Aberrant intracellular targeting and cell cycle-dependent phosphorylation of emerin contribute to the Emery-Dreifuss muscular dystrophy phenotype

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Bione, S., Maestrini, E., Rivella, S., Mancini, M., Regis, S., Romeo, G. and Toniolo, D (1994). Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy. Nature Genetics 8, 323-327.[Medline]

Bione, S., Small, K., Aksmanovic, V. M. A., D'Urso, M., Ciccodicola, A., Merlini, L., Morandi, L., Kress, W., Yates, J. R. W., Warren, S. T. and Toniolo, D (1995). Identification of new mutations in the Emery-Dreifuss muscular dystrophy gene and evidence for genetic heterogeneity of the disease. Hum. Mol. Gen 4, 1859-1863.[Abstract/Free Full Text]

Bradford, M. M (1976). A rapid and sensitive method for the quantificationof micrograms of protein utilizing the principle of protein-dye binding. Anal. Biochem 72, 248-254.[Medline]

Burnette, W. N (1981). \324Western blotting': electrophoretic transfer of proteins from SDS-PAGE gels to unmodified nitrocellulose and radiographic detection with antibodies and radioiodinated protein A. Anal. Biochem 112, 195-303.[Medline]

Cartegni, L., Raffaele di Barletta, M., Barresi, R., Squarzoni, S., Sabatelli, P., Maraldi, N., Mora, M., Di Blasi, C., Cornelio, F., Merlini, L., Villa, A., Cobianchi, F. and Toniolo, D (1997). Heart-specific localization of emerin: new insights into EDMD. Hum. Mol. Gen 6, 2257-2264.[Abstract/Free Full Text]

Craxton, M. and Goedert, M (1995). Synaptotagmin V: a novel synaptotagmin isoform expressed in rat brain. FEBS Lett 361, 196-200.[Medline]

Ellis, J. A., Jackman, M. R. and Luzio, J. P (1992). The post-synthetic sorting of endogenous membrane proteins examined by simultaneous purification of apical and basolateral plasma membrane fractions from Caco-2 cells. Biochem. J 283, 553-560.

Ellis, J. A. and Luzio, J. P (1995). Identification and characterization of a novel protein (p137), which transcytoses bidirectionally in Caco-2 cells. J. Biol. Chem 270, 20717-20723.[Abstract/Free Full Text]

Emery, A. E. H. and Dreifuss, F. E (1966). Unusual type of benign X-linked muscular dystrophy. J. Neurol. Neurosurg. Psychiat 29, 338-342.[Free Full Text]

Emery, A. E. H (1989). Emery-Dreifuss syndrome. J. Med. Gen 26, 637-642.[Abstract/Free Full Text]

Foisner, R. and Gerace, L (1993). Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation. Cell 73, 1267-1279.[Medline]

Furukawa, K., Pante, N., Aebi, U. and Gerace, L (1995). Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope. EMBO J 14, 1626-1636.[Medline]

Jackson, M. R., Nilsson, T. and Peterson, P. A (1990). Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum. EMBO. J 9, 3153-.[Medline]

Klauck, S. M., Wilgenbus, P., Yates, J. R. W., Muller, C. R. and Poustka, A (1995). Identification of novel mutations in three families with Emery-Dreifuss muscular dystrophy. Hum. Mol. Gen 4, 1853-1857.[Free Full Text]

Kutay, U., Ahnert-Hilger, G., Hartmann, E., Wiedenmann, B. and Rapoport, T. A (1995). Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane. EMBO. J 14, 217-223.[Medline]

Laemmli, U. K (1970). Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227, 680-685.[Medline]

Litchfield, D. W., Luscher, B., Lozeman, F. J., Eiseman, R. N. and Krebs, E. G (1992). Phosphorylation of casein kinase II by p34cdc2In vitro and at mitosis. J. Biol. Chem 267, 13943-13951.[Abstract/Free Full Text]

Lorenz, P., Pepperkok, R., Ansorge, W. and Pyerin, W (1993). Cell biological studies with monoclonal antibodies and polyclonal antibodies aginst human casein kinase II subunitdemonstrate participation of the kinase in mitogenic signalling. J. Biol. Chem 268, 2733-2739.[Abstract/Free Full Text]

Manilal, S., Nguyen thi Man, Sewry, C. A. and Morris, G. E (1996). The Emery-Dreifuss muscular dystrophy protein, emerin, is a nuclear protein. Hum. Mol. Gen 5, 801-808.[Abstract/Free Full Text]

Mauxion, F., Le Borgne, R., Munier-Lehmann, H. and Hoflack, B (1996). A casein kinase II phosphorylation site in the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor determines the high affinity interaction of the AP-1 Golgi assembly proteins with membranes. J. Biol. Chem 271, 2171-22178.[Abstract/Free Full Text]

Nagano, A., Koga, R., Ogawa, M., Kurano, Y., Kawada, J., Okado, R., Hayashi, Y. K., Tsukahara, T. and Arahata, K (1996). Emerin deficiencyat the nuclear membrane in patients with Emery-Dreifuss muscular dystrophy. Nature Genetics 2, 254-259.

Nikolakaki, E., Simos, G., Georgatos, S. D. and Giannakouros, T (1996). A nuclear envelope-associated kinase phosphorylates arginine-serine motifs and modulates interactions between the lamin B receptor and other nuclear proteins. J. Biol. Chem 271, 8365-8372.[Abstract/Free Full Text]

Pelham, H. R. B. and Munro, S (1993). Sorting of membrane proteins in the secretory pathway. Cell 75, 603-605.[Medline]

Pepperkok, R., Lorenz, P. Ansorge, W. and Pyerin, W (1994). Casein kinase II is required for transition of G0/G1and G1/S phases of the cell cycle. J. Biol. Chem 269, 6986-6991.[Abstract/Free Full Text]

Soulham, B. and Worman, H. J (1995). Signals and structural features involved in integral membrane protein targeting to the inner nuclear membrane. J. Cell. Biol 130, 15-27.[Abstract/Free Full Text]

Vancurova, I., Jochova-Rupes, J., Lou, W. and Paine, P. L (1995). Distinct phosphorylation sites differentially influence facilitated transport of an NLS-protein and its subsequent intranuclear binding. Biochem. Biophys. Res. Commun 217, 419-427.[Medline]

Weinberg, R. A (1995). The Rb protein and cell cycle control. Cell 81, 323-330.[Medline]

Worman, H. J., Evans, C. D. and Blobel, G (1990). The lamin B receptor of the nuclear envelope inner membrane: a polytopic protein with eight potential transmembrane domains. J. Cell Biol 111, 1535-1542.[Abstract/Free Full Text]

Yun, K. and Wold, B (1996). Skeletal muscle determination and differentiation: story of a core regulatory network and its context. Curr. Opin. Cell Biol 8, 877-889.[Medline]

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				J. M. Holaska Emerin and the Nuclear Lamina in Muscle and Cardiac Disease Circ. Res., July 3, 2008; 103(1): 16 - 23. [Abstract] [Full Text] [PDF]

				N. Leach, S. L. Bjerke, D. K. Christensen, J. M. Bouchard, F. Mou, R. Park, J. Baines, T. Haraguchi, and R. J. Roller Emerin Is Hyperphosphorylated and Redistributed in Herpes Simplex Virus Type 1-Infected Cells in a Manner Dependent on both UL34 and US3 J. Virol., October 1, 2007; 81(19): 10792 - 10803. [Abstract] [Full Text] [PDF]

				P. Muhlhausser and U. Kutay An in vitro nuclear disassembly system reveals a role for the RanGTPase system and microtubule-dependent steps in nuclear envelope breakdown J. Cell Biol., August 9, 2007; 178(4): 595 - 610. [Abstract] [Full Text] [PDF]

				J. B. Morris, H. Hofemeister, and P. O'Hare Herpes Simplex Virus Infection Induces Phosphorylation and Delocalization of Emerin, a Key Inner Nuclear Membrane Protein J. Virol., May 1, 2007; 81(9): 4429 - 4437. [Abstract] [Full Text] [PDF]

				A. C. Rowat, J. Lammerding, and J. H. Ipsen Mechanical Properties of the Cell Nucleus and the Effect of Emerin Deficiency Biophys. J., December 15, 2006; 91(12): 4649 - 4664. [Abstract] [Full Text] [PDF]

				G. S. Wilkie and E. C. Schirmer Guilt by Association: The Nuclear Envelope Proteome and Disease Mol. Cell. Proteomics, October 1, 2006; 5(10): 1865 - 1875. [Abstract] [Full Text] [PDF]

				F. Haque, D. J. Lloyd, D. T. Smallwood, C. L. Dent, C. M. Shanahan, A. M. Fry, R. C. Trembath, and S. Shackleton SUN1 Interacts with Nuclear Lamin A and Cytoplasmic Nesprins To Provide a Physical Connection between the Nuclear Lamina and the Cytoskeleton Mol. Cell. Biol., May 15, 2006; 26(10): 3738 - 3751. [Abstract] [Full Text] [PDF]

				L. Bengtsson and K. L. Wilson Barrier-to-Autointegration Factor Phosphorylation on Ser-4 Regulates Emerin Binding to Lamin A In Vitro and Emerin Localization In Vivo Mol. Biol. Cell, March 1, 2006; 17(3): 1154 - 1163. [Abstract] [Full Text] [PDF]

				Y. Hirano, M. Segawa, F. S. Ouchi, Y. Yamakawa, K. Furukawa, K. Takeyasu, and T. Horigome Dissociation of Emerin from Barrier-to-autointegration Factor Is Regulated through Mitotic Phosphorylation of Emerin in a Xenopus Egg Cell-free System J. Biol. Chem., December 2, 2005; 280(48): 39925 - 39933. [Abstract] [Full Text] [PDF]

				J. Lammerding, J. Hsiao, P. C. Schulze, S. Kozlov, C. L. Stewart, and R. T. Lee Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells J. Cell Biol., August 29, 2005; 170(5): 781 - 791. [Abstract] [Full Text] [PDF]

				H. Hofemeister and P. O'Hare Analysis of the Localization and Topology of Nurim, a Polytopic Protein Tightly Associated with the Inner Nuclear Membrane J. Biol. Chem., January 28, 2005; 280(4): 2512 - 2521. [Abstract] [Full Text] [PDF]

				S. Tulac, C. Dosiou, E. Suchanek, and L. C. Giudice Silencing lamin A/C in human endometrial stromal cells: a model to investigate endometrial gene function and regulation Mol. Hum. Reprod., October 1, 2004; 10(10): 705 - 711. [Abstract] [Full Text] [PDF]

				D. M. Hodzic, D. B. Yeater, L. Bengtsson, H. Otto, and P. D. Stahl Sun2 Is a Novel Mammalian Inner Nuclear Membrane Protein J. Biol. Chem., June 11, 2004; 279(24): 25805 - 25812. [Abstract] [Full Text] [PDF]

				J. M. Holaska, K. K. Lee, A. K. Kowalski, and K. L. Wilson Transcriptional Repressor Germ Cell-less (GCL) and Barrier to Autointegration Factor (BAF) Compete for Binding to Emerin in Vitro J. Biol. Chem., February 21, 2003; 278(9): 6969 - 6975. [Abstract] [Full Text] [PDF]

				C. Vigouroux, M. Auclair, E. Dubosclard, M. Pouchelet, J. Capeau, J.-C. Courvalin, and B. Buendia Nuclear envelope disorganization in fibroblasts from lipodystrophic patients with heterozygous R482Q/W mutations in the lamin A/C gene J. Cell Sci., March 14, 2002; 114(24): 4459 - 4468. [Abstract] [Full Text] [PDF]

				Q. Zhang, J. N. Skepper, F. Yang, J. D. Davies, L. Hegyi, R. G. Roberts, P. L. Weissberg, J. A. Ellis, and C. M. Shanahan Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues J. Cell Sci., March 14, 2002; 114(24): 4485 - 4498. [Abstract] [Full Text] [PDF]

				K. K. Lee, T. Haraguchi, R. S. Lee, T. Koujin, Y. Hiraoka, and K. L. Wilson Distinct functional domains in emerin bind lamin A and DNA-bridging protein BAF J. Cell Sci., March 14, 2002; 114(24): 4567 - 4573. [Abstract] [Full Text] [PDF]

				T. Haraguchi, T. Koujin, M. Segura-Totten, K. K. Lee, Y. Matsuoka, Y. Yoneda, K. L. Wilson, and Y. Hiraoka BAF is required for emerin assembly into the reforming nuclear envelope J. Cell Sci., March 14, 2002; 114(24): 4575 - 4585. [Abstract] [Full Text] [PDF]

				O. A. Vaughan, M. Alvarez-Reyes, J. M. Bridger, J. L. V. Broers, F. C. S. Ramaekers, M. Wehnert, G. E. Morris, W. G. F. Whitfield, and C. J. Hutchison Both emerin and lamin C depend on lamin A for localization at the nuclear envelope J. Cell Sci., March 9, 2002; 114(14): 2577 - 2590. [Abstract] [Full Text] [PDF]

				E. A. L. Fairley, A. Riddell, J. A. Ellis, and J. Kendrick-Jones The cell cycle dependent mislocalisation of emerin may contribute to the Emery-Dreifuss muscular dystrophy phenotype J. Cell Sci., January 15, 2002; 115(2): 341 - 354. [Abstract] [Full Text] [PDF]

				W. Wu, F. Lin, and H. J. Worman Intracellular trafficking of MAN1, an integral protein of the nuclear envelope inner membrane J. Cell Sci., January 4, 2002; 115(7): 1361 - 1371. [Abstract] [Full Text] [PDF]

				Y. Gruenbaum, K. K. Lee, J. Liu, M. Cohen, and K. L. Wilson The expression, lamin-dependent localization and RNAi depletion phenotype for emerin in C. elegans J. Cell Sci., January 3, 2002; 115(5): 923 - 929. [Abstract] [Full Text] [PDF]

				S. Boyle, S. Gilchrist, J. M. Bridger, N. L. Mahy, J. A. Ellis, and W. A. Bickmore The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells Hum. Mol. Genet., February 1, 2001; 10(3): 211 - 219. [Abstract] [Full Text] [PDF]

				J. Plenefisch, X Zhu, and E. Hedgecock Fragile skeletal muscle attachments in dystrophic mutants of Caenorhabditis elegans: isolation and characterization of the mua genes Development, January 3, 2000; 127(6): 1197 - 1207. [Abstract] [PDF]

				T. Sullivan, D. Escalante-Alcalde, H. Bhatt, M. Anver, N. Bhat, K. Nagashima, C. L. Stewart, and B. Burke Loss of A-type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy J. Cell Biol., November 29, 1999; 147(5): 913 - 920. [Abstract] [Full Text] [PDF]

				G. E. Morris and S. Manilal Heart to heart: from nuclearproteins to Emery-Dreifuss muscular dystrophy Hum. Mol. Genet., September 1, 1999; 8(10): 1847 - 1851. [Abstract] [Full Text] [PDF]

				M. M. Rolls, P. A. Stein, S. S. Taylor, E. Ha, F. McKeon, and T. A. Rapoport A Visual Screen of a GFP-fusion Library Identifies a New Type of Nuclear Envelope Membrane Protein J. Cell Biol., July 12, 1999; 146(1): 29 - 44. [Abstract] [Full Text] [PDF]

				E. Fairley, J Kendrick-Jones, and J. Ellis The Emery-Dreifuss muscular dystrophy phenotype arises from aberrant targeting and binding of emerin at the inner nuclear membrane J. Cell Sci., January 8, 1999; 112(15): 2571 - 2582. [Abstract] [PDF]

				C Ostlund, J Ellenberg, E Hallberg, J Lippincott-Schwartz, and H. Worman Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein J. Cell Sci., January 6, 1999; 112(11): 1709 - 1719. [Abstract] [PDF]