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Badman, M. K., Shennan, K. I. J., Jermany, J. L., Docherty, K. and Clark A (1996). Processing of proislet amyloid polypeptide (ProIAPP) by the prohormone convertase PC2. FEBS Lett 378, 227-231.[Medline]

Clark, A (1992). Islet amyloid: an enigma of Type 2 diabetes. Diabetes Metab. Rev 8, 117-132.[Medline]

Clark, A., de Koning, E. J. P., Baker, C. A., Charge, S. and Morris, J. F (1993). Localisation of N-terminal pro-islet amyloid polypeptide in-cells of man and transgenic mice. Diabetologia 36, 136-.

Clark, A., Wells, C. A., Buley, I. D., Cruickshank, J. K., Vanhegan, R. I., Matthews, D. R., Cooper, G. J., Holman, R. R. and Turner, R. C (1988). . Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes. Diabetes Res 9, 151-159.[Medline]

Cruts, M., Hendriks, L. and van Broeckhoven, C (1996). The presenilin genes: a new gene family involved in Alzheimer disease pathology. Human Mol. Genetics 5, 1449-1455.[Abstract]

Dahl, U., Sjodin, A. and Semb, H (1996). Cadherins regulate aggregation of pancreatic-cells in vivo. Development 122, 2895-2902.[Abstract]

de Fronzo, R. A., Ferrannini, E. and Simmonson, D. C (1989). Fasting hyperglycaemia in non-insulin dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake. Metabolism 39, 387-395.

de Koning, E. J. P., H\232ppener, J. W. M., Oosterwijk, C., Verbeek, J. S., Visser, H. S., Jansz, H. S., Lips, C. J. M., Morris, J. F. and Clark, A (1992). Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans. Diabetes 43, 640-644.[Abstract]

Deng, G., Pike, C. J. and Cotman, C. W (1996). Alzheimer-associated presenilin-2 confers increased sensitvity to apoptosis in PC12 cells. FEBS Lett 397, 50-54.[Medline]

de Strooper, B., Beullens, M., Contreras, B., Levesque, L., Craessaerts, K., Cordell, B., Moechars, D., Bollen, M., Fraser, P. E., St George-Hyslop, P. et al (1997). Phosphorylation, subcellular localisation and membrane orientation of the Alzheimer's disease-associated presenilins. J. Biol. Chem 272, 3590-3598.[Abstract/Free Full Text]

Frayling, T. M., Bulman, M. P., Ellard, S., Appleton, M., Dronsfield, M. J., Mackie, A. D. R., Baird, J. D., Kaisaki, P. J., Yamagata, K., Bell, G. I. et al (1997). Mutations in hepatocyte nuclear factor alpha are a common cause of maturity onset diabetes of the young in the UK. Diabetes 46, 720-725.[Abstract]

Gavin III, J. R., Alberti, K. G. M. M., Davidson, M. B., DeFronz, R. A., Drash, A., Gabbe, S. G., Genuth, S., Harris, M. I., Kahn, R., Keen, H. et al (1997). Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 20, 1183-1197.[Medline]

Guo, Q., Sopher, B. L., Furukawa, K., Pham, D. G., Robinson, N., Martin, G. M. and Mattson, M. P (1997). Alzheimer's presenilin mutation sensitises neural cells to apoptosis induced by trophic factor withdrawal and amyloid-peptide: involvement of calcium and oxyradicals. J. Neurosci 17, 4212-4222.[Abstract/Free Full Text]

Hutton, J. C (1994). Insulin secretory granule biogenesis and the proinsulin-processing endopeptidases. Diabetologia 37, 2-.

Kaprio, J., Tuomilehto, J., Koshenvuo, M., Romanov, K., Reunanen, A., Eriksson, J., Steng\214rd, J. and Kes\212niemi, Y. A (1992). Concordance for Type 1 (insulin dependent) and Type 2 (non-insulin-dependent) diabetes mellitus in a population based cohort of twins in Finland. Diabetologia 35, 1060-1067.[Medline]

Kim, T. W., Pettingel, W. H., Hallmark, O. G., Moir, R. D., Wasco, W. and Tanzi, R. E (1997). Endoproteolytic cleavage and proteosomal degradation of presenilin 2 in transfected cells. J. Biol. Chem 272, 11006-11010.[Abstract/Free Full Text]

Levitan, D. and Greenwald, I (1995). Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377, 351-354.[Medline]

Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D. M., Oshima, J., Pettingell, W. H., Yu, C., Jondro, P. D., Schmidt, S. D., Wang, K., et al (1995). Candidate gene for the chromosome 1 familial Alzheimer's Disease Locus. Science 269, 973-977.[Abstract/Free Full Text]

Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J (1951). Protein mearsurement with the Folin Phenol reagent. J. Biol. Chem 193, 265-275.[Free Full Text]

Neophytou, P. I., Muir, E. M. and Hutton, J. C (1996). A subtractive cloning approach to the identification of mRNAs specifically expressed in pancreatic beta cells. Diabetes 45, 127-133.[Abstract]

Page, R., Hattersley, A. T. and Turner, R. C (1992). Beta cell secretory defect casued by mutations in glucokinase gene. Lancet 340, 444-448.[Medline]

Porte, D. and Kahn, S. E (1989). Hyperproinsulinaemia and amyloid inNIDDM: Clues to etiology of iselt \247-cell dysfunction. Diabetes 38, 1333-1336.[Abstract]

Rogaev, E. I., Sherrington, R., Rogaeva, E. A., Levesque, G., Ikeda, M., Liang, Y., Chi, H., Lin, C., Holman, K., Tsuda, T., et al (1995). Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775-778.[Medline]

Sanke, T., Bell, G. I., Sample, C., Rubenstein, A. H. and Steiner, D. F (1988). An islet amyloid peptide is derived from an 89 amino acid precursor by proteolytic processing. J Biol. Chem 263, 17243-17246.[Abstract/Free Full Text]

Sanke, T., Hanabusa, T., Nakamo, Y., Oki, C., Okai, K., Nishimura, S., Kondo, M. and Nanjo, K (1991). . Plasma islet amyloid polypeptide (amylin) levels and their responses to oral glucose in Type 2 (non-insulin-dependent) diabetic patients. Diabetologia 34, 129-132.[Medline]

Schnell, A. H., Swenne, I. and Borg, L. A. H (1988). Lysosomes and pancreatic islet function: a quantitative estimation of crinophagy in the mouse pancreatic-cell. Cell Tissue Res 252, 9-15.[Medline]

Sherrington, R., Rogaev, E. I., Liang, Y., Rogaeva, E. A., Levesque, G., Ikeda, M., Chi, H., Lin, C., Li, G., Holman, K. et al (1995). . Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375, 754-760.[Medline]

Sherrington, R., Froelich, S., Sorbi, S., Champion, D., Chi, H., Rogaeva, E. A., Levesque, G., Rogaev, E. I., Lin, C., Liang, Y. et al (1996). Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant. Human Mol. Genet 5, 985-988.[Abstract/Free Full Text]

Stoffers, D. A., Ferrer, J., Clarke, W. L. and Habner, J. F (1997). Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nature Genet 17, 138-139.[Medline]

Thinakaran, G., Borchelt, D. R., Lee, M. K., Slunt, H. H., Spitzer, L., Kim, G., Ratovitsky, T., Davenport, F., Nordstedt, C., Seeger, M. et al (1996). . Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron 17, 181-190.[Medline]

Tian, Y. M., Urquidi, V. and Ashcroft, S. J (1996). Protein kinase Cinbetacells: expression of multiple isoforms and involvement in cholinergic stimulation of insulin secretion. Mol. Cell Endocrinol 119, 185-193.[Medline]

Vito, P., Lacana, E. and D'Adamio, L (1996). Interfering with apoptosis: Ca2+ binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science 271, 521-525.[Abstract]

Vito, P., Wolozin, B., Ganjei, J. K., Iwasaki, K., Lacana, E., D'Adamio, L (1996). Requirement of familial Alzheimer's disease gene PS2 forapoptosis. Opposing effect of ALG-3. J. Biol. Chem 271, 31025-31028.[Abstract/Free Full Text]

Walter, J., Capell, A., Grunberg, J., Pesold, B., Schindzeilorz, A., Prior, R., Podlisny, M. B., Fraser, P. E., St George-Hyslop, P. H., Selkoe, D. J. and Haas, C (1996). The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum. Mol. Med 2, 673-691.[Medline]

Westermark, P., Wernstedt, C., Wilander, E., Hayden, D. W., O'Brien, T. D. and Johnson, K. H (1987). . Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells. Proc. Nat. Acad Sci. USA 84, 3881-3885.[Abstract/Free Full Text]

Westermark, P. and Grimelius, L (1973). The pancreatic islet cell in insular amyloidosis in human diabetic and non-diabetic islets. Acta Pathol. Microbiol. Scand -. A 81, 291-300.

Wolozin, B., Iwasaki, K., Vito, P., Ganjei, J. K., Lacana, E., Sunderland, T., Zhao, B., Kusiak, J. W., Wasco, W. and D'Adamio, L (1996). Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science 274, 1710-1713.[Abstract/Free Full Text]

Xia, W., Zhang, J., Kholodenko, D., Citron, M., Podlisny, M. B., Teplow, D. B. et al (1997). Enhanced production and oligomerization of the 42-residue amyloid B-protein by chinese hamster ovary cells stably expressing mutant presenilins. J. Biol. Chem 272, 7977-7982.[Abstract/Free Full Text]

Yamagata, K., Furuta, H., Oda, N., Kaisaki, P. J., Menzel, S., Cox, N. J., Fajans, S. S., Signorini, S., Stoffel, M. and Bell, G. I (1996). Mutations in hepatic nuclear factor alpha gene in maturity onset diabetes of the young (MODY 1). Nature 384, 458-460.[Medline]

Yu, G, Chen, F., Levesque, G., Nishimura, M., Zhang, D. M., Levesque, L., Rogaeva, E., Xu, D., Liang, Y., Duthie, M., St George-Hyslop, P. H. and Fraser, P. E (1998). The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains-catenin. J. Biol. Chem 273, 16470-16475.[Abstract/Free Full Text]

Zang, Z., Hartmann, H., Do, V. M., Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., de Wetering, M., Clevers, H., Saftig, P., de Strooper, B., He, X. and Yankner, B. A (1998). Destabilization of-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 395, 698-702.[Medline]




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