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Auerbach, R., Auerbach, W. and Polakowski, I (1991). Assays for angiogenesis: A review. Pharmac. Ther 51, 1-11.

Barone, M. V. and Courtneidge, S. A (1995). Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src. Nature 378, 509-512.[Medline]

Bazenet, C. E., Gelderloos, J. A. and Kazlauskas, A (1996). Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation. Mol. Cell Biol 16, 6926-6936.[Abstract]

Bostr\232m, H., Willetts, K., Pekny, M., Leveen, P., Lindahl, P., Hedstrand, H., Pekna, M., Hellstr\232m, M., Gebre-Medhin, S., Schalling, M., Nilsson, M., Kurland, S., T\232rnell, J., Heath, J. K. and Betsholtz, C (1996). PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell 85, 863-873.[Medline]

Kapeller, R. and Soltoff, S (1991). Oncogenes and signal transduction. Cell 64, 281-302.[Medline]

Claesson-Welsh, L., Eriksson, A., Moren, A., Severinsson, L., Ek, B., \205stman, A., Betsholtz, C. and Heldin, C.-H (1988). cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules. Mol. Cell. Biol 8, 3476-3486.[Abstract/Free Full Text]

Claesson-Welsh, L., Eriksson, A., Westermark, B. and Heldin, C.-H (1989). cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor. Proc. Nat. Acad. Sci. USA 86, 4917-4921.[Abstract/Free Full Text]

Claesson-Welsh, L (1994). Platelet-derived growth factor receptor signals. J. Biol. Chem 269, 32023-32026.[Free Full Text]

Egan, S. E., Giddings, B. W., Brooks, M. W., Buday, L., Sizeland, A. M. and Weinberg, R. A (1993). Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363, 45-51.[Medline]

Eisenman, R. N. and Cooper, J. A (1995). Beating a path to Myc. Nature 378, 438-439.[Medline]

Eriksson, A., N\214nberg, E., R\232nnstrand, L., Engstr\232m, U., Hellman, U., Rupp, E., Carpenter, G., Heldin, C.-H. and Claesson-Welsh, L (1995). Demonstration of functionally different interactions between phospholipase C-and the two types of platelet-derived growth factor receptors. J. Biol. Chem 270, 7773-7781.[Abstract/Free Full Text]

Eriksson, A., Siegbahn, A., Westermark, B., Heldin, C.-H. and Claesson-Welsh, L (1992). PDGF-and -receptors activate unique and common signal transduction pathways. EMBO J 11, 543-550.[Medline]

Heldin, C.-H., B\212ckstr\232m, G., \205stman, A., Hammacher, A., R\232nnstrand, L., Rubin, K., Nister, M. and Westermark, B (1988). Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types. EMBO J 7, 1387-1393.[Medline]

Kypta, R. M., Goldberg, Y., Ulug, E. T. and Courtneidge, S. A (1990). Association between the PDGF receptor and members of the src family of tyrosine kinases. Cell 62, 481-492.[Medline]

Leveen, P., Pekny, M., Gebre-Medhin, S., Swolin, B., Larsson, E. and Betsholtz, C (1994). Mice deficient for PDGF B show renal, cardiovascular and hematological abnormalities. Genes Dev 8, 1875-1887.[Abstract/Free Full Text]

Liao, F., Shin, H. S. and Rhee, S. G (1993). In vitro tyrosine phosphorylation of PLC-1 and PLC- 2 by src-family protein tyrosine kinases. Biochem. Biophys. Res. Commun 191, 1028-1033.[Medline]

Marais, R., Light, Y., Paterson, H. F. and Marshall, C. J (1995). Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. EMBO J 14, 3136-3145.[Medline]

Matsui, T., Heidaran, M., Miki, T., Toru, M., Popescu, N., La Rochelle, W., Kraus, M., Pierce, J. and Aaronson, S. A (1989). Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science 243, 800-803.[Abstract/Free Full Text]

McGlade, J., Cheng, A., Pelicci, G., Pelicci, P. G. and Pawson, T (1992). Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases. Proc. Nat. Acad. Sci. USA 89, 8869-8873.[Abstract/Free Full Text]

Miyazono, K., Okabe, T., Urabe, A., Takaku, F. and Heldin, C.-H (1987). Purification and properties of an endothelial cell growth factor from human platelets. J. Biol. Chem 262, 4098-4103.[Abstract/Free Full Text]

Mori, S., R\232nnstrand, L., Yokote, K., Engstr\232m, \201., Courtneidge, S. A., Claesson-Welsh, L. and Heldin, C.-H (1993). Identification of two juxtamembrane autophosphorylation sites in the PDGF-receptor; involvement in the interaction with Src family tyrosine kinases. EMBO J 12, 2257-2264.[Medline]

Nada, S., Okada, M., Aizawa, S. and Nakagawa, H (1994). Identification of major tyrosine-phosphorylated proteins in Csk-deficient cells. Oncogene 9, 3571-3578.[Medline]

Nakanishi, O., Shibasaki, F., Hidaka, M., Homma, Y. and Takenawa, T (1993). Phospholipase C-1 associates with viral and cellular src kinases. J. Biol. Chem 268, 10754-10759.[Abstract/Free Full Text]

Okada, M., Nada, S., Yamanashi, Y., Yamamoto, T. and Nakagawa, H (1991). CSK: a protein-tyrosine kinase involved in regulation of src family kinases. J. Biol. Chem 266, 24249-24252.[Abstract/Free Full Text]

Pawson, T (1995). Protein modules and signalling networks. Nature 373, 573-580.[Medline]

Rupp, E., Siegbahn, A., R\232nnstrand, L., Wernstedt, C., Claesson-Welsh, L. and Heldin, C.-H (1994). A unique autophosphorylation site in the platelet-derived growth factorreceptor from a heterodimeric receptor complex. Eur. J. Biochem 225, 29-41.[Medline]

R\232nnstrand, L., Mori, S., Arvidsson, A.-K., Eriksson, A., Wernstedt, C., Hellman, U., Claesson-Welsh, L. and Heldin, C.-H (1992). Identification of two C-terminal autophosphorylation sites in the PDGF-receptor: involvement in the interaction with phospholipase C-. EMBO J 11, 3911-3919.[Medline]

Smith, M. R., DeGudicubus, S. J. and Stacey, D. W (1986). Requirement for c-ras proteins during viral oncogene transformation. Nature 320, 540-543.[Medline]

Soriano, P (1994). Abnormal kidney development and hematological disorders in PDGF-receptor mutant mice. Genes Dev 8, 1888-1896.[Abstract/Free Full Text]

Soriano, P (1997). The PDGFreceptor is required for neural crest cell development and for normal patterning of the somites. Development 124, 2691-2700.[Abstract]

Stokoe, D. and McCormick, F (1997). Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro. EMBO J 16, 2384-2396.[Medline]

Twamley-Stein, G. M., Pepperkok, R., Ansorge, W. and Courtneidge, S. A (1993). The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells. Proc. Nat. Acad. Sci. USA 90, 7696-7700.[Abstract/Free Full Text]

Ullrich, A. and Schlessinger, J (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.[Medline]

Vaillancourt, R. R., Heasley, L. E., Zamarripa, J., Storey, B., Valius, M., Kazlauskas, A. and Johnson, G. L (1995). Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation. Mol. Cell. Biol 15, 3644-3653.[Abstract]

Wennstr\232m, S., Landgren, E., Blume-Jensen, P. and Claesson-Welsh, L (1992). The platelet-derived growth factor-receptor kinase insert confers specific signaling properties to a chimeric fibroblast growth factor receptor. J. Biol. Chem 267, 13749-13756.[Abstract/Free Full Text]

Wennstr\232m, S., Siegbahn, A., Yokote, K., Arvidsson, A.-K., Heldin, C.-H., Mori, S. and Claesson-Welsh, L (1994). Membrane ruffling and chemotaxis transduced by the PDGF-receptor require the binding site for phosphatidylinositol 3 kinase. Oncogene 9, 651-660.[Medline]

Yarden, Y., Escobedo, J. A., Kuang, W.-J., Yang-Feng, T. L., Daniel, T. O., Tremble, P. M., Chen, E. Y., Ando, M. E., Harkins, R. N., Francke, U., Friend, V. A., Ullrich, A. and Williams, L. T (1986). Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature 323, 226-232.[Medline]

Yokote, K., Mori, S., Siegbahn, A., R\232nnstrand, L., Wernstedt, C., Heldin, C.-H. and Claesson-Welsh, L (1996). Structural determinants in the platelet-derived growth factor-receptor implicated in modulation of chemotaxis. J. Biol. Chem 271, 5101-5111.[Abstract/Free Full Text]

Yu, J.-C., Heidaran, M. A., Pierce, J. H., Gutkind, J. S., Lombardi, D., Ruggiero, M. and Aaronson, S. A (1991). Tyrosine mutations within theplatelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction. Mol. Cell. Biol 11, 3780-3785.[Abstract/Free Full Text]


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