The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression

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Atherton, F. S., Liu, F., Gabrielli, B., Lee, M. S., Peng, C. Y. and Piwnica-Worms, H (1994). Cell cycle regulation of the p34cdc2 inhibitory kinases. Mol. Biol. Cell 5, 989-1001.[Abstract]

Audit, M., Barbier, M., Soyer-Gobillard, M. O., Albert, M., Geraud, M. L., Nicolas, G. and Lenaers, G (1996). Cyclin B (p56cdc13) localization in the yeast Schizosaccharomyces pombe: an ultrastructural and immunocytochemical study. Biol. Cell 86, 1-10.[Medline]

Booher, R. N., Holman, P. S. and Fattaey, A (1997). Human myt1 is a cell cycle-regulated kinase that inhibits cdc2 but not cdk2 activity. J. Biol. Chem 272, 22300-22306.[Abstract/Free Full Text]

Coleman, T. R. and Dunphy, W. G (1994). Cdc2 regulatory factors. Curr. Opin. Cell Biol 6, 877-882.[Medline]

Crenshaw, D. G., Yang, J., Means, A. R. and Kornbluth, S (1998). The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1. EMBO J 17, 1315-1327.[Medline]

Davis, F. M., Tsao, T. Y., Fowler, S. K. and Rao, P. N (1983). Monoclonal antibodies to mitotic cells. Proc. Nat. Acad. Sci. USA 80, 2926-2930.[Abstract/Free Full Text]

Den Haese, G. J., Walworth, N., Carr, A. M. and Gould, K. L (1995). The Wee1 protein kinase regulates T14 phosphorylation of fission yeast Cdc2. Mol. Biol. Cell 6, 371-385.[Abstract]

Forsburg, S. L. and Sherman, D. A (1997). General purpose tagging vectors for fission yeast. Gene 191, 191-195.[Medline]

Hagting, A., Karlsson, C., Clute, P., Jackman, M. and Pines, J (1998). MPF localization is controlled by nuclear export. EMBO J 17, 4127-4138.[Medline]

Heald, R., McLoughlin, M. and McKeon, F (1993). Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase. Cell 74, 463-474.[Medline]

Heintz, N., Sive, H. L. and Roeder, R. G (1983). Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Mol. Cell. Biol 3, 539-550.[Abstract/Free Full Text]

Igarashi, M., Nagata, A., Jinno, S., Suto, K. and Okayama, H (1991). Wee1(+)-like gene in human cells. Nature 353, 80-83.[Medline]

Janknecht, R (1996). Analysis of the ERK-stimulated ETS transcription factor ER81. Mol. Cell. Biol 16, 1550-1556.[Abstract]

Jiang, W. and Hunter, T (1998). Analysis of cell-cycle profiles in transfected cells using a membrane-targeted GFP. Biotechniques 24, 349-354.[Medline]

Jin, P., Gu, Y. and Morgan, D. O (1996). Role of inhibitory CDC2 phosphorylation in radiation-induced G2arrest in human cells. J. Cell Biol 134, 963-970.[Abstract/Free Full Text]

Jin, P., Hardy, S. and Morgan, D. O (1998). Nuclear localization of cyclinB1 controls mitotic entry after DNA damage. J. Cell Biol 141, 875-885.[Abstract/Free Full Text]

Kanemitsu, M. Y., Jiang, W. and Eckhart, W (1998). Cdc2-mediated phosphorylation of the gap junction protein, connexin43, during mitosis. Cell Growth Differ 9, 13-21.[Abstract]

Kornbluth, S., Sebastian, B., Hunter, T. and Newport, J (1994). Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14. Mol. Biol. Cell 5, 273-282.[Abstract]

Kumagai, A. and Dunphy, W. G (1995). Control of the Cdc2/cyclin B complex in Xenopus egg extracts arrested at a G2/M checkpoint with DNA synthesis inhibitors. Mol. Biol. Cell 6, 199-213.[Abstract]

Li, J., Meyer, A. N. and Donoghue, D. J (1997). Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation. Proc. Nat. Acad. Sci. USA 94, 502-507.[Abstract/Free Full Text]

Liu, F., Stanton, J. J., Wu, Z. and Piwnica-Worms, H (1997). The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex. Mol. Cell. Biol 17, 571-583.[Abstract]

Liu, F., Rothblum-Oviatt, C., Ryan, C. E. and Piwnica-Worms, H (1999). Overproduction of human Myt1 kinase induces a G2cell cycle delay by interfering with the intracellular trafficking of Cdc2-cyclin B1 complexes. Mol. Cell. Biol 19, 5133-5123.

Lu, K. P., Hanes, S. D. and Hunter, T (1996). A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature 380, 544-547.[Medline]

Lu, P. J., Zhou, X. Z., Shen, M. and Lu, K. P (1999). Function of WW domains as phosphoserine-or phosphothreonine-binding modules. Science 283, 1325-1328.[Abstract/Free Full Text]

McGowan, C. H. and Russell, P (1995). Cell cycle regulation of human WEE1. EMBO J 14, 2166-2175.[Medline]

Morgan, D. O (1997). Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell. Dev. Biol 13, 261-291.[Medline]

Mueller, P. R., Coleman, T. R., Kumagai, A. and Dunphy, W. G (1995). Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15. Science 270, 86-90.[Abstract/Free Full Text]

Norbury, C., Blow, J. and Nurse, P (1991). Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. EMBO J 10, 3321-3329.[Medline]

Norbury, C. and Nurse, P (1992). Animal cell cycles and their control. Annu. Rev. Biochem 61, 441-470.[Medline]

Pagano, M., Pepperkok, R., Lukas, J., Baldin, V., Ansorge, W., Bartek, J. and Draetta, G (1993). Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts. J. Cell Biol 121, 101-111.[Abstract/Free Full Text]

Palmer, A., Gavin, A. C. and Nebreda, A. R (1998). A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1. EMBO J 17, 5037-5047.[Medline]

Parker, L. L., Sylvestre, P. J., Byrnes, M. r., Liu, F. and Piwnica-Worms, H (1995). Identification of a 95-kDa WEE1-like tyrosine kinase in HeLa cells. Proc. Nat. Acad. Sci. USA 92, 9638-9642.[Abstract/Free Full Text]

Pines, J. and Hunter, T (1991). Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. J. Cell Biol 115, 1-17.[Abstract/Free Full Text]

Pines, J. and Hunter, T (1994). The differential localization of human cyclins A and B is due to a cytoplasmic retention signal in cyclin B. EMBO J 13, 3772-3781.[Medline]

Poon, R. Y., Chau, M. S., Yamashita, K. and Hunter, T (1997). The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells. Cancer Res 57, 5168-5178.[Abstract/Free Full Text]

Ranganathan, R., Lu, K. P., Hunter, T. and Noel, J. P (1997). Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell 89, 875-886.[Medline]

Schmid, F. X (1995). Protein folding. Prolyl isomerases join the fold. Curr. Biol 5, 993-994.[Medline]

Shen, M., Stukenberg, P. T., Kirschner, M. W. and Lu, K. P (1998). The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Genes Dev 12, 706-720.[Abstract/Free Full Text]

Solomon, M. J., Lee, T. and Kirschner, M. W (1992). Role of phosphorylation in p34cdc2 activation: identification of an activating kinase. Mol. Biol. Cell 3, 13-27.[Abstract]

van den Heuvel, S. and Harlow, E (1993). Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262, 2050-2054.[Abstract/Free Full Text]

Watanabe, N., Broome, M. and Hunter, T (1995). Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle. EMBO J 14, 1878-1891.[Medline]

Westendorf, J. M., Rao, P. N. and Gerace, L (1994). Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc. Nat. Acad. Sci. USA 91, 714-718.[Abstract/Free Full Text]

Yaffe, M. B., Schutkowski, M., Shen, M., Zhou, X. Z., Stukenberg, P. T., Rahfeld, J. U., Xu, J., Kuang, J., Kirschner, M. W., Fischer, G. et al (1997). Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science 278, 1957-1960.[Abstract/Free Full Text]

Yang, J., Bardes, E. S., Moore, J. D., Brennan, J., Powers, M. A. and Kornbluth, S (1998). Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1. Genes Dev 12, 2131-2143.[Abstract/Free Full Text]

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				Z. Jin, E. Homola, S. Tiong, and S. D. Campbell Drosophila Myt1 Is the Major Cdk1 Inhibitory Kinase for Wing Imaginal Disc Development Genetics, December 1, 2008; 180(4): 2123 - 2133. [Abstract] [Full Text] [PDF]

				H. Nakajima, S. Yonemura, M. Murata, N. Nakamura, H. Piwnica-Worms, and E. Nishida Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit J. Cell Biol., April 3, 2008; 181(1): 89 - 103. [Abstract] [Full Text] [PDF]

				C. Seidl, M. Port, K.-P. Gilbertz, A. Morgenstern, F. Bruchertseifer, M. Schwaiger, B. Roper, R. Senekowitsch-Schmidtke, and M. Abend 213Bi-induced death of HSC45-M2 gastric cancer cells is characterized by G2 arrest and up-regulation of genes known to prevent apoptosis but induce necrosis and mitotic catastrophe Mol. Cancer Ther., August 1, 2007; 6(8): 2346 - 2359. [Abstract] [Full Text] [PDF]

				B. A. Bryan, O. F. Dyson, and S. M. Akula Identifying cellular genes crucial for the reactivation of Kaposi's sarcoma-associated herpesvirus latency. J. Gen. Virol., March 1, 2006; 87(Pt 3): 519 - 529. [Abstract] [Full Text] [PDF]

				Z. Jin, E. M. Homola, P. Goldbach, Y. Choi, J. A. Brill, and S. D. Campbell Drosophila Myt1 is a Cdk1 inhibitory kinase that regulates multiple aspects of cell cycle behavior during gametogenesis Development, September 15, 2005; 132(18): 4075 - 4085. [Abstract] [Full Text] [PDF]

				I.-M. Kim, S. Ramakrishna, G. A. Gusarova, H. M. Yoder, R. H. Costa, and V. V. Kalinichenko The Forkhead Box M1 Transcription Factor Is Essential for Embryonic Development of Pulmonary Vasculature J. Biol. Chem., June 10, 2005; 280(23): 22278 - 22286. [Abstract] [Full Text] [PDF]

				A.-C. Goulet, M. Chigbrow, P. Frisk, and M. A. Nelson Selenomethionine induces sustained ERK phosphorylation leading to cell-cycle arrest in human colon cancer cells Carcinogenesis, January 1, 2005; 26(1): 109 - 117. [Abstract] [Full Text] [PDF]

				S. Chen and D. G. Gardner Suppression of WEE1 and Stimulation of CDC25A Correlates with Endothelin-dependent Proliferation of Rat Aortic Smooth Muscle Cells J. Biol. Chem., April 2, 2004; 279(14): 13755 - 13763. [Abstract] [Full Text] [PDF]

				M. L. Major, R. Lepe, and R. H. Costa Forkhead Box M1B Transcriptional Activity Requires Binding of Cdk-Cyclin Complexes for Phosphorylation-Dependent Recruitment of p300/CBP Coactivators Mol. Cell. Biol., April 1, 2004; 24(7): 2649 - 2661. [Abstract] [Full Text] [PDF]

				N. Watanabe, H. Arai, Y. Nishihara, M. Taniguchi, N. Watanabe, T. Hunter, and H. Osada M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCF{beta}-TrCP PNAS, March 30, 2004; 101(13): 4419 - 4424. [Abstract] [Full Text] [PDF]

				V. Sanchez, A. K. McElroy, and D. H. Spector Mechanisms Governing Maintenance of Cdk1/Cyclin B1 Kinase Activity in Cells Infected with Human Cytomegalovirus J. Virol., December 15, 2003; 77(24): 13214 - 13224. [Abstract] [Full Text] [PDF]

				J. P. H. Chow, W. Y. Siu, H. T. B. Ho, K. H. T. Ma, C. C. Ho, and R. Y. C. Poon Differential Contribution of Inhibitory Phosphorylation of CDC2 and CDK2 for Unperturbed Cell Cycle Control and DNA Integrity Checkpoints J. Biol. Chem., October 17, 2003; 278(42): 40815 - 40828. [Abstract] [Full Text] [PDF]

				B. J. Passer, V. Nancy-Portebois, N. Amzallag, S. Prieur, C. Cans, A. Roborel de Climens, G. Fiucci, V. Bouvard, M. Tuynder, L. Susini, et al. The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase PNAS, March 4, 2003; 100(5): 2284 - 2289. [Abstract] [Full Text] [PDF]

				A. Ryo, Y.-C. Liou, K. P. Lu, and G. Wulf Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer J. Cell Sci., March 1, 2003; 116(5): 773 - 783. [Abstract] [Full Text] [PDF]

				H.-k. Huang, S. L. Forsburg, U. P. John, M. J. O'Connell, and T. Hunter Isolation and characterization of the Pin1/Ess1p homologue in Schizosaccharomyces pombe J. Cell Sci., March 12, 2002; 114(20): 3779 - 3788. [Abstract] [Full Text] [PDF]

				S. T. Lamitina and S. W. L'Hernault Dominant mutations in the Caenorhabditis elegans Myt1 ortholog wee-1.3 reveal a novel domain that controls M-phase entry during spermatogenesis Development, January 11, 2002; 129(21): 5009 - 5018. [Abstract] [Full Text] [PDF]

				C. J. Rothblum-Oviatt, C. E. Ryan, and H. Piwnica-Worms 14-3-3 Binding Regulates Catalytic Activity of Human Wee1 Kinase Cell Growth Differ., December 1, 2001; 12(12): 581 - 589. [Abstract] [Full Text] [PDF]

				J. R. Thorpe, S. J. Morley, and S. L. Rulten Utilizing the Peptidyl-Prolyl Cis-Trans Isomerase Pin1 as a Probe of Its Phosphorylated Target Proteins: Examples of Binding to Nuclear Proteins in a Human Kidney Cell Line and to Tau in Alzheimer's Diseased Brain J. Histochem. Cytochem., January 1, 2001; 49(1): 97 - 108. [Abstract] [Full Text]