The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly

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G. Maton, C. Thibier, A. Castro, T. Lorca, C. Prigent, and C. Jessus
Cdc2-Cyclin B Triggers H3 Kinase Activation of Aurora-A in Xenopus Oocytes
J. Biol. Chem., June 6, 2003; 278(24): 21439 - 21449.
[Abstract] [Full Text] [PDF]

S. L. Warner, D. J. Bearss, H. Han, and D. D. Von Hoff
Targeting Aurora-2 Kinase in Cancer
Mol. Cancer Ther., June 1, 2003; 2(6): 589 - 595.
[Abstract] [Full Text] [PDF]

A. Kawajiri, Y. Yasui, H. Goto, M. Tatsuka, M. Takahashi, K.-i. Nagata, and M. Inagaki
Functional Significance of the Specific Sites Phosphorylated in Desmin at Cleavage Furrow: Aurora-B May Phosphorylate and Regulate Type III Intermediate Filaments during Cytokinesis Coordinatedly with Rho-kinase
Mol. Biol. Cell, April 1, 2003; 14(4): 1489 - 1500.
[Abstract] [Full Text] [PDF]

C. Ma, C. Cummings, and X. J. Liu
Biphasic Activation of Aurora-A Kinase during the Meiosis I- Meiosis II Transition in Xenopus Oocytes
Mol. Cell. Biol., March 1, 2003; 23(5): 1703 - 1716.
[Abstract] [Full Text] [PDF]

A. Castro, E. Mandart, T. Lorca, and S. Galas
Involvement of Aurora A Kinase during Meiosis I-II Transition in Xenopus Oocytes
J. Biol. Chem., January 17, 2003; 278(4): 2236 - 2241.
[Abstract] [Full Text] [PDF]

H. Sakai, T. Urano, K. Ookata, M.-H. Kim, Y. Hirai, M. Saito, Y. Nojima, and F. Ishikawa
MBD3 and HDAC1, Two Components of the NuRD Complex, Are Localized at Aurora-A-positive Centrosomes in M Phase
J. Biol. Chem., December 6, 2002; 277(50): 48714 - 48723.
[Abstract] [Full Text] [PDF]

L. E. Littlepage, H. Wu, T. Andresson, J. K. Deanehan, L. T. Amundadottir, and J. V. Ruderman
Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A
PNAS, November 26, 2002; 99(24): 15440 - 15445.
[Abstract] [Full Text] [PDF]

L. E. Littlepage and J. V. Ruderman
Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit
Genes & Dev., September 1, 2002; 16(17): 2274 - 2285.
[Abstract] [Full Text] [PDF]

T. A. Kufer, H. H.W. Sillje, R. Korner, O. J. Gruss, P. Meraldi, and E. A. Nigg
Human TPX2 is required for targeting Aurora-A kinase to the spindle
J. Cell Biol., August 19, 2002; 158(4): 617 - 623.
[Abstract] [Full Text] [PDF]

J. D. Bishop and J. M. Schumacher
Phosphorylation of the Carboxyl Terminus of Inner Centromere Protein (INCENP) by the Aurora B Kinase Stimulates Aurora B Kinase Activity
J. Biol. Chem., July 26, 2002; 277(31): 27577 - 27580.
[Abstract] [Full Text] [PDF]

M. Tanaka, A. Ueda, H. Kanamori, H. Ideguchi, J. Yang, S. Kitajima, and Y. Ishigatsubo
Cell-cycle-dependent Regulation of Human aurora A Transcription Is Mediated by Periodic Repression of E4TF1
J. Biol. Chem., March 15, 2002; 277(12): 10719 - 10726.
[Abstract] [Full Text] [PDF]

J. Petersen, J. Paris, M. Willer, M. Philippe, and I. M. Hagan
The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation
J. Cell Sci., March 14, 2002; 114(24): 4371 - 4384.
[Abstract] [Full Text] [PDF]

R. Giet, D. McLean, S. Descamps, M. J. Lee, J. W. Raff, C. Prigent, and D. M. Glover
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
J. Cell Biol., February 4, 2002; 156(3): 437 - 451.
[Abstract] [Full Text] [PDF]

C. Crosio, G. M. Fimia, R. Loury, M. Kimura, Y. Okano, H. Zhou, S. Sen, C. D. Allis, and P. Sassone-Corsi
Mitotic Phosphorylation of Histone H3: Spatio-Temporal Regulation by Mammalian Aurora Kinases
Mol. Cell. Biol., February 1, 2002; 22(3): 874 - 885.
[Abstract] [Full Text] [PDF]

H. Katayama, H. Zhou, Q. Li, M. Tatsuka, and S. Sen
Interaction and Feedback Regulation between STK15/BTAK/Aurora-A Kinase and Protein Phosphatase 1 through Mitotic Cell Division Cycle
J. Biol. Chem., November 30, 2001; 276(49): 46219 - 46224.
[Abstract] [Full Text] [PDF]

R. Giet and D. M. Glover
Drosophila Aurora B Kinase Is Required for Histone H3 Phosphorylation and Condensin Recruitment during Chromosome Condensation and to Organize the Central Spindle during Cytokinesis
J. Cell Biol., February 12, 2001; 152(4): 669 - 682.
[Abstract] [Full Text] [PDF]

A. Kawasaki, I. Matsumura, J.-i. Miyagawa, S. Ezoe, H. Tanaka, Y. Terada, M. Tatsuka, T. Machii, H. Miyazaki, Y. Furukawa, et al.
Downregulation of an AIM-1 Kinase Couples with Megakaryocytic Polyploidization of Human Hematopoietic Cells
J. Cell Biol., January 16, 2001; 152(2): 275 - 288.
[Abstract] [Full Text] [PDF]

R. Giet and C. Prigent
The non-catalytic domain of the Xenopus laevis auroraA kinase localises the protein to the centrosome
J. Cell Sci., January 6, 2001; 114(11): 2095 - 2104.
[Abstract] [Full Text] [PDF]

H Nakamura, C Wu, J Kuang, C Larabell, and L. Etkin
XCS-1, a maternally expressed gene product involved in regulating mitosis in Xenopus
J. Cell Sci., January 7, 2000; 113(13): 2497 - 2505.
[Abstract] [PDF]

M Frank-Vaillant, O Haccard, C Thibier, R Ozon, Y Arlot-Bonnemains, C Prigent, and C Jessus
Progesterone regulates the accumulation and the activation of Eg2 kinase in Xenopus oocytes
J. Cell Sci., January 4, 2000; 113(7): 1127 - 1138.
[Abstract] [PDF]

W. Zachariae and K. Nasmyth
Whose end is destruction: cell division and the anaphase-promoting complex
Genes & Dev., August 15, 1999; 13(16): 2039 - 2058.
[Full Text]

				L. Sun, R. Hodeify, S. Haun, A. Charlesworth, A. M. MacNicol, S. Ponnappan, U. Ponnappan, C. Prigent, and K. Machaca Ca2+ Homeostasis Regulates Xenopus Oocyte Maturation Biol Reprod, April 1, 2008; 78(4): 726 - 735. [Abstract] [Full Text] [PDF]

				X.-F. Huang, S.-K. Luo, J. Xu, J. Li, D.-R. Xu, L.-H. Wang, M. Yan, X.-R. Wang, X.-B. Wan, F.-M. Zheng, et al. Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia Blood, March 1, 2008; 111(5): 2854 - 2865. [Abstract] [Full Text] [PDF]

				S. Uzbekova, Y. Arlot-Bonnemains, J. Dupont, R. Dalbies-Tran, P. Papillier, S. Pennetier, A. Thelie, C. Perreau, P. Mermillod, C. Prigent, et al. Spatio-Temporal Expression Patterns of Aurora Kinases A, B, and C and Cytoplasmic Polyadenylation-Element-Binding Protein in Bovine Oocytes During Meiotic Maturation Biol Reprod, February 1, 2008; 78(2): 218 - 233. [Abstract] [Full Text] [PDF]

				M. Venoux, J. Basbous, C. Berthenet, C. Prigent, A. Fernandez, N. J. Lamb, and S. Rouquier ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis Hum. Mol. Genet., January 15, 2008; 17(2): 215 - 224. [Abstract] [Full Text] [PDF]

				J. T. Irelan, T. J. Murphy, P. D. DeJesus, H. Teo, D. Xu, M. A. Gomez-Ferreria, Y. Zhou, L. J. Miraglia, D. R. Rines, I. M. Verma, et al. A role for I{kappa}B kinase 2 in bipolar spindle assembly PNAS, October 23, 2007; 104(43): 16940 - 16945. [Abstract] [Full Text] [PDF]

				A. R. Barr and F. Gergely Aurora-A: the maker and breaker of spindle poles J. Cell Sci., September 1, 2007; 120(17): 2987 - 2996. [Abstract] [Full Text] [PDF]

				M. G. Manfredi, J. A. Ecsedy, K. A. Meetze, S. K. Balani, O. Burenkova, W. Chen, K. M. Galvin, K. M. Hoar, J. J. Huck, P. J. LeRoy, et al. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase PNAS, March 6, 2007; 104(10): 4106 - 4111. [Abstract] [Full Text] [PDF]

				J. Fu, M. Bian, Q. Jiang, and C. Zhang Roles of Aurora Kinases in Mitosis and Tumorigenesis Mol. Cancer Res., January 1, 2007; 5(1): 1 - 10. [Abstract] [Full Text] [PDF]

				Q. Liu and J. V. Ruderman Aurora A, mitotic entry, and spindle bipolarity PNAS, April 11, 2006; 103(15): 5811 - 5816. [Abstract] [Full Text] [PDF]

				A. Graindorge, R. Thuret, N. Pollet, H. B. Osborne, and Y. Audic Identification of post-transcriptionally regulated Xenopus tropicalis maternal mRNAs by microarray Nucleic Acids Res., February 7, 2006; 34(3): 986 - 995. [Abstract] [Full Text] [PDF]

				T. Fukuda, Y. Mishina, M. P. Walker, and R. P. DiAugustine Conditional Transgenic System for Mouse Aurora A Kinase: Degradation by the Ubiquitin Proteasome Pathway Controls the Level of the Transgenic Protein Mol. Cell. Biol., June 15, 2005; 25(12): 5270 - 5281. [Abstract] [Full Text] [PDF]

				G. Pascreau, J.-G. Delcros, J.-Y. Cremet, C. Prigent, and Y. Arlot-Bonnemains Phosphorylation of Maskin by Aurora-A Participates in the Control of Sequential Protein Synthesis during Xenopus laevis Oocyte Maturation J. Biol. Chem., April 8, 2005; 280(14): 13415 - 13423. [Abstract] [Full Text] [PDF]

				R. Crane, A. Kloepfer, and J. V. Ruderman Requirements for the destruction of human Aurora-A J. Cell Sci., December 1, 2004; 117(25): 5975 - 5983. [Abstract] [Full Text] [PDF]

				S. Brunet, T. Sardon, T. Zimmerman, T. Wittmann, R. Pepperkok, E. Karsenti, and I. Vernos Characterization of the TPX2 Domains Involved in Microtubule Nucleation and Spindle Assembly in Xenopus Egg Extracts Mol. Biol. Cell, December 1, 2004; 15(12): 5318 - 5328. [Abstract] [Full Text] [PDF]

				M. Ouchi, N. Fujiuchi, K. Sasai, H. Katayama, Y. A. Minamishima, P. P. Ongusaha, C. Deng, S. Sen, S. W. Lee, and T. Ouchi BRCA1 Phosphorylation by Aurora-A in the Regulation of G2 to M Transition J. Biol. Chem., May 7, 2004; 279(19): 19643 - 19648. [Abstract] [Full Text] [PDF]

				S. Kinoshita, N. Sueyoshi, H. Shoju, I. Suetake, M. Nakamura, S. Tajima, and I. Kameshita Cloning and Characterization of a Novel Ca2+/Calmodulin-Dependent Protein Kinase I Homologue in Xenopus laevis J. Biochem., May 1, 2004; 135(5): 619 - 630. [Abstract] [Full Text] [PDF]

				L.-J. Yao, Z.-S. Zhong, L.-S. Zhang, D.-Y. Chen, H. Schatten, and Q.-Y. Sun Aurora-A Is a Critical Regulator of Microtubule Assembly and Nuclear Activity in Mouse Oocytes, Fertilized Eggs, and Early Embryos Biol Reprod, May 1, 2004; 70(5): 1392 - 1399. [Abstract] [Full Text] [PDF]

				P. A. Eyers and J. L. Maller Regulation of Xenopus Aurora A Activation by TPX2 J. Biol. Chem., March 5, 2004; 279(10): 9008 - 9015. [Abstract] [Full Text] [PDF]

				T. Marumoto, S. Honda, T. Hara, M. Nitta, T. Hirota, E. Kohmura, and H. Saya Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells J. Biol. Chem., December 19, 2003; 278(51): 51786 - 51795. [Abstract] [Full Text] [PDF]

				N. Trieselmann, S. Armstrong, J. Rauw, and A. Wilde Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation J. Cell Sci., December 1, 2003; 116(23): 4791 - 4798. [Abstract] [Full Text] [PDF]

				Y. Terada, Y. Uetake, and R. Kuriyama Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells J. Cell Biol., September 1, 2003; 162(5): 757 - 764. [Abstract] [Full Text] [PDF]

				E. Watrin, F. Cubizolles, H. B. Osborne, K. Le Guellec, and V. Legagneux Expression and Functional Dynamics of the XCAP-D2 Condensin Subunit in Xenopus laevis Oocytes J. Biol. Chem., July 3, 2003; 278(28): 25708 - 25715. [Abstract] [Full Text] [PDF]

				G. Maton, C. Thibier, A. Castro, T. Lorca, C. Prigent, and C. Jessus Cdc2-Cyclin B Triggers H3 Kinase Activation of Aurora-A in Xenopus Oocytes J. Biol. Chem., June 6, 2003; 278(24): 21439 - 21449. [Abstract] [Full Text] [PDF]

				S. L. Warner, D. J. Bearss, H. Han, and D. D. Von Hoff Targeting Aurora-2 Kinase in Cancer Mol. Cancer Ther., June 1, 2003; 2(6): 589 - 595. [Abstract] [Full Text] [PDF]

				A. Kawajiri, Y. Yasui, H. Goto, M. Tatsuka, M. Takahashi, K.-i. Nagata, and M. Inagaki Functional Significance of the Specific Sites Phosphorylated in Desmin at Cleavage Furrow: Aurora-B May Phosphorylate and Regulate Type III Intermediate Filaments during Cytokinesis Coordinatedly with Rho-kinase Mol. Biol. Cell, April 1, 2003; 14(4): 1489 - 1500. [Abstract] [Full Text] [PDF]

				C. Ma, C. Cummings, and X. J. Liu Biphasic Activation of Aurora-A Kinase during the Meiosis I- Meiosis II Transition in Xenopus Oocytes Mol. Cell. Biol., March 1, 2003; 23(5): 1703 - 1716. [Abstract] [Full Text] [PDF]

				A. Castro, E. Mandart, T. Lorca, and S. Galas Involvement of Aurora A Kinase during Meiosis I-II Transition in Xenopus Oocytes J. Biol. Chem., January 17, 2003; 278(4): 2236 - 2241. [Abstract] [Full Text] [PDF]

				H. Sakai, T. Urano, K. Ookata, M.-H. Kim, Y. Hirai, M. Saito, Y. Nojima, and F. Ishikawa MBD3 and HDAC1, Two Components of the NuRD Complex, Are Localized at Aurora-A-positive Centrosomes in M Phase J. Biol. Chem., December 6, 2002; 277(50): 48714 - 48723. [Abstract] [Full Text] [PDF]

				L. E. Littlepage, H. Wu, T. Andresson, J. K. Deanehan, L. T. Amundadottir, and J. V. Ruderman Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A PNAS, November 26, 2002; 99(24): 15440 - 15445. [Abstract] [Full Text] [PDF]

				L. E. Littlepage and J. V. Ruderman Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit Genes & Dev., September 1, 2002; 16(17): 2274 - 2285. [Abstract] [Full Text] [PDF]