Differential regulation of hepatocyte growth factor/scatter factor by cell surface proteoglycans and free glycosaminoglycan chains

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Deakin, J. A.
	Articles by Lyon, M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Deakin, J. A.
	Articles by Lyon, M.

Ashikari, S., Habuchi, H. and Kimata, K (1995). Characterisation of heparan sulphate oligosaccharides that bind to hepatocyte growth factor. J. Biol. Chem 49, 29586-29593.

Bardelli, A., Maina, F., Gout, I., Fry, M. J., Waterfield, M. D., Comoglio, P. M. and Ponzetto, C (1992). Autophosphorylation promotes complex formation of recombinant hepatocyte growth factor receptor with cytoplasmic effectors containing SH2 domains. Oncogene 7, 1973-1978.[Medline]

Baeuerle, P. A. and Huttner, W. B (1986). Chlorate- a potent inhibitor of protein sulphation in intact cells. Biochem. Biophys. Res. Commun 141, 870-877.[Medline]

Chirgadze, D. Y., Hepple, J., Byrd, R. A., Sowdhamini, R., Blundell, T. L. and Gherardi, E (1998). Insights into the structure of hepatocyte growth factor/scatter factor (HGF/SF) and implications for receptor activation. FEBS Lett 430, 126-129.[Medline]

Davies, J., Lyon, M., Gallagher, J. T. and Garrod, D (1995). Sulphated proteoglycan is required for collecting duct growth and branching but not nephron formation during kidney development. Development 121, 1507-1517.[Abstract]

Farley, J. R., Nakayama, G., Cryns, D. and Sagel, I. H (1978). Adenosine triphosphate sulphurylase from Penicillium chrysogencium : equilibrium binding, substrate hydrolysis and isotope exchange studies. Arch. Biochem. Biophys 185, 376-390.[Medline]

Fournier, T. M., Kamikura, D., Teng, K. and Park, M (1996). Branching tubulogenesis but not scatter of Madin-Darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase. J. Biol. Chem 271, 22211-22217.[Abstract/Free Full Text]

Gallagher, J. T (1998). The interaction and regulation of basic and acidic fibroblast growth factors by heparan sulphate. Trends Genet 10, 137-144.

Hardingham, T. E (1979). The role of link protein in the structure of cartilage proteoglycan aggregates. Biochem. J 177, 237-247.[Medline]

Hartmann, G., Naldini, L., Weidner, K. M., Sachs, M., Vigna, E., Comoglio, P. M. and Birchmeier, W (1992). A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. Proc. Natl. Acad. Sci. USA 89, 11574-11578.[Abstract/Free Full Text]

Jeffers, M., Rong, S. and Vande Woude, G. F (1996). Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis. J. Mol. Med 74, 505-513.[Medline]

Khwaja, A., Lehmann, K., Marte, B. M. and Downward, J (1998). Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway. J. Biol. Chem 30, 18793-18801.

Kinosaki, M., Yamaguchi, K., Murakami, A., Ueda, M., Morinaga, T. and Higashio, K (1998). Identification of heparin-binding stretches of a naturally occurring deleted variant of hepatocyte growth factor (dHGF). Biochim. Biophys. Acta 1384, 93-102.[Medline]

Lokker, N. A., Mark, M. R., Luis, E. A., Bennett, G. L., Robbins, K. A., Baker, J. B. and Godowski, P. J. ( (1992). Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding. EMBO J 11, 2503-2510.[Medline]

Lokker, N. A., Presta, L. G. and Godowski, P. J (1994). Mutational analysis and molecular modeling of the N-terminal kringle-containing domain of hepatocyte growth factor identifies amino acid side chains important for interaction with the c-Met receptor. Protein Engineering 7, 895-903.[Abstract/Free Full Text]

Lyon, M. and Gallagher, J. T (1991). Purification and partial characterization of the major cell-associated heparan sulphate proteoglycan of rat liver. Biochem. J 273, 415-422.

Lyon, M., Deakin, J. A., Mizuno, K., Nakamura, T. and Gallagher, J. T (1994). Interaction of hepatocyte growth factor with heparan sulphate. J. Biol. Chem 269, 11216-11223.[Abstract/Free Full Text]

Lyon, M., Deakin, J. A. and Gallagher, J. T (1994). Liver heparan sulphate structure: a novel molecular design. J. Biol. Chem 269, 11208-11215.[Abstract/Free Full Text]

Lyon, M., Deakin, J. A., Rahmoune, H., Fernig, D. G. and Gallagher, J. T.( (1998). Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulphate. J. Biol. Chem 273, 271-278.[Abstract/Free Full Text]

Mark, M. R., Lokker, N. A., Zioncheck, T. F., Luis, E. A. and Godowski, P. J (1992). Expression and characterisation of hepatocyte growth factor receptor-IgG Fusion Proteins: effects of mutations in the potential proteolytic cleavage site on processing and ligand binding. J. Biol. Chem 267, 26166-26171.[Abstract/Free Full Text]

Matsumoto, K. and Nakamura, T (1996). Emerging multipotent aspects of hepatocyte growth factor. J. Biochem 119, 591-600.

Matsumoto, K., Kataoka, H., Date, K. and Nakamura, T (1998). Cooperative interaction between-and -chains of hepatocyte growth factor on c-Met receptor confers ligand-induced receptor tyrosine phosphorylation and multiple biological responses. J. Biol. Chem 273, 22913-22920.[Abstract/Free Full Text]

Miller, M. and Leonard, E. J (1998). Mode of receptor binding and activation by plasminogen-related growth factors. FEBS Lett 429, 1-3.[Medline]

Mizuno, K., Inoue, H., Hagiya, M., Shimizu, S., Nose, T., Shimohigashi, Y. and Nakamura, T (1994). Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor. J. Biol. Chem 269, 1131-1136.[Abstract/Free Full Text]

Naka, D., Ishii, T., Shimomura, T., Hishida, T. and Hara, H (1993). Heparin modulates the receptor-binding and mitogenic activity of hepatocyte growth factor on hepatocytes. Exp. Cell. Res 209, 317-324.[Medline]

Naldini, L., Weidner, K. M., Vigna, E., Gaudino, G., Bardelli, A., Ponzetto, C., Narsimhan, R. P., Hartmann, G., Zarnegar, R., Michalopoulos, G. K., Birchmeier, W. and Comoglio, P. M (1991). Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO. J 10, 2867-2878.[Medline]

Okigaki, M., Komada, M., Uehara, Y., Miyazawa, K. and Kitamura, N (1992). Functional characterization of human hepatocyte growth factor mutants obtained by deletion of structural domains. Biochemistry 31, 9555-9561.[Medline]

Pearson, C. H., Winterbottom, N., Fackre, D. S., Scott, P. G. and Carpenter, M. R (1983). The NH2-terminal amino acid sequence of bovine skin proteodermatan sulphate. J. Biol. Chem 258, 15101-15104.[Abstract/Free Full Text]

Pierce, A., Lyon, M., Hampson, I., Cowling, G. J. and Gallagher, J. T (1992). Molecular cloning of the major cell surface heparan sulphate proteoglycan from rat liver. J. Biol. Chem 267, 3894-3900.[Abstract/Free Full Text]

Ponzetto, C., Bardelli, A., Zhen, Z., Maina, F., dalla Zonca, P., Giordano, S., Graziani, A., Panayotou, G. and Comoglio, P. M (1994). A multifunctional docking site mediates signalling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 77, 261-271.[Medline]

Ponzetto, C., Zhen, Z., Audero, E., Maina, F., Bardelli, A., Basile, M. L., Giordano, S., Narsinham, R. and Comoglio, P (1996). Specific uncoupling of Grb2 from the Met receptor: differential effects on transformation and motility. J. Biol. Chem 271, 14119-14123.[Abstract/Free Full Text]

Prat, M., Crepaldi, T., Pennacchietti, S., Bussolino, F. and Comoglio, P. M (1998). Agonistic monoclonal antibodies against the Met receptor dissect the biological responses to HGF. J. Cell. Sci 111, 237-247.[Abstract]

Rahmoune, H., Chen, H.-L., Gallagher, J. T., Rudland, P. S. and Fernig, D. G (1998). Interaction of heparan sulfate from mammary cells with aFGF and bFGF: regulation of the activity of bFGF by high and low affinity binding sites in heparan sulphate. J. Biol. Chem 273, 7303-7310.[Abstract/Free Full Text]

Rahmoune, H., Rudland, P. S., Gallagher, J. T. and Fernig, D. G (1998). Hepatocyte growth factor/scatter factor has three classes of binding site in heparan sulphate from mammary cells. Biochemistry 37, 6003-6008.[Medline]

Rapraeger, A. C., Krufka, A. and Olwin, B. B (1991). Requirement of heparan sulphate for bFGF-mediated fibroblast growth and myoblast differentiation. Science 252, 1705-1708.[Abstract/Free Full Text]

Rosen, E. M., Goldberg, I. D., Kacinski, B. M., Buckholz, T. and Vinter, D. W (1989). Smooth muscle releases an epithelial cell scatter factor which binds to heparin. In Vitro 25, 163-173.

Rosen, E. M., Meromsky, L., Goldberg, I., Bhargava, M. and Setter, E (1990). Studies on the mechanism of scatter factor: effects of agents that modulate intracellular signal transduction, macromolecule synthesis and cytoskeleton assembly. J. Cell. Sci 96, 639-649.[Abstract/Free Full Text]

Rubin, J. S., Chan, A. M.-L., Bottaro, D. P., Burgess, W. H., Taylor, W. G., Cech, A. C., Hirschfield, D. W., Wong, J., Miki, T., Finch, P. W. and Aaronson, S. A (1991). A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. Proc. Natl. Acad. Sci. USA 88, 415-419.[Abstract/Free Full Text]

Sakata, H., Stahl, S. J., Taylor, W. G., Rosenberg, J. M., Sakaguchi, K., Wingfield, P. T. and Rubin, J. S (1997). Heparin binding and oligomerization of hepatocyte growth factor/scatter factor isoforms: heparan sulphate glycosaminoglycan requirement for Met binding and signaling. J. Biol. Chem 272, 9457-9463.[Abstract/Free Full Text]

Schwall, R. H., Chang, L. Y., Godowski, P. J., Kahn, D. W., Hillan, K. J., Bauer, K. D. and Zioncheck, T. F (1996). Heparin induces dimerisation and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2. J. Cell. Biol 133, 709-718.[Abstract/Free Full Text]

Stoker, M., Gherardi, E., Perryman, M. and Gray, J (1987). Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 327, 239-242.[Medline]

Stoker, M (1989). Effect of scatter factor on motility of epithelial cells and fibroblasts. J. Cell. Physiol 139, 565-569.[Medline]

Svennevig, K., Prydz, K. and Kolset, S. O (1995). Proteoglycans in polarized epithelial Madin-Darby canine kidney cells. Biochem. J 311, 881-888.

Tajima, H., Matsumoto, K. and Nakamura, T (1992). Regulation of cell growth and motility by hepatocyte growth factor and receptor expression in various cell species. Exp. Cell. Res 202, 423-431.[Medline]

Tamagnone, L. and Comoglio, P. M (1997). Control of invasive growth by hepatocyte growth factor (HGF) and related scatter factors. Cytokine & Growth Factor Reviews 8, 129-142.[Medline]

Tanimura, S., Chatani, Y., Hoshino, R., Sato, M., Watanabe, S.-I., Kataoka, T., Nakamura, T. and Kohno, M (1998). Activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway is required for hepatocyte growth factor-induced cell scattering. Oncogene 17, 57-65.[Medline]

Trusolino, L., Pugliese, L. and Comoglio, P. M (1998). Interactions between scatter factors and their receptors: hints for therapeutic applications. FASEB J 12, 1267-1280.[Abstract/Free Full Text]

Weidner, K. M., Sachs, M. and Birchmeier, W (1993). The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells. J. Cell. Biol 121, 145-154.[Abstract/Free Full Text]

Zarnegar, R. and Michalopoulos, G (1989). Purification and biological characterisation of human hepatopoietin A, a polypeptide growth factor for hepatocytes. Cancer Res 49, 3314-3320.[Abstract/Free Full Text]

Zarnegar, R., DeFrances, M. C., Oliver, L. and Michalopoulos, G (1990). Identification and partial characterization of receptor binding sites for HGF on rat hepatocytes. Biochem. Biophys Res. Comm 173, 1179-1185.[Medline]

Zioncheck, T. F., Richardson, L., Liu, J., Chang, L., King, K. L., Bennett, G. L., Fugedi, P., Chamow, S. M., Schwall, R. H. and Stack, R. J (1995). Sulphated oligosaccharides promote hepatocyte growth factor association and govern its mitogenic activity. J. Biol. Chem 270, 16871-16878.[Abstract/Free Full Text]

This article has been cited by other articles:

S. A. Osborne, R. A. Daniel, K. Desilva, and R. B. Seymour
Antithrombin activity and disaccharide composition of dermatan sulfate from different bovine tissues
Glycobiology, March 1, 2008; 18(3): 225 - 234.
[Abstract] [Full Text] [PDF]

K. R. Catlow, J. A. Deakin, Z. Wei, M. Delehedde, D. G. Fernig, E. Gherardi, J. T. Gallagher, M. S. G. Pavao, and M. Lyon
Interactions of Hepatocyte Growth Factor/Scatter Factor with Various Glycosaminoglycans Reveal an Important Interplay between the Presence of Iduronate and Sulfate Density
J. Biol. Chem., February 29, 2008; 283(9): 5235 - 5248.
[Abstract] [Full Text] [PDF]

S. Sirko, A. von Holst, A. Wizenmann, M. Gotz, and A. Faissner
Chondroitin sulfate glycosaminoglycans control proliferation, radial glia cell differentiation and neurogenesis in neural stem/progenitor cells
Development, August 1, 2007; 134(15): 2727 - 2738.
[Abstract] [Full Text] [PDF]

F. Li, A. K. Shetty, and K. Sugahara
Neuritogenic Activity of Chondroitin/Dermatan Sulfate Hybrid Chains of Embryonic Pig Brain and Their Mimicry from Shark Liver: INVOLVEMENT OF THE PLEIOTROPHIN AND HEPATOCYTE GROWTH FACTOR SIGNALING PATHWAYS
J. Biol. Chem., February 2, 2007; 282(5): 2956 - 2966.
[Abstract] [Full Text] [PDF]

M. Lyon, J. A. Deakin, D. Lietha, E. Gherardi, and J. T. Gallagher
The Interactions of Hepatocyte Growth Factor/Scatter Factor and Its NK1 and NK2 Variants with Glycosaminoglycans Using a Modified Gel Mobility Shift Assay: ELUCIDATION OF THE MINIMAL SIZE OF BINDING AND ACTIVATORY OLIGOSACCHARIDES
J. Biol. Chem., October 15, 2004; 279(42): 43560 - 43567.
[Abstract] [Full Text] [PDF]

A. Karihaloo, S. Kale, N. D. Rosenblum, and L. G. Cantley
Hepatocyte Growth Factor-Mediated Renal Epithelial Branching Morphogenesis Is Regulated by Glypican-4 Expression
Mol. Cell. Biol., October 1, 2004; 24(19): 8745 - 8752.
[Abstract] [Full Text] [PDF]

S. Ashikari-Hada, H. Habuchi, Y. Kariya, N. Itoh, A. H. Reddi, and K. Kimata
Characterization of Growth Factor-binding Structures in Heparin/Heparan Sulfate Using an Octasaccharide Library
J. Biol. Chem., March 26, 2004; 279(13): 12346 - 12354.
[Abstract] [Full Text] [PDF]

P. Devarajan
Has HGF met other partners? Met-independent epithelial morphogenesis induced by HGF. Focus on "Hepatocyte growth factor induces MDCK cell morphogenesis without causing loss of tight junction functional integrity"
Am J Physiol Cell Physiol, March 1, 2004; 286(3): C475 - C477.
[Full Text] [PDF]

A. L. Pollack, G. Apodaca, and K. E. Mostov
Hepatocyte growth factor induces MDCK cell morphogenesis without causing loss of tight junction functional integrity
Am J Physiol Cell Physiol, March 1, 2004; 286(3): C482 - C494.
[Abstract] [Full Text]

M. Delehedde, M. Lyon, R. Vidyasagar, T. J. McDonnell, and D. G. Fernig
Hepatocyte Growth Factor/Scatter Factor Binds to Small Heparin-derived Oligosaccharides and Stimulates the Proliferation of Human HaCaT Keratinocytes
J. Biol. Chem., March 29, 2002; 277(14): 12456 - 12462.
[Abstract] [Full Text] [PDF]

D. Bechard, T. Gentina, M. Delehedde, A. Scherpereel, M. Lyon, M. Aumercier, R. Vazeux, C. Richet, P. Degand, B. Jude, et al.
Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate Proteoglycan That Promotes Hepatocyte Growth Factor/Scatter Factor Mitogenic Activity
J. Biol. Chem., December 14, 2001; 276(51): 48341 - 48349.
[Abstract] [Full Text] [PDF]

A. Karihaloo, S. A. Karumanchi, J. Barasch, V. Jha, C. H. Nickel, J. Yang, S. Grisaru, K. T. Bush, S. Nigam, N. D. Rosenblum, et al.
Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud
PNAS, October 12, 2001; (2001) 221205198.
[Abstract] [Full Text] [PDF]

C. Seidel, M. Borset, O. Hjertner, D. Cao, N. Abildgaard, H. Hjorth-Hansen, R. D. Sanderson, A. Waage, and A. Sundan
High levels of soluble syndecan-1 in myeloma-derived bone marrow: modulation of hepatocyte growth factor activity
Blood, November 1, 2000; 96(9): 3139 - 3146.
[Abstract] [Full Text] [PDF]

S. Salek-Ardakani, J. R. Arrand, D. Shaw, and M. Mackett
Heparin and heparan sulfate bind interleukin-10 and modulate its activity
Blood, September 1, 2000; 96(5): 1879 - 1888.
[Abstract] [Full Text] [PDF]

N. Sergeant, M. Lyon, P. S. Rudland, D. G. Fernig, and M. Delehedde
Stimulation of DNA Synthesis and Cell Proliferation of Human Mammary Myoepithelial-like Cells by Hepatocyte Growth Factor/Scatter Factor Depends on Heparan Sulfate Proteoglycans and Sustained Phosphorylation of Mitogen-activated Protein Kinases p42/44
J. Biol. Chem., May 26, 2000; 275(22): 17094 - 17099.
[Abstract] [Full Text] [PDF]

C. Riquelme, J. Larrain, E. Schonherr, J. P. Henriquez, H. Kresse, and E. Brandan
Antisense Inhibition of Decorin Expression in Myoblasts Decreases Cell Responsiveness to Transforming Growth Factor beta and Accelerates Skeletal Muscle Differentiation
J. Biol. Chem., January 26, 2001; 276(5): 3589 - 3596.
[Abstract] [Full Text] [PDF]

M. Delehedde, M. Seve, N. Sergeant, I. Wartelle, M. Lyon, P. S. Rudland, and D. G. Fernig
Fibroblast Growth Factor-2 Stimulation of p42/44MAPK Phosphorylation and Ikappa B Degradation Is Regulated by Heparan Sulfate/Heparin in Rat Mammary Fibroblasts
J. Biol. Chem., October 20, 2000; 275(43): 33905 - 33910.
[Abstract] [Full Text] [PDF]

M. Lyon, J. A. Deakin, and J. T. Gallagher
The Mode of Action of Heparan and Dermatan Sulfates in the Regulation of Hepatocyte Growth Factor/Scatter Factor
J. Biol. Chem., January 4, 2002; 277(2): 1040 - 1046.
[Abstract] [Full Text] [PDF]

A. Karihaloo, S. A. Karumanchi, J. Barasch, V. Jha, C. H. Nickel, J. Yang, S. Grisaru, K. T. Bush, S. Nigam, N. D. Rosenblum, et al.
Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud
PNAS, October 23, 2001; 98(22): 12509 - 12514.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Deakin, J. A.

Articles by Lyon, M.

Search for Related Content

PubMed

PubMed Citation

Articles by Deakin, J. A.

Articles by Lyon, M.

				K. R. Catlow, J. A. Deakin, Z. Wei, M. Delehedde, D. G. Fernig, E. Gherardi, J. T. Gallagher, M. S. G. Pavao, and M. Lyon Interactions of Hepatocyte Growth Factor/Scatter Factor with Various Glycosaminoglycans Reveal an Important Interplay between the Presence of Iduronate and Sulfate Density J. Biol. Chem., February 29, 2008; 283(9): 5235 - 5248. [Abstract] [Full Text] [PDF]

				S. Sirko, A. von Holst, A. Wizenmann, M. Gotz, and A. Faissner Chondroitin sulfate glycosaminoglycans control proliferation, radial glia cell differentiation and neurogenesis in neural stem/progenitor cells Development, August 1, 2007; 134(15): 2727 - 2738. [Abstract] [Full Text] [PDF]

				F. Li, A. K. Shetty, and K. Sugahara Neuritogenic Activity of Chondroitin/Dermatan Sulfate Hybrid Chains of Embryonic Pig Brain and Their Mimicry from Shark Liver: INVOLVEMENT OF THE PLEIOTROPHIN AND HEPATOCYTE GROWTH FACTOR SIGNALING PATHWAYS J. Biol. Chem., February 2, 2007; 282(5): 2956 - 2966. [Abstract] [Full Text] [PDF]

				M. Lyon, J. A. Deakin, D. Lietha, E. Gherardi, and J. T. Gallagher The Interactions of Hepatocyte Growth Factor/Scatter Factor and Its NK1 and NK2 Variants with Glycosaminoglycans Using a Modified Gel Mobility Shift Assay: ELUCIDATION OF THE MINIMAL SIZE OF BINDING AND ACTIVATORY OLIGOSACCHARIDES J. Biol. Chem., October 15, 2004; 279(42): 43560 - 43567. [Abstract] [Full Text] [PDF]

				A. Karihaloo, S. Kale, N. D. Rosenblum, and L. G. Cantley Hepatocyte Growth Factor-Mediated Renal Epithelial Branching Morphogenesis Is Regulated by Glypican-4 Expression Mol. Cell. Biol., October 1, 2004; 24(19): 8745 - 8752. [Abstract] [Full Text] [PDF]

				S. Ashikari-Hada, H. Habuchi, Y. Kariya, N. Itoh, A. H. Reddi, and K. Kimata Characterization of Growth Factor-binding Structures in Heparin/Heparan Sulfate Using an Octasaccharide Library J. Biol. Chem., March 26, 2004; 279(13): 12346 - 12354. [Abstract] [Full Text] [PDF]

				P. Devarajan Has HGF met other partners? Met-independent epithelial morphogenesis induced by HGF. Focus on "Hepatocyte growth factor induces MDCK cell morphogenesis without causing loss of tight junction functional integrity" Am J Physiol Cell Physiol, March 1, 2004; 286(3): C475 - C477. [Full Text] [PDF]

				A. L. Pollack, G. Apodaca, and K. E. Mostov Hepatocyte growth factor induces MDCK cell morphogenesis without causing loss of tight junction functional integrity Am J Physiol Cell Physiol, March 1, 2004; 286(3): C482 - C494. [Abstract] [Full Text]

				M. Delehedde, M. Lyon, R. Vidyasagar, T. J. McDonnell, and D. G. Fernig Hepatocyte Growth Factor/Scatter Factor Binds to Small Heparin-derived Oligosaccharides and Stimulates the Proliferation of Human HaCaT Keratinocytes J. Biol. Chem., March 29, 2002; 277(14): 12456 - 12462. [Abstract] [Full Text] [PDF]

				D. Bechard, T. Gentina, M. Delehedde, A. Scherpereel, M. Lyon, M. Aumercier, R. Vazeux, C. Richet, P. Degand, B. Jude, et al. Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate Proteoglycan That Promotes Hepatocyte Growth Factor/Scatter Factor Mitogenic Activity J. Biol. Chem., December 14, 2001; 276(51): 48341 - 48349. [Abstract] [Full Text] [PDF]

				A. Karihaloo, S. A. Karumanchi, J. Barasch, V. Jha, C. H. Nickel, J. Yang, S. Grisaru, K. T. Bush, S. Nigam, N. D. Rosenblum, et al. Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud PNAS, October 12, 2001; (2001) 221205198. [Abstract] [Full Text] [PDF]

				C. Seidel, M. Borset, O. Hjertner, D. Cao, N. Abildgaard, H. Hjorth-Hansen, R. D. Sanderson, A. Waage, and A. Sundan High levels of soluble syndecan-1 in myeloma-derived bone marrow: modulation of hepatocyte growth factor activity Blood, November 1, 2000; 96(9): 3139 - 3146. [Abstract] [Full Text] [PDF]

				S. Salek-Ardakani, J. R. Arrand, D. Shaw, and M. Mackett Heparin and heparan sulfate bind interleukin-10 and modulate its activity Blood, September 1, 2000; 96(5): 1879 - 1888. [Abstract] [Full Text] [PDF]

				N. Sergeant, M. Lyon, P. S. Rudland, D. G. Fernig, and M. Delehedde Stimulation of DNA Synthesis and Cell Proliferation of Human Mammary Myoepithelial-like Cells by Hepatocyte Growth Factor/Scatter Factor Depends on Heparan Sulfate Proteoglycans and Sustained Phosphorylation of Mitogen-activated Protein Kinases p42/44 J. Biol. Chem., May 26, 2000; 275(22): 17094 - 17099. [Abstract] [Full Text] [PDF]

				C. Riquelme, J. Larrain, E. Schonherr, J. P. Henriquez, H. Kresse, and E. Brandan Antisense Inhibition of Decorin Expression in Myoblasts Decreases Cell Responsiveness to Transforming Growth Factor beta and Accelerates Skeletal Muscle Differentiation J. Biol. Chem., January 26, 2001; 276(5): 3589 - 3596. [Abstract] [Full Text] [PDF]

				M. Delehedde, M. Seve, N. Sergeant, I. Wartelle, M. Lyon, P. S. Rudland, and D. G. Fernig Fibroblast Growth Factor-2 Stimulation of p42/44MAPK Phosphorylation and Ikappa B Degradation Is Regulated by Heparan Sulfate/Heparin in Rat Mammary Fibroblasts J. Biol. Chem., October 20, 2000; 275(43): 33905 - 33910. [Abstract] [Full Text] [PDF]

				M. Lyon, J. A. Deakin, and J. T. Gallagher The Mode of Action of Heparan and Dermatan Sulfates in the Regulation of Hepatocyte Growth Factor/Scatter Factor J. Biol. Chem., January 4, 2002; 277(2): 1040 - 1046. [Abstract] [Full Text] [PDF]