOVA, A. PRAMANIK, K. TAN-NO, I. GILEVA, T. YAKOVLEVA, R. RIGLER, L. TERENIUS, and G. BAKALKIN Clustering of apoptotic cells via bystander killing by peroxides FASEB J, September 1, 2000; 14(12): 1754 - 1764. [Abstract] [Full Text]

				X. Wang, K. D. McCullough, T. F. Franke, and N. J. Holbrook Epidermal Growth Factor Receptor-dependent Akt Activation by Oxidative Stress Enhances Cell Survival J. Biol. Chem., May 5, 2000; 275(19): 14624 - 14631. [Abstract] [Full Text] [PDF]

				O. M. Hernandez, D. J. Discher, N. H. Bishopric, and K. A. Webster Rapid Activation of Neutral Sphingomyelinase by Hypoxia-Reoxygenation of Cardiac Myocytes Circ. Res., February 4, 2000; 86(2): 198 - 204. [Abstract] [Full Text] [PDF]

				H. Sawai, N. Domae, N. Nagan, and Y. A. Hannun Function of the Cloned Putative Neutral Sphingomyelinase as Lyso-platelet Activating Factor-Phospholipase C J. Biol. Chem., December 31, 1999; 274(53): 38131 - 38139. [Abstract] [Full Text] [PDF]

				Rosie Xing and R. Kolesnick Stress signaling of apoptosis via ceramide and c-jun kinase Innate Immunity, August 1, 1999; 5(4): 216 - 221. [Abstract] [PDF]