A novel signal transduction cascade in capacitating human spermatozoa characterised by a redox-regulated, cAMP-mediated induction of tyrosine phosphorylation

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				C. Lawson, S. Goupil, and P. Leclerc Increased Activity of the Human Sperm Tyrosine Kinase SRC by the cAMP-Dependent Pathway in the Presence of Calcium Biol Reprod, October 1, 2008; 79(4): 657 - 666. [Abstract] [Full Text] [PDF]

				L. A. Mitchell, B. Nixon, M. A. Baker, and R. J. Aitken Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa Mol. Hum. Reprod., April 1, 2008; 14(4): 235 - 243. [Abstract] [Full Text] [PDF]

				K Sabeur and B A Ball Characterization of NADPH oxidase 5 in equine testis and spermatozoa Reproduction, August 1, 2007; 134(2): 263 - 270. [Abstract] [Full Text] [PDF]

				P. Grasa, J. A. Cebrian-Perez, and T. Muino-Blanco Signal transduction mechanisms involved in in vitro ram sperm capacitation. Reproduction, November 1, 2006; 132(5): 721 - 732. [Abstract] [Full Text] [PDF]

				M. Lin, Y. H. Lee, W. Xu, M. A. Baker, and R. J. Aitken Ontogeny of Tyrosine Phosphorylation-Signaling Pathways During Spermatogenesis and Epididymal Maturation in the Mouse Biol Reprod, October 1, 2006; 75(4): 588 - 597. [Abstract] [Full Text] [PDF]

				M. A. Baker, L. Hetherington, and R. J. Aitken Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa J. Cell Sci., August 1, 2006; 119(15): 3182 - 3192. [Abstract] [Full Text] [PDF]

				J. Baumber and S. A. Meyers Changes in Membrane Lipid Order With Capacitation in Rhesus Macaque (Macaca mulatta) Spermatozoa J Androl, July 1, 2006; 27(4): 578 - 587. [Abstract] [Full Text] [PDF]

				M. T. Branham, L. S. Mayorga, and C. N. Tomes Calcium-induced Acrosomal Exocytosis Requires cAMP Acting through a Protein Kinase A-independent, Epac-mediated Pathway J. Biol. Chem., March 31, 2006; 281(13): 8656 - 8666. [Abstract] [Full Text] [PDF]

				B. Nixon, J. W. Paul, C. M. Spiller, A. G. Attwell-Heap, L. K. Ashman, and R. J. Aitken Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa J. Cell Sci., October 15, 2005; 118(20): 4865 - 4877. [Abstract] [Full Text] [PDF]

				M. A. Baker, A. Krutskikh, B. J. Curry, L. Hetherington, and R. J. Aitken Identification of Cytochrome-b5 Reductase as the Enzyme Responsible for NADH-Dependent Lucigenin Chemiluminescence in Human Spermatozoa Biol Reprod, August 1, 2005; 73(2): 334 - 342. [Abstract] [Full Text] [PDF]

				F.L.C. Moseley, K.N. Jha, L. Bjorndahl, I.A. Brewis, S.J. Publicover, C.L.R. Barratt, and L. Lefievre Protein tyrosine phosphorylation, hyperactivation and progesterone-induced acrosome reaction are enhanced in IVF media: an effect that is not associated with an increase in protein kinase A activation Mol. Hum. Reprod., July 1, 2005; 11(7): 523 - 529. [Abstract] [Full Text] [PDF]

				C. O'Flaherty, E. de Lamirande, and C. Gagnon Reactive Oxygen Species and Protein Kinases Modulate the Level of Phospho-MEK-Like Proteins During Human Sperm Capacitation Biol Reprod, July 1, 2005; 73(1): 94 - 105. [Abstract] [Full Text] [PDF]

				M. G Buffone, J. C Calamera, S. V Verstraeten, and G. F Doncel Capacitation-associated protein tyrosine phosphorylation and membrane fluidity changes are impaired in the spermatozoa of asthenozoospermic patients Reproduction, June 1, 2005; 129(6): 697 - 705. [Abstract] [Full Text] [PDF]

				M. Luconi, I. Porazzi, P. Ferruzzi, S. Marchiani, G. Forti, and E. Baldi Tyrosine Phosphorylation of the A Kinase Anchoring Protein 3 (AKAP3) and Soluble Adenylate Cyclase Are Involved in the Increase of Human Sperm Motility by Bicarbonate Biol Reprod, January 1, 2005; 72(1): 22 - 32. [Abstract] [Full Text] [PDF]

				W.C.L. Ford Regulation of sperm function by reactive oxygen species Hum. Reprod. Update, September 1, 2004; 10(5): 387 - 399. [Abstract] [Full Text] [PDF]

				K. L. Asquith, R. M. Baleato, E. A. McLaughlin, B. Nixon, and R. J. Aitken Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition J. Cell Sci., July 15, 2004; 117(16): 3645 - 3657. [Abstract] [Full Text] [PDF]

				K. Mitra and S. Shivaji Novel Tyrosine-Phosphorylated Post-Pyruvate Metabolic Enzyme, Dihydrolipoamide Dehydrogenase, Involved in Capacitation of Hamster Spermatozoa Biol Reprod, April 1, 2004; 70(4): 887 - 899. [Abstract] [Full Text] [PDF]

				A. Minelli, L. Liguori, I. Bellazza, R. Mannucci, B. Johansson, and B. B. Fredholm Involvement of A1 Adenosine Receptors in the Acquisition of Fertilizing Capacity J Androl, March 1, 2004; 25(2): 286 - 292. [Abstract] [Full Text] [PDF]

				C. Rodeheffer and B. D. Shur Sperm from {beta}1,4-galactosyltransferase I-null mice exhibit precocious capacitation Development, February 1, 2004; 131(3): 491 - 501. [Abstract] [Full Text] [PDF]

				J. Rivlin, J. Mendel, S. Rubinstein, N. Etkovitz, and H. Breitbart Role of Hydrogen Peroxide in Sperm Capacitation and Acrosome Reaction Biol Reprod, February 1, 2004; 70(2): 518 - 522. [Abstract] [Full Text] [PDF]

				M. A. Baker, L. Hetherington, H. Ecroyd, S. D. Roman, and R. J. Aitken Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation J. Cell Sci., January 15, 2004; 117(2): 211 - 222. [Abstract] [Full Text] [PDF]

				M.G. Buffone, G.F. Doncel, C.I. Marin Briggiler, M.H. Vazquez-Levin, and J.C. Calamera Human sperm subpopulations: relationship between functional quality and protein tyrosine phosphorylation Hum. Reprod., January 1, 2004; 19(1): 139 - 146. [Abstract] [Full Text] [PDF]

				K S Sidhu, K E Mate, T Gunasekera, D Veal, L Hetherington, M A Baker, R J Aitken, and J C Rodger A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula) Reproduction, January 1, 2004; 127(1): 95 - 103. [Abstract] [Full Text] [PDF]

				H. Ecroyd, R. C. Jones, and R. J. Aitken Tyrosine Phosphorylation of HSP-90 During Mammalian Sperm Capacitation Biol Reprod, December 1, 2003; 69(6): 1801 - 1807. [Abstract] [Full Text] [PDF]

				R.J. Aitken, A.L. Ryan, B.J. Curry, and M.A. Baker Multiple forms of redox activity in populations of human spermatozoa Mol. Hum. Reprod., November 1, 2003; 9(11): 645 - 661. [Abstract] [Full Text] [PDF]

				H. Harayama Viability and Protein Phosphorylation Patterns of Boar Spermatozoa Agglutinated by Treatment With a Cell-Permeable Cyclic Adenosine 3',5'-Monophosphate Analog J Androl, November 1, 2003; 24(6): 831 - 842. [Abstract] [Full Text] [PDF]

				N. L. Cross Decrease in Order of Human Sperm Lipids During Capacitation Biol Reprod, August 1, 2003; 69(2): 529 - 534. [Abstract] [Full Text] [PDF]

				J. Baumber, B. A. Ball, J. J. Linfor, and S. A. Meyers Reactive Oxygen Species and Cryopreservation Promote DNA Fragmentation in Equine Spermatozoa J Androl, July 1, 2003; 24(4): 621 - 628. [Abstract] [Full Text] [PDF]

				H. W. Ecroyd, R. C. Jones, and R. J. Aitken Endogenous Redox Activity in Mouse Spermatozoa and Its Role in Regulating the Tyrosine Phosphorylation Events Associated with Sperm Capacitation Biol Reprod, July 1, 2003; 69(1): 347 - 354. [Abstract] [Full Text] [PDF]

				M. R. Nimmo and N. L. Cross Structural Features of Sterols Required to Inhibit Human Sperm Capacitation Biol Reprod, April 1, 2003; 68(4): 1308 - 1317. [Abstract] [Full Text] [PDF]