L-CAM expression induces fibroblast-epidermoid transition in squamous carcinoma cells and down-regulates the endogenous N-cadherin

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Li, Z.
	Articles by Pasdar, M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Li, Z.
	Articles by Pasdar, M.

Aberle, H., Schwartz, H. and Kemler, R (1996). Cadherin-catenin complex: protein interactions and their implications for cadherin function. J. Cell. Biochem 61, 514-523.[Medline]

Birchmeier, W (1995). E-cadherin as a tumor (invasion) suppressor gene. BioEssays 17, 97-99.[Medline]

Boyd, J. A. and Barrett, C (1990). Tumor suppressor genes: possible functions in negative regulation of cell proliferation. Molec. Carcinogen 3, 325-329.[Medline]

Brackenbury, R., Thiery, J.-P., Rutishauser, U. and Edelman, G (1977). Adhesion among neural cells of the chick embryo. II. Purification and characterization of a cell adhesion molecule from neural retina. J. Biol. Chem 252, 6835-6840.[Abstract/Free Full Text]

Church, G. M. and Gilbert, W (1984). Genomic sequencing. Proc. Nat. Acad Sci USA 81, 1991-1995.[Abstract/Free Full Text]

Cowin, P., Kapprell, H. P., Franke, W. W., Tamkun, J. and Hynes, R. O (1986). Plakoglobin: A protein common to different kinds of intercellular adhering junctions. Cell 46, 1063-1073.[Medline]

Fagotto, F., Funayama, N., Gluck, U. and Gumbiner, B. M (1996). Binding to cadherins antagonizes the signaling activity of-catenin during axis formation in Xenopus. J. Cell Biol 132, 1105-1114.[Abstract/Free Full Text]

Gallin, W. J., Edelman, G. M. and Cunningham, B. A (1983). Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cells. Proc. Nat. Acad Sci USA 80, 1038-1042.[Abstract/Free Full Text]

Gallin, W. J., Sorkin, B. C., Edelman, G. M. and Cunningham, B. A (1987). Sequence analysis of a cDNA clone encoding the liver cell adhesion molecule, L-CAM. Proc. Nat. Acad Sci USA 84, 2808-2812.[Abstract/Free Full Text]

Grunwald, G. B (1993). The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules. Curr. Opin. Cell Biol 5, 797-805.[Medline]

Gumbiner, B (1995). Signal transduction by-catenin. Curr. Opin. Cell Biol 7, 634-640.[Medline]

Gumbiner, B (1996). Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84, 345-357.[Medline]

Hayashi, S., Rubinfeld, B., Souza, B., Polakis, P., Wieschaus, E. and Levine, A. J (1997). A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates-catenin but its zygotic expression is not essential for the regulation of Armadillo. Proc. Nat. Acad Sci USA 94, 242-247.[Abstract/Free Full Text]

Hinck, L., Nathke, I. S., Papkoff, J. and Nelson, W. J (1994). Dynamics of cadherin/catenin complex formation: Novel protein interactions and pathways of complex assembly. J. Cell Biol 125, 1327-1340.[Abstract/Free Full Text]

Hirano, S., Nose, A., Hatta, K., Kawakami, A. and Takeichi, M (1987). Calcium-dependent cell-cell adhesion molecules (cadherins): subclass specificities and possible involvement of actin bundles. J. Cell Biol 105, 2501-2510.[Abstract/Free Full Text]

Islam, S., Carey, T., Wolf, G. T., Wheelock, M. J. and Johnson, K. R (1996). Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion. J. Cell Biol 135, 1643-1654.[Abstract/Free Full Text]

Johnson, K. R., Lewis, J. E., Li, D., Wahl, J., Soler, A. P., Knudsen, K. A. and Wheelock, M. J (1993). P-and E-cadherin are in separate complexes in cell expressing both cadherins. Exp. Cell Res 207, 252-260.[Medline]

Kanani, Y., Ochiai, A., Shibata, T., Oyama, T., Ushijima, S., Akimoto, S. and Hirohashi, S (1995). c- erb B-2 gene product directly associates with-catenin and plakoglobin. Biochem. Biophys. Res. Comm 298, 1067-1072.

Kintner, C (1992). Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell 69, 225-236.[Medline]

Knudsen, K. A. and Wheelock, M. J (1992). Plakoglobin, or an 83-kD homologue distinct from-catenin, interacts with E-cadherin and N-cadherin. J. Cell Biol 118, 671-679.[Abstract/Free Full Text]

Korinek, V., Barker, N., Morin, P. J., van Wichen, D., de Weger, R., Kinzler, K. W., Vogelstein, B. and Clevers, H (1997). Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC/ colon carcinoma. Science 275, 1784-7.[Abstract/Free Full Text]

Kowalczyk, A. P., Palka, H. L., Luu, H. H., Nilles, L. A., Anderson, J. E., Wheelock, M. J. and Green, K. J (1994). Posttranslational regulation of plakoglobin expression. J. Biol. Chem 269, 31214-31223.[Abstract/Free Full Text]

MacCalman, C. D., Furth, E. E., Omigbodun, A. Bronner, Courtifaris, M. C. and Strauss III, J. F (1996). Regulated expression of cadherin-11 in human epithelial cells: a role for cadherin-11 in trophoblast-endometrium interactions?. Dev. Dynam 206, 201-211.[Medline]

Mareel, M., Bracke, M. and Van Roy, F (1995). Cancer metastasis: negative regulation by an invasion-suppressor complex. Cancer Detection and Prevention 19, 451-464.[Medline]

Marrs, J. A. and Nelson, W. J (1996). Cadherin cell adhesion molecules in differentiation and embryogenesis. Int. Rev. Cytol 165, 159-205.[Medline]

Mege, R.-M., Matsuzaki, F., Gallin, W. J., Goldberg, J. I., Cunningham, B. A. and Edelman, G. M (1988). Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules. Proc. Nat. Acad Sci USA 85, 7274-7278.[Abstract/Free Full Text]

Miller, J. R. and Moon, R. T (1996). Signal transduction through-catenin and specification of cell fate during embryogenesis. Genes Dev 10, 2527-2539.[Free Full Text]

Miller, J. R. and Moon, R. T (1997). Analysis of the signaling activities of localization mutants of-catenin during axis specification in Xenopus. J. Cell Biol 139, 229-243.[Abstract/Free Full Text]

Moolenaar, M., van de Wetering, M., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destree, O. and Clevers, H (1996). Xtcf-3 transcription factor mediates-catenin-induced axis formation in Xenopus embryos. Cell 86, 391-399.[Medline]

Munemitsu, S., Albert, I., Souza, B., Rubinfeld, B. and Polakis, P (1995). Regulation of intracellular-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc. Nat. Acad. Sci. USA 92, 3046-3050.[Abstract/Free Full Text]

Nagafuchi, A. and Takeichi, M (1988). Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J 7, 3679-3684.[Medline]

Nagafuchi, A., Ishihara, S. and Tsukita, S (1994). The roles of catenins in cadherin-mediated cell adhesion: functional analysis of E-cadherin--catenin fusion molecules. J. Cell Biol 127, 235-245.[Abstract/Free Full Text]

Nathke, I. S., Hinck, L., Swedlow, J. R., Papkoff, J. and Nelson, W. J (1994). Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells. J. Cell Biol 125, 1341-1352.[Abstract/Free Full Text]

Nicholson, L. J., Pei, X. F. and Watt, F. M (1991). Expression of E-cadherin, P-cadherin and involucrin by normal and neoplastic keratinocytes in culture. Carcinogenesis 12, 1345-1349.[Abstract/Free Full Text]

Nose, A. and Takeichi, M (1986). A novel cadherin in cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryos. J. Cell Biol 103, 2649-2658.[Abstract/Free Full Text]

Nose, A., Nagafuchi, A. and Takeichi, M (1988). Expressed recombinant cadherins mediate cell sorting in model systems. Cell 54, 993-1001.[Medline]

Nose, A., Tsugi, K. and Takeichi, M (1990). Localization of specificity determining sites in cadherin cell adhesion molecules. Cell 61, 147-155.[Medline]

Ozawa, M. and Kemler, R (1992). Molecular organization of the uvomorulin-catenin complex. J. Cell Biol 116, 989-996.[Abstract/Free Full Text]

Ozawa, M., Engel, J. and Kemler, R (1990). Single amino acid substitutions in one Ca2+binding site of uvomorulin abolishes the adhesive function. Cell 63, 1033-1038.[Medline]

Papkoff, J (1997). Regulation of complexed and free catenin pools by distinct mechanisms: differential effects of Wnt-1 and v-Src. J. Biol. Chem 272, 4536-4543.[Abstract/Free Full Text]

Papkoff, J., Rubinfeld, B., Schryver, B. and Polakis, P (1996). Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes. Mol. Cell. Biol 16, 2128-2134.[Abstract]

Pasdar, M., Li, Z. and Chan, H (1995). Desmosome assembly and disassembly are regulated by reversible protein phosphorylation in cultured epithelial cells. Cell Motil. Cytoskel 30, 108-122.[Medline]

Peifer, M (1996). Regulating cell proliferation: as easy as APC. Science 272, 974-975.[Medline]

Peifer, M., McCrea, P. D., Green, K. J., Wieschaus, E. and Gumbiner, B. M (1992). The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties. J. Cell Biol 118, 681-691.[Abstract/Free Full Text]

Piepenhagen, P. A. and Nelson, W. J (1993). Defining E-cadherin associated protein complexes in epithelial cells: plakoglobin,-catenin and g-catenin are distinct components. J. Cell Sci 104, 751-762.[Abstract]

Reid, R. A. and Hemperly, J (1990). Human N-cadherin: nucleotide and deduced amino acid sequence. Nucleic Acids Res 18, 5896-.[Free Full Text]

Rimm, D. L., Koslov, E. R., Kebriaei, P., Cianci, C. D. and Morrow, J. S (1995). 1-(E) catenin is an actin-binding and-bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc. Nat. Acad Sci USA 92, 8813-8817.[Abstract/Free Full Text]

Sacco, P. A., McGranahan, T. M., Wheelock, M. J. and Johnson, K. R (1995). Identification of plakoglobin domains required for association with N-cadherin and-catenin. J. Biol. Chem 270, 20201-20205.[Abstract/Free Full Text]

Shimoyama, Y., Hirohashi, S., Hirano, S., Noguchi, M., Shimosato, Y., Takeichi, M. and Abe, O (1991). Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. Cancer Res 49, 2128-2133.[Abstract/Free Full Text]

Shimoyama, Y., Nagafuchi, A., Fujita, S., Gotoh, M., Takeichi, M., Tsukita, S. and Hirohashi, S (1992). Cadherin dysfunction in a human cancer line: possible involvement of loss of-catenin expression in reduced cell-cell adhesiveness. Cancer Res 52, 5770-5774.[Abstract/Free Full Text]

Sorkin, B. C., Jones, F. S., Cunningham, B. A. and Edelman, G. M (1993). Identification of the promoter and a transcriptional enhancer of the gene encoding L-CAM, a calcium-dependent cell adhesion molecule. Proc. Nat. Acad Sci USA 90, 11356-113560.[Abstract/Free Full Text]

Takeichi, M (1987). Cadherins: a molecular family essential for selective cell-cell adhesion and animal morphogenesis. Trends Genet 3, 213-217.

Takeichi, M (1991). Cadherin cell adhesion receptors as morphogenetic regulator. Science 251, 1451-1455.[Abstract/Free Full Text]

Takeichi, M (1993). Cadherins in cancer: implications for invasion and metastasis. Curr. Opin. Cell Biol 5, 806-811.[Medline]

Takeichi, M (1995). Morphogenetic roles of classic cadherins. Curr. Opin. Cell Biol 7, 619-627.[Medline]

Towbin, H., Staehlin, T. and Gordon, G (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedures and some applications. Proc. Nat. Acad Sci USA 76, 4350-4354.[Abstract/Free Full Text]

Vestweber, D. and Kemler, R (1985). Identification of a putative cell adhesion domain of uvomorulin. EMBO J 4, 3393-3398.[Medline]

Watt, F. M (1989). Terminal differentiation of epidermal keratinocytes. Curr. Opin. Cell Biol 1, 1107-1115.[Medline]

Wheelock, M. J. and Jensen, P. J (1992). Regulation of keratinocyte intercellular junction organization and epidermal morphogenesis by E-cadherin. J. Cell Biol 117, 415-425.[Abstract/Free Full Text]

This article has been cited by other articles:

M. Mareel and A. Leroy
Clinical, Cellular, and Molecular Aspects of Cancer Invasion
Physiol Rev, April 1, 2003; 83(2): 337 - 376.
[Abstract] [Full Text] [PDF]

M. Jones, P. J.B. Sabatini, F. S.H. Lee, M. P. Bendeck, and B. L. Langille
N-Cadherin Upregulation and Function in Response of Smooth Muscle Cells to Arterial Injury
Arterioscler. Thromb. Vasc. Biol., December 1, 2002; 22(12): 1972 - 1977.
[Abstract] [Full Text] [PDF]

M. L. Taddei, P. Chiarugi, P. Cirri, F. Buricchi, T. Fiaschi, E. Giannoni, D. Talini, G. Cozzi, L. Formigli, G. Raugei, et al.
{beta}-Catenin Interacts with Low-Molecular-Weight Protein Tyrosine Phosphatase Leading to Cadherin-mediated Cell-Cell Adhesion Increase
Cancer Res., November 15, 2002; 62(22): 6489 - 6499.
[Abstract] [Full Text] [PDF]

M. Renaud-Young and W. J. Gallin
In the First Extracellular Domain of E-cadherin, Heterophilic Interactions, but Not the Conserved His-Ala-Val Motif, Are Required for Adhesion
J. Biol. Chem., October 11, 2002; 277(42): 39609 - 39616.
[Abstract] [Full Text] [PDF]

J.-B. Kim, S. Islam, Y. J. Kim, R. S. Prudoff, K. M. Sass, M. J. Wheelock, and K. R. Johnson
N-Cadherin Extracellular Repeat 4 Mediates Epithelial to Mesenchymal Transition and Increased Motility
J. Cell Biol., December 11, 2000; 151(6): 1193 - 1206.
[Abstract] [Full Text] [PDF]

S. Hakimelahi, H. R. Parker, A. J. Gilchrist, M. Barry, Z. Li, R. C. Bleackley, and M. Pasdar
Plakoglobin Regulates the Expression of the Anti-apoptotic Protein BCL-2
J. Biol. Chem., April 6, 2000; 275(15): 10905 - 10911.
[Abstract] [Full Text] [PDF]

M Hsu, T Andl, G Li, J. Meinkoth, and M Herlyn
Cadherin repertoire determines partner-specific gap junctional communication during melanoma progression
J. Cell Sci., January 5, 2000; 113(9): 1535 - 1542.
[Abstract] [PDF]

E. S. Wittchen, J. Haskins, and B. R. Stevenson
Protein Interactions at the Tight Junction. ACTIN HAS MULTIPLE BINDING PARTNERS, AND ZO-1 FORMS INDEPENDENT COMPLEXES WITH ZO-2 AND ZO-3
J. Biol. Chem., December 3, 1999; 274(49): 35179 - 35185.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Li, Z.

Articles by Pasdar, M.

Search for Related Content

PubMed

PubMed Citation

Articles by Li, Z.

Articles by Pasdar, M.

				M. Jones, P. J.B. Sabatini, F. S.H. Lee, M. P. Bendeck, and B. L. Langille N-Cadherin Upregulation and Function in Response of Smooth Muscle Cells to Arterial Injury Arterioscler. Thromb. Vasc. Biol., December 1, 2002; 22(12): 1972 - 1977. [Abstract] [Full Text] [PDF]

				M. L. Taddei, P. Chiarugi, P. Cirri, F. Buricchi, T. Fiaschi, E. Giannoni, D. Talini, G. Cozzi, L. Formigli, G. Raugei, et al. {beta}-Catenin Interacts with Low-Molecular-Weight Protein Tyrosine Phosphatase Leading to Cadherin-mediated Cell-Cell Adhesion Increase Cancer Res., November 15, 2002; 62(22): 6489 - 6499. [Abstract] [Full Text] [PDF]

				M. Renaud-Young and W. J. Gallin In the First Extracellular Domain of E-cadherin, Heterophilic Interactions, but Not the Conserved His-Ala-Val Motif, Are Required for Adhesion J. Biol. Chem., October 11, 2002; 277(42): 39609 - 39616. [Abstract] [Full Text] [PDF]

				J.-B. Kim, S. Islam, Y. J. Kim, R. S. Prudoff, K. M. Sass, M. J. Wheelock, and K. R. Johnson N-Cadherin Extracellular Repeat 4 Mediates Epithelial to Mesenchymal Transition and Increased Motility J. Cell Biol., December 11, 2000; 151(6): 1193 - 1206. [Abstract] [Full Text] [PDF]

				S. Hakimelahi, H. R. Parker, A. J. Gilchrist, M. Barry, Z. Li, R. C. Bleackley, and M. Pasdar Plakoglobin Regulates the Expression of the Anti-apoptotic Protein BCL-2 J. Biol. Chem., April 6, 2000; 275(15): 10905 - 10911. [Abstract] [Full Text] [PDF]

				M Hsu, T Andl, G Li, J. Meinkoth, and M Herlyn Cadherin repertoire determines partner-specific gap junctional communication during melanoma progression J. Cell Sci., January 5, 2000; 113(9): 1535 - 1542. [Abstract] [PDF]

				E. S. Wittchen, J. Haskins, and B. R. Stevenson Protein Interactions at the Tight Junction. ACTIN HAS MULTIPLE BINDING PARTNERS, AND ZO-1 FORMS INDEPENDENT COMPLEXES WITH ZO-2 AND ZO-3 J. Biol. Chem., December 3, 1999; 274(49): 35179 - 35185. [Abstract] [Full Text] [PDF]